DE602004026077D1 - Erstellung von expressionsprofilen unter verwendung von mikroarrays - Google Patents

Erstellung von expressionsprofilen unter verwendung von mikroarrays

Info

Publication number
DE602004026077D1
DE602004026077D1 DE602004026077T DE602004026077T DE602004026077D1 DE 602004026077 D1 DE602004026077 D1 DE 602004026077D1 DE 602004026077 T DE602004026077 T DE 602004026077T DE 602004026077 T DE602004026077 T DE 602004026077T DE 602004026077 D1 DE602004026077 D1 DE 602004026077D1
Authority
DE
Germany
Prior art keywords
methods
microarrays
preparation
microarray
expression profiles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004026077T
Other languages
German (de)
English (en)
Inventor
Joseph Monforte
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Althea Inc
Original Assignee
Althea Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Althea Technologies Inc filed Critical Althea Technologies Inc
Publication of DE602004026077D1 publication Critical patent/DE602004026077D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809Methods for determination or identification of nucleic acids involving differential detection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE602004026077T 2003-09-10 2004-09-10 Erstellung von expressionsprofilen unter verwendung von mikroarrays Expired - Lifetime DE602004026077D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50210803P 2003-09-10 2003-09-10
US53828304P 2004-01-21 2004-01-21
PCT/US2004/029749 WO2005042759A2 (en) 2003-09-10 2004-09-10 Expression profiling using microarrays

Publications (1)

Publication Number Publication Date
DE602004026077D1 true DE602004026077D1 (de) 2010-04-29

Family

ID=34555682

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004026077T Expired - Lifetime DE602004026077D1 (de) 2003-09-10 2004-09-10 Erstellung von expressionsprofilen unter verwendung von mikroarrays

Country Status (9)

Country Link
US (2) US7824856B2 (enExample)
EP (1) EP1660674B1 (enExample)
JP (1) JP5171037B2 (enExample)
AT (1) ATE461292T1 (enExample)
AU (1) AU2004286201B2 (enExample)
CA (1) CA2536565A1 (enExample)
DE (1) DE602004026077D1 (enExample)
SG (1) SG149007A1 (enExample)
WO (1) WO2005042759A2 (enExample)

