CY1119460T1 - Μεθοδοι διατηρησης της στοματικης υγειας σε ζωα χρησιμοποιωντας παραγωγα μορφολινης - Google Patents
Μεθοδοι διατηρησης της στοματικης υγειας σε ζωα χρησιμοποιωντας παραγωγα μορφολινηςInfo
- Publication number
- CY1119460T1 CY1119460T1 CY20171101075T CY171101075T CY1119460T1 CY 1119460 T1 CY1119460 T1 CY 1119460T1 CY 20171101075 T CY20171101075 T CY 20171101075T CY 171101075 T CY171101075 T CY 171101075T CY 1119460 T1 CY1119460 T1 CY 1119460T1
- Authority
- CY
- Cyprus
- Prior art keywords
- morpholine
- producers
- animals
- methods
- oral health
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Birds (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
Abstract
Χρήση μιας ένωσης η οποία έχει τον τύπο (I) στην παρασκευή ενός φαρμάκου για την πρόληψη ή αντιμετώπιση μιας νόσου η οποία προκαλείται από βακτήρια του στόματος σε ένα ζώο όπου R1 είναι μια γραμμική ή διακλαδισμένη αλκυλική ομάδα η οποία περιέχει 8 έως 16 άτομα άνθρακα στην 2- ή 3-θέση του μορφολινο δακτυλίου, και R2 είναι μία γραμμική ή διακλαδισμένη αλκυλική ομάδα η οποία περιέχει 2 έως 10 άτομα άνθρακα, υποκατεστημένη με μία υδροξυ ομάδα εκτός της άλφα-θέσης, ή ένα φαρμακευτικώς αποδεκτό άλας αυτής. Μία καλλυντική μέθοδος πρόληψης ή μείωσης της χρώσης του στόματος σε ένα ζώο, η οποία περιλαμβάνει το στάδιο της έκθεσης της στοματικής κοιλότητας σε μία μορφολινο ένωση του γενικού.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0604018.2A GB0604018D0 (en) | 2006-02-28 | 2006-02-28 | Method |
| PCT/GB2007/000680 WO2007099302A2 (en) | 2006-02-28 | 2007-02-27 | Methods of maintaining oral health in animals using morpholine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1119460T1 true CY1119460T1 (el) | 2018-03-07 |
Family
ID=36178958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20171101075T CY1119460T1 (el) | 2006-02-28 | 2017-10-12 | Μεθοδοι διατηρησης της στοματικης υγειας σε ζωα χρησιμοποιωντας παραγωγα μορφολινης |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US20110171143A1 (el) |
| EP (2) | EP3156057B1 (el) |
| CY (1) | CY1119460T1 (el) |
| DK (2) | DK3156057T3 (el) |
| ES (2) | ES2648218T3 (el) |
| GB (1) | GB0604018D0 (el) |
| HU (2) | HUE037203T2 (el) |
| LT (1) | LT1988903T (el) |
| PL (2) | PL1988903T3 (el) |
| PT (2) | PT1988903T (el) |
| SI (1) | SI1988903T1 (el) |
| WO (1) | WO2007099302A2 (el) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0604018D0 (en) * | 2006-02-28 | 2006-04-05 | Sinclair Pharmaceuticals Ltd | Method |
| EP2990034A4 (en) * | 2013-04-22 | 2017-04-26 | Obshchestvo S Ogranichennoy Otvetstvennostyu "Nanobiotekh" | Antiseptic veterinary formulation and methods for use thereof |
| IT201600130729A1 (it) | 2016-12-23 | 2018-06-23 | Lundbeck Pharmaceuticals Italy S P A | Processo per la produzione degli intermedi del delmopinolo |
| IT201600130538A1 (it) | 2016-12-23 | 2018-06-23 | Lundbeck Pharmaceuticals Italy S P A | Processo per la produzione del delmopinolo |
| IT201600130642A1 (it) | 2016-12-23 | 2018-06-23 | Lundbeck Pharmaceuticals Italy S P A | Processo per la produzione di 2(3 alchilmorfolino)-etan-1-olo |
| IT201700076821A1 (it) | 2017-08-24 | 2019-02-24 | Lundbeck Pharmaceuticals Italy S P A | Nuovo sale del delmopinolo |
