DE602004003056D1 - Polyenoxazole mit antitumorwirkung und verfahren zu deren herstellung mittels eines streptomyces-stamms - Google Patents

Polyenoxazole mit antitumorwirkung und verfahren zu deren herstellung mittels eines streptomyces-stamms

Info

Publication number
DE602004003056D1
DE602004003056D1 DE602004003056T DE602004003056T DE602004003056D1 DE 602004003056 D1 DE602004003056 D1 DE 602004003056D1 DE 602004003056 T DE602004003056 T DE 602004003056T DE 602004003056 T DE602004003056 T DE 602004003056T DE 602004003056 D1 DE602004003056 D1 DE 602004003056D1
Authority
DE
Germany
Prior art keywords
streptomyces
polyenoxazole
antitumoric
stem
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004003056T
Other languages
English (en)
Inventor
B Mcalpine
M Farnet
Emmanuel Zazopoulos
Nargis Ismail
O Bachmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thallion Pharmaceuticals Inc
Original Assignee
Ecopia Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ecopia Biosciences Inc filed Critical Ecopia Biosciences Inc
Publication of DE602004003056D1 publication Critical patent/DE602004003056D1/de
Anticipated expiration legal-status Critical
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/14—Nitrogen or oxygen as hetero atom and at least one other diverse hetero ring atom in the same ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C12R2001/60—Streptomyces sparsogenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
DE602004003056T 2003-06-13 2004-06-14 Polyenoxazole mit antitumorwirkung und verfahren zu deren herstellung mittels eines streptomyces-stamms Active DE602004003056D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47793103P 2003-06-13 2003-06-13
PCT/CA2004/000872 WO2004110439A1 (en) 2003-06-13 2004-06-14 Polyene oxazoles with antitumour activity and processes for their preparation using a streptomyces strain

Publications (1)

Publication Number Publication Date
DE602004003056D1 true DE602004003056D1 (de) 2006-12-14

Family

ID=33551785

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004003056T Active DE602004003056D1 (de) 2003-06-13 2004-06-14 Polyenoxazole mit antitumorwirkung und verfahren zu deren herstellung mittels eines streptomyces-stamms

Country Status (7)

Country Link
US (2) US7312339B2 (de)
EP (1) EP1633352B1 (de)
JP (1) JP2006527208A (de)
AT (1) ATE344032T1 (de)
CA (1) CA2470935A1 (de)
DE (1) DE602004003056D1 (de)
WO (1) WO2004110439A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102471238B (zh) * 2009-07-14 2014-04-02 高砂香料工业株式会社 千日菊素的制造方法及其制造中间体
CN107478670B (zh) * 2017-08-08 2018-04-03 中国环境科学研究院 一种沉积物中肌醇磷酸盐与腐殖酸相互作用的分析方法
CN112067647B (zh) * 2020-11-11 2021-01-15 东南大学 一种检测液体生物样本葡萄糖含量的弛豫核磁共振方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3364198A (en) * 1964-10-12 1968-01-16 Upjohn Co Process for the production of n6-methyltubercidin and intermediate
US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US4452775A (en) * 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
JPS6081184A (ja) * 1983-10-11 1985-05-09 Banyu Pharmaceut Co Ltd 抗腫瘍性抗生物質及びその製法
JPS61172881A (ja) * 1985-01-26 1986-08-04 Meiji Seika Kaisha Ltd 新抗生物質キューロマイシンａ又はｂとその製造法
US5039660A (en) * 1988-03-02 1991-08-13 Endocon, Inc. Partially fused peptide pellet
JPH08176116A (ja) * 1994-12-27 1996-07-09 Rikagaku Kenkyusho 新規抗生物質スパロキソマイシン
WO2001036048A1 (en) * 1999-11-15 2001-05-25 Parker Hughes Institute Phorboxazole derivatives for treating cancer

Also Published As

Publication number Publication date
JP2006527208A (ja) 2006-11-30
WO2004110439A1 (en) 2004-12-23
EP1633352B1 (de) 2006-11-02
US20050038090A1 (en) 2005-02-17
CA2470935A1 (en) 2004-12-13
EP1633352A1 (de) 2006-03-15
ATE344032T1 (de) 2006-11-15
US20090069396A1 (en) 2009-03-12
US7312339B2 (en) 2007-12-25

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