DE602004022923D1 - Streptococcus pyogenes antigene - Google Patents

Streptococcus pyogenes antigene

Info

Publication number
DE602004022923D1
DE602004022923D1 DE602004022923T DE602004022923T DE602004022923D1 DE 602004022923 D1 DE602004022923 D1 DE 602004022923D1 DE 602004022923 T DE602004022923 T DE 602004022923T DE 602004022923 T DE602004022923 T DE 602004022923T DE 602004022923 D1 DE602004022923 D1 DE 602004022923D1
Authority
DE
Germany
Prior art keywords
antigene
streptococcus pyogenes
antigens
hyperimmune serum
serum reactive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004022923T
Other languages
English (en)
Inventor
Andreas Meinke
Eszter Nagy
Birgit Winkler
Dieter Gelbmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Valneva Austria GmbH
Original Assignee
Intercell Austria AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intercell Austria AG filed Critical Intercell Austria AG
Publication of DE602004022923D1 publication Critical patent/DE602004022923D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0208—Specific bacteria not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1275—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Streptococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE602004022923T 2003-03-04 2004-03-02 Streptococcus pyogenes antigene Expired - Lifetime DE602004022923D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03450061 2003-03-04
PCT/EP2004/002087 WO2004078907A2 (en) 2003-03-04 2004-03-02 Streptococcus pyogenes antigens

Publications (1)

Publication Number Publication Date
DE602004022923D1 true DE602004022923D1 (de) 2009-10-15

Family

ID=32946995

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004022923T Expired - Lifetime DE602004022923D1 (de) 2003-03-04 2004-03-02 Streptococcus pyogenes antigene

Country Status (16)

