ATE548656T1 - Verfahren zur identifizierung von patienten mit erhöhter wahrscheinlichkeit des auftretens eines ovarialkarzinoms und zusammensetzungen dafür - Google Patents
Verfahren zur identifizierung von patienten mit erhöhter wahrscheinlichkeit des auftretens eines ovarialkarzinoms und zusammensetzungen dafürInfo
- Publication number
- ATE548656T1 ATE548656T1 AT07717460T AT07717460T ATE548656T1 AT E548656 T1 ATE548656 T1 AT E548656T1 AT 07717460 T AT07717460 T AT 07717460T AT 07717460 T AT07717460 T AT 07717460T AT E548656 T1 ATE548656 T1 AT E548656T1
- Authority
- AT
- Austria
- Prior art keywords
- identifying patients
- occurring
- biomarkers
- biomarker
- expression
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 7
- 201000009030 Carcinoma Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000000090 biomarker Substances 0.000 abstract 6
- 230000014509 gene expression Effects 0.000 abstract 3
- 238000012216 screening Methods 0.000 abstract 3
- 206010033128 Ovarian cancer Diseases 0.000 abstract 2
- 206010061535 Ovarian neoplasm Diseases 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 2
- 102000004240 Glycodelin Human genes 0.000 abstract 1
- 108010081520 Glycodelin Proteins 0.000 abstract 1
- 238000007899 nucleic acid hybridization Methods 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 230000002018 overexpression Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76276006P | 2006-01-27 | 2006-01-27 | |
| PCT/US2007/061205 WO2007090076A2 (en) | 2006-01-27 | 2007-01-29 | Methods for identifying patients with an increased likelihood of having ovarian cancer and compositions therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE548656T1 true ATE548656T1 (de) | 2012-03-15 |
Family
ID=38328113
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07717460T ATE548656T1 (de) | 2006-01-27 | 2007-01-29 | Verfahren zur identifizierung von patienten mit erhöhter wahrscheinlichkeit des auftretens eines ovarialkarzinoms und zusammensetzungen dafür |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20070212721A1 (de) |
| EP (2) | EP1987360B1 (de) |
| JP (1) | JP2009524438A (de) |
| KR (1) | KR20080094803A (de) |
| CN (1) | CN101410715A (de) |
| AT (1) | ATE548656T1 (de) |
| AU (1) | AU2007211085A1 (de) |
| BR (1) | BRPI0707249A2 (de) |
| CA (1) | CA2637446A1 (de) |
| MX (1) | MX2008009592A (de) |
| WO (1) | WO2007090076A2 (de) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7741019B2 (en) * | 2000-11-01 | 2010-06-22 | Mount Sinai Hospital | Detection of ovarian cancer |
| US10533998B2 (en) | 2008-07-18 | 2020-01-14 | Bio-Rad Laboratories, Inc. | Enzyme quantification |
| GB0307403D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Selection by compartmentalised screening |
| US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
| GB0307428D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
| US20050221339A1 (en) | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
| US7968287B2 (en) | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
| EP3913375A1 (de) | 2006-01-11 | 2021-11-24 | Bio-Rad Laboratories, Inc. | Mikrofluidische vorrichtungen und verfahren zur verwendung bei der bildung und steuerung von nanoreaktoren |
| JP2009526519A (ja) * | 2006-01-17 | 2009-07-23 | セルーメン、インコーポレイテッド | 生物学的システム応答の予測方法 |
| EP2021113A2 (de) | 2006-05-11 | 2009-02-11 | Raindance Technologies, Inc. | Mikrofluidische vorrichtungen |
| US9562837B2 (en) | 2006-05-11 | 2017-02-07 | Raindance Technologies, Inc. | Systems for handling microfludic droplets |
| CN101484806A (zh) | 2006-05-17 | 2009-07-15 | 协乐民公司 | 一种对组织进行自动分析的方法 |
