NO20072872L - Kjemisk prosess - Google Patents

Kjemisk prosess

Info

Publication number
NO20072872L
NO20072872L NO20072872A NO20072872A NO20072872L NO 20072872 L NO20072872 L NO 20072872L NO 20072872 A NO20072872 A NO 20072872A NO 20072872 A NO20072872 A NO 20072872A NO 20072872 L NO20072872 L NO 20072872L
Authority
NO
Norway
Prior art keywords
chemical process
intermediates
processes
compound
producing
Prior art date
Application number
NO20072872A
Other languages
English (en)
Inventor
Michael Butters
Paul Michael Murray
Evan William Snape
Steven Robert Lenger
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34130901&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20072872(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Publication of NO20072872L publication Critical patent/NO20072872L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

(I) En fremgangsmåte for dannelse av en forbindelse med formel (I) eller et farmasøytisk akseptabelt salt derav, via en Heck-reaksjon er beskrevet. Mellomprodukter anvendelige ved fremgangsmåten og fremgangsmåtene for fremstilling av nevnte mellomprodukter er også beskrevet.
NO20072872A 2004-12-24 2007-06-06 Kjemisk prosess NO20072872L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0428328.9A GB0428328D0 (en) 2004-12-24 2004-12-24 Chemical process
PCT/GB2005/004999 WO2006067456A2 (en) 2004-12-24 2005-12-22 Process for preparing rosuvastatin

Publications (1)

Publication Number Publication Date
NO20072872L true NO20072872L (no) 2007-09-17

Family

ID=34130901

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20072872A NO20072872L (no) 2004-12-24 2007-06-06 Kjemisk prosess

Country Status (15)

Country Link
US (1) US8034932B2 (no)
EP (2) EP2361906A1 (no)
JP (1) JP5127460B2 (no)
KR (1) KR20070092307A (no)
CN (1) CN101084197B (no)
AU (1) AU2005317880B2 (no)
BR (1) BRPI0518647A2 (no)
CA (1) CA2589775A1 (no)
GB (1) GB0428328D0 (no)
IL (1) IL183528A (no)
MX (1) MX2007007777A (no)
NO (1) NO20072872L (no)
NZ (1) NZ555769A (no)
WO (1) WO2006067456A2 (no)
ZA (1) ZA200704535B (no)

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GB0324791D0 (en) * 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
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US7851624B2 (en) 2003-12-24 2010-12-14 Teva Pharamaceutical Industries Ltd. Triol form of rosuvastatin and synthesis of rosuvastatin
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GB0514078D0 (en) * 2005-07-08 2005-08-17 Astrazeneca Uk Ltd Chemical process
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EP1978020A1 (en) * 2007-04-03 2008-10-08 LEK Pharmaceuticals D.D. Processes for the preparation of statins, particularly rosuvastatin, and intermediates for the preparation thereof
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CN105669561B (zh) * 2014-11-19 2018-11-27 南京博优康远生物医药科技有限公司 一种4-(4-氟苯基)-5-烷氧基羰基-6-异丙基-3,4-二氢嘧啶-2(1h)-酮的制备方法
US10246423B2 (en) * 2015-01-23 2019-04-02 Centrient Pharmaceuticals Netherlands B.V. Process for preparing statin precursor
KR20160126700A (ko) 2015-04-24 2016-11-02 미래파인켐 주식회사 스타틴의 중간체, 이의 제조방법 및 이를 이용한 로수바스타틴의 제조방법

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Also Published As

Publication number Publication date
BRPI0518647A2 (pt) 2008-12-02
CN101084197A (zh) 2007-12-05
ZA200704535B (en) 2008-11-26
NZ555769A (en) 2010-01-29
US20080207903A1 (en) 2008-08-28
AU2005317880A1 (en) 2006-06-29
IL183528A0 (en) 2007-09-20
EP1871747A2 (en) 2008-01-02
CA2589775A1 (en) 2006-06-29
WO2006067456A3 (en) 2006-09-21
IL183528A (en) 2012-02-29
JP2008525407A (ja) 2008-07-17
US8034932B2 (en) 2011-10-11
KR20070092307A (ko) 2007-09-12
WO2006067456A2 (en) 2006-06-29
AU2005317880B2 (en) 2009-05-28
MX2007007777A (es) 2007-08-14
CN101084197B (zh) 2012-06-13
JP5127460B2 (ja) 2013-01-23
EP2361906A1 (en) 2011-08-31
GB0428328D0 (en) 2005-02-02

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