Families Citing this family (196)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6913697B2 (en) 2001-02-14 2005-07-05 Science & Technology Corporation @ Unm Nanostructured separation and analysis devices for biological membranes
EP1569510B1 (en) 2002-09-27 2011-11-02 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
EP1907571B1 (en) 2005-06-15 2017-04-26 Complete Genomics Inc. Nucleic acid analysis by random mixtures of non-overlapping fragments
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
EP1915181A4 (en) * 2005-08-10 2009-07-15 Merck & Co Inc NEW HIV TARGETS
JP2009536313A (ja) 2006-01-11 2009-10-08 レインダンス テクノロジーズ, インコーポレイテッド ナノリアクターの形成および制御において使用するマイクロ流体デバイスおよび方法
WO2007092538A2 (en) * 2006-02-07 2007-08-16 President And Fellows Of Harvard College Methods for making nucleotide probes for sequencing and synthesis
ATE540750T1 (de) 2006-05-11 2012-01-15 Raindance Technologies Inc Mikrofluidische vorrichtung und verfahren
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
US8148085B2 (en) * 2006-05-15 2012-04-03 Sea Lane Biotechnologies, Llc Donor specific antibody libraries
EP2024393A2 (en) * 2006-05-15 2009-02-18 Sea Lane Biotechnologies,llc. Neutralizing antibodies to influenza viruses
EP2589668A1 (en) 2006-06-14 2013-05-08 Verinata Health, Inc Rare cell analysis using sample splitting and DNA tags
US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
CA2669728C (en) 2006-11-15 2017-04-11 Biospherex Llc Multitag sequencing and ecogenomics analysis
WO2008076375A2 (en) * 2006-12-13 2008-06-26 Autogenomics, Inc. Concurrent analysis of multiple patient samples using solid phase addressable multiplex test with high signal-to-noise ratio
WO2008076374A2 (en) * 2006-12-13 2008-06-26 Autogenomics, Inc. Devices and methods of anonymously deconvoluting combined patient samples and combined patient assays
WO2008080029A2 (en) 2006-12-21 2008-07-03 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
US8772046B2 (en) 2007-02-06 2014-07-08 Brandeis University Manipulation of fluids and reactions in microfluidic systems
EP1978104A1 (en) * 2007-04-03 2008-10-08 Freie Universität Berlin A method for the quantitative analysis of RNA molecules in a sample
US8592221B2 (en) 2007-04-19 2013-11-26 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
CA2697640C (en) 2007-09-21 2016-06-21 Katholieke Universiteit Leuven Tools and methods for genetic tests using next generation sequencing
US8932879B2 (en) * 2007-11-06 2015-01-13 Ambergen, Inc. Methods and compounds for phototransfer
US8906700B2 (en) 2007-11-06 2014-12-09 Ambergen, Inc. Methods and compositions for phototransfer
US8592150B2 (en) 2007-12-05 2013-11-26 Complete Genomics, Inc. Methods and compositions for long fragment read sequencing
US20090163366A1 (en) * 2007-12-24 2009-06-25 Helicos Biosciences Corporation Two-primer sequencing for high-throughput expression analysis
WO2009086353A1 (en) * 2007-12-26 2009-07-09 Helicos Biosciences Corporation Improved two-primer sequencing for high-throughput expression analysis
US12038438B2 (en) 2008-07-18 2024-07-16 Bio-Rad Laboratories, Inc. Enzyme quantification
EP4047367A1 (en) 2008-07-18 2022-08-24 Bio-Rad Laboratories, Inc. Method for detecting target analytes with droplet libraries
US8697363B2 (en) * 2008-08-26 2014-04-15 Fluidigm Corporation Methods for detecting multiple target nucleic acids in multiple samples by use nucleotide tags
US8528589B2 (en) 2009-03-23 2013-09-10 Raindance Technologies, Inc. Manipulation of microfluidic droplets
US20120010091A1 (en) 2009-03-30 2012-01-12 Illumina, Inc. Gene expression analysis in single cells
US8691509B2 (en) 2009-04-02 2014-04-08 Fluidigm Corporation Multi-primer amplification method for barcoding of target nucleic acids
WO2010127186A1 (en) 2009-04-30 2010-11-04 Prognosys Biosciences, Inc. Nucleic acid constructs and methods of use
AU2010266234B2 (en) 2009-07-01 2013-07-25 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
CN102639714A (zh) * 2009-10-29 2012-08-15 日本碍子株式会社 靶核酸的检测方法
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
JP5934657B2 (ja) 2010-02-12 2016-06-15 レインダンス テクノロジーズ, インコーポレイテッド デジタル検体分析
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
RS54482B1 (sr) 2010-04-05 2016-06-30 Prognosys Biosciences, Inc. Biološka testiranja sa prostornim kodiranjem
