DE602004009716D1 - Verwendung von transthyretin als biomarker zum nachweis von kolorektalen adenomen; verfahren und nachweis-system - Google Patents
Verwendung von transthyretin als biomarker zum nachweis von kolorektalen adenomen; verfahren und nachweis-systemInfo
- Publication number
- DE602004009716D1 DE602004009716D1 DE602004009716T DE602004009716T DE602004009716D1 DE 602004009716 D1 DE602004009716 D1 DE 602004009716D1 DE 602004009716 T DE602004009716 T DE 602004009716T DE 602004009716 T DE602004009716 T DE 602004009716T DE 602004009716 D1 DE602004009716 D1 DE 602004009716D1
- Authority
- DE
- Germany
- Prior art keywords
- colorectal
- transthyretin
- detection
- biomarker
- directed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57419—Specifically defined cancers of colon
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/76—Assays involving albumins other than in routine use for blocking surfaces or for anchoring haptens during immunisation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Steroid Compounds (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2004/009124 WO2006015616A1 (en) | 2004-08-13 | 2004-08-13 | Use of transthyretin as a biomarker for colorectal adenoma and/or carcinoma; method for detection and test system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE602004009716D1 true DE602004009716D1 (de) | 2007-12-06 |
| DE602004009716T2 DE602004009716T2 (de) | 2008-08-28 |
Family
ID=34958684
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004009716T Active DE602004009716T2 (de) | 2004-08-13 | 2004-08-13 | Verwendung von transthyretin als biomarker zum nachweis von kolorektalen adenomen; verfahren und nachweis-system |
| DE602005012108T Active DE602005012108D1 (de) | 2004-08-13 | 2005-08-11 | Verwendung von c3a und derivaten als biomarker für kolorektaladenom und/oder -karzinom ; nachweisverfahren und testsystem damit |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602005012108T Active DE602005012108D1 (de) | 2004-08-13 | 2005-08-11 | Verwendung von c3a und derivaten als biomarker für kolorektaladenom und/oder -karzinom ; nachweisverfahren und testsystem damit |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7951528B2 (de) |
| EP (3) | EP1843159A1 (de) |
| JP (2) | JP4916441B2 (de) |
| KR (1) | KR20070051328A (de) |
| CN (2) | CN101014859A (de) |
| AT (2) | ATE376674T1 (de) |
| AU (2) | AU2004322162B2 (de) |
| BR (1) | BRPI0419002A (de) |
| CA (2) | CA2577601A1 (de) |
| DE (2) | DE602004009716T2 (de) |
| DK (2) | DK1761779T3 (de) |
| ES (2) | ES2295907T3 (de) |
| IL (2) | IL181131A (de) |
| MX (2) | MX2007001479A (de) |
| NO (2) | NO20070599L (de) |
| PL (2) | PL1761779T3 (de) |
| PT (2) | PT1761779E (de) |
| SI (1) | SI1776587T1 (de) |
| WO (2) | WO2006015616A1 (de) |
| ZA (1) | ZA200701188B (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE376674T1 (de) | 2004-08-13 | 2007-11-15 | Indivumed Gmbh | Verwendung von transthyretin als biomarker zum nachweis von kolorektalen adenomen; verfahren und nachweis-system |
| EP1775590A1 (de) * | 2005-10-11 | 2007-04-18 | Laboratorios S.A.L.V.A.T., S.A. | Nicht invasive in vitro Methode zur Detektion von Transitionalzellkarzinomen der Harnblase |
| JP4748671B2 (ja) * | 2006-03-16 | 2011-08-17 | 日東紡績株式会社 | 食道扁平上皮癌マーカーおよびそれを利用した食道扁平上皮癌の判定方法 |
| KR100819122B1 (ko) | 2006-09-30 | 2008-04-04 | 남명진 | 췌장암 진단용 키트 |
| WO2009025080A1 (ja) * | 2007-08-18 | 2009-02-26 | School Juridical Person Kitasato Institute | 大腸癌マーカポリペプチド、及び大腸癌の診断方法 |
