US4027971A
(en)
|
1973-01-08 |
1977-06-07 |
Philip Kolman |
Method of simultaneously counting blood cells
|
US4469863A
(en)
|
1980-11-12 |
1984-09-04 |
Ts O Paul O P |
Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof
|
US4711955A
(en)
*
|
1981-04-17 |
1987-12-08 |
Yale University |
Modified nucleotides and methods of preparing and using same
|
US4994373A
(en)
*
|
1983-01-27 |
1991-02-19 |
Enzo Biochem, Inc. |
Method and structures employing chemically-labelled polynucleotide probes
|
GB8314523D0
(en)
*
|
1983-05-25 |
1983-06-29 |
Lowe C R |
Diagnostic device
|
US4539295A
(en)
|
1983-06-30 |
1985-09-03 |
Beckman Instruments, Inc. |
Binary kinetic assay method and apparatus
|
US5235033A
(en)
|
1985-03-15 |
1993-08-10 |
Anti-Gene Development Group |
Alpha-morpholino ribonucleoside derivatives and polymers thereof
|
US5034506A
(en)
|
1985-03-15 |
1991-07-23 |
Anti-Gene Development Group |
Uncharged morpholino-based polymers having achiral intersubunit linkages
|
US5333675C1
(en)
*
|
1986-02-25 |
2001-05-01 |
Perkin Elmer Corp |
Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
US4683195A
(en)
|
1986-01-30 |
1987-07-28 |
Cetus Corporation |
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
|
US5656493A
(en)
*
|
1985-03-28 |
1997-08-12 |
The Perkin-Elmer Corporation |
System for automated performance of the polymerase chain reaction
|
CA1339653C
(en)
|
1986-02-25 |
1998-02-03 |
Larry J. Johnson |
Appartus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
|
US5322770A
(en)
|
1989-12-22 |
1994-06-21 |
Hoffman-Laroche Inc. |
Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription
|
US5618711A
(en)
|
1986-08-22 |
1997-04-08 |
Hoffmann-La Roche Inc. |
Recombinant expression vectors and purification methods for Thermus thermophilus DNA polymerase
|
US5407800A
(en)
|
1986-08-22 |
1995-04-18 |
Hoffmann-La Roche Inc. |
Reverse transcription with Thermus thermophilus polymerase
|
US6127155A
(en)
|
1986-08-22 |
2000-10-03 |
Roche Molecular Systems, Inc. |
Stabilized thermostable nucleic acid polymerase compositions containing non-ionic polymeric detergents
|
US5310652A
(en)
|
1986-08-22 |
1994-05-10 |
Hoffman-La Roche Inc. |
Reverse transcription with thermostable DNA polymerase-high temperature reverse transcription
|
CA1340807C
(en)
|
1988-02-24 |
1999-11-02 |
Lawrence T. Malek |
Nucleic acid amplification process
|
US5082830A
(en)
*
|
1988-02-26 |
1992-01-21 |
Enzo Biochem, Inc. |
End labeled nucleotide probe
|
US6054270A
(en)
*
|
1988-05-03 |
2000-04-25 |
Oxford Gene Technology Limited |
Analying polynucleotide sequences
|
US5216141A
(en)
|
1988-06-06 |
1993-06-01 |
Benner Steven A |
Oligonucleotide analogs containing sulfur linkages
|
US5130238A
(en)
|
1988-06-24 |
1992-07-14 |
Cangene Corporation |
Enhanced nucleic acid amplification process
|
US6551784B2
(en)
|
1989-06-07 |
2003-04-22 |
Affymetrix Inc |
Method of comparing nucleic acid sequences
|
US5744101A
(en)
*
|
1989-06-07 |
1998-04-28 |
Affymax Technologies N.V. |
Photolabile nucleoside protecting groups
|
US5143854A
(en)
*
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
US5800992A
(en)
*
|
1989-06-07 |
1998-09-01 |
Fodor; Stephen P.A. |
Method of detecting nucleic acids
|
US5871928A
(en)
*
|
1989-06-07 |
1999-02-16 |
Fodor; Stephen P. A. |
Methods for nucleic acid analysis
|
CA2020958C
(en)
|
1989-07-11 |
2005-01-11 |
Daniel L. Kacian |
Nucleic acid sequence amplification methods
|
EP0731175A3
(en)
|
1989-07-11 |
2004-05-26 |
Gen-Probe Incorporated |
Oligonucleotide probes for HIV nucleic acid
|
US5386023A
(en)
|
1990-07-27 |
1995-01-31 |
Isis Pharmaceuticals |
Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
|
US5602240A
(en)
|
1990-07-27 |
1997-02-11 |
Ciba Geigy Ag. |
Backbone modified oligonucleotide analogs
|
US5210015A
(en)
|
1990-08-06 |
1993-05-11 |
Hoffman-La Roche Inc. |
Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
|
KR100236506B1
(en)
*
|
1990-11-29 |
2000-01-15 |
퍼킨-엘머시터스인스트루먼츠 |
Apparatus for polymerase chain reaction
|
US5455166A
(en)
|
1991-01-31 |
1995-10-03 |
Becton, Dickinson And Company |
Strand displacement amplification
|
US5994056A
(en)
|
1991-05-02 |
1999-11-30 |
Roche Molecular Systems, Inc. |
Homogeneous methods for nucleic acid amplification and detection
|
WO1993008464A1
(en)
|
1991-10-21 |
1993-04-29 |
Holm Kennedy James W |
Method and device for biochemical sensing
|
US6048690A
(en)
*
|
1991-11-07 |
2000-04-11 |
Nanogen, Inc. |
Methods for electronic fluorescent perturbation for analysis and electronic perturbation catalysis for synthesis
|
US5632957A
(en)
*
|
1993-11-01 |
1997-05-27 |
Nanogen |
Molecular biological diagnostic systems including electrodes
|
US5270184A
(en)
|
1991-11-19 |
1993-12-14 |
Becton, Dickinson And Company |
Nucleic acid target generation
|
DE69233331T3
(en)
*
|
1991-11-22 |
2007-08-30 |
Affymetrix, Inc., Santa Clara |
Combinatorial Polymersynthesis Strategies
|
US5644048A