Country Link
US (3) US7638136B2 (de)
EP (8) EP2287313A1 (de)
JP (2) JP2006520202A (de)
CN (2) CN1756843B (de)
AT (1) ATE441715T1 (de)
AU (2) AU2004218284B2 (de)
CA (1) CA2517518A1 (de)
CY (1) CY1109683T1 (de)
DE (1) DE602004022923D1 (de)
DK (1) DK1601770T3 (de)
ES (1) ES2330334T3 (de)
HK (1) HK1084977A1 (de)
PL (1) PL1601770T3 (de)
PT (1) PT1601770E (de)
SI (1) SI1601770T1 (de)
WO (1) WO2004078907A2 (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2189473A3 (de) 2000-10-27 2010-08-11 Novartis Vaccines and Diagnostics S.r.l. Nukleinsäure und Proteine von Gruppen A und B Streptokokken
CA2438921C (en) 2001-02-21 2012-04-10 Shire Biochem Inc. Streptococcus pyogenes polypeptides and corresponding dna fragments
AU2003260102A1 (en) * 2002-08-26 2004-03-11 Chiron Corporation Conserved and specific streptococcal genomes
PT1648500E (pt) * 2003-07-31 2014-10-10 Novartis Vaccines & Diagnostic Composições imunogénicas para estreptococos piogenes
ITRM20030376A1 (it) 2003-07-31 2005-02-01 Univ Roma Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia.
US8945589B2 (en) 2003-09-15 2015-02-03 Novartis Vaccines And Diagnostics, Srl Immunogenic compositions for Streptococcus agalactiae
WO2006078318A2 (en) 2004-07-29 2006-07-27 Novartis Vaccines And Diagnostics Inc. Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae
AU2005294275B2 (en) * 2004-10-08 2012-09-13 Glaxosmithkline Biologicals S.A. Immunogenic and therapeutic compositions for Streptococcus pyogenes
US11660317B2 (en) 2004-11-08 2023-05-30 The Johns Hopkins University Compositions comprising cardiosphere-derived cells for use in cell therapy
ES2531483T3 (es) 2005-06-15 2015-03-16 The Ohio State University Research Foundation Péptidos HER-2
DK2336362T3 (en) * 2005-08-26 2019-01-21 Dupont Nutrition Biosci Aps USE OF CRISPR-ASSOCIATED GENES (CAS)
DK2054431T3 (da) * 2006-06-09 2012-01-02 Novartis Ag Konformere af bakterielle adhæsiner
EP2292644A3 (de) 2006-07-07 2011-05-25 Intercell AG Kleine Streptococcus-pyogenes-Antigene und Verwendung dafür
US20110038879A1 (en) * 2006-10-30 2011-02-17 Novartis Ag Immunogenic and therapeutic compositions for streptococcus pyogenes
BRPI0604997A (pt) 2006-11-30 2007-05-22 Fundacao Zerbini vacina contra o estreptococo beta hemolìtico do grupo a, e respectivo processo de obtenção
GB0624874D0 (en) * 2006-12-13 2007-01-24 Hansa Medical Ab Treatment
AU2008242250B2 (en) * 2007-04-19 2014-03-27 Molecular Detection Inc. Methods, compositions and kits for detection and analysis of antibiotic-resistant bacteria
WO2009003291A1 (en) * 2007-07-03 2009-01-08 Mount Sinai Hospital Therapeutics and diagnostics for group a streptococci
BRPI0816689B1 (pt) 2007-09-12 2021-08-24 Novartis Ag Composição de vacina, kit e método para a confecção de uma composição de vacina para a prevenção ou tratamento de infecção por streptococcus pyogenes
AU2013203022B2 (en) * 2007-09-12 2015-09-03 Glaxosmithkline Biologicals S.A. GAS57 mutant antigens and GAS57 antibodies
CN104292312A (zh) * 2007-12-21 2015-01-21 诺华股份有限公司 链球菌溶血素o的突变形式
MX2010014355A (es) * 2008-06-20 2011-03-21 Wyeth Llc Star Composiciones y procedimientos de uso de la orf 554 de cepas estreptocócicas beta-hemolíticas.
BRPI0921286B8 (pt) 2008-11-05 2022-10-25 Wyeth Llc Composição imunogênica com múltiplos componentes para a prevenção de doença por estreptococos beta-hemolíticos (bhs).
US20100234283A1 (en) 2009-02-04 2010-09-16 The Ohio State University Research Foundation Immunogenic epitopes, peptidomimetics, and anti-peptide antibodies, and methods of their use
GB0918392D0 (en) * 2009-10-20 2009-12-02 Novartis Ag Diagnostic and therapeutic methods
WO2013166281A1 (en) * 2012-05-02 2013-11-07 Cedars-Sinai Medical Center Bi-functional compositions for targeting cells to diseased tissues and methods of using same
US9249392B2 (en) 2010-04-30 2016-02-02 Cedars-Sinai Medical Center Methods and compositions for maintaining genomic stability in cultured stem cells
US9845457B2 (en) 2010-04-30 2017-12-19 Cedars-Sinai Medical Center Maintenance of genomic stability in cultured stem cells
US9884076B2 (en) 2012-06-05 2018-02-06 Capricor, Inc. Optimized methods for generation of cardiac stem cells from cardiac tissue and their use in cardiac therapy
CA2881394C (en) 2012-08-13 2024-05-14 Cedars-Sinai Medical Center Exosomes and micro-ribonucleic acids for tissue regeneration
US9650425B2 (en) * 2013-02-11 2017-05-16 University Of Tennessee Research Foundation Group A streptococcal M-related proteins and methods of use
WO2016054591A1 (en) 2014-10-03 2016-04-07 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
GB201502306D0 (en) * 2015-02-12 2015-04-01 Hansa Medical Ab Protein
US10329601B2 (en) * 2015-12-28 2019-06-25 Ionian Technologies, Inc. Nicking and extension amplification reaction (NEAR) of Streptococcus species
EP3402543B1 (de) 2016-01-11 2021-09-08 Cedars-Sinai Medical Center Aus kardiosphäre stammende zellen und durch solche zellen sekretierte exosomen in der behandlung von herzversagen mit konservierter auswurffraktion
US11351200B2 (en) 2016-06-03 2022-06-07 Cedars-Sinai Medical Center CDC-derived exosomes for treatment of ventricular tachyarrythmias
US11541078B2 (en) 2016-09-20 2023-01-03 Cedars-Sinai Medical Center Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders
US11759482B2 (en) 2017-04-19 2023-09-19 Cedars-Sinai Medical Center Methods and compositions for treating skeletal muscular dystrophy
CN110785662A (zh) * 2017-04-26 2020-02-11 奥克兰联合服务有限公司 分析和治疗方法和组合物及其用途
WO2019126068A1 (en) 2017-12-20 2019-06-27 Cedars-Sinai Medical Center Engineered extracellular vesicles for enhanced tissue delivery
JP2020117470A (ja) * 2019-01-25 2020-08-06 公益財団法人ヒューマンサイエンス振興財団 抗体並びに劇症型溶血性レンサ球菌感染症を予防及び／又は治療するための薬剤
CN110438261B (zh) * 2019-07-29 2022-08-12 华南农业大学 用于检测f亚群禽白血病病毒的分子标记、引物、试剂盒及应用
EP4377329A1 (de) * 2021-07-29 2024-06-05 Université de Lausanne Neuartige pneumokokken-polypeptidantigene
CN117417427B (zh) * 2023-09-11 2024-05-07 江苏省人民医院（南京医科大学第一附属医院） 一种检测内源性自体胰岛素介导的胰岛素抗体的试剂盒