| BRPI0711011A2 (pt) | 2006-05-18 | 2011-08-23 | Molecular Profiling Inst Inc | método para a determinação da intervenção médica para um estado de doença, método para a identificação de uma terapia de droga com capacidade de interação com um alvo molecular e sistema para a determinação da intervenção médica individualizada para um estado de doença |
| US8768629B2 (en) | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
| US20100009352A1 (en) * | 2006-05-24 | 2010-01-14 | Gough Albert H | Method for Modeling a Disease |
| US9012390B2 (en) | 2006-08-07 | 2015-04-21 | Raindance Technologies, Inc. | Fluorocarbon emulsion stabilizing surfactants |
| US20100112602A1 (en) * | 2006-11-10 | 2010-05-06 | Taylor Lansing D | Protein-Protein Interaction Biosensors and Methods of Use Thereof |
| US8772046B2 (en) | 2007-02-06 | 2014-07-08 | Brandeis University | Manipulation of fluids and reactions in microfluidic systems |
| KR20100015438A (ko) * | 2007-03-09 | 2010-02-12 | 트리패스 이미징, 인코포레이티드 | He4 모노클로날 항체 및 이의 사용 방법 |
| WO2008130623A1 (en) | 2007-04-19 | 2008-10-30 | Brandeis University | Manipulation of fluids, fluid components and reactions in microfluidic systems |
| US20090087849A1 (en) * | 2007-09-06 | 2009-04-02 | Tripath Imaging, Inc. | Nucleic acid-based methods and compositions for the detection of ovarian cancer |
| US20090130195A1 (en) * | 2007-10-17 | 2009-05-21 | Mildred Acevedo-Duncan | Prostate carcinogenesis predictor |
| EP2088204A1 (de) * | 2008-02-05 | 2009-08-12 | Adnagen AG | Verfahren und Kit zur Diagnose bzw. Kontrolle der Behandlung von Ovarialkarzinomen |
| US12038438B2 (en) | 2008-07-18 | 2024-07-16 | Bio-Rad Laboratories, Inc. | Enzyme quantification |
| WO2010009365A1 (en) | 2008-07-18 | 2010-01-21 | Raindance Technologies, Inc. | Droplet libraries |
| US10359425B2 (en) | 2008-09-09 | 2019-07-23 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| AU2009302537A1 (en) * | 2008-10-06 | 2010-04-15 | Somalogic, Inc. | Ovarian cancer biomarkers and uses thereof |
| US20100221752A2 (en) * | 2008-10-06 | 2010-09-02 | Somalogic, Inc. | Ovarian Cancer Biomarkers and Uses Thereof |
| CA2750155A1 (en) * | 2008-12-30 | 2010-07-08 | Centocor Ortho Biotech Inc. | Serum markers predicting clinical response to anti-tnf.alpha. antibodiesin patients with ankylosing spondylitis |
| WO2010102167A1 (en) | 2009-03-05 | 2010-09-10 | Becton, Dickinson And Company | Matrix metalloproteinase-7 (mmp-7) monoclonal antibodies and methods for their use in the detection of ovarian cancer |
| AU2010221188A1 (en) * | 2009-03-06 | 2011-10-20 | Tripath Imaging, Inc. | Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer |
| WO2010111231A1 (en) | 2009-03-23 | 2010-09-30 | Raindance Technologies, Inc. | Manipulation of microfluidic droplets |
| WO2011042564A1 (en) | 2009-10-09 | 2011-04-14 | Universite De Strasbourg | Labelled silica-based nanomaterial with enhanced properties and uses thereof |
| EP2517025B1 (de) | 2009-12-23 | 2019-11-27 | Bio-Rad Laboratories, Inc. | Verfahren zur reduzierung des austauschs von molekülen zwischen tröpfchen |
| WO2011100453A2 (en) * | 2010-02-10 | 2011-08-18 | Maine Medical Center | Compositions and methods for the treatment of cardiac and vascular disease |
| US9366632B2 (en) | 2010-02-12 | 2016-06-14 | Raindance Technologies, Inc. | Digital analyte analysis |
| US9399797B2 (en) | 2010-02-12 | 2016-07-26 | Raindance Technologies, Inc. | Digital analyte analysis |
| US10351905B2 (en) | 2010-02-12 | 2019-07-16 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| EP4484577A3 (de) | 2010-02-12 | 2025-03-26 | Bio-Rad Laboratories, Inc. | Digitale analytanalyse |
| MX355020B (es) | 2010-07-09 | 2018-04-02 | Somalogic Inc | Biomarcadores de cancer de pulmon y usos de los mismos. |