(en)
|
1992-01-10 |
1997-07-01 |
Isis Pharmaceuticals, Inc. |
Process for preparing phosphorothioate oligonucleotides
|
EP0566751B1
(en)
*
|
1992-03-23 |
1996-01-10 |
F. Hoffmann-La Roche Ag |
DNA detection method
|
US5323115A
(en)
|
1992-05-05 |
1994-06-21 |
Xerox Corporation |
Electrostatic voltmeter producing a low voltage output
|
US5674698A
(en)
|
1992-09-14 |
1997-10-07 |
Sri International |
Up-converting reporters for biological and other assays using laser excitation techniques
|
US5837501A
(en)
|
1993-07-09 |
1998-11-17 |
Akzo Nobel N.V. |
Nucleic acid quantitation by co-amplification of target with multiple internal controls
|
US5965452A
(en)
*
|
1996-07-09 |
1999-10-12 |
Nanogen, Inc. |
Multiplexed active biologic array
|
US5925517A
(en)
|
1993-11-12 |
1999-07-20 |
The Public Health Research Institute Of The City Of New York, Inc. |
Detectably labeled dual conformation oligonucleotide probes, assays and kits
|
US5538848A
(en)
|
1994-11-16 |
1996-07-23 |
Applied Biosystems Division, Perkin-Elmer Corp. |
Method for detecting nucleic acid amplification using self-quenching fluorescence probe
|
US5578832A
(en)
*
|
1994-09-02 |
1996-11-26 |
Affymetrix, Inc. |
Method and apparatus for imaging a sample on a device
|
US5637684A
(en)
|
1994-02-23 |
1997-06-10 |
Isis Pharmaceuticals, Inc. |
Phosphoramidate and phosphorothioamidate oligomeric compounds
|
US5455705A
(en)
|
1994-03-14 |
1995-10-03 |
Analog Devices, Inc. |
Transimpedance amplifier for optical receiver
|
US5648211A
(en)
|
1994-04-18 |
1997-07-15 |
Becton, Dickinson And Company |
Strand displacement amplification using thermophilic enzymes
|
US5807522A
(en)
*
|
1994-06-17 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for fabricating microarrays of biological samples
|
US6379897B1
(en)
*
|
2000-11-09 |
2002-04-30 |
Nanogen, Inc. |
Methods for gene expression monitoring on electronic microarrays
|
US5491063A
(en)
*
|
1994-09-01 |
1996-02-13 |
Hoffmann-La Roche Inc. |
Methods for in-solution quenching of fluorescently labeled oligonucleotide probes
|
US5599668A
(en)
|
1994-09-22 |
1997-02-04 |
Abbott Laboratories |
Light scattering optical waveguide method for detecting specific binding events
|
US5795716A
(en)
*
|
1994-10-21 |
1998-08-18 |
Chee; Mark S. |
Computer-aided visualization and analysis system for sequence evaluation
|
US6600996B2
(en)
*
|
1994-10-21 |
2003-07-29 |
Affymetrix, Inc. |
Computer-aided techniques for analyzing biological sequences
|
US5571673A
(en)
*
|
1994-11-23 |
1996-11-05 |
Hoffmann-La Roche Inc. |
Methods for in-solution quenching of fluorescently labeled oligonucleotide probes
|
US6153425A
(en)
|
1995-07-13 |
2000-11-28 |
Xtrana, Inc. |
Self-contained device integrating nucleic acid extraction, amplification and detection
|
WO1997003348A1
(en)
|
1995-07-13 |
1997-01-30 |
Immunological Associates Of Denver |
Self-contained device integrating nucleic acid extraction, amplification and detection
|
US5773258A
(en)
|
1995-08-25 |
1998-06-30 |
Roche Molecular Systems, Inc. |
Nucleic acid amplification using a reversibly inactivated thermostable enzyme
|
US5854033A
(en)
|
1995-11-21 |
1998-12-29 |
Yale University |
Rolling circle replication reporter systems
|
US6852487B1
(en)
|
1996-02-09 |
2005-02-08 |
Cornell Research Foundation, Inc. |
Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
|
WO1997032212A1
(en)
|
1996-03-01 |
1997-09-04 |
Beckman Instruments, Inc. |
System for simultaneously conducting multiple ligand binding assays
|
US6114122A
(en)
|
1996-03-26 |
2000-09-05 |
Affymetrix, Inc. |
Fluidics station with a mounting system and method of using
|
US5627054A
(en)
|
1996-04-05 |
1997-05-06 |
The United States Of America As Represented By The Secretary Of The Army |
Competitor primer asymmetric polymerase chain reaction
|
US5981956A
(en)
|
1996-05-16 |
1999-11-09 |
Affymetrix, Inc. |
Systems and methods for detection of labeled materials
|
US5925519A
(en)
|
1996-06-03 |
1999-07-20 |
The Regents Of The University Of California |
Genetic alterations associated with prostate cancer
|
AU3477397A
(en)
|
1996-06-04 |
1998-01-05 |
Paul J. Werbos |
3-brain architecture for an intelligent decision and control system
|
ATE428801T1
(en)
*
|
1996-06-04 |
2009-05-15 |
Univ Utah Res Found |
MONITORING HYBRIDIZATION DURING PCR
|
US6984491B2
(en)
|
1996-07-29 |
2006-01-10 |
Nanosphere, Inc. |
Nanoparticles having oligonucleotides attached thereto and uses therefor
|
US6391550B1
(en)
|
1996-09-19 |
2002-05-21 |
Affymetrix, Inc. |
Identification of molecular sequence signatures and methods involving the same
|
WO1998029736A1
(en)
|
1996-12-31 |
1998-07-09 |
Genometrix Incorporated |
Multiplexed molecular analysis apparatus and method
|
CN100434531C
(en)
|
1997-01-15 |
2008-11-19 |
X齐里昂有限两合公司 |
Mass label linked hybridisation probes
|
US6327410B1
(en)
|
1997-03-14 |
2001-12-04 |
The Trustees Of Tufts College |