| JP5203687B2 (ja) * | 2007-12-12 | 2013-06-05 | シスメックス株式会社 | 動物検査情報提供システム、中央装置、動物検査情報提供方法及びコンピュータプログラム |
| CN101838683B (zh) * | 2008-12-12 | 2013-09-18 | 深圳华大基因科技有限公司 | 一种kras基因和/或braf基因的核苷酸突变位点的检测方法 |
| CN102147396B (zh) * | 2010-02-10 | 2014-01-01 | 桑建利 | 人血液样本中脂类分子含量测定及其结直肠腺瘤诊断试剂盒制备与应用 |
| JP2013253780A (ja) * | 2010-10-12 | 2013-12-19 | Katakura Industries Co Ltd | うつ病の診断のためのデータの提供方法 |
| US10158898B2 (en) | 2012-07-26 | 2018-12-18 | Comcast Cable Communications, Llc | Customized options for consumption of content |
| CN104969071B (zh) * | 2012-11-30 | 2019-09-03 | 迪森德克斯公司 | 用于评估结肠肿瘤的存在或风险的方法 |
| CN104056277B (zh) * | 2013-03-21 | 2019-07-05 | 中国人民解放军第二军医大学 | Mlh1基因或其表达产物在dkk4高表达的结直肠癌中的应用 |
| CN106461647A (zh) * | 2014-03-28 | 2017-02-22 | 应用蛋白质组学公司 | 用于检测结肠直肠肿瘤的蛋白质生物标志物谱 |
| CN107110865B (zh) * | 2014-08-22 | 2020-01-10 | 雅培制药有限公司 | 用于结肠直肠癌的早期检测的方法 |
| CN105988006A (zh) * | 2015-02-10 | 2016-10-05 | 张曼 | 尿液补体c3蛋白的应用 |
| WO2016164815A1 (en) | 2015-04-10 | 2016-10-13 | Applied Proteomics, Inc. | Protein biomarker panels for detecting colorectal cancer and advanced adenoma |
| US20180092874A1 (en) * | 2016-10-03 | 2018-04-05 | Lincoln Memorial University | Identification and use of very long chain dicarboxylic acids for disease diagnosis, chemoprevention, and treatment |
| KR102018205B1 (ko) * | 2017-07-24 | 2019-09-05 | (주) 바이오인프라생명과학 | 대장암 진단용 조성물 및 상기 조성물을 이용한 대장암 진단 방법 |
| GB201721569D0 (en) * | 2017-12-21 | 2018-02-07 | Belgian Volition Sprl | Method for the detection and treatment of colorectal adenomas |
| GB201808476D0 (en) * | 2018-05-23 | 2018-07-11 | Univ Liverpool | Biomarkers for colorectal cancer |
| WO2023282916A1 (en) | 2021-07-09 | 2023-01-12 | Guardant Health, Inc. | Methods of detecting genomic rearrangements using cell free nucleic acids |
| CN116449018B (zh) * | 2023-02-14 | 2023-09-05 | 浙江大学 | 一种用于肠腺瘤腺癌诊断的血浆蛋白标记物及应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4996298A (en) * | 1988-04-20 | 1991-02-26 | New England Deaconess Hospital Corporation | Marker for colorectal carcinoma and methods of detecting the same |
| US5654161A (en) | 1995-05-12 | 1997-08-05 | Chiron Diagnostics Corporation | Method for diagnosing prostate cancer |
| US6221621B1 (en) | 1997-03-06 | 2001-04-24 | Bard Diagnostic Sciences, Inc. | Methods of screening for colorectal cancers in which a complement Factor I or related protein is associated |
| DE19711111C2 (de) | 1997-03-06 | 1999-09-02 | Schering Ag | In vitro Nachweis zur Erkennung von Darmtumoren |
| IL121134A0 (en) | 1997-06-22 | 1997-11-20 | Yeda Res & Dev | Peptides and antiallergic compositions comprising them |
| US20020160394A1 (en) | 2001-01-24 | 2002-10-31 | Bayer Corporation | Regulation of transthyretin to treat obesity |
| WO2003000182A2 (en) | 2001-06-22 | 2003-01-03 | Merck & Co., Inc. | Ppar-alpha ligands for the treatment or prevention of cachexia |
| US7144708B2 (en) * | 2001-06-25 | 2006-12-05 | The Cleveland Clinic Foundation | Markers of blood barrier disruption and methods of using same |
| DE10224534A1 (de) | 2002-05-31 | 2003-12-11 | Juergen Dolderer | Verfahren zum Diagnostizieren des colorektaien Karzinoms in einer Gewebeprobe und Mittel zur Behandlung |
| JP2005529625A (ja) | 2002-06-19 | 2005-10-06 | オンコセラピー・サイエンス株式会社 | 結腸直腸腫瘍の診断のための方法 |
| CN101692090B (zh) * | 2002-08-06 | 2014-06-25 | 约翰霍普金斯大学 | 用于检测卵巢癌的生物标记的用途 |
| WO2004090550A2 (en) * | 2003-04-08 | 2004-10-21 | Colotech A/S | A method for detection of colorectal cancer in human samples |