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB234771A (en) * 1924-06-02 1926-02-11 S T Leigh And Company Ltd Improved means for inserting cork discs, or the like, into caps or covers
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
EP1493825A3 (de) 1990-06-11 2005-02-09 Gilead Sciences, Inc. Verfahren zur Herstellung von Nukleinsäureliganden
ES2251009T3 (es) 1990-06-28 2006-04-16 Sanofi-Aventis Deutschland Gmbh Proteinas de fusion con partes de inmunoglobulinas, su preparacion y uso.
RU2148587C1 (ru) * 1991-06-24 2000-05-10 Чирон Корпорейшн Полипептид и способ его получения, реагент для иммуноанализа, способ определения присутствия антител и способ индукции иммунного ответа
DK0772619T4 (da) 1994-07-15 2011-02-21 Univ Iowa Res Found Immunmodulatoriske oligonukleotider
KR19990022742A (ko) * 1995-06-07 1999-03-25 샤르레 아. 테시에르 스트렙토코커스 속 유래의 hsp70 계열의 쇼크 단백질
CO4600681A1 (es) 1996-02-24 1998-05-08 Boehringer Ingelheim Pharma Composicion farmaceutica para la modulacion inmunitaria
AU743469C (en) 1996-08-30 2004-02-12 Rolf Bald Mirror-symmetrical selection and evolution of nucleic acids
US6958239B2 (en) 1996-11-21 2005-10-25 Oligos Etc Inc. Three component chimeric antisense oligonucleotides
US5849902A (en) 1996-09-26 1998-12-15 Oligos Etc. Inc. Three component chimeric antisense oligonucleotides
JP3515314B2 (ja) * 1997-03-25 2004-04-05 扶桑薬品工業株式会社 ストレプトコッカス・ピオゲネス菌に起因する感染症の診断用プローブ
DE19742706B4 (de) 1997-09-26 2013-07-25 Pieris Proteolab Ag Lipocalinmuteine
DE19803453A1 (de) 1998-01-30 1999-08-12 Boehringer Ingelheim Int Vakzine
KR100891398B1 (ko) * 1998-12-23 2009-04-02 아이디 바이오메디칼 코포레이션 신규한 스트렙토코커스 항원
AT408721B (de) 1999-10-01 2002-02-25 Cistem Biotechnologies Gmbh Pharmazeutische zusammensetzung enthaltend ein antigen
WO2001049721A2 (en) 1999-12-30 2001-07-12 Bristol-Myers Squibb Company Bacterial genes and proteins that are essential for cell viability and their uses
AT409085B (de) 2000-01-28 2002-05-27 Cistem Biotechnologies Gmbh Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen
DE60130877T2 (de) 2000-04-14 2008-07-17 Intercell Ag Modifizierte peptide enthaltende pharmazeutische präparationen
HU228264B1 (en) 2000-06-08 2013-02-28 Intercell Ag Immunostimulatory oligodeoxynucleotides
AT410173B (de) 2000-06-08 2003-02-25 Cistem Biotechnologies Gmbh Antigene zusammensetzung
AU2000279060A1 (en) 2000-07-10 2002-01-21 Telefonaktiebolaget Lm Ericsson (Publ) Resource management in uncoordinated frequency hopping system
WO2002013857A2 (en) 2000-08-17 2002-02-21 Intercell Biomedizinische Forschungs- Und Entwicklungs Ag A vaccine which comprises at least one antigen and a cathelididin derived antimicrobial peptide or a derivative thereof
AT410635B (de) 2000-10-18 2003-06-25 Cistem Biotechnologies Gmbh Vakzin-zusammensetzung
EP2189473A3 (de) * 2000-10-27 2010-08-11 Novartis Vaccines and Diagnostics S.r.l. Nukleinsäure und Proteine von Gruppen A und B Streptokokken
AT410798B (de) 2001-01-26 2003-07-25 Cistem Biotechnologies Gmbh Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen
CA2438921C (en) * 2001-02-21 2012-04-10 Shire Biochem Inc. Streptococcus pyogenes polypeptides and corresponding dna fragments
WO2002077183A2 (en) * 2001-03-21 2002-10-03 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
GB0107658D0 (en) * 2001-03-27 2001-05-16 Chiron Spa Streptococcus pneumoniae
BR0208874A (pt) * 2001-04-13 2004-06-22 Wyeth Corp Proteìnas superficiais de streptococcus pyogenes
KR20080081201A (ko) 2001-04-16 2008-09-08 와이어쓰 홀딩스 코포레이션 폴리펩티드 항원을 암호화하는 신규한 스트렙토코쿠스뉴모니애 개방형 판독 프레임 및 이를 포함하는 조성물
FR2824074A1 (fr) * 2001-04-26 2002-10-31 Pasteur Institut Sequence du genome streptococcus agalactiae, application au developpement de vaccins, d'outils de diagnostic, et a l'identification de cibles therapeutiques
GB0210128D0 (en) * 2002-05-02 2002-06-12 Chiron Spa Nucleic acids and proteins from streptococcus groups A & B
CA2511103C (en) * 2002-12-20 2020-02-11 University Of Medicine And Dentistry Of New Jersey Compositions and methods for enzymatic detachment of bacterial and fungal biofilms
PT1648500E (pt) * 2003-07-31 2014-10-10 Novartis Vaccines & Diagnostic Composições imunogénicas para estreptococos piogenes
EP2292644A3 (de) * 2006-07-07 2011-05-25 Intercell AG Kleine Streptococcus-pyogenes-Antigene und Verwendung dafür
EP2045869A1 (de) 2007-10-02 2009-04-08 Rohde & Schwarz GmbH & Co. KG Richtkoppler