Target analyte sensors utilizing Microspheres
|
US7622294B2
(en)
|
1997-03-14 |
2009-11-24 |
Trustees Of Tufts College |
Methods for detecting target analytes and enzymatic reactions
|
EP1003908B1
(en)
|
1997-04-16 |
2006-12-06 |
Applera Corporation |
Nucleic acid archiving
|
US6872527B2
(en)
|
1997-04-16 |
2005-03-29 |
Xtrana, Inc. |
Nucleic acid archiving
|
US5846726A
(en)
|
1997-05-13 |
1998-12-08 |
Becton, Dickinson And Company |
Detection of nucleic acids by fluorescence quenching
|
CA2291180A1
(en)
|
1997-05-23 |
1998-11-26 |
Lynx Therapeutics, Inc. |
System and apparatus for sequential processing of analytes
|
US6969488B2
(en)
|
1998-05-22 |
2005-11-29 |
Solexa, Inc. |
System and apparatus for sequential processing of analytes
|
WO1999011813A2
(en)
*
|
1997-09-04 |
1999-03-11 |
Bayer Corporation |
Oligonucleotide probes bearing quenchable fluorescent labels, and methods of use thereof
|
US20010046673A1
(en)
|
1999-03-16 |
2001-11-29 |
Ljl Biosystems, Inc. |
Methods and apparatus for detecting nucleic acid polymorphisms
|
CA2325886C
(en)
|
1998-04-09 |
2009-07-21 |
California Institute Of Technology |
Electronic techniques for analyte detection
|
US6330092B1
(en)
|
1998-05-08 |
2001-12-11 |
Agilent Technologies, Inc. |
Polarization based differential receiver for reduction of background in free-space optical links
|
US6319958B1
(en)
*
|
1998-06-22 |
2001-11-20 |
Wisconsin Alumni Research Foundation |
Method of sensitizing microbial cells to antimicrobial compound
|
ATE423314T1
(en)
|
1998-06-24 |
2009-03-15 |
Illumina Inc |
DECODING OF MATRIXED SENSORS BY MICROPARTICLES
|
EP2287338B1
(en)
|
1998-11-09 |
2012-09-05 |
Eiken Kagaku Kabushiki Kaisha |
Process for synthesizing nucleic acid
|
AU2965500A
(en)
|
1999-01-15 |
2000-08-01 |
Gene Logic, Inc. |
Immobilized nucleic acid hybridization reagent and method
|
GB9901475D0
(en)
|
1999-01-22 |
1999-03-17 |
Pyrosequencing Ab |
A method of DNA sequencing
|
EP1151139A2
(en)
|
1999-01-25 |
2001-11-07 |
UT-Battelle, LLC |
Multifunctional and multispectral biosensor devices and methods of use
|
CA2359637A1
(en)
|
1999-01-26 |
2000-07-27 |
Stephen F. Fulghum, Jr. |
Autofluorescence imaging system for endoscopy
|
US7107253B1
(en)
|
1999-04-05 |
2006-09-12 |
American Board Of Family Practice, Inc. |
Computer architecture and process of patient generation, evolution and simulation for computer based testing system using bayesian networks as a scripting language
|
US7423750B2
(en)
|
2001-11-29 |
2008-09-09 |
Applera Corporation |
Configurations, systems, and methods for optical scanning with at least one first relative angular motion and at least one second angular motion or at least one linear motion
|
US6277607B1
(en)
|
1999-05-24 |
2001-08-21 |
Sanjay Tyagi |
High specificity primers, amplification methods and kits
|
US6516276B1
(en)
|
1999-06-18 |
2003-02-04 |
Eos Biotechnology, Inc. |
Method and apparatus for analysis of data from biomolecular arrays
|
AU5882000A
(en)
|
1999-06-22 |
2001-01-09 |
Invitrogen Corporation |
Improved primers and methods for the detection and discrimination of nucleic acids
|
CN102586228A
(en)
|
1999-09-13 |
2012-07-18 |
纽亘技术公司 |
Methods and composition for linear isothermal amplification of polynucleotide sequences
|
AU7708500A
(en)
|
1999-09-22 |
2001-04-24 |
Ge Healthcare Bio-Sciences Ab |
Three-dimensional microarray system for parallel genotyping of single nucleotide polymorphisms
|
US6673536B1
(en)
|
1999-09-29 |
2004-01-06 |
Rosetta Inpharmatics Llc. |
Methods of ranking oligonucleotides for specificity using wash dissociation histories
|
US6784982B1
(en)
|
1999-11-04 |
2004-08-31 |
Regents Of The University Of Minnesota |
Direct mapping of DNA chips to detector arrays
|
US6428957B1
(en)
|
1999-11-08 |
2002-08-06 |
Agilent Technologies, Inc. |
Systems tools and methods of assaying biological materials using spatially-addressable arrays
|
DE10002566A1
(en)
|
2000-01-21 |
2001-08-02 |
Fraunhofer Ges Forschung |
Method and device for determining the melting point and / or the binding constant of substances such. B. DNA sequences in a sample
|
US7033763B2
(en)
|
2000-02-23 |
2006-04-25 |
City Of Hope |
Pyrophosphorolysis activated polymerization (PAP)
|
US20020006619A1
(en)
*
|
2000-02-23 |
2002-01-17 |
David Cohen |
Thermal cycler that allows two-dimension temperature gradients and hold time optimization
|
US6579680B2
(en)
|
2000-02-28 |
2003-06-17 |
Corning Incorporated |
Method for label-free detection of hybridized DNA targets
|
WO2006053770A1
(en)
|
2004-11-18 |
2006-05-26 |
Eppendorf Array Technologies |
Real-time pcr of targets on a micro-array
|
US7205104B2
(en)
|
2000-03-24 |
2007-04-17 |
Eppendorf Array Technologies Sa (Eat) |
Identification of biological (micro) organisms by detection of their homologous nucleotide sequences on arrays
|
US7998673B2
(en)
|
2000-03-29 |
2011-08-16 |
Lgc Limited |
Hybridisation beacon and method of rapid sequence detection and discrimination