EP3447155A1 (en) 2010-09-30 2019-02-27 Raindance Technologies, Inc. Sandwich assays in droplets
GB201018312D0 (en) * 2010-10-29 2010-12-15 Vib Vzw Metagene expression signature for prognosis of breast cancer patients
EP2455485A1 (de) 2010-11-19 2012-05-23 Anagnostics Bioanalysis GmbH Verfahren zum Nachweis von Nukleinsäuren
US20140121118A1 (en) * 2010-11-23 2014-05-01 Opx Biotechnologies, Inc. Methods, systems and compositions regarding multiplex construction protein amino-acid substitutions and identification of sequence-activity relationships, to provide gene replacement such as with tagged mutant genes, such as via efficient homologous recombination
US9364803B2 (en) 2011-02-11 2016-06-14 Raindance Technologies, Inc. Methods for forming mixed droplets
US9150852B2 (en) 2011-02-18 2015-10-06 Raindance Technologies, Inc. Compositions and methods for molecular labeling
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
EP3395957B1 (en) 2011-04-25 2020-08-12 Bio-Rad Laboratories, Inc. Methods and compositions for nucleic acid analysis
DK2702146T3 (en) * 2011-04-28 2019-03-11 Univ Leland Stanford Junior IDENTIFICATION OF POLYNUCLEOTIDES CONNECTED WITH A SAMPLE
SG194745A1 (en) 2011-05-20 2013-12-30 Fluidigm Corp Nucleic acid encoding reactions
EP2714970B1 (en) 2011-06-02 2017-04-19 Raindance Technologies, Inc. Enzyme quantification
US8841071B2 (en) * 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
EP2559774A1 (en) * 2011-08-17 2013-02-20 Roche Diagniostics GmbH Improved method for amplification of target nucleic acids using a multi-primer approach
US20150252413A1 (en) * 2011-11-07 2015-09-10 Bioquanta Method for normalization of quantitative pcr and microarrays
SI3363901T1 (sl) 2012-02-17 2021-04-30 Fred Hutchinson Cancer Research Center Sestavki in postopki za natančno identifikacijo mutacij
GB2513024B (en) 2012-02-27 2016-08-31 Cellular Res Inc A clonal amplification method
ES2905448T3 (es) 2012-05-10 2022-04-08 Massachusetts Gen Hospital Métodos para determinar una secuencia nucleotídica
EP2852682B1 (en) 2012-05-21 2017-10-04 Fluidigm Corporation Single-particle analysis of particle populations
DK2867361T3 (da) 2012-06-29 2018-01-29 Massachusetts Inst Technology Omfangsrig parallel kombinatorisk genetik
CA2877740A1 (en) * 2012-07-03 2014-01-09 Integrated Dna Technologies, Inc. Tm-enhanced blocking oligonucleotides and baits for improved target enrichment and reduced off-target selection
USRE50065E1 (en) 2012-10-17 2024-07-30 10X Genomics Sweden Ab Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
EP2943590A4 (en) 2013-01-13 2017-02-15 Unitaq Bio Methods and compositions for pcr using blocked and universal primers
JP6437522B2 (ja) 2013-03-15 2018-12-12 ベックマン コールター, インコーポレイテッド フローサイトメトリーにおけるパネル設計のためのシステム及び方法
JP6433982B2 (ja) * 2013-04-19 2018-12-05 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドSiemens Healthcare Diagnostics Inc. 無接触微小滴ディスペンサおよび方法
CN105849275B (zh) 2013-06-25 2020-03-17 普罗格诺西斯生物科学公司 检测样品中生物靶标的空间分布的方法和系统
ES2857908T3 (es) * 2013-08-28 2021-09-29 Becton Dickinson Co Análisis masivamente paralelo de células individuales
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
WO2015054292A1 (en) 2013-10-07 2015-04-16 Cellular Research, Inc. Methods and systems for digitally counting features on arrays
AU2014346399A1 (en) 2013-11-11 2016-06-02 Arizona Board Of Regents On Behalf Of Northern Arizona University Systems and methods for universal tail-based indexing strategies for amplicon sequencing
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
WO2015112974A1 (en) 2014-01-27 2015-07-30 The General Hospital Corporation Methods of preparing nucleic acids for sequencing
EP3763825B1 (en) * 2015-01-23 2023-10-04 Qiagen Sciences, LLC High multiplex pcr with molecular barcoding
CN107250379B (zh) 2015-02-19 2021-12-28 贝克顿迪金森公司 结合蛋白质组信息和基因组信息的高通量单细胞分析
ES2836802T3 (es) 2015-02-27 2021-06-28 Becton Dickinson Co Códigos de barras moleculares espacialmente direccionables
EP3274466A4 (en) * 2015-03-24 2018-11-21 Sigma Aldrich Co. LLC Directional amplification of rna
EP4180535A1 (en) * 2015-03-30 2023-05-17 Becton, Dickinson and Company Methods and compositions for combinatorial barcoding
HK1250245A1 (zh) 2015-04-10 2018-12-07 Spatial Transcriptomics Ab 生物样本的空间区别、多重核酸分析
US10385387B2 (en) 2015-04-20 2019-08-20 Pacific Biosciences Of California, Inc. Methods for selectively amplifying and tagging nucleic acids
