CN100415696C - 碘盐氟化中的自由基捕获剂 - Google Patents

碘盐氟化中的自由基捕获剂 Download PDF

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Publication number
CN100415696C
CN100415696C CNB2004800384699A CN200480038469A CN100415696C CN 100415696 C CN100415696 C CN 100415696C CN B2004800384699 A CNB2004800384699 A CN B2004800384699A CN 200480038469 A CN200480038469 A CN 200480038469A CN 100415696 C CN100415696 C CN 100415696C
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China
Prior art keywords
group
compound
formula
labeled compound
iodine
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CNB2004800384699A
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English (en)
Chinese (zh)
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CN1898184A (zh
Inventor
H·J·沃兹沃思
D·A·维道森
E·威尔逊
M·A·卡洛尔
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GE Healthcare Ltd
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GE Healthcare Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Liquid Crystal (AREA)
  • Saccharide Compounds (AREA)
  • Seasonings (AREA)
CNB2004800384699A 2003-12-23 2004-12-17 碘盐氟化中的自由基捕获剂 Expired - Fee Related CN100415696C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0329716.5A GB0329716D0 (en) 2003-12-23 2003-12-23 Radical trap
GB0329716.5 2003-12-23

Publications (2)

Publication Number Publication Date
CN1898184A CN1898184A (zh) 2007-01-17
CN100415696C true CN100415696C (zh) 2008-09-03

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ID=30776291

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CNB2004800384699A Expired - Fee Related CN100415696C (zh) 2003-12-23 2004-12-17 碘盐氟化中的自由基捕获剂

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Country Link
US (1) US7642373B2 (https=)
EP (1) EP1697279B1 (https=)
JP (1) JP4809244B2 (https=)
CN (1) CN100415696C (https=)
AT (1) ATE409173T1 (https=)
DE (1) DE602004016771D1 (https=)
ES (1) ES2313117T3 (https=)
GB (1) GB0329716D0 (https=)
WO (1) WO2005061415A1 (https=)