|
ATE334228T1
(en)
|
2000-03-29 |
2006-08-15 |
Lgc Ltd |
HYBRIDIZATION SAMPLE AND METHOD FOR RAPID DETECTION AND DISCRIMINATION OF SEQUENCES
|
US6783934B1
(en)
|
2000-05-01 |
2004-08-31 |
Cepheid, Inc. |
Methods for quantitative analysis of nucleic acid amplification reaction
|
AU6114501A
(en)
|
2000-05-03 |
2001-11-12 |
Jen Gau Jr |
Biological identification system with integrated sensor chip
|
US7019129B1
(en)
|
2000-05-09 |
2006-03-28 |
Biosearch Technologies, Inc. |
Dark quenchers for donor-acceptor energy transfer
|
DE60140804D1
(en)
|
2000-06-27 |
2010-01-28 |
Nat Inst Of Advanced Ind Scien |
NEW NUCLEIC ACID EASTS AND METHOD FOR TESTING NUCLEIC ACIDS UNDER USE
|
US6472887B1
(en)
|
2000-06-28 |
2002-10-29 |
Hewlett-Packard Company |
Capacitive sensor for sensing the amount of material in a container
|
DE10036457A1
(en)
*
|
2000-07-26 |
2002-02-14 |
Giesing Michael |
Use of an imaging photoelectric area sensor for evaluating biochips and imaging processes therefor
|
AU2001280889A1
(en)
|
2000-07-31 |
2002-02-13 |
Gene Logic, Inc. |
Molecular toxicology modeling
|
US20040005582A1
(en)
|
2000-08-10 |
2004-01-08 |
Nanobiodynamics, Incorporated |
Biospecific desorption microflow systems and methods for studying biospecific interactions and their modulators
|
WO2002014462A1
(en)
|
2000-08-14 |
2002-02-21 |
The Regents Of The University Of California |
Biosensors and methods for their use
|
US6724324B1
(en)
|
2000-08-21 |
2004-04-20 |
Delphi Technologies, Inc. |
Capacitive proximity sensor
|
US6469524B1
(en)
|
2000-08-25 |
2002-10-22 |
Delphi Technologies, Inc. |
System and method for interrogating a capacitive sensor
|
CN1348096A
(en)
|
2000-10-10 |
2002-05-08 |
栾国彦 |
Homogeneous specific nucleic acid detecting probe and its application method
|
AU2002241803A1
(en)
|
2000-10-20 |
2002-06-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Transient electrical signal based methods and devices for characterizing molecular interaction and/or motion in a sample
|
EP1203945B1
(en)
|
2000-10-26 |
2006-12-20 |
Agilent Technologies, Inc. (a Delaware corporation) |
Microarray
|
US6818427B1
(en)
|
2000-10-27 |
2004-11-16 |
Millennium Pharmaceuticals, Inc. |
MEKK1 molecules and uses thereof
|
US7892495B2
(en)
|
2000-11-08 |
2011-02-22 |
Huebner Jay S |
Sensing device and method for rapidly determining concentrations of microbial organisms using interfacial photo-voltages
|
US8900811B2
(en)
|
2000-11-16 |
2014-12-02 |
Caliper Life Sciences, Inc. |
Method and apparatus for generating thermal melting curves in a microfluidic device
|
US20050202470A1
(en)
|
2000-11-16 |
2005-09-15 |
Caliper Life Sciences, Inc. |
Binding assays using molecular melt curves
|
US6432695B1
(en)
*
|
2001-02-16 |
2002-08-13 |
Institute Of Microelectronics |
Miniaturized thermal cycler
|
CA2439307A1
(en)
|
2001-02-23 |
2002-09-06 |
Genicon Sciences Corporation |
Methods for providing extended dynamic range in analyte assays
|
BR0205268A
(en)
|
2001-03-09 |
2004-11-30 |
Nugen Technologies Inc |
Processes and compositions for mRNA sequence mplification
|
GB0105831D0
(en)
|
2001-03-09 |
2001-04-25 |
Toumaz Technology Ltd |
Method for dna sequencing utilising enzyme linked field effect transistors
|
US20020146745A1
(en)
|
2001-04-03 |
2002-10-10 |
Surromed, Inc. |
Methods and reagents for multiplexed analyte capture, surface array self-assembly, and analysis of complex biological samples
|
CN1325658C
(en)
|
2001-04-23 |
2007-07-11 |
三星电子株式会社 |
Molecular detection chip including MOSFET, molecular detection device employing chip, and molecular detection method using the device
|
GB0111459D0
(en)
|
2001-05-10 |
2001-07-04 |
Isis Innovation |
Universal fluorescent sensors
|
US20020177157A1
(en)
|
2001-05-24 |
2002-11-28 |
Yuling Luo |
Pairs of nucleic acid probes with interactive signaling moieties and nucleic acid probes with enhanced hybridization efficiency and specificity
|
CA2452693A1
(en)
|
2001-06-06 |
2002-12-12 |
Digital Optical Imaging Corporation |
Light modulated microarray reader and methods relating thereto
|
US20020187477A1
(en)
|
2001-06-06 |
2002-12-12 |
Hong Xue |
Method for detecting single nucleotide polymorphisms (SNPs) and point mutations
|
EP1275735A1
(en)
|
2001-07-11 |
2003-01-15 |
Roche Diagnostics GmbH |
Composition and method for hot start nucleic acid amplification
|
US6403341B1
(en)
|
2001-08-02 |
2002-06-11 |
Wayne M. Barnes |
Magnesium precipitate hot start method for PCR
|
US20030040000A1
(en)
|
2001-08-08 |
2003-02-27 |
Connolly Dennis M. |
Methods for attaching nucleic acid molecules to electrically conductive surfaces
|
US7173032B2
(en)
|
2001-09-21 |
2007-02-06 |
Reddy Us Therapeutics, Inc. |
Methods and compositions of novel triazine compounds
|
US6593091B2
(en)
|
2001-09-24 |
2003-07-15 |
Beckman Coulter, Inc. |
Oligonucleotide probes for detecting nucleic acids through changes in flourescence resonance energy transfer