| JP5931874B2 (ja) | 2010-08-13 | 2016-06-08 | ソマロジック・インコーポレーテッド | 膵癌バイオマーカーおよびその使用 |
| EP2622103B2 (de) | 2010-09-30 | 2022-11-16 | Bio-Rad Laboratories, Inc. | Sandwichassays in tröpfchen |
| AU2011352167A1 (en) * | 2010-12-28 | 2013-07-11 | Caris Mpi, Inc. | Molecular profiling for cancer |
| WO2012109600A2 (en) | 2011-02-11 | 2012-08-16 | Raindance Technologies, Inc. | Methods for forming mixed droplets |
| CA2827618C (en) | 2011-02-17 | 2019-08-06 | Fujirebio Diagnostics, Inc. | Compositions and methods of use for the determination of he4a |
| US9150852B2 (en) | 2011-02-18 | 2015-10-06 | Raindance Technologies, Inc. | Compositions and methods for molecular labeling |
| CN103582815A (zh) * | 2011-02-24 | 2014-02-12 | 佛米利昂公司 | 用于卵巢癌的生物标志物组、诊断方法和测试试剂盒 |
| CA2830501C (en) | 2011-03-17 | 2023-10-17 | Cernostics, Inc. | Systems and compositions for diagnosing barrett's esophagus and methods of using the same |
| CN102735840B (zh) * | 2011-04-13 | 2014-06-04 | 中国医学科学院肿瘤研究所 | 用于诊断或筛查卵巢癌的试剂 |
| WO2012142330A1 (en) * | 2011-04-15 | 2012-10-18 | Brown University | Micro rnas as diagnostic biomarkers and therapeutics for ovarian cancer and metastatic tumors that disseminate within the peritoneal cavity |
| BR112013031019A2 (pt) * | 2011-06-02 | 2017-03-21 | Almac Diagnostics Ltd | teste diagnóstico molecular para câncer |
| US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
| WO2012174569A2 (en) * | 2011-06-17 | 2012-12-20 | The Board Of Trustees Of The University Of Arkansas | New markers for early diagnosis of ovarian cancer, monitoring during therapy, and new therapy options during and after chematherapy |
| US8658430B2 (en) | 2011-07-20 | 2014-02-25 | Raindance Technologies, Inc. | Manipulating droplet size |
| WO2013120089A1 (en) | 2012-02-10 | 2013-08-15 | Raindance Technologies, Inc. | Molecular diagnostic screening assay |
| WO2013165748A1 (en) | 2012-04-30 | 2013-11-07 | Raindance Technologies, Inc | Digital analyte analysis |
| CN103575902B (zh) * | 2012-08-03 | 2015-07-29 | 河南生生医疗器械有限公司 | 一种时间分辨荧光法四项综合检测卵巢癌试剂盒及其应用 |
| US11091809B2 (en) | 2012-12-03 | 2021-08-17 | Almac Diagnostic Services Limited | Molecular diagnostic test for cancer |
| CA2907504C (en) * | 2013-03-27 | 2023-01-17 | Theranos, Inc. | Methods, devices, and systems for sample analysis |
| EP2986762B1 (de) | 2013-04-19 | 2019-11-06 | Bio-Rad Laboratories, Inc. | Digitale analyse von analyten |
| CN105745543B (zh) * | 2013-09-18 | 2018-02-02 | 阿德莱德研究及创新控股有限公司 | 卵巢癌的自身抗体生物标志物 |
| US11901041B2 (en) | 2013-10-04 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Digital analysis of nucleic acid modification |
| US11221327B2 (en) * | 2013-10-10 | 2022-01-11 | Mcmaster University | Method for diagnosing and monitoring inflammatory disease progression |
| CN103525941A (zh) * | 2013-10-29 | 2014-01-22 | 上海市奉贤区中心医院 | Cthrc1基因在制备检测/治疗宫颈癌药物中的应用 |
| US9944977B2 (en) | 2013-12-12 | 2018-04-17 | Raindance Technologies, Inc. | Distinguishing rare variations in a nucleic acid sequence from a sample |
| US11193176B2 (en) | 2013-12-31 | 2021-12-07 | Bio-Rad Laboratories, Inc. | Method for detecting and quantifying latent retroviral RNA species |
| GB201409479D0 (en) | 2014-05-28 | 2014-07-09 | Almac Diagnostics Ltd | Molecular diagnostic test for cancer |
| CN106290892A (zh) * | 2015-06-26 | 2017-01-04 | 上海市肿瘤研究所 | Cthrc1在肝硬化诊断和治疗中的应用 |
| US10647981B1 (en) | 2015-09-08 | 2020-05-12 | Bio-Rad Laboratories, Inc. | Nucleic acid library generation methods and compositions |
| US10962544B2 (en) | 2015-11-25 | 2021-03-30 | Cernostics, Inc. | Methods of predicting progression of Barrett's esophagus |
| US20190064172A1 (en) * | 2016-04-20 | 2019-02-28 | Eisai Inc. | Prognosis of serous ovarian cancer using biomarkers |