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GB0407952D0 (en) * 2004-04-08 2004-05-12 Amersham Plc Fluoridation method
GB0525949D0 (en) 2005-12-21 2006-02-01 Hammersmith Imanet Ltd Pet radiotracers
EP2192928A4 (en) * 2007-10-03 2011-04-06 Ge Healthcare Ltd PERFLUOR ARYLIODONIUM SALTS IN A NUCLEOPHILIC AROMATIC 18F FLUORATION
EP2238074A2 (en) * 2008-01-03 2010-10-13 GE Healthcare UK Limited Fluoride processing method
GB0808986D0 (en) 2008-05-16 2008-06-25 Univ Newcastle Formation of 18F and 19F fluoroarenes bearing reactive functionalities
WO2010015340A1 (en) * 2008-08-06 2010-02-11 Bayer Schering Pharma Aktiengesellschaft Daa-pyridine as peripheral benzodiazepine receptor ligand for diagnostic imaging and pharmaceutical treatment
GB0814893D0 (en) * 2008-08-14 2008-09-17 Ge Healthcare Ltd Improved fluoridation of iodonium salts
US9302990B2 (en) 2008-10-21 2016-04-05 Nutech Ventures Fluorination of aromatic ring systems
EP2537826B1 (en) 2008-10-21 2017-03-08 Nutech Ventures, Inc. Fluorination of aromatic ring systems
GB0905438D0 (en) 2009-03-30 2009-05-13 Ge Healthcare Ltd Radiolabelling reagents and methods
WO2010117435A2 (en) * 2009-04-08 2010-10-14 The Regents Of The University Of California No-carrier-added nucleophilic [f-18] fluorination of aromatic compounds
US8377704B2 (en) 2009-10-20 2013-02-19 Nutech Ventures Detection and quantification of anions
US8546578B2 (en) * 2010-02-04 2013-10-01 Nutech Ventures Iodonium Cyclophanes for SECURE arene functionalization
WO2011141515A1 (en) 2010-05-14 2011-11-17 Bayer Pharma Aktiengesellschaft Diagnostic agents for amyloid beta imaging
KR101441406B1 (ko) * 2011-05-25 2014-11-04 주식회사 바이오이미징코리아 디아릴이오도늄 염 전구체를 이용한 플로오린-18이 표지된 플루마제닐의 제조 방법
EP2912011A4 (en) * 2012-10-27 2016-11-09 Ground Fluor Pharmaceuticals Inc METHODS AND REAGENTS FOR MANUFACTURING DIARYLIODONIUM SALTS
EP2821383B1 (en) * 2013-07-02 2017-08-30 Trasis S.A. Stabilization of radiosynthetic intermediates
WO2015157597A1 (en) * 2014-04-11 2015-10-15 The Regents Of The University Of Michigan Copper catalyzed [18f]fluorination of iodonium salts
CN105237483B (zh) * 2015-11-10 2018-04-20 东华大学 一种对称型嘧啶基碘鎓盐及其制备方法
FR3054445B1 (fr) * 2016-07-26 2019-07-05 Laboratoires Cyclopharma Synthese d'une composition d'agent radioactif
US10695450B2 (en) 2016-07-26 2020-06-30 Laboratoires Cyclopharma Synthesis of a radioactive agent composition
RU2020116649A (ru) 2017-10-24 2021-11-30 Лунелла Байотек, Инк. Митофлавосцины: нацеливание на флавин-содержащие ферменты устраняет злокачественные стволовые клетки (cscs) посредством ингибирования митохондриального дыхания
GB201805253D0 (en) * 2018-03-29 2018-05-16 Ge Healthcare Ltd Ip Solid phase extraction
JP7556709B2 (ja) * 2019-07-01 2024-09-26 住友化学株式会社 カルボン酸塩、カルボン酸発生剤、レジスト組成物及びレジストパターンの製造方法
JP7627551B2 (ja) * 2019-07-01 2025-02-06 住友化学株式会社 塩、酸発生剤、レジスト組成物及びレジストパターンの製造方法
JP7558694B2 (ja) * 2019-07-01 2024-10-01 住友化学株式会社 塩、酸発生剤、レジスト組成物及びレジストパターンの製造方法
JP2021008455A (ja) * 2019-07-01 2021-01-28 住友化学株式会社 カルボン酸塩、カルボン酸発生剤、レジスト組成物及びレジストパターンの製造方法
GB201915206D0 (en) 2019-10-21 2019-12-04 Ge Healthcare Ltd Use of cyclodextrins as a radiostabilizer

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003080544A1 (en) * 2002-03-22 2003-10-02 Amersham Plc Radiofluorination methods

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JPS52133994A (en) * 1976-04-29 1977-11-09 Daikin Ind Ltd Method of fluorination
JP3165775B2 (ja) * 1994-08-31 2001-05-14 日本鋼管株式会社 フッ素放射性同位元素標識ｌ−ドーパの製造方法
JP3171036B2 (ja) * 1994-11-16 2001-05-28 日本鋼管株式会社 フッ素放射性同位元素標識ドーパミンの製造方法
GB0115927D0 (en) * 2001-06-29 2001-08-22 Nycomed Amersham Plc Solid-phase nucleophilic fluorination
DE10346228B4 (de) * 2003-09-25 2009-04-09 Eberhard-Karls-Universität Tübingen Universitätsklinikum Herstellung von [18F]fluormarkierten aromatischen L-Aminosäuren
GB0407952D0 (en) * 2004-04-08 2004-05-12 Amersham Plc Fluoridation method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003080544A1 (en) * 2002-03-22 2003-10-02 Amersham Plc Radiofluorination methods

Also Published As

Publication number Publication date
EP1697279B1 (en) 2008-09-24
DE602004016771D1 (de) 2008-11-06
EP1697279A1 (en) 2006-09-06
WO2005061415A1 (en) 2005-07-07
JP2007515465A (ja) 2007-06-14
US7642373B2 (en) 2010-01-05
US20060292060A1 (en) 2006-12-28
ES2313117T3 (es) 2009-03-01
GB0329716D0 (en) 2004-01-28
JP4809244B2 (ja) 2011-11-09
ATE409173T1 (de) 2008-10-15
CN1898184A (zh) 2007-01-17

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