|
US6744502B2
(en)
|
2001-09-28 |
2004-06-01 |
Pe Corporation (Ny) |
Shaped illumination geometry and intensity using a diffractive optical element
|
US20070010664A1
(en)
*
|
2001-10-01 |
2007-01-11 |
Thomas Elizabeth A |
Gene expression in the central nervous system regulated by neuroleptic agents
|
KR20040068122A
(en)
|
2001-10-15 |
2004-07-30 |
바이오어레이 솔루션스 리미티드 |
Multiplexed analysis of polymorphic loci by concurrent interrogation and enzyme-mediated detection
|
US20030071843A1
(en)
|
2001-10-17 |
2003-04-17 |
Bruce Hoff |
System and method for specifying and applying microarray data preparation
|
WO2003043402A2
(en)
|
2001-10-19 |
2003-05-30 |
Proligo Llc |
Nucleic acid probes and methods to detect and/or quantify nucleic acid analytes
|
WO2003048310A2
(en)
|
2001-11-30 |
2003-06-12 |
Applera Corporation |
Thermus oshimai nucleic acid polymerases
|
US7198897B2
(en)
|
2001-12-19 |
2007-04-03 |
Brandeis University |
Late-PCR
|
WO2003062791A2
(en)
|
2002-01-18 |
2003-07-31 |
University Of Utah Research Foundation |
Detection of single nucleotide polymorphisms using planar waveguides
|
WO2003065244A1
(en)
|
2002-01-30 |
2003-08-07 |
Board Of Regents, The University Of Texas System |
Probabilistic boolean networks
|
US6953958B2
(en)
|
2002-03-19 |
2005-10-11 |
Cornell Research Foundation, Inc. |
Electronic gain cell based charge sensor
|
AU2003231058A1
(en)
|
2002-04-22 |
2003-11-03 |
Wisconsin Alumni Research Foundation |
Single nucleotide polymorphism analysis using surface invasive cleavage reactions
|
US7785776B2
(en)
|
2002-05-13 |
2010-08-31 |
Idaho Technology, Inc. |
Genotyping by amplicon melting curve analysis
|
US6750963B2
(en)
*
|
2002-05-21 |
2004-06-15 |
Agilent Technologies, Inc. |
Imaging systems for signals on a surface
|
JP3904111B2
(en)
|
2002-06-04 |
2007-04-11 |
ソニー株式会社 |
Solid-state imaging device and signal processing method thereof
|
WO2004011144A2
(en)
|
2002-07-29 |
2004-02-05 |
Dumas David P |
Transparent polymer support for electrophoresis and electrochromatography and related methods
|
US7267751B2
(en)
|
2002-08-20 |
2007-09-11 |
Nanogen, Inc. |
Programmable multiplexed active biologic array
|
US7282328B2
(en)
|
2002-09-20 |
2007-10-16 |
New England Biolabs, Inc. |
Helicase dependent amplification of nucleic acids
|
ES2237643T3
(en)
|
2002-10-21 |
2005-08-01 |
Axxam S.R.L. |
PHOTOPROTEIN WITH IMPROVED BIOLUMINISCENCE.
|
US20040086864A1
(en)
|
2002-10-22 |
2004-05-06 |
The Chinese University Of Hong Kong |
Novel classification methods for pleural effusions
|
CA2429101A1
(en)
|
2002-10-24 |
2004-04-24 |
Ben Gao |
Method and equipment to monitor nucleic acid hybridization on a dna chip using four-dimensional parameters
|
US20040147045A1
(en)
|
2002-10-29 |
2004-07-29 |
Gentel Biosurfaces, Inc. |
Signal molecule arrays
|
US7390457B2
(en)
*
|
2002-10-31 |
2008-06-24 |
Agilent Technologies, Inc. |
Integrated microfluidic array device
|
EP1416279B1
(en)
*
|
2002-10-31 |
2008-12-31 |
F. Hoffmann-La Roche Ag |
Methods for diagnosis of pancreatic cancer and composition useful therein
|
US20040121337A1
(en)
*
|
2002-12-19 |
2004-06-24 |
Nomadics, Inc. |
Luminescent polymers and methods of use thereof
|
US20060094108A1
(en)
|
2002-12-20 |
2006-05-04 |
Karl Yoder |
Thermal cycler for microfluidic array assays
|
EP1608952B1
(en)
|
2002-12-20 |
2016-08-10 |
Life Technologies Corporation |
Assay apparatus and method using microfluidic arrays
|
US20060014151A1
(en)
|
2002-12-25 |
2006-01-19 |
Jun Ogura |
Optical dna sensor, dna reading apparatus, identification method of dna and manufacturing method of optical dna sensor
|
ES2338654T5
(en)
|
2003-01-29 |
2017-12-11 |
454 Life Sciences Corporation |
Pearl emulsion nucleic acid amplification
|
US6859750B1
(en)
|
2003-02-13 |
2005-02-22 |
Agilent Technologies, Inc. |
Ramp sweep synthesis control
|
DE10315074A1
(en)
|
2003-04-02 |
2004-10-14 |
Clondiag Chip Technologies Gmbh |
Device for the duplication and detection of nucleic acids
|
ES2384170T3
(en)
*
|
2003-04-04 |
2012-07-02 |
F. Hoffmann-La Roche Ag |
Enhanced real-time multi-color PCR system
|
WO2004097371A2
(en)
|
2003-04-25 |
2004-11-11 |
Board Of Regents, The University Of Texas System |
System and method for the detection of analytes
|
US7741033B2
(en)
|
2003-05-13 |
2010-06-22 |
Trustees Of Boston College |
Electrocatalytic nucleic acid hybridization detection
|
US7554007B2
(en)
|
2003-05-22 |
2009-06-30 |
Evogene Ltd. |
Methods of increasing abiotic stress tolerance and/or biomass in plants
|
US7291496B2
(en)
|
2003-05-22 |
2007-11-06 |
University Of Hawaii |
Ultrasensitive biochemical sensor
|
US7633616B2
(en)
|
2003-06-02 |
2009-12-15 |
Sensovation Ag |
Apparatus and method for photo-electric measurement
|
WO2005029041A2
(en)
|
2003-09-19 |
2005-03-31 |
Applera Corporation |
High density sequence detection methods and apparatus
|
US7125945B2
(en)
|
2003-09-19 |
