DE602004016771D1 - Radikalfänger bei der fluorierung von iodiniumsalz - Google Patents

Radikalfänger bei der fluorierung von iodiniumsalz

Info

Publication number
DE602004016771D1
DE602004016771D1 DE602004016771T DE602004016771T DE602004016771D1 DE 602004016771 D1 DE602004016771 D1 DE 602004016771D1 DE 602004016771 T DE602004016771 T DE 602004016771T DE 602004016771 T DE602004016771 T DE 602004016771T DE 602004016771 D1 DE602004016771 D1 DE 602004016771D1
Authority
DE
Germany
Prior art keywords
iodonium salts
reaction
solid phase
radikalenger
fluoration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004016771T
Other languages
German (de)
English (en)
Inventor
Harry John Wadsworth
David Arthur Widdowson
Emmanuelle Wilson
Michael Andrew Carroll
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
GE Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Ltd filed Critical GE Healthcare Ltd
Publication of DE602004016771D1 publication Critical patent/DE602004016771D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Liquid Crystal (AREA)
  • Saccharide Compounds (AREA)
  • Seasonings (AREA)
DE602004016771T 2003-12-23 2004-12-17 Radikalfänger bei der fluorierung von iodiniumsalz Expired - Lifetime DE602004016771D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0329716.5A GB0329716D0 (en) 2003-12-23 2003-12-23 Radical trap
PCT/GB2004/005304 WO2005061415A1 (en) 2003-12-23 2004-12-17 Radical trap in fluoridation of iodonium salt

Publications (1)

Publication Number Publication Date
DE602004016771D1 true DE602004016771D1 (de) 2008-11-06

Family

ID=30776291

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004016771T Expired - Lifetime DE602004016771D1 (de) 2003-12-23 2004-12-17 Radikalfänger bei der fluorierung von iodiniumsalz

Country Status (9)

