CN100415696C - 碘盐氟化中的自由基捕获剂 - Google Patents

碘盐氟化中的自由基捕获剂 Download PDF

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Publication number
CN100415696C
CN100415696C CNB2004800384699A CN200480038469A CN100415696C CN 100415696 C CN100415696 C CN 100415696C CN B2004800384699 A CNB2004800384699 A CN B2004800384699A CN 200480038469 A CN200480038469 A CN 200480038469A CN 100415696 C CN100415696 C CN 100415696C
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CN
China
Prior art keywords
group
compound
formula
labeled compound
iodine
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Expired - Fee Related
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CNB2004800384699A
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English (en)
Chinese (zh)
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CN1898184A (zh
Inventor
H·J·沃兹沃思
D·A·维道森
E·威尔逊
M·A·卡洛尔
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GE Healthcare Ltd
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GE Healthcare Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Liquid Crystal (AREA)
  • Saccharide Compounds (AREA)
  • Seasonings (AREA)
CNB2004800384699A 2003-12-23 2004-12-17 碘盐氟化中的自由基捕获剂 Expired - Fee Related CN100415696C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0329716.5A GB0329716D0 (en) 2003-12-23 2003-12-23 Radical trap
GB0329716.5 2003-12-23

Publications (2)

Publication Number Publication Date
CN1898184A CN1898184A (zh) 2007-01-17
CN100415696C true CN100415696C (zh) 2008-09-03

Family

ID=30776291

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CNB2004800384699A Expired - Fee Related CN100415696C (zh) 2003-12-23 2004-12-17 碘盐氟化中的自由基捕获剂

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Country Link
US (1) US7642373B2 (https=)
EP (1) EP1697279B1 (https=)
JP (1) JP4809244B2 (https=)
CN (1) CN100415696C (https=)
AT (1) ATE409173T1 (https=)
DE (1) DE602004016771D1 (https=)
ES (1) ES2313117T3 (https=)
GB (1) GB0329716D0 (https=)
WO (1) WO2005061415A1 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0407952D0 (en) * 2004-04-08 2004-05-12 Amersham Plc Fluoridation method
GB0525949D0 (en) * 2005-12-21 2006-02-01 Hammersmith Imanet Ltd Pet radiotracers
WO2009073273A2 (en) * 2007-10-03 2009-06-11 Ge Healthcare Limited Perfluoro-aryliodonium salts in nucleophilic aromatic 18f-fluorination
US8980221B2 (en) * 2008-01-03 2015-03-17 Ge Healthcare Limited Fluoride processing method
GB0808986D0 (en) 2008-05-16 2008-06-25 Univ Newcastle Formation of 18F and 19F fluoroarenes bearing reactive functionalities
WO2010015340A1 (en) * 2008-08-06 2010-02-11 Bayer Schering Pharma Aktiengesellschaft Daa-pyridine as peripheral benzodiazepine receptor ligand for diagnostic imaging and pharmaceutical treatment
GB0814893D0 (en) * 2008-08-14 2008-09-17 Ge Healthcare Ltd Improved fluoridation of iodonium salts
EP3284736B1 (en) 2008-10-21 2021-03-03 NUtech Ventures Fluorination of aromatic ring systems
US9302990B2 (en) 2008-10-21 2016-04-05 Nutech Ventures Fluorination of aromatic ring systems
GB0905438D0 (en) 2009-03-30 2009-05-13 Ge Healthcare Ltd Radiolabelling reagents and methods
US8742139B2 (en) * 2009-04-08 2014-06-03 The Regents Of The University Of California No-carrier-added nucleophilic [F-18] fluorination of aromatic compounds
US8377704B2 (en) 2009-10-20 2013-02-19 Nutech Ventures Detection and quantification of anions
US8546578B2 (en) 2010-02-04 2013-10-01 Nutech Ventures Iodonium Cyclophanes for SECURE arene functionalization
WO2011141515A1 (en) 2010-05-14 2011-11-17 Bayer Pharma Aktiengesellschaft Diagnostic agents for amyloid beta imaging
KR101441406B1 (ko) * 2011-05-25 2014-11-04 주식회사 바이오이미징코리아 디아릴이오도늄 염 전구체를 이용한 플로오린-18이 표지된 플루마제닐의 제조 방법
AU2013334166A1 (en) * 2012-10-27 2015-05-28 Ground Fluor Pharmaceuticals, Inc. Processes and reagents for making diaryliodonium salts
EP2821383B1 (en) * 2013-07-02 2017-08-30 Trasis S.A. Stabilization of radiosynthetic intermediates
WO2015157597A1 (en) * 2014-04-11 2015-10-15 The Regents Of The University Of Michigan Copper catalyzed [18f]fluorination of iodonium salts
CN105237483B (zh) * 2015-11-10 2018-04-20 东华大学 一种对称型嘧啶基碘鎓盐及其制备方法
FR3054445B1 (fr) * 2016-07-26 2019-07-05 Laboratoires Cyclopharma Synthese d'une composition d'agent radioactif
US10695450B2 (en) 2016-07-26 2020-06-30 Laboratoires Cyclopharma Synthesis of a radioactive agent composition
JP2021500374A (ja) 2017-10-24 2021-01-07 ルネラ・バイオテック・インコーポレーテッド 標的フラビン含有酵素がミトコンドリア呼吸を阻害することにより癌幹細胞（ｃｓｃｓ）を排除するミトフラボスチン
GB201805253D0 (en) * 2018-03-29 2018-05-16 Ge Healthcare Ltd Ip Solid phase extraction
JP2021008455A (ja) * 2019-07-01 2021-01-28 住友化学株式会社 カルボン酸塩、カルボン酸発生剤、レジスト組成物及びレジストパターンの製造方法
JP7558694B2 (ja) * 2019-07-01 2024-10-01 住友化学株式会社 塩、酸発生剤、レジスト組成物及びレジストパターンの製造方法
JP7556709B2 (ja) * 2019-07-01 2024-09-26 住友化学株式会社 カルボン酸塩、カルボン酸発生剤、レジスト組成物及びレジストパターンの製造方法
JP7627551B2 (ja) * 2019-07-01 2025-02-06 住友化学株式会社 塩、酸発生剤、レジスト組成物及びレジストパターンの製造方法
GB201915206D0 (en) 2019-10-21 2019-12-04 Ge Healthcare Ltd Use of cyclodextrins as a radiostabilizer