| GB2594002B (en) * | 2016-06-24 | 2022-04-13 | Univ South Carolina | Inhibin as targetable regulators of angiogenesis |
| WO2018009811A1 (en) * | 2016-07-08 | 2018-01-11 | Genentech, Inc. | Use of human epididymis protein 4 (he4) for assessing responsiveness of muc 16-positive cancer treatment |
| CN109844532B (zh) * | 2016-08-10 | 2022-06-17 | 米密德诊断学有限公司 | 分析生物数据的系统和方法 |
| CN106520924A (zh) * | 2016-10-14 | 2017-03-22 | 浙江大学 | 一种用于检测卵巢癌的引物组及检测方法 |
| US10998178B2 (en) | 2017-08-28 | 2021-05-04 | Purdue Research Foundation | Systems and methods for sample analysis using swabs |
| CN109480771B (zh) * | 2018-10-17 | 2021-09-07 | 江西惠肽生物科技有限公司 | 一种卵巢肿块良恶的确定方法及确定装置 |
| CN112946290A (zh) * | 2019-12-10 | 2021-06-11 | 上海交通大学医学院附属仁济医院 | 细胞外基质底物反应蛋白1在制备诊断和预测卵巢癌试剂中的应用 |
| KR102316178B1 (ko) * | 2020-04-14 | 2021-10-22 | 서울대학교병원 | 난소암 환자의 암 재발율 또는 생존율 예측용 조성물 |
| CN111693703B (zh) * | 2020-07-17 | 2023-07-21 | 北京信诺卫康科技有限公司 | Spondin 1和HE4联合用作早期卵巢癌生物标志物以及试剂盒 |
| KR102472050B1 (ko) * | 2022-03-29 | 2022-11-30 | 주식회사 아이엠비디엑스 | 환자 맞춤형 패널을 이용한 암의 재발을 예측하는 방법 |
Family Cites Families (98)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ201918A (en) | 1981-09-18 | 1987-04-30 | Genentech Inc | N-terminal methionyl analogues of bovine growth hormone |
| US4708871A (en) | 1983-03-08 | 1987-11-24 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4873192A (en) | 1987-02-17 | 1989-10-10 | The United States Of America As Represented By The Department Of Health And Human Services | Process for site specific mutagenesis without phenotypic selection |
| US4921790A (en) * | 1987-04-24 | 1990-05-01 | Research Corporation | Tumor specific assay for CA125 ovarian cancer antigen |
| US4843155A (en) | 1987-11-19 | 1989-06-27 | Piotr Chomczynski | Product and process for isolating RNA |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| EP1997891A1 (de) | 1988-09-02 | 2008-12-03 | Dyax Corporation | Herstellung und Auswahl von Rekombinantproteinen mit verschiedenen Bindestellen |
| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| US6040138A (en) | 1995-09-15 | 2000-03-21 | Affymetrix, Inc. | Expression monitoring by hybridization to high density oligonucleotide arrays |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| AU665190B2 (en) | 1990-07-10 | 1995-12-21 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| WO1992009690A2 (en) | 1990-12-03 | 1992-06-11 | Genentech, Inc. | Enrichment method for variant proteins with altered binding properties |
| ATE439435T1 (de) | 1991-03-01 | 2009-08-15 | Dyax Corp | Chimäres protein mit mikroprotein mit zwei oder mehr disulfidbindungen und ausgestaltungen davon |
| DE69233750D1 (de) | 1991-04-10 | 2009-01-02 | Scripps Research Inst | Bibliotheken heterodimerer Rezeptoren mittels Phagemiden |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| CA2118806A1 (en) | 1991-09-18 | 1993-04-01 | William J. Dower | Method of synthesizing diverse collections of oligomers |
| AU675054B2 (en) | 1991-11-22 | 1997-01-23 | Affymetrix, Inc. | Combinatorial strategies for polymer synthesis |
| US5384261A (en) | 1991-11-22 | 1995-01-24 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis using mechanically directed flow paths |
| US5976818A (en) * | 1991-12-16 | 1999-11-02 | The Board Of Trustees Of The University Of Arkansas | Monoclonal antibodies which identify the glycoprotein carrying the CA 125 epitope |
| US5556752A (en) | 1994-10-24 | 1996-09-17 | Affymetrix, Inc. | Surface-bound, unimolecular, double-stranded DNA |
| US5545531A (en) | 1995-06-07 | 1996-08-13 | Affymax Technologies N.V. | Methods for making a device for concurrently processing multiple biological chip assays |