2006-10-24 |
Varian, Inc. |
Functionalized polymer for oligonucleotide purification
|
WO2005043160A2
(en)
|
2003-10-31 |
2005-05-12 |
University Of Hawaii |
Ultrasensitive biochemical sensing platform
|
US20050112585A1
(en)
|
2003-11-21 |
2005-05-26 |
Dominic Zichi |
Method for adjusting the quantification range of individual analytes in a multiplexed assay
|
US7462512B2
(en)
|
2004-01-12 |
2008-12-09 |
Polytechnic University |
Floating gate field effect transistors for chemical and/or biological sensing
|
US7485085B2
(en)
*
|
2004-01-23 |
2009-02-03 |
Applied Biosystems Inc. |
Heat transfer for thermal cycling
|
WO2005069737A2
(en)
*
|
2004-01-27 |
2005-08-04 |
Ramot At Tel Aviv University Ltd. |
Method and system for detecting analytes
|
EP1725683A2
(en)
*
|
2004-03-18 |
2006-11-29 |
Advandx, Inc |
Methods, kits and compositions pertaining to nucleic acid probes using fluorescence quenching
|
US7330369B2
(en)
|
2004-04-06 |
2008-02-12 |
Bao Tran |
NANO-electronic memory array
|
US7995679B2
(en)
|
2004-04-27 |
2011-08-09 |
Broadcom Corporation |
Method and system for charge sensing with variable gain, offset compensation, and demodulation
|
CA2567114A1
(en)
|
2004-05-28 |
2005-12-15 |
Nanogen, Inc. |
Nanoscale electronic detection system and methods for their manufacture
|
CN102680440A
(en)
|
2004-06-07 |
2012-09-19 |
先锋生物科技股份有限公司 |
Optical lens system and method for microfluidic devices
|
US7479557B2
(en)
|
2004-06-10 |
2009-01-20 |
Agency For Science, Technology +Research |
DNA threading intercalators
|
EP1774024A4
(en)
|
2004-07-02 |
2012-04-04 |
Blueshift Biotechnologies Inc |
Exploring fluorophore microenvironments
|
JP4794832B2
(en)
|
2004-07-02 |
2011-10-19 |
キヤノン株式会社 |
Nucleic acid detection probe set and carrier
|
GB2416210B
(en)
|
2004-07-13 |
2008-02-20 |
Christofer Toumazou |
Ion sensitive field effect transistors
|
US8517329B2
(en)
|
2004-07-26 |
2013-08-27 |
3M Innovative Properties Company |
Easel stand mountable display board
|
JP2006047153A
(en)
|
2004-08-05 |
2006-02-16 |
Sony Corp |
Manufacturing method and manufacturing system of dna chip, detection method and detection system of hybridization, and substrate processing device and substrate processing method
|
CN1280422C
(en)
|
2004-08-26 |
2006-10-18 |
北京博奥生物芯片有限责任公司 |
Asymmetrical PCR amplification method, dedicated primer and use thereof
|
US7888013B2
(en)
|
2004-08-27 |
2011-02-15 |
National Institute For Materials Science |
Method of analyzing DNA sequence using field-effect device, and base sequence analyzer
|
US20070212681A1
(en)
|
2004-08-30 |
2007-09-13 |
Benjamin Shapiro |
Cell canaries for biochemical pathogen detection
|
US20080085839A1
(en)
*
|
2004-09-01 |
2008-04-10 |
Holger Klapproth |
Method For The Analysis Of Point Mutations
|
US20120094298A1
(en)
|
2005-09-02 |
2012-04-19 |
Bioarray Solutions Limited |
Nucleic acid amplification with integrated multiplex detection
|
US20080090739A1
(en)
|
2004-09-30 |
2008-04-17 |
Van Beuningen Marinus G J |
Masked Solid Porous Supports Allowing Fast And Easy Reagent Exchange To Accelerate Electrode-Based Microarrays
|
US7585664B2
(en)
|
2004-10-14 |
2009-09-08 |
The Hong Kong University Of Science And Technology |
Integrated circuit optical detector for biological detection
|
US20060088844A1
(en)
*
|
2004-10-22 |
2006-04-27 |
Honeywell International Inc. |
Real-time PCR microarray based on evanescent wave biosensor
|
US7785785B2
(en)
|
2004-11-12 |
2010-08-31 |
The Board Of Trustees Of The Leland Stanford Junior University |
Charge perturbation detection system for DNA and other molecules
|
EP1659183A1
(en)
|
2004-11-18 |
2006-05-24 |
Eppendorf Array Technologies |
Real-time quantification of multiple targets on a micro-array
|
JP2006162457A
(en)
|
2004-12-08 |
2006-06-22 |
Canon Inc |
Electric potential measuring device and image forming apparatus
|
US20100003715A1
(en)
|
2004-12-21 |
2010-01-07 |
Francesco Pellegrino |
Biological agent detection and identification system
|
ATE357653T1
(en)
|
2005-01-18 |
2007-04-15 |
Hoffmann La Roche |
FLUORESCENT IMAGING USING TELECENTRIC EXCITATION AND IMAGING OPTICS
|
WO2006087574A2
(en)
|
2005-02-19 |
2006-08-24 |
Geneform Technologies Limited |
Isothermal nucleic acid amplification
|
US9040237B2
(en)
|
2005-03-04 |
2015-05-26 |
Intel Corporation |
Sensor arrays and nucleic acid sequencing applications
|
WO2006099160A2
(en)
|
2005-03-11 |
2006-09-21 |
Stanford University |
Bioluminescence resonance energy transfer (bret) systems and methods of use thereof
|
US9223929B2
(en)
|
2005-03-14 |
2015-12-29 |
The California Institute Of Technology |
Method and apparatus for detection, identification and quantification of single-and multi-analytes in affinity-based sensor arrays
|
WO2006099579A2
(en)
|
2005-03-16 |
2006-09-21 |
Applera Corporation |
Compositions and methods for clonal amplification and analysis of polynucleotides
|
US7738086B2
(en)
|