EP4582556A3 (en) 2015-04-23 2025-10-08 Becton, Dickinson and Company Methods and compositions for whole transcriptome amplification
US11124823B2 (en) 2015-06-01 2021-09-21 Becton, Dickinson And Company Methods for RNA quantification
US20170002405A1 (en) * 2015-06-30 2017-01-05 Nanostring Technologies, Inc. Methods and kits for simultaneously detecting gene or protein expression in a plurality of sample types using self-assembling fluorescent barcode nanoreporters
AU2016313095A1 (en) * 2015-08-24 2017-11-23 Qiagen Gmbh Method for generating a RNA-sequencing library
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
ES2745694T3 (es) 2015-09-11 2020-03-03 Cellular Res Inc Métodos y composiciones para normalización de biblioteca de ácido nucleico
US20170130258A1 (en) * 2015-11-10 2017-05-11 Agilent Technologies, Inc. Multiplex on-array droplet pcr and quantitative pcr
CA3006994A1 (en) 2015-12-16 2017-06-22 Fluidigm Corporation High-level multiplex amplification
WO2017120524A1 (en) * 2016-01-07 2017-07-13 The Board Of Trustees Of The Leland Stanford Junior University Defined enzymatic synthesis of lipid a analogs
CN105674603B (zh) * 2016-01-13 2017-12-08 泰兴市城东绿化工程有限公司 一种具有自动气体检测功能的太阳能集热器
US10844426B2 (en) 2016-03-17 2020-11-24 President And Fellows Of Harvard College Methods for detecting and identifying genomic nucleic acids
CN115896099A (zh) * 2016-03-31 2023-04-04 伯克利之光生命科技公司 核酸稳定试剂、试剂盒及其使用方法
AU2017261189B2 (en) 2016-05-02 2023-02-09 Becton, Dickinson And Company Accurate molecular barcoding
US10301677B2 (en) 2016-05-25 2019-05-28 Cellular Research, Inc. Normalization of nucleic acid libraries
ES2979395T3 (es) 2016-05-26 2024-09-25 Becton Dickinson Co Métodos de ajuste del recuento de etiquetas moleculares
US10202641B2 (en) 2016-05-31 2019-02-12 Cellular Research, Inc. Error correction in amplification of samples
US10640763B2 (en) 2016-05-31 2020-05-05 Cellular Research, Inc. Molecular indexing of internal sequences
JP6997772B2 (ja) 2016-09-15 2022-01-18 アーチャーディーエックス, エルエルシー 核酸サンプル調製の方法
EP4353830A3 (en) 2016-09-15 2024-07-03 ArcherDX, LLC Methods of nucleic acid sample preparation for analysis of cell-free dna
KR102522023B1 (ko) 2016-09-26 2023-04-17 셀룰러 리서치, 인크. 바코딩된 올리고뉴클레오티드 서열을 갖는 시약을 이용한 단백질 발현의 측정
US11608497B2 (en) 2016-11-08 2023-03-21 Becton, Dickinson And Company Methods for cell label classification
WO2018089378A1 (en) 2016-11-08 2018-05-17 Cellular Research, Inc. Methods for expression profile classification
JP7104048B2 (ja) 2017-01-13 2022-07-20 セルラー リサーチ, インコーポレイテッド 流体チャネルの親水性コーティング
EP3577232A1 (en) 2017-02-01 2019-12-11 Cellular Research, Inc. Selective amplification using blocking oligonucleotides
CN110573629B (zh) * 2017-03-30 2024-08-13 伊利诺伊大学理事会 用于诊断早期胰腺癌的方法和试剂盒
US11584958B2 (en) 2017-03-31 2023-02-21 Grail, Llc Library preparation and use thereof for sequencing based error correction and/or variant identification
KR102790050B1 (ko) 2017-06-05 2025-04-04 백톤 디킨슨 앤드 컴퍼니 단일 세포를 위한 샘플 인덱싱
AU2018378827B2 (en) * 2017-12-07 2023-04-13 Massachusetts Institute Of Technology Single cell analyses
CN111492068B (zh) 2017-12-19 2025-03-21 贝克顿迪金森公司 与寡核苷酸相关联的颗粒
CN108546741B (zh) * 2018-03-02 2021-07-20 吉林农业科技学院 一种玉米转抗草丁膦抗性基因成分nasba-elisa快速检测试剂盒及检测方法
WO2019199579A1 (en) * 2018-04-09 2019-10-17 The Board Of Trustees Of The Leland Stanford Junior University Method of in situ gene sequencing
WO2019213294A1 (en) 2018-05-03 2019-11-07 Becton, Dickinson And Company High throughput multiomics sample analysis
EP4545647A3 (en) 2018-05-03 2025-07-09 Becton, Dickinson and Company Molecular barcoding on opposite transcript ends
US20190352712A1 (en) * 2018-05-04 2019-11-21 Shoreline Biome, Llc Multiple Specific/Nonspecific Primers for PCR of a Complex Gene Pool
US11519033B2 (en) 2018-08-28 2022-12-06 10X Genomics, Inc. Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample
US20210324457A1 (en) * 2018-08-28 2021-10-21 Eswar Prasad Ramachandran Iyer Methods for Generating Spatially Barcoded Arrays
CN110885899B (zh) * 2018-09-10 2023-04-14 中国动物疫病预防控制中心(农业部屠宰技术中心) 用于鉴别16种禽病病原冻干微芯片、试剂盒及方法
CN109378038A (zh) * 2018-09-17 2019-02-22 上海派森诺生物科技股份有限公司 一种基于bsa基因定位的自动化分析方法
EP4471156A3 (en) 2018-10-01 2025-02-26 Becton, Dickinson and Company Determining 5' transcript sequences