| US5856174A (en) | 1995-06-29 | 1999-01-05 | Affymetrix, Inc. | Integrated nucleic acid diagnostic device |
| US5854033A (en) | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
| EP0880598A4 (de) | 1996-01-23 | 2005-02-23 | Affymetrix Inc | Verfahren zur analyse von nukleinsäure |
| IL135593A (en) | 1997-10-14 | 2004-06-01 | Luminex Corp | Precisely fluorescently painted polymeric microspheres and methods for making and using them |
| DE69829402T2 (de) | 1997-10-31 | 2006-04-13 | Affymetrix, Inc. (a Delaware Corp.), Santa Clara | Expressionsprofile in adulten und fötalen organen |
| CA2318779C (en) | 1998-01-22 | 2009-08-25 | Luminex Corporation | Microparticles with multiple fluorescent signals |
| US6020135A (en) | 1998-03-27 | 2000-02-01 | Affymetrix, Inc. | P53-regulated genes |
| US7223727B2 (en) * | 1998-04-09 | 2007-05-29 | Serono Genetics Institute S.A. | GSSP4 polynucleotides and polypeptides and uses thereof |
| US6783961B1 (en) * | 1999-02-26 | 2004-08-31 | Genset S.A. | Expressed sequence tags and encoded human proteins |
| US6592822B1 (en) | 1998-05-14 | 2003-07-15 | Luminex Corporation | Multi-analyte diagnostic system and computer implemented process for same |
| US20020039764A1 (en) * | 1999-03-12 | 2002-04-04 | Rosen Craig A. | Nucleic, acids, proteins, and antibodies |
| US20030064072A9 (en) * | 1999-03-12 | 2003-04-03 | Rosen Craig A. | Nucleic acids, proteins and antibodies |
| US20020052308A1 (en) * | 1999-03-12 | 2002-05-02 | Rosen Craig A. | Nucleic acids, proteins and antibodies |
| AU3395900A (en) * | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
| US20030040617A9 (en) * | 1999-03-12 | 2003-02-27 | Rosen Craig A. | Nucleic acids, proteins and antibodies |
| US20020151681A1 (en) * | 1999-03-12 | 2002-10-17 | Rosen Craig A. | Nucleic acids, proteins and antibodies |
| US20040009494A1 (en) * | 1999-08-11 | 2004-01-15 | Richard Murray | Novel methods of diagnosis of angiogenesis and other conditions, compositions, and the methods of screening for modulators |
| US20020019330A1 (en) * | 1999-08-11 | 2002-02-14 | Richard Murray | Novel methods of diagnosis of angiogenesis, compositions, and methods of screening for angiogenesis modulators |
| US20030152926A1 (en) * | 1999-08-11 | 2003-08-14 | Eos Biotechnology, Inc. | Novel methods of diagnosis of angiogenesis, compositions and methods of screening for angiogenesis modulators |
| US20020015970A1 (en) * | 1999-08-11 | 2002-02-07 | Richard Murray | Novel methods of diagnosis of angiogenesis, compositions, and methods of screening for angiogenesis modulators |
| US20020058292A1 (en) * | 2000-12-08 | 2002-05-16 | Dillon Davin C. | Ovarian tumor antigen and methods of use therefor |
| WO2001021653A2 (en) * | 1999-09-23 | 2001-03-29 | Corixa Corporation | Ovarian tumor antigen and methods of use therefor |
| US20020155468A1 (en) * | 1999-09-23 | 2002-10-24 | Corixa Corporation | Ovarian tumor antigen and methods of use therefor |
| US20020086330A1 (en) * | 2000-01-31 | 2002-07-04 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| US20020090615A1 (en) * | 2000-01-31 | 2002-07-11 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| US20020086823A1 (en) * | 2000-01-31 | 2002-07-04 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| US20030125246A9 (en) * | 2000-01-31 | 2003-07-03 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| US20020077270A1 (en) * | 2000-01-31 | 2002-06-20 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| US20020094953A1 (en) * | 2000-01-31 | 2002-07-18 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| US20020132753A1 (en) * | 2000-01-31 | 2002-09-19 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| US20030171252A9 (en) * | 2000-01-31 | 2003-09-11 