| EP4096571A4 (en) | 2020-01-31 | 2024-03-06 | You First Services, Inc. | METHOD FOR PRODUCING DELMOPINOL AND SALTS THEREOF |
| WO2023183879A1 (en) * | 2022-03-23 | 2023-09-28 | You First Services, Inc. | Methods for irrigation using delmopinol and delmopinol salts |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE439011B (sv) * | 1980-03-21 | 1985-05-28 | Ferrosan Ab | Morfolinoforeningar, kompositioner innehallande dessa och anvendning derav |
| US4329333A (en) | 1980-11-24 | 1982-05-11 | Arthur Barr | Method for the oral treatment of dogs and other animals |
| US4894221A (en) * | 1981-03-19 | 1990-01-16 | Ab Ferrosan | Method of treating plaque using morpholine compounds |
| US4975270A (en) * | 1987-04-21 | 1990-12-04 | Nabisco Brands, Inc. | Elastomer encased active ingredients |
| EP0426826B1 (en) | 1989-05-24 | 1994-04-27 | Pharmacia AB | Substituted isoxazolidines and isoxazolines |
| US5015485A (en) * | 1989-05-30 | 1991-05-14 | Nabisco Brands, Inc. | Dog biscuits having a coating containing an inorganic pyrophosphate |
| US5082653A (en) * | 1990-10-31 | 1992-01-21 | Warner-Lambert Company | Anti-plaque compositions comprising a combination of morpholinoamino alcohol and antibiotic |
| US5085850A (en) * | 1990-11-09 | 1992-02-04 | Warner-Lambert Company | Anti-plaque compositions comprising a combination of morpholinoamino alcohol and metal salts |
| US5467741A (en) * | 1992-08-20 | 1995-11-21 | Booda Products, Inc. | Dog chew toy for canine dental care and methods for making chew toy |
| US5329881A (en) * | 1992-08-31 | 1994-07-19 | Booda Products, Inc. | Dog chew toy for canine dental care and methods for making chew toy |
| US6096328A (en) * | 1997-06-06 | 2000-08-01 | The Procter & Gamble Company | Delivery system for an oral care substance using a strip of material having low flexural stiffness |
| US5976549A (en) * | 1998-07-17 | 1999-11-02 | Lewandowski; Joan | Method to reduce bad breath in a pet by administering raw garlic |
| US7387774B2 (en) | 1999-11-12 | 2008-06-17 | The Procter & Gamble Co. | Method of enhancing fluoridation and mineralization of teeth |
| US20010043941A1 (en) * | 2000-03-23 | 2001-11-22 | Hiep Huatan | Oral formulations of medicaments |
| EP1136067A1 (en) * | 2000-03-23 | 2001-09-26 | Pfizer Limited | Oral formulations of medicaments |
| CA2415068C (en) | 2000-06-30 | 2009-03-10 | The Procter & Gamble Company | Oral compositions comprising antimicrobial agents |
| US20040115247A1 (en) * | 2001-01-12 | 2004-06-17 | Melman Steven A. | Multi-functional dental composition |
| CN1149936C (zh) | 2001-03-31 | 2004-05-19 | 朱招宠 | 一种猪皮狗咬胶的加工方法 |
| AU2002311922A1 (en) | 2001-05-15 | 2002-11-25 | The Procter And Gamble Company | Oral care compositions |
| US20040156884A1 (en) * | 2003-02-10 | 2004-08-12 | Brown Dale G. | Emulsion impregnated rawhide chews with antimicrobially active chlorhexidine |
| US9554984B2 (en) * | 2003-11-03 | 2017-01-31 | Jaleva Pharmaceuticals, Llc | Oral care compositions for topical application |
| AU2004308360B2 (en) * | 2003-12-22 | 2012-02-16 | Imrex, Inc. | Methods and compositions for oral hygiene |
| WO2005097053A1 (en) * | 2004-04-01 | 2005-10-20 | Smithkline Beecham Corporation | Dissolvable tooth whitening strip |