2005-05-09 |
2010-06-15 |
The Trustees Of Columbia University In The City Of New York |
Active CMOS biosensor chip for fluorescent-based detection
|
FR2892196B1
(en)
|
2005-10-18 |
2008-06-20 |
Genewave Soc Par Actions Simpl |
METHOD FOR MANUFACTURING INTEGRATED DETECTION BIOSENSOR
|
CA2637369A1
(en)
|
2005-11-12 |
2007-05-24 |
Siemens Healthcare Diagnostics Inc. |
Gene expression profiles and methods of use
|
CA2651815A1
(en)
|
2006-05-10 |
2007-11-22 |
Dxterity Diagnostics |
Detection of nucleic acid targets using chemically reactive oligonucleotide probes
|
US7463353B2
(en)
|
2006-05-31 |
2008-12-09 |
Uchicago Argonne, Llc |
Modular, micro-scale, optical array and biodetection system
|
US11001881B2
(en)
|
2006-08-24 |
2021-05-11 |
California Institute Of Technology |
Methods for detecting analytes
|
WO2007143669A2
(en)
|
2006-06-05 |
2007-12-13 |
California Institute Of Technology |
Real time micro arrays
|
US11098345B2
(en)
|
2006-06-05 |
2021-08-24 |
California Institute Of Technology |
Methods for detecting target analytes
|
US8637436B2
(en)
|
2006-08-24 |
2014-01-28 |
California Institute Of Technology |
Integrated semiconductor bioarray
|
RU2008148143A
(en)
|
2006-06-08 |
2010-06-10 |
Конинклейке Филипс Электроникс Н.В. (Nl) |
MICROELECTRONIC SENSOR DEVICE FOR DNA DETECTION
|
WO2008012728A1
(en)
|
2006-07-27 |
2008-01-31 |
Koninklijke Philips Electronics N.V. |
Device for molecular diagnosis
|
US8048626B2
(en)
|
2006-07-28 |
2011-11-01 |
California Institute Of Technology |
Multiplex Q-PCR arrays
|
US11525156B2
(en)
|
2006-07-28 |
2022-12-13 |
California Institute Of Technology |
Multiplex Q-PCR arrays
|
US20080027008A1
(en)
|
2006-07-31 |
2008-01-31 |
Jack Henkin |
Antitumorigenic Drug Combination
|
WO2008082713A2
(en)
|
2006-08-24 |
2008-07-10 |
California Institute Of Technology |
Integrated semiconductor bioarray
|
US11560588B2
(en)
|
2006-08-24 |
2023-01-24 |
California Institute Of Technology |
Multiplex Q-PCR arrays
|
US20100240544A1
(en)
|
2006-09-29 |
2010-09-23 |
Liu David J |
Aptamer biochip for multiplexed detection of biomolecules
|
US9114398B2
(en)
|
2006-11-29 |
2015-08-25 |
Canon U.S. Life Sciences, Inc. |
Device and method for digital multiplex PCR assays
|
WO2008143646A2
(en)
|
2006-11-29 |
2008-11-27 |
Canon U.S. Life Sciences, Inc. |
Device and method for digital multiplex pcr assays
|
EP2857526B1
(en)
|
2006-12-13 |
2016-08-17 |
Luminex Corporation |
Systems and methods for multiplex analysis of PCR in real time
|
EP4134667A1
(en)
|
2006-12-14 |
2023-02-15 |
Life Technologies Corporation |
Apparatus for measuring analytes using fet arrays
|
US8349167B2
(en)
|
2006-12-14 |
2013-01-08 |
Life Technologies Corporation |
Methods and apparatus for detecting molecular interactions using FET arrays
|
US7932034B2
(en)
|
2006-12-20 |
2011-04-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Heat and pH measurement for sequencing of DNA
|
US8999724B2
(en)
|
2006-12-28 |
2015-04-07 |
Intel Corporation |
Method and apparatus for match quality analysis of analyte binding
|
CA2676570C
(en)
|
2007-01-26 |
2016-05-03 |
Illumina, Inc. |
Nucleic acid sequencing system and method
|
US8315817B2
(en)
|
2007-01-26 |
2012-11-20 |
Illumina, Inc. |
Independently removable nucleic acid sequencing system and method
|
EP1956097A1
(en)
|
2007-02-06 |
2008-08-13 |
bioMerieux B.V. |
Method for discriminating single nucleotide polymorphisms (SNPs)
|
EP1995327A1
(en)
|
2007-05-21 |
2008-11-26 |
Humboldt Universität zu Berlin |
Probe for detecting a particular nucleic acid sequence
|
ES2453108T3
(en)
|
2007-08-06 |
2014-04-04 |
Orion Genomics, Llc |
New single nucleotide polymorphisms and combinations of new and known polymorphisms to determine the specific allele expression of the IGF2 gene
|
DE102007044664B4
(en)
|
2007-09-18 |
2012-01-05 |
Friz Biochem Gesellschaft Für Bioanalytik Mbh |
Displacement Assay for the Detection of Nucleic Acid Oligomer Hybridization Events
|
US8957002B2
(en)
|
2007-11-05 |
2015-02-17 |
University Of Rochester |
DNA microarray having hairpin probes tethered to nanostructured metal surface
|
WO2009082706A1
(en)
|
2007-12-21 |
2009-07-02 |
The Trustees Of Columbia University In The City Of New York |
Active cmos sensor array for electrochemical biomolecular detection
|
EP2240613B1
(en)
|
2008-02-06 |
2013-09-11 |
Ludwig-Maximilians-Universität München |
Thermo-optical characterisation of nucleic acid molecules
|
EP2307545A4
(en)
|
2008-06-18 |
2011-11-30 |
Ge Healthcare Bio Sciences |
Method for separation of double-stranded and single-stranded nucleic acids from the same sample
|
EP2138587A1
(en)
|
2008-06-23 |
2009-12-30 |
Koninklijke Philips Electronics N.V. |
Amplification of nucleic acids using temperature zones
|
US9393566B2
(en)
|
2008-06-23 |
2016-07-19 |
Canon U.S. Life Sciences, Inc. |
System and method for temperature referencing for melt curve data collection
|
WO2009158451A1