Country Link
US (1) US7642373B2 (https=)
EP (1) EP1697279B1 (https=)
JP (1) JP4809244B2 (https=)
CN (1) CN100415696C (https=)
AT (1) ATE409173T1 (https=)
DE (1) DE602004016771D1 (https=)
ES (1) ES2313117T3 (https=)
GB (1) GB0329716D0 (https=)
WO (1) WO2005061415A1 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0407952D0 (en) * 2004-04-08 2004-05-12 Amersham Plc Fluoridation method
GB0525949D0 (en) 2005-12-21 2006-02-01 Hammersmith Imanet Ltd Pet radiotracers
EP2192928A4 (en) * 2007-10-03 2011-04-06 Ge Healthcare Ltd PERFLUOR ARYLIODONIUM SALTS IN A NUCLEOPHILIC AROMATIC 18F FLUORATION
EP2238074A2 (en) * 2008-01-03 2010-10-13 GE Healthcare UK Limited Fluoride processing method
GB0808986D0 (en) 2008-05-16 2008-06-25 Univ Newcastle Formation of 18F and 19F fluoroarenes bearing reactive functionalities
WO2010015340A1 (en) * 2008-08-06 2010-02-11 Bayer Schering Pharma Aktiengesellschaft Daa-pyridine as peripheral benzodiazepine receptor ligand for diagnostic imaging and pharmaceutical treatment
GB0814893D0 (en) * 2008-08-14 2008-09-17 Ge Healthcare Ltd Improved fluoridation of iodonium salts
US9302990B2 (en) 2008-10-21 2016-04-05 Nutech Ventures Fluorination of aromatic ring systems
EP2537826B1 (en) 2008-10-21 2017-03-08 Nutech Ventures, Inc. Fluorination of aromatic ring systems
GB0905438D0 (en) 2009-03-30 2009-05-13 Ge Healthcare Ltd Radiolabelling reagents and methods
WO2010117435A2 (en) * 2009-04-08 2010-10-14 The Regents Of The University Of California No-carrier-added nucleophilic [f-18] fluorination of aromatic compounds
US8377704B2 (en) 2009-10-20 2013-02-19 Nutech Ventures Detection and quantification of anions
US8546578B2 (en) * 2010-02-04 2013-10-01 Nutech Ventures Iodonium Cyclophanes for SECURE arene functionalization
WO2011141515A1 (en) 2010-05-14 2011-11-17 Bayer Pharma Aktiengesellschaft Diagnostic agents for amyloid beta imaging
KR101441406B1 (ko) * 2011-05-25 2014-11-04 주식회사 바이오이미징코리아 디아릴이오도늄 염 전구체를 이용한 플로오린-18이 표지된 플루마제닐의 제조 방법
EP2912011A4 (en) * 2012-10-27 2016-11-09 Ground Fluor Pharmaceuticals Inc METHODS AND REAGENTS FOR MANUFACTURING DIARYLIODONIUM SALTS
EP2821383B1 (en) * 2013-07-02 2017-08-30 Trasis S.A. Stabilization of radiosynthetic intermediates
WO2015157597A1 (en) * 2014-04-11 2015-10-15 The Regents Of The University Of Michigan Copper catalyzed [18f]fluorination of iodonium salts
CN105237483B (zh) * 2015-11-10 2018-04-20 东华大学 一种对称型嘧啶基碘鎓盐及其制备方法
FR3054445B1 (fr) * 2016-07-26 2019-07-05 Laboratoires Cyclopharma Synthese d'une composition d'agent radioactif
US10695450B2 (en) 2016-07-26 2020-06-30 Laboratoires Cyclopharma Synthesis of a radioactive agent composition
RU2020116649A (ru) 2017-10-24 2021-11-30 Лунелла Байотек, Инк. Митофлавосцины: нацеливание на флавин-содержащие ферменты устраняет злокачественные стволовые клетки (cscs) посредством ингибирования митохондриального дыхания
GB201805253D0 (en) * 2018-03-29 2018-05-16 Ge Healthcare Ltd Ip Solid phase extraction
JP7556709B2 (ja) * 2019-07-01 2024-09-26 住友化学株式会社 カルボン酸塩、カルボン酸発生剤、レジスト組成物及びレジストパターンの製造方法
JP7627551B2 (ja) * 2019-07-01 2025-02-06 住友化学株式会社 塩、酸発生剤、レジスト組成物及びレジストパターンの製造方法
JP7558694B2 (ja) * 2019-07-01 2024-10-01 住友化学株式会社 塩、酸発生剤、レジスト組成物及びレジストパターンの製造方法
JP2021008455A (ja) * 2019-07-01 2021-01-28 住友化学株式会社 カルボン酸塩、カルボン酸発生剤、レジスト組成物及びレジストパターンの製造方法
GB201915206D0 (en) 2019-10-21 2019-12-04 Ge Healthcare Ltd Use of cyclodextrins as a radiostabilizer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52133994A (en) * 1976-04-29 1977-11-09 Daikin Ind Ltd Method of fluorination
JP3165775B2 (ja) * 1994-08-31 2001-05-14 日本鋼管株式会社 フッ素放射性同位元素標識ｌ−ドーパの製造方法
JP3171036B2 (ja) * 1994-11-16 2001-05-28 日本鋼管株式会社 フッ素放射性同位元素標識ドーパミンの製造方法
GB0115927D0 (en) * 2001-06-29 2001-08-22 Nycomed Amersham Plc Solid-phase nucleophilic fluorination
GB0206750D0 (en) * 2002-03-22 2002-05-01 Amersham Plc Radiofluorination methods
DE10346228B4 (de) * 2003-09-25 2009-04-09 Eberhard-Karls-Universität Tübingen Universitätsklinikum Herstellung von [18F]fluormarkierten aromatischen L-Aminosäuren
GB0407952D0 (en) * 2004-04-08 2004-05-12 Amersham Plc Fluoridation method

Also Published As

Publication number Publication date
EP1697279B1 (en) 2008-09-24
EP1697279A1 (en) 2006-09-06
WO2005061415A1 (en) 2005-07-07
JP2007515465A (ja) 2007-06-14
US7642373B2 (en) 2010-01-05
US20060292060A1 (en) 2006-12-28
ES2313117T3 (es) 2009-03-01
GB0329716D0 (en) 2004-01-28
CN100415696C (zh) 2008-09-03
JP4809244B2 (ja) 2011-11-09
ATE409173T1 (de) 2008-10-15
CN1898184A (zh) 2007-01-17

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