| US20060264497A1 (en) | 2005-03-28 | 2006-11-23 | Zeligs Michael A | Diindolylmethane-based compositions and methods of use thereof for promoting oral mucosal and bone health |
| BRPI0502145A (pt) | 2005-06-03 | 2007-01-23 | Mauricio Duarte Da Conceicao | enxaguatório para prevenção e tratamento da halitose |
| GB0523743D0 (en) * | 2005-11-22 | 2005-12-28 | Sinclair Pharmaceuticals Ltd | Method |
| GB0600431D0 (en) * | 2006-01-10 | 2006-02-15 | Sinclair Pharmaceuticals Ltd | Method |
| GB0604018D0 (en) * | 2006-02-28 | 2006-04-05 | Sinclair Pharmaceuticals Ltd | Method |
| US9089108B2 (en) * | 2007-06-29 | 2015-07-28 | Redbarn Pet Products, Inc. | Adhesion system for rawhide and meat chew for dogs |
| WO2018235038A1 (en) * | 2017-06-21 | 2018-12-27 | Beck Medical, Ltd. | METHODS OF USING NASAL INSERTS FOR TREATMENTS |
-
2006
- 2006-02-28 GB GBGB0604018.2A patent/GB0604018D0/en not_active Ceased
-
2007
- 2007-02-27 ES ES07712798.3T patent/ES2648218T3/es active Active
- 2007-02-27 HU HUE07712798A patent/HUE037203T2/hu unknown
- 2007-02-27 LT LTEP07712798.3T patent/LT1988903T/lt unknown
- 2007-02-27 PL PL07712798T patent/PL1988903T3/pl unknown
- 2007-02-27 PT PT77127983T patent/PT1988903T/pt unknown
- 2007-02-27 PT PT161866629T patent/PT3156057T/pt unknown
- 2007-02-27 EP EP16186662.9A patent/EP3156057B1/en active Active
- 2007-02-27 DK DK16186662.9T patent/DK3156057T3/da active
- 2007-02-27 SI SI200731984T patent/SI1988903T1/sl unknown
- 2007-02-27 EP EP07712798.3A patent/EP1988903B1/en active Active
- 2007-02-27 DK DK07712798.3T patent/DK1988903T3/en active
- 2007-02-27 ES ES16186662T patent/ES2961931T3/es active Active
- 2007-02-27 PL PL16186662.9T patent/PL3156057T3/pl unknown
- 2007-02-27 WO PCT/GB2007/000680 patent/WO2007099302A2/en active Application Filing
- 2007-02-27 HU HUE16186662A patent/HUE065668T2/hu unknown
- 2007-02-27 US US12/162,168 patent/US20110171143A1/en not_active Abandoned
-
2011
- 2011-07-12 US US13/180,962 patent/US20110268671A1/en not_active Abandoned
-
2015
- 2015-04-30 US US14/700,962 patent/US20150231048A1/en not_active Abandoned
-
2017
- 2017-10-12 CY CY20171101075T patent/CY1119460T1/el unknown
- 2017-11-01 US US15/801,109 patent/US10206928B2/en active Active
-
2019
- 2019-02-15 US US16/277,893 patent/US11660300B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007099302A3 (en) | 2008-06-19 |
| HUE037203T2 (hu) | 2018-08-28 |
| GB0604018D0 (en) | 2006-04-05 |
| LT1988903T (lt) | 2018-01-25 |
| DK3156057T3 (da) | 2024-01-29 |
| WO2007099302A2 (en) | 2007-09-07 |
| ES2961931T3 (es) | 2024-03-14 |
| US20180064719A1 (en) | 2018-03-08 |
| EP3156057A3 (en) | 2017-07-26 |
| EP1988903B1 (en) | 2017-08-23 |
| PL1988903T3 (pl) | 2018-02-28 |
| PT3156057T (pt) | 2023-12-07 |
| EP3156057A2 (en) | 2017-04-19 |
| US20110268671A1 (en) | 2011-11-03 |
| US20190175607A1 (en) | 2019-06-13 |
| US20150231048A1 (en) | 2015-08-20 |
| SI1988903T1 (sl) | 2017-12-29 |
| US20110171143A1 (en) | 2011-07-14 |
| EP1988903A2 (en) | 2008-11-12 |
| ES2648218T3 (es) | 2017-12-29 |
| US10206928B2 (en) | 2019-02-19 |
| WO2007099302A8 (en) | 2008-09-04 |
| EP3156057B1 (en) | 2023-10-04 |
| PT1988903T (pt) | 2017-11-30 |
| DK1988903T3 (en) | 2017-10-09 |
| HUE065668T2 (hu) | 2024-06-28 |
| PL3156057T3 (pl) | 2024-03-18 |
| US11660300B2 (en) | 2023-05-30 |
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