DE60336986D1 - Verfahren zur herstellung von biarylverbindungen - Google Patents
Verfahren zur herstellung von biarylverbindungenInfo
- Publication number
- DE60336986D1 DE60336986D1 DE60336986T DE60336986T DE60336986D1 DE 60336986 D1 DE60336986 D1 DE 60336986D1 DE 60336986 T DE60336986 T DE 60336986T DE 60336986 T DE60336986 T DE 60336986T DE 60336986 D1 DE60336986 D1 DE 60336986D1
- Authority
- DE
- Germany
- Prior art keywords
- production
- biaryl compounds
- biaryl
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B37/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
- C07B37/04—Substitution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002058624 | 2002-03-05 | ||
| JP2002073833 | 2002-03-18 | ||
| PCT/JP2003/002460 WO2003074478A1 (fr) | 2002-03-05 | 2003-03-04 | Procédé de préparation de composés biaryle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60336986D1 true DE60336986D1 (de) | 2011-06-16 |
Family
ID=27790963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60336986T Expired - Lifetime DE60336986D1 (de) | 2002-03-05 | 2003-03-04 | Verfahren zur herstellung von biarylverbindungen |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US7271280B2 (de) |
| EP (2) | EP1481967B1 (de) |
| DE (1) | DE60336986D1 (de) |
| WO (1) | WO2003074478A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100087680A1 (en) * | 2005-07-20 | 2010-04-08 | Sumitomo Chemical Company Limited | Method for producing biaryl compound |
| KR20100040910A (ko) * | 2007-08-10 | 2010-04-21 | 우베 고산 가부시키가이샤 | 방향족 화합물의 제조 방법 |
| CN102229545A (zh) * | 2011-05-09 | 2011-11-02 | 南通维立科化工有限公司 | 丙草胺中间体甲基磺酸-2-丙氧基乙酯生产方法 |
| US10847725B2 (en) * | 2016-06-16 | 2020-11-24 | Nissan Chemical Corporation | Sulfonic acid ester compound and use therefor |
| CN109053495B (zh) * | 2018-07-23 | 2021-05-28 | 江苏宇田医药有限公司 | 一种lcz696中间体的合成方法 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2002A (en) * | 1841-03-12 | Tor and planter for plowing | ||
| DE444892C (de) | 1927-05-31 | A T G Allg Transportanlagen Ge | Anlage zur Gewinnung und Foerderung des Abraums im Tagebau von Braunkohlen o. dgl. | |
| NL300552A (de) * | 1963-11-14 | |||
| JPS53103440A (en) | 1977-02-18 | 1978-09-08 | Tanabe Seiyaku Co Ltd | Separation of optical actvator and dl-isomer of p-hydroxyphenylglycine |
| NZ228855A (en) | 1988-04-25 | 1992-08-26 | Hoffmann La Roche | Tyrosine analogues and peptides containing them especially cholecystokinin (cck) analogues |
| GB9408936D0 (en) | 1994-05-05 | 1994-06-22 | Cancer Res Inst | Anti-cancer compounds |
| DE4443892A1 (de) | 1994-12-09 | 1996-06-13 | Bayer Ag | 4-(Chinolin-2-yl-methoxy)-phenyl-essigsäurederivate |
| IT1277737B1 (it) | 1995-12-28 | 1997-11-12 | Zambon Spa | Derivati tiolici ad attivita' inibitrice delle metallopeptidasi |
| US6194599B1 (en) * | 1997-04-08 | 2001-02-27 | Catalytica, Inc. | Process for preparing biaryl compounds |
| EP1034164B1 (de) * | 1997-11-24 | 2004-05-19 | Merck & Co., Inc. | Beta-alanin-derivate als zell-adhäsions-inhibitoren |
| US6645939B1 (en) | 1997-11-24 | 2003-11-11 | Merck & Co., Inc. | Substituted β-alanine derivatives as cell adhesion inhibitors |
| MY153569A (en) * | 1998-01-20 | 2015-02-27 | Mitsubishi Tanabe Pharma Corp | Inhibitors of ?4 mediated cell adhesion |