JP7618548B2 (ja) 2018-11-08 2025-01-21 ベクトン・ディキンソン・アンド・カンパニー ランダムプライミングを使用した単一細胞の全トランスクリプトーム解析
WO2020123318A1 (en) 2018-12-10 2020-06-18 10X Genomics, Inc. Resolving spatial arrays using deconvolution
WO2020123384A1 (en) 2018-12-13 2020-06-18 Cellular Research, Inc. Selective extension in single cell whole transcriptome analysis
US11926867B2 (en) 2019-01-06 2024-03-12 10X Genomics, Inc. Generating capture probes for spatial analysis
US11649485B2 (en) 2019-01-06 2023-05-16 10X Genomics, Inc. Generating capture probes for spatial analysis
EP3908668A4 (en) 2019-01-11 2022-11-09 University of Virginia Patent Foundation COMPOSITIONS AND METHODS FOR PREDICTING LUNG FUNCTION DECLINE RELATED TO IDIOPATHIC PULMONARY FIBROSIS
WO2020150356A1 (en) 2019-01-16 2020-07-23 Becton, Dickinson And Company Polymerase chain reaction normalization through primer titration
ES2989967T3 (es) 2019-01-23 2024-11-28 Becton Dickinson Co Oligonucleótidos asociados con anticuerpos
US12071617B2 (en) 2019-02-14 2024-08-27 Becton, Dickinson And Company Hybrid targeted and whole transcriptome amplification
WO2020214642A1 (en) 2019-04-19 2020-10-22 Becton, Dickinson And Company Methods of associating phenotypical data and single cell sequencing data
US12498378B2 (en) 2019-04-23 2025-12-16 Encodia, Inc. Methods for spatial analysis of proteins and related kits
WO2020236846A1 (en) * 2019-05-20 2020-11-26 Encodia, Inc. Methods and related kits for spatial analysis
EP3976820A1 (en) 2019-05-30 2022-04-06 10X Genomics, Inc. Methods of detecting spatial heterogeneity of a biological sample
CN120099137A (zh) 2019-07-22 2025-06-06 贝克顿迪金森公司 单细胞染色质免疫沉淀测序测定
WO2021092433A2 (en) 2019-11-08 2021-05-14 10X Genomics, Inc. Enhancing specificity of analyte binding
CN114729350A (zh) 2019-11-08 2022-07-08 贝克顿迪金森公司 使用随机引发获得用于免疫组库测序的全长v(d)j信息
WO2021118435A1 (en) * 2019-12-09 2021-06-17 Laboratorios Maymó S.A. Rapid amplification and genotyping of nucleic acid sequences
EP4081656A1 (en) 2019-12-23 2022-11-02 10X Genomics, Inc. Compositions and methods for using fixed biological samples in partition-based assays
ES2982420T3 (es) 2019-12-23 2024-10-16 10X Genomics Inc Métodos para el análisis espacial mediante el uso de la ligazón con plantilla de ARN
US12365942B2 (en) 2020-01-13 2025-07-22 10X Genomics, Inc. Methods of decreasing background on a spatial array
US11649497B2 (en) 2020-01-13 2023-05-16 Becton, Dickinson And Company Methods and compositions for quantitation of proteins and RNA
US12405264B2 (en) 2020-01-17 2025-09-02 10X Genomics, Inc. Electrophoretic system and method for analyte capture
US11702693B2 (en) 2020-01-21 2023-07-18 10X Genomics, Inc. Methods for printing cells and generating arrays of barcoded cells
US11732299B2 (en) 2020-01-21 2023-08-22 10X Genomics, Inc. Spatial assays with perturbed cells
US20210230681A1 (en) 2020-01-24 2021-07-29 10X Genomics, Inc. Methods for spatial analysis using proximity ligation
WO2021155057A1 (en) 2020-01-29 2021-08-05 Becton, Dickinson And Company Barcoded wells for spatial mapping of single cells through sequencing
US11821035B1 (en) 2020-01-29 2023-11-21 10X Genomics, Inc. Compositions and methods of making gene expression libraries
US12076701B2 (en) 2020-01-31 2024-09-03 10X Genomics, Inc. Capturing oligonucleotides in spatial transcriptomics
US11898205B2 (en) 2020-02-03 2024-02-13 10X Genomics, Inc. Increasing capture efficiency of spatial assays
US12110541B2 (en) 2020-02-03 2024-10-08 10X Genomics, Inc. Methods for preparing high-resolution spatial arrays
US11732300B2 (en) 2020-02-05 2023-08-22 10X Genomics, Inc. Increasing efficiency of spatial analysis in a biological sample
WO2021158925A1 (en) 2020-02-07 2021-08-12 10X Genomics, Inc. Quantitative and automated permeabilization performance evaluation for spatial transcriptomics
US12281357B1 (en) 2020-02-14 2025-04-22 10X Genomics, Inc. In situ spatial barcoding
US12399123B1 (en) 2020-02-14 2025-08-26 10X Genomics, Inc. Spatial targeting of analytes
US11891654B2 (en) 2020-02-24 2024-02-06 10X Genomics, Inc. Methods of making gene expression libraries
WO2021173719A1 (en) 2020-02-25 2021-09-02 Becton, Dickinson And Company Bi-specific probes to enable the use of single-cell samples as single color compensation control
US11768175B1 (en) 2020-03-04 2023-09-26 10X Genomics, Inc. Electrophoretic methods for spatial analysis