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003080544A1 (en) * 2002-03-22 2003-10-02 Amersham Plc Radiofluorination methods

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52133994A (en) * 1976-04-29 1977-11-09 Daikin Ind Ltd Method of fluorination
JP3165775B2 (ja) * 1994-08-31 2001-05-14 日本鋼管株式会社 フッ素放射性同位元素標識ｌ−ドーパの製造方法
JP3171036B2 (ja) * 1994-11-16 2001-05-28 日本鋼管株式会社 フッ素放射性同位元素標識ドーパミンの製造方法
GB0115927D0 (en) * 2001-06-29 2001-08-22 Nycomed Amersham Plc Solid-phase nucleophilic fluorination
DE10346228B4 (de) * 2003-09-25 2009-04-09 Eberhard-Karls-Universität Tübingen Universitätsklinikum Herstellung von [18F]fluormarkierten aromatischen L-Aminosäuren
GB0407952D0 (en) * 2004-04-08 2004-05-12 Amersham Plc Fluoridation method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003080544A1 (en) * 2002-03-22 2003-10-02 Amersham Plc Radiofluorination methods

Also Published As

Publication number Publication date
CN1898184A (zh) 2007-01-17
US7642373B2 (en) 2010-01-05
US20060292060A1 (en) 2006-12-28
GB0329716D0 (en) 2004-01-28
JP2007515465A (ja) 2007-06-14
ES2313117T3 (es) 2009-03-01
DE602004016771D1 (de) 2008-11-06
JP4809244B2 (ja) 2011-11-09
WO2005061415A1 (en) 2005-07-07
EP1697279B1 (en) 2008-09-24
ATE409173T1 (de) 2008-10-15
EP1697279A1 (en) 2006-09-06

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