| JP4350306B2 (ja) * | 1998-04-23 | 2009-10-21 | ノバルティス アクチエンゲゼルシャフト | エンドセリン変換酵素のチオール型阻害剤 |
| JP2002512957A (ja) * | 1998-04-27 | 2002-05-08 | スミスクライン・ビーチャム・コーポレイション | Ｃｃｒ−３受容体アンタゴニスト |
| JP2000212185A (ja) | 1999-01-14 | 2000-08-02 | Ajinomoto Co Inc | パラボロノフェニルアラニン誘導体の製造方法 |
| WO2000043372A1 (en) | 1999-01-22 | 2000-07-27 | Elan Pharmaceuticals, Inc. | Acyl derivatives which treat vla-4 related disorders |
| KR20000065816A (ko) * | 1999-04-09 | 2000-11-15 | 성재갑 | 파라 및/또는 메타-치환 시아노페닐알라닌 유도체의 새로운 합성방법 |
| JP2003502314A (ja) | 1999-06-14 | 2003-01-21 | イーライ・リリー・アンド・カンパニー | 化合物 |
| GB9929552D0 (en) | 1999-12-14 | 2000-02-09 | Proteus Molecular Design | Compounds |
| AU5413600A (en) | 1999-06-14 | 2001-01-02 | Eli Lilly And Company | Compounds |
| JP3795305B2 (ja) | 1999-07-19 | 2006-07-12 | 田辺製薬株式会社 | 医薬組成物 |
| WO2001012183A1 (en) | 1999-08-16 | 2001-02-22 | Merck & Co., Inc. | Heterocycle amides as cell adhesion inhibitors |
| AU6909300A (en) | 1999-08-20 | 2001-03-19 | Merck & Co., Inc. | Substituted ureas as cell adhesion inhibitors |
| ATE355269T1 (de) | 1999-11-18 | 2006-03-15 | Ajinomoto Kk | Phenylalaninderivate |
| US6455539B2 (en) | 1999-12-23 | 2002-09-24 | Celltech R&D Limited | Squaric acid derivates |
| US20030199571A1 (en) | 1999-12-24 | 2003-10-23 | Gordon Bruton | (Hetero) Bicyclymethanesulfonylamino-substituted hydroxamic acid derivatives |
| JP2001212185A (ja) | 2000-02-02 | 2001-08-07 | Yasutaka Matsuo | 排便装置付ベッド |
| WO2001071572A2 (en) | 2000-03-22 | 2001-09-27 | Sidestep, Inc. | Method and apparatus for dynamic information connection engine |
| JP4748911B2 (ja) | 2000-04-05 | 2011-08-17 | シェーリング コーポレイション | Ｎ−環状ｐ２部分を含むｃ型肝炎ウイルスの大環状ｎｓ３‐セリンプロテアーゼ阻害剤 |
| US6482840B2 (en) | 2000-05-22 | 2002-11-19 | Merck & Co., Inc. | Substituted cyclic amidine derivatives as inhibitors of cell adhesion |
| GB0030306D0 (en) * | 2000-12-13 | 2001-01-24 | Lilly Co Eli | Compounds |
| GB0030305D0 (en) | 2000-12-13 | 2001-01-24 | Lilly Co Eli | Compounds |
| US6403584B1 (en) * | 2000-06-22 | 2002-06-11 | Merck & Co., Inc. | Substituted nipecotyl derivatives as inhibitors of cell adhesion |
| EP1303485A1 (de) | 2000-07-19 | 2003-04-23 | F. Hoffmann-La Roche Ag | Pyrrolidin-derivate als endothelin konvertierende enzyminhibitoren |
| AU2002239454A1 (en) | 2000-11-01 | 2002-05-27 | Millennium Pharmaceuticals, Inc. | Ace-2 modulating compounds and use thereof |
-
2003
- 2003-03-04 DE DE60336986T patent/DE60336986D1/de not_active Expired - Lifetime
- 2003-03-04 EP EP03743573A patent/EP1481967B1/de not_active Expired - Lifetime
- 2003-03-04 EP EP09015776.9A patent/EP2161254B1/de not_active Expired - Lifetime
- 2003-03-04 WO PCT/JP2003/002460 patent/WO2003074478A1/ja active Application Filing
-
2004
- 2004-02-10 US US10/774,498 patent/US7271280B2/en active Active
-
2007
- 2007-07-27 US US11/878,820 patent/US7714157B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7714157B2 (en) | 2010-05-11 |
| WO2003074478A1 (fr) | 2003-09-12 |
| US20070270603A1 (en) | 2007-11-22 |
| US7271280B2 (en) | 2007-09-18 |
| EP1481967B1 (de) | 2011-05-04 |
| EP1481967A4 (de) | 2007-01-31 |
| US20040158093A1 (en) | 2004-08-12 |
| EP2161254B1 (de) | 2014-08-13 |
| EP1481967A1 (de) | 2004-12-01 |
| EP2161254A1 (de) | 2010-03-10 |
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