ES2965354T3 (es) 2020-04-22 2024-04-12 10X Genomics Inc Métodos para análisis espacial que usan eliminación de ARN elegido como diana
EP4150118A1 (en) 2020-05-14 2023-03-22 Becton Dickinson and Company Primers for immune repertoire profiling
US12416603B2 (en) 2020-05-19 2025-09-16 10X Genomics, Inc. Electrophoresis cassettes and instrumentation
WO2021237087A1 (en) 2020-05-22 2021-11-25 10X Genomics, Inc. Spatial analysis to detect sequence variants
WO2021236929A1 (en) 2020-05-22 2021-11-25 10X Genomics, Inc. Simultaneous spatio-temporal measurement of gene expression and cellular activity
WO2021242834A1 (en) 2020-05-26 2021-12-02 10X Genomics, Inc. Method for resetting an array
EP4158055B1 (en) 2020-06-02 2024-03-27 Becton, Dickinson and Company Oligonucleotides and beads for 5 prime gene expression assay
EP4600376A3 (en) 2020-06-02 2025-10-22 10X Genomics, Inc. Spatial transcriptomics for antigen-receptors
US12265079B1 (en) 2020-06-02 2025-04-01 10X Genomics, Inc. Systems and methods for detecting analytes from captured single biological particles
US12031177B1 (en) 2020-06-04 2024-07-09 10X Genomics, Inc. Methods of enhancing spatial resolution of transcripts
EP4421186B1 (en) 2020-06-08 2025-08-13 10X Genomics, Inc. Methods of determining a surgical margin and methods of use thereof
ES2999535T3 (en) 2020-06-10 2025-02-26 10X Genomics Inc Methods for determining a location of an analyte in a biological sample
US12435363B1 (en) 2020-06-10 2025-10-07 10X Genomics, Inc. Materials and methods for spatial transcriptomics
WO2021262422A1 (en) * 2020-06-25 2021-12-30 Huang Chung Ying Method and system of dna and rna detection
WO2021263111A1 (en) 2020-06-25 2021-12-30 10X Genomics, Inc. Spatial analysis of dna methylation
US11761038B1 (en) 2020-07-06 2023-09-19 10X Genomics, Inc. Methods for identifying a location of an RNA in a biological sample
US11981960B1 (en) 2020-07-06 2024-05-14 10X Genomics, Inc. Spatial analysis utilizing degradable hydrogels
US12209280B1 (en) 2020-07-06 2025-01-28 10X Genomics, Inc. Methods of identifying abundance and location of an analyte in a biological sample using second strand synthesis
US11932901B2 (en) 2020-07-13 2024-03-19 Becton, Dickinson And Company Target enrichment using nucleic acid probes for scRNAseq
WO2022026909A1 (en) 2020-07-31 2022-02-03 Becton, Dickinson And Company Single cell assay for transposase-accessible chromatin
US11981958B1 (en) 2020-08-20 2024-05-14 10X Genomics, Inc. Methods for spatial analysis using DNA capture
ES2993269T3 (en) 2020-09-18 2024-12-26 10X Genomics Inc Sample handling apparatus and image registration methods
US11926822B1 (en) 2020-09-23 2024-03-12 10X Genomics, Inc. Three-dimensional spatial analysis
US11827935B1 (en) 2020-11-19 2023-11-28 10X Genomics, Inc. Methods for spatial analysis using rolling circle amplification and detection probes
US11739443B2 (en) 2020-11-20 2023-08-29 Becton, Dickinson And Company Profiling of highly expressed and lowly expressed proteins
US12392771B2 (en) 2020-12-15 2025-08-19 Becton, Dickinson And Company Single cell secretome analysis
AU2021409136A1 (en) 2020-12-21 2023-06-29 10X Genomics, Inc. Methods, compositions, and systems for capturing probes and/or barcodes
EP4421491A3 (en) 2021-02-19 2024-11-27 10X Genomics, Inc. Method of using a modular assay support device
EP4524261A3 (en) 2021-03-18 2025-05-14 10X Genomics, Inc. Multiplex capture of gene and protein expression from a biological sample
EP4305196B1 (en) 2021-04-14 2025-04-02 10X Genomics, Inc. Methods of measuring mislocalization of an analyte
EP4320271B1 (en) 2021-05-06 2025-03-19 10X Genomics, Inc. Methods for increasing resolution of spatial analysis
ES3030033T3 (en) 2021-06-03 2025-06-26 10X Genomics Inc Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis
ES3011462T3 (en) 2021-09-01 2025-04-07 10X Genomics Inc Methods for blocking a capture probe on a spatial array
WO2023086880A1 (en) 2021-11-10 2023-05-19 10X Genomics, Inc. Methods, compositions, and kits for determining the location of an analyte in a biological sample
WO2023102118A2 (en) 2021-12-01 2023-06-08 10X Genomics, Inc. Methods, compositions, and systems for improved in situ detection of analytes and spatial analysis
EP4441711A1 (en) 2021-12-20 2024-10-09 10X Genomics, Inc. Self-test for pathology/histology slide imaging device