(en)
|
2008-06-25 |
2009-12-30 |
Real-Time Genomics, Llc |
Method and apparatus for melting curve analysis of nucleic acids in microarray format
|
US8058005B2
(en)
|
2008-10-23 |
2011-11-15 |
Honeywell International Inc. |
Method for single nucleotide polymorphism and mutation detection using real time polymerase chain reaction microarray
|
US20100122904A1
(en)
|
2008-11-17 |
2010-05-20 |
Board Of Regents, The University Of Texas System |
Incorporating cmos integrated circuits in the design of affinity-based biosensor systems
|
JP2012509078A
(en)
|
2008-11-21 |
2012-04-19 |
コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ |
Real-time multiplex PCR detection on solid surface using double-stranded nucleic acid specific dye
|
WO2010070923A1
(en)
|
2008-12-18 |
2010-06-24 |
パナソニック株式会社 |
Disk device
|
EP2391883B1
(en)
|
2009-01-30 |
2018-03-07 |
Micronics, Inc. |
Portable high gain fluorescence detection system
|
EP2504449B1
(en)
|
2009-11-25 |
2016-03-23 |
Gen9, Inc. |
Methods and apparatuses for chip-based dna error reduction
|
US20110236983A1
(en)
|
2009-12-29 |
2011-09-29 |
Joseph Beechem |
Single molecule detection and sequencing using fluorescence lifetime imaging
|
US20110312709A1
(en)
|
2010-06-17 |
2011-12-22 |
Geneasys Pty Ltd |
Loc device for detecting target nucleic acid sequences using electrochemiluminescent probes and calibration probes with detection photosensors and calibration photosensors
|
WO2012030995A2
(en)
|
2010-08-31 |
2012-03-08 |
Canon U.S. Life Sciences, Inc. |
Optical system for high resolution thermal melt detection
|
KR20120042100A
(en)
|
2010-10-22 |
2012-05-03 |
주식회사 씨젠 |
Detection of target nucleic acid sequences using dual-labeled immobilized probes on solid phase
|
ES2860945T3
(en)
|
2010-12-27 |
2021-10-05 |
Abbott Molecular Inc |
Quantification of high titer samples by digital PCR
|
US20120295805A1
(en)
|
2011-05-18 |
2012-11-22 |
Polytechnic Institute Of New York University |
Solid phase methods for thermodynamic and kinetic quantification of interactions between nucleic acids and small molecules
|
CN102433376B
(en)
|
2011-10-19 |
2013-07-31 |
上海千友生物科技有限公司 |
Fluorescence quenching-based genetic variation detection method and probe
|
WO2013074796A1
(en)
|
2011-11-15 |
2013-05-23 |
The Board Of Trustees Of The University Of Illinois |
Thermal control of droplets by nanoscale field effect transistors
|
BR112014012773A2
(en)
|
2011-11-29 |
2019-09-24 |
Agrigenetics Inc |
high yield single nucleotide polymorphism assay
|
ES2625065T3
(en)
|
2011-12-09 |
2017-07-18 |
Sietze Sietzema |
Method of detection of bacteria in milk
|
CN104379760B
(en)
|
2012-04-05 |
2018-03-16 |
Bd公司 |
Sample preparation for flow cytometry
|
WO2013158280A1
(en)
|
2012-04-20 |
2013-10-24 |
The Trustees Of Columbia University In The City Of New York |
Systems and methods for single-molecule nucleic-acid assay platforms
|
US9341589B2
(en)
|
2012-06-20 |
2016-05-17 |
Board Of Regents, The University Of Texas System |
Active-electrode integrated biosensor array and methods for use thereof
|
US8969781B2
(en)
|
2012-06-28 |
2015-03-03 |
Board Of Regents, The University Of Texas System |
Integrated optical biosensor array including charge injection circuit and quantizer circuit
|
WO2014089368A1
(en)
|
2012-12-05 |
2014-06-12 |
Bio-Rad Laboratories, Inc |
Methods for polymerase chain reaction copy number variation assays
|
US9718056B2
(en)
|
2013-03-15 |
2017-08-01 |
Syracuse University |
Microfluidics polymerase chain reaction and high resolution melt detection
|
US9983163B2
(en)
|
2013-04-30 |
2018-05-29 |
Board Of Regents, The University Of Texas System |
Integrated electro-analytical biosensor array
|
TWI527905B
(en)
|
2013-11-06 |
2016-04-01 |
國立台灣大學 |
Method of snp detection by using gene detection technique in bead-based microfluidics
|
WO2016023010A1
(en)
|
2014-08-08 |
2016-02-11 |
Quantum-Si Incorporated |
Optical system and assay chip for probing, detecting, and analyzing molecules
|
US9708647B2
(en)
|
2015-03-23 |
2017-07-18 |
Insilixa, Inc. |
Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays
|
US9499861B1
(en)
|
2015-09-10 |
2016-11-22 |
Insilixa, Inc. |
Methods and systems for multiplex quantitative nucleic acid amplification
|
EP3859333A1
(en)
|
2015-09-10 |
2021-08-04 |
InSilixa, Inc. |
Systems for multiplex quantitative nucleic acid amplification
|
WO2017155858A1
(en)
|
2016-03-07 |
2017-09-14 |
Insilixa, Inc. |
Nucleic acid sequence identification using solid-phase cyclic single base extension
|
WO2018050501A1
(en)
|
2016-09-14 |
2018-03-22 |
Radiometer Medical Aps |
System and method for time-resolved fluoroimmunoassay detection
|
WO2020186252A1
(en)
|
2019-03-14 |
2020-09-17 |
Insilixa, Inc. |
Methods and systems for time-gated fluorescent-based detection
|
EP3937780A4
(en)
|
2019-03-14 |
2022-12-07 |
InSilixa, Inc. |
Methods and systems for time-gated fluorescent-based detection
|