Also Published As

Publication number Publication date
AU2004218284A1 (en) 2004-09-16
SI1601770T1 (sl) 2010-01-29
CN1756843B (zh) 2012-03-21
DK1601770T3 (da) 2009-11-02
US20060194751A1 (en) 2006-08-31
EP2287313A1 (de) 2011-02-23
HK1084977A1 (en) 2006-08-11
EP2287314A1 (de) 2011-02-23
US7638136B2 (en) 2009-12-29
JP2006520202A (ja) 2006-09-07
CY1109683T1 (el) 2014-08-13
WO2004078907A3 (en) 2005-03-10
US20100255034A1 (en) 2010-10-07
EP1601770B1 (de) 2009-09-02
US8349336B2 (en) 2013-01-08
EP2287312A1 (de) 2011-02-23
WO2004078907A2 (en) 2004-09-16
AU2009230772A1 (en) 2009-11-26
AU2009230772B2 (en) 2013-07-18
CN102512670A (zh) 2012-06-27
JP2011015689A (ja) 2011-01-27
CN1756843A (zh) 2006-04-05
EP1601770A2 (de) 2005-12-07
EP2287311A1 (de) 2011-02-23
EP2053125B1 (de) 2014-04-30
EP2287315A1 (de) 2011-02-23
EP2290082A1 (de) 2011-03-02
ATE441715T1 (de) 2009-09-15
AU2004218284B2 (en) 2009-07-23
US20130122047A1 (en) 2013-05-16
PT1601770E (pt) 2009-12-07
ES2330334T3 (es) 2009-12-09
PL1601770T3 (pl) 2010-02-26
CA2517518A1 (en) 2004-09-16
EP2053125A1 (de) 2009-04-29

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