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4353888A (en) * 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
EP0773294A3 (en) * 1989-07-28 1997-09-17 Us Health Powerful system for targeted genetic cloning
US5545522A (en) * 1989-09-22 1996-08-13 Van Gelder; Russell N. Process for amplifying a target polynucleotide sequence using a single primer-promoter complex
CA2114950A1 (en) * 1991-08-10 1993-02-11 Michael J. Embleton Treatment of cell populations
US5807522A (en) * 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US5882856A (en) * 1995-06-07 1999-03-16 Genzyme Corporation Universal primer sequence for multiplex DNA amplification
US5962271A (en) * 1996-01-03 1999-10-05 Cloutech Laboratories, Inc. Methods and compositions for generating full-length cDNA having arbitrary nucleotide sequence at the 3'-end
AU2253397A (en) 1996-01-23 1997-08-20 Affymetrix, Inc. Nucleic acid analysis techniques
US5935793A (en) * 1996-09-27 1999-08-10 The Chinese University Of Hong Kong Parallel polynucleotide sequencing method using tagged primers
JP2001511361A (ja) * 1997-07-22 2001-08-14 ラピジーン,インコーポレイテッド 核酸アレイ上で行われる増幅および他の酵素反応
US7214298B2 (en) * 1997-09-23 2007-05-08 California Institute Of Technology Microfabricated cell sorter
US6232066B1 (en) * 1997-12-19 2001-05-15 Neogen, Inc. High throughput assay system
US6238869B1 (en) * 1997-12-19 2001-05-29 High Throughput Genomics, Inc. High throughput assay system
US6087102A (en) * 1998-01-07 2000-07-11 Clontech Laboratories, Inc. Polymeric arrays and methods for their use in binding assays
US6562567B2 (en) * 1998-01-27 2003-05-13 California Institute Of Technology Method of detecting a nucleic acid
US6500938B1 (en) * 1998-01-30 2002-12-31 Incyte Genomics, Inc. Composition for the detection of signaling pathway gene expression
US6287765B1 (en) * 1998-05-20 2001-09-11 Molecular Machines, Inc. Methods for detecting and identifying single molecules
AU754952B2 (en) * 1998-06-24 2002-11-28 Illumina, Inc. Decoding of array sensors with microspheres
US6458566B2 (en) * 1998-10-23 2002-10-01 Albert Einstein College Of Medicine Of Yeshiva University Method of identification of differentially expressed MRNA
US6258536B1 (en) * 1998-12-01 2001-07-10 Jonathan Oliner Expression monitoring of downstream genes in the BRCA1 pathway
US6531302B1 (en) * 1999-04-12 2003-03-11 Nanogen/Becton Dickinson Partnership Anchored strand displacement amplification on an electronically addressable microchip
US6495320B1 (en) * 1999-07-21 2002-12-17 Affymetrix, Inc. Even length proportional amplification of nucleic acids
PT1218542E (pt) * 1999-09-13 2004-08-31 Nugen Technologies Inc Metodos e composicoes para amplificacao isotermica linear de sequencias polinucleotidicas
US6607885B1 (en) * 1999-10-15 2003-08-19 E. I. Du Pont De Nemours And Company Method for high-density microarray medicated gene expression profiling
US6406840B1 (en) * 1999-12-17 2002-06-18 Biomosaic Systems, Inc. Cell arrays and the uses thereof
WO2001048242A2 (en) * 1999-12-29 2001-07-05 Mergen Ltd. Methods for amplifying and detecting multiple polynucleotides on a solid phase support
CA2398107C (en) 2000-01-28 2013-11-19 Althea Technologies, Inc. Methods for analysis of gene expression
US6235483B1 (en) * 2000-01-31 2001-05-22 Agilent Technologies, Inc. Methods and kits for indirect labeling of nucleic acids
DE60136166D1 (de) * 2000-02-07 2008-11-27 Illumina Inc Nukleinsäure-nachweisverfahren mit universellem priming
US20010026919A1 (en) * 2000-02-08 2001-10-04 Alex Chenchik Nucleic acid assays employing universal arrays
AU2001247328C1 (en) * 2000-03-08 2006-10-26 Datascope Investment Corp. Methods for assay and detection on a microarray
US20020164594A1 (en) 2000-03-17 2002-11-07 Monforte Joseph A. Systematic approach to the analysis of gene function
WO2002008466A1 (en) 2000-07-21 2002-01-31 Althea Technologies, Inc. A systematic approach to mechanism-of-response analyses
US7294503B2 (en) * 2000-09-15 2007-11-13 California Institute Of Technology Microfabricated crossflow devices and methods
US7198895B2 (en) 2000-11-14 2007-04-03 Mohanlal Ramon W In vitro cell-based methods for biological validation and pharmacological screening of chemical entities and biologicals
WO2002090599A1 (en) * 2001-05-09 2002-11-14 Genetic Id, Inc. Universal microarray system
CA2450139A1 (en) * 2001-06-11 2002-12-19 Illumina, Inc Multiplexed detection methods
US7476519B2 (en) * 2002-07-19 2009-01-13 Joseph Monforte Strategies for gene expression analysis
US20050073410A1 (en) * 2003-09-23 2005-04-07 Benson Chiang Two-piece adjustable auto-search alarm device