| WO2005008251A2 (en) | 2003-07-11 | 2005-01-27 | Praecis Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of endometriosis |
| ATE376674T1 (de) | 2004-08-13 | 2007-11-15 | Indivumed Gmbh | Verwendung von transthyretin als biomarker zum nachweis von kolorektalen adenomen; verfahren und nachweis-system |
| ES2334671T3 (es) | 2004-08-13 | 2010-03-15 | Egomedical Technologies Ag | Sistema de ensayo de analitos para determinar la concentracion de un analito en un fluido fisiologico o acuoso. |
| US9075062B2 (en) | 2005-03-22 | 2015-07-07 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Identification of biomarkers by serum protein profiling |
-
2004
- 2004-08-13 AT AT04764118T patent/ATE376674T1/de active
- 2004-08-13 EP EP07014481A patent/EP1843159A1/de not_active Withdrawn
- 2004-08-13 DK DK04764118T patent/DK1761779T3/da active
- 2004-08-13 BR BRPI0419002-5A patent/BRPI0419002A/pt not_active IP Right Cessation
- 2004-08-13 MX MX2007001479A patent/MX2007001479A/es unknown
- 2004-08-13 CN CNA2004800437997A patent/CN101014859A/zh active Pending
- 2004-08-13 PT PT04764118T patent/PT1761779E/pt unknown
- 2004-08-13 ES ES04764118T patent/ES2295907T3/es active Active
- 2004-08-13 JP JP2007525176A patent/JP4916441B2/ja not_active Expired - Fee Related
- 2004-08-13 EP EP04764118A patent/EP1761779B1/de not_active Not-in-force
- 2004-08-13 CA CA002577601A patent/CA2577601A1/en not_active Abandoned
- 2004-08-13 WO PCT/EP2004/009124 patent/WO2006015616A1/en active IP Right Grant
- 2004-08-13 DE DE602004009716T patent/DE602004009716T2/de active Active
- 2004-08-13 AU AU2004322162A patent/AU2004322162B2/en not_active Ceased
- 2004-08-13 US US11/660,070 patent/US7951528B2/en not_active Expired - Fee Related
- 2004-08-13 PL PL04764118T patent/PL1761779T3/pl unknown
-
2005
- 2005-08-11 WO PCT/EP2005/008742 patent/WO2006053592A1/en active Application Filing
- 2005-08-11 CN CNA2005800276025A patent/CN101014861A/zh active Pending
- 2005-08-11 ZA ZA200701188A patent/ZA200701188B/xx unknown
- 2005-08-11 AU AU2005306103A patent/AU2005306103A1/en not_active Abandoned
- 2005-08-11 PT PT05772471T patent/PT1776587E/pt unknown
- 2005-08-11 DK DK05772471T patent/DK1776587T3/da active
- 2005-08-11 DE DE602005012108T patent/DE602005012108D1/de active Active
- 2005-08-11 PL PL05772471T patent/PL1776587T3/pl unknown
- 2005-08-11 SI SI200530641T patent/SI1776587T1/sl unknown
- 2005-08-11 ES ES05772471T patent/ES2322378T3/es active Active
- 2005-08-11 MX MX2007001254A patent/MX2007001254A/es active IP Right Grant
- 2005-08-11 KR KR1020077005868A patent/KR20070051328A/ko not_active Application Discontinuation
- 2005-08-11 US US11/660,066 patent/US7883842B2/en not_active Expired - Fee Related
- 2005-08-11 AT AT05772471T patent/ATE419534T1/de active
- 2005-08-11 EP EP05772471A patent/EP1776587B9/de not_active Not-in-force
- 2005-08-11 JP JP2007525256A patent/JP4592753B2/ja not_active Expired - Fee Related
- 2005-08-11 CA CA002576998A patent/CA2576998A1/en not_active Abandoned
-
2007
- 2007-01-31 NO NO20070599A patent/NO20070599L/no not_active Application Discontinuation
- 2007-01-31 NO NO20070598A patent/NO20070598L/no not_active Application Discontinuation
- 2007-02-01 IL IL181131A patent/IL181131A/en not_active IP Right Cessation
- 2007-02-01 IL IL181132A patent/IL181132A/en not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8363 | Opposition against the patent |