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| US20030092611A9 (en) * | 2000-01-31 | 2003-05-15 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| US20020061521A1 (en) * | 2000-01-31 | 2002-05-23 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| US20020090674A1 (en) * | 2000-01-31 | 2002-07-11 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| US20040101927A9 (en) * | 2000-01-31 | 2004-05-27 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| US20040259152A1 (en) * | 2000-02-22 | 2004-12-23 | Richard Murray | Novel methods of diagnosing and screening for modulators of tissue remodeling and treating related diseases |
| WO2002009573A2 (en) * | 2000-07-31 | 2002-02-07 | The Brigham And Women's Hospital, Inc. | Prognostic classification of endometrial cancer |
| US20020045230A1 (en) * | 2000-08-14 | 2002-04-18 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| US6812339B1 (en) * | 2000-09-08 | 2004-11-02 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| US20070037165A1 (en) * | 2000-09-08 | 2007-02-15 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| US20020098497A1 (en) * | 2000-09-13 | 2002-07-25 | Si Lok | Use of human phermone polypeptides |
| AU2002241720A1 (en) * | 2000-11-08 | 2002-06-18 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of ovarian cancer |
| US20030087250A1 (en) * | 2001-03-14 | 2003-05-08 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer |
| US7309760B2 (en) * | 2001-04-17 | 2007-12-18 | The Board Of Trustees Of The University Of Arkansas | Repeat sequences of the CA125 gene and their use for diagnostic and therapeutic interventions |
| AU2002254615A1 (en) * | 2001-04-17 | 2002-10-28 | The Board Of Trustees Of The University Of Arkansas | Repeat sequences of the ca125 gene and their use for diagnostic and therapeutic interventions |
| IL158397A0 (en) * | 2001-04-18 | 2004-05-12 | Genset Sa | Polypeptides, their preparation and their use |
| US7205142B2 (en) * | 2001-05-11 | 2007-04-17 | Sloan-Kettering Institute For Cancer Research | Nucleic acid sequence encoding ovarian antigen, CA125, and uses thereof |
| WO2002092836A2 (en) * | 2001-05-11 | 2002-11-21 | Sloan-Kettering Institute For Cancer Research | Nucleic acid sequence encoding ovarian antigen, ca125, and uses thereof |
| US20070015144A9 (en) * | 2001-05-25 | 2007-01-18 | Genset, S.A. | Human cDNAs and proteins and uses thereof |
| AU2001286171B2 (en) * | 2001-05-25 | 2008-01-10 | Serono Genetics Institute S.A. | Human CDNAs and proteins and uses thereof |
| US7189507B2 (en) * | 2001-06-18 | 2007-03-13 | Pdl Biopharma, Inc. | Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer |
| US7705120B2 (en) * | 2001-06-21 | 2010-04-27 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer |
| US20040076955A1 (en) * | 2001-07-03 | 2004-04-22 | Eos Biotechnology, Inc. | Methods of diagnosis of bladder cancer, compositions and methods of screening for modulators of bladder cancer |
| US20040033495A1 (en) * | 2001-08-03 | 2004-02-19 | Eos Biotechnology, Inc. | Methods of diagnosis of angiogenesis, compositions and methods of screening for angiogenesis modulators |
| US7270960B2 (en) * | 2001-08-29 | 2007-09-18 | Pacific Northwest Research Institute | Diagnosis of ovarian carcinomas |
| US20030124579A1 (en) * | 2001-09-05 | 2003-07-03 | Eos Biotechnology, Inc. | Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer |
| US20070042360A1 (en) * | 2001-09-17 | 2007-02-22 | Eos Biotechnology, Inc. | Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer |
| US20030232350A1 (en) * | 2001-11-13 | 2003-12-18 | Eos Biotechnology, Inc. | Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer |
| EP1540010B8 (de) * | 2002-08-06 | 2010-07-14 | The Johns Hopkins University | Verwendung von biomarkern zum nachweis von eierstockkrebs |
| EP1570078A4 (de) * | 2002-10-04 | 2006-09-13 | Van Andel Res Inst | Molekulare subklassifizierung von nierentumoren und entdeckung neuer diagnostischer marker |
| US20050181375A1 (en) * | 2003-01-10 | 2005-08-18 | Natasha Aziz | Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of metastatic cancer |
| WO2004075713A2 (en) * | 2003-02-26 | 2004-09-10 | Mount Sinai Hospital | Multiple marker assay for detection of ovarian cancer |
| US20050208500A1 (en) * | 2003-03-04 | 2005-09-22 | Erlander Mark G | Signatures of ER status in breast cancer |
| US20050255114A1 (en) * | 2003-04-07 | 2005-11-17 | Nuvelo, Inc. | Methods and diagnosis for the treatment of preeclampsia |
| WO2004106495A2 (en) * | 2003-05-29 | 2004-12-09 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer |
| FR2855832B1 (fr) * | 2003-06-03 | 2007-09-14 | Biomerieux Sa | Procede de diagnostic et/ou de pronostic d'un syndrome septique |
| US20070037204A1 (en) * | 2003-08-08 | 2007-02-15 | Hiroyuki ABURANTAI | Gene overexpressed in cancer |
| EP1668360A4 (de) | 2003-08-15 | 2007-08-08 | Univ Pittsburgh | Multifaktor-krebsnachweistest |
| JP2007504463A (ja) * | 2003-09-05 | 2007-03-01 | ロイヤル ウィメンズ ホスピタル | 卵巣癌用の診断マーカー |
| MXPA06003402A (es) * | 2003-10-07 | 2006-06-27 | Millennium Pharm Inc | Moleculas de acidos nucleicos y proteinas para la identificacion, evaluacion, prevencion y tratamiento de cancer de ovario. |
| US7666583B2 (en) * | 2004-02-19 | 2010-02-23 | Yale University | Identification of cancer protein biomarkers using proteomic techniques |
| EP1766408A2 (de) * | 2004-07-09 | 2007-03-28 | Tripath Imaging, Inc. | Verfahren und zusammensetzungen zum nachweis von ovarialkarzinom |
| EP2982761B1 (de) * | 2006-01-04 | 2017-10-04 | Fujirebio America, Inc. | Verwendung von he4 und anderen biochemischen markern zur beurteilung von endometrium- und gebärmutterkrebs |
-
2007
- 2007-01-29 AU AU2007211085A patent/AU2007211085A1/en not_active Abandoned
- 2007-01-29 CA CA002637446A patent/CA2637446A1/en not_active Abandoned
- 2007-01-29 JP JP2008552607A patent/JP2009524438A/ja active Pending
- 2007-01-29 CN CNA200780011459XA patent/CN101410715A/zh active Pending
- 2007-01-29 AT AT07717460T patent/ATE548656T1/de active
- 2007-01-29 WO PCT/US2007/061205 patent/WO2007090076A2/en not_active Ceased
- 2007-01-29 US US11/699,229 patent/US20070212721A1/en not_active Abandoned
- 2007-01-29 MX MX2008009592A patent/MX2008009592A/es not_active Application Discontinuation
- 2007-01-29 EP EP07717460A patent/EP1987360B1/de not_active Not-in-force
- 2007-01-29 KR KR1020087021027A patent/KR20080094803A/ko not_active Withdrawn
- 2007-01-29 BR BRPI0707249-0A patent/BRPI0707249A2/pt not_active IP Right Cessation
- 2007-01-29 EP EP11159423A patent/EP2363711A1/de not_active Withdrawn
-
2008
- 2008-10-30 US US12/261,330 patent/US20090075307A1/en not_active Abandoned
- 2008-10-30 US US12/261,205 patent/US20090068690A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MX2008009592A (es) | 2008-09-08 |
| WO2007090076A3 (en) | 2007-11-08 |
| CN101410715A (zh) | 2009-04-15 |
| US20090068690A1 (en) | 2009-03-12 |
| AU2007211085A1 (en) | 2007-08-09 |
| JP2009524438A (ja) | 2009-07-02 |
| EP1987360B1 (de) | 2012-03-07 |
| EP2363711A1 (de) | 2011-09-07 |
| BRPI0707249A2 (pt) | 2011-04-26 |
| EP1987360A2 (de) | 2008-11-05 |
| US20090075307A1 (en) | 2009-03-19 |
| CA2637446A1 (en) | 2007-08-09 |
| WO2007090076A2 (en) | 2007-08-09 |
| WO2007090076A8 (en) | 2011-03-03 |
| KR20080094803A (ko) | 2008-10-24 |
| US20070212721A1 (en) | 2007-09-13 |
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