Also Published As

Publication number Publication date
SG149007A1 (en) 2009-01-29
EP1660674A2 (en) 2006-05-31
EP1660674A4 (en) 2008-05-14
WO2005042759A3 (en) 2006-04-13
JP5171037B2 (ja) 2013-03-27
JP2007504831A (ja) 2007-03-08
EP1660674B1 (en) 2010-03-17
ATE461292T1 (de) 2010-04-15
AU2004286201B2 (en) 2010-09-09
CA2536565A1 (en) 2005-05-12
US7824856B2 (en) 2010-11-02
AU2004286201A1 (en) 2005-05-12
WO2005042759A2 (en) 2005-05-12
US20110092387A1 (en) 2011-04-21
US20050170373A1 (en) 2005-08-04

Similar Documents

Publication Publication Date Title
DE602004026077D1 (de) Erstellung von expressionsprofilen unter verwendung von mikroarrays
EP3737773B1 (en) Novel primers and uses thereof
ATE361996T1 (de) Methoden und zusammensetzungen zur vervielfältigung von rna sequenzen
ATE534748T1 (de) Direkter snp-nachweis mit nichtamplifizierter dna
WO2000077260A8 (en) Genomic profiling: a rapid method for testing a complex biological sample for the presence of many types of organisms
ATE358733T1 (de) Schnell-verfahren zur detektion von mikroorganismen in lebensmittelproben
WO2008014485A3 (en) Multiplex q-pcr arrays
SE0301951D0 (sv) New method
JP2006512081A (ja) Rnaのローリングサークル増幅
Sabeeha et al. Forensic epigenetic analysis: the path ahead
IS6206A (is) Aðferð til hlutfallslegrar skömmtunar á metýleringu á bösum af sýtósín-gerð í DNA sýnum
DE60143314D1 (de) Estimmung der präsenz von cryptosporidium organismen in einer testprobe
Miyata et al. Bisulfite sequencing for DNA methylation analysis of primary muscle stem cells
ATE546550T1 (de) Verfahren zum nachweis von hpv sowie sonden, primer und kits
Sharma et al. Using single cell analysis for translational studies in immune mediated diseases: opportunities and challenges
EP1480155A3 (en) Information processing apparatus, information processing method, storage medium and program
DE59914661D1 (de) Zwei farben differential display als verfahren zur detektion regulierter gene
Fox et al. Comparison of reverse transcription–quantitative polymerase chain reaction methods and platforms for single cell gene expression analysis
DE60306865D1 (de) Detektion von Vancomycin-resistenten Enterococcus-Subspezies
Holland Molecular analysis of the human mitochondrial DNA control region for forensic identity testing
US9994893B2 (en) Compositions and methods for functional quality control for human blood-based gene expression products
KR101398548B1 (ko) 저급 지방족 포화 알데하이드류 특이적 노출 여부 확인용 바이오마커 및 이를 이용한 확인 방법
Lee et al. Applying a linear amplification strategy to recombinase polymerase amplification for uniform DNA library amplification
WO2005017488A3 (en) Method and system for identifying biological entities in biological and environmental samples
EP1323835A3 (en) Method for determining biospecies contained in test specimen and kit used for the same

Legal Events

Date Code Title Description
8364 No opposition during term of opposition