DE60126923T2 - Therapeutische zusammensetzungen bestehend aus antihypotensiva und antiangiogenika - Google Patents
Therapeutische zusammensetzungen bestehend aus antihypotensiva und antiangiogenika Download PDFInfo
- Publication number
- DE60126923T2 DE60126923T2 DE60126923T DE60126923T DE60126923T2 DE 60126923 T2 DE60126923 T2 DE 60126923T2 DE 60126923 T DE60126923 T DE 60126923T DE 60126923 T DE60126923 T DE 60126923T DE 60126923 T2 DE60126923 T2 DE 60126923T2
- Authority
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- Prior art keywords
- alkyl
- methoxy
- quinazoline
- yloxy
- oder
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- Expired - Lifetime
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| Application Number | Priority Date | Filing Date | Title |
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| GB0008269 | 2000-04-05 | ||
| GBGB0008269.3A GB0008269D0 (en) | 2000-04-05 | 2000-04-05 | Combination chemotherapy |
| PCT/GB2001/001522 WO2001074360A1 (en) | 2000-04-05 | 2001-04-02 | Therapeutic combinations of antihypertensive and antiangiogenic agents |
Publications (2)
| Publication Number | Publication Date |
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| DE60126923D1 DE60126923D1 (de) | 2007-04-12 |
| DE60126923T2 true DE60126923T2 (de) | 2007-10-31 |
Family
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| DE60126923T Expired - Lifetime DE60126923T2 (de) | 2000-04-05 | 2001-04-02 | Therapeutische zusammensetzungen bestehend aus antihypotensiva und antiangiogenika |
Country Status (29)
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| EP (3) | EP1658849A3 (https=) |
| JP (1) | JP2003528917A (https=) |
| KR (2) | KR100849149B1 (https=) |
| CN (1) | CN1431902A (https=) |
| AT (1) | ATE355065T1 (https=) |
| AU (2) | AU2001244386B2 (https=) |
| BR (1) | BR0109729A (https=) |
| CA (1) | CA2401854A1 (https=) |
| CY (1) | CY1107615T1 (https=) |
| CZ (1) | CZ299410B6 (https=) |
| DE (1) | DE60126923T2 (https=) |
| DK (1) | DK1272186T3 (https=) |
| EE (1) | EE200200578A (https=) |
| ES (1) | ES2280349T3 (https=) |
| GB (1) | GB0008269D0 (https=) |
| HU (1) | HUP0300426A2 (https=) |
| IL (1) | IL151503A0 (https=) |
| IS (2) | IS2455B (https=) |
| MX (1) | MXPA02009743A (https=) |
| NO (2) | NO323467B1 (https=) |
| NZ (2) | NZ520938A (https=) |
| PL (1) | PL357605A1 (https=) |
| PT (1) | PT1272186E (https=) |
| RU (1) | RU2002129353A (https=) |
| SI (1) | SI1272186T1 (https=) |
| SK (1) | SK14302002A3 (https=) |
| WO (1) | WO2001074360A1 (https=) |
| ZA (1) | ZA200206959B (https=) |
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| US7381413B1 (en) * | 1998-04-17 | 2008-06-03 | University Of Vermont And State Agricultural College | Methods and products related to metabolic interactions in disease |
| KR100881105B1 (ko) * | 1999-11-05 | 2009-02-02 | 아스트라제네카 아베 | Ｖｅｇｆ 억제제로서의 퀴나졸린 유도체 |
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| ES2267748T3 (es) | 2000-04-07 | 2007-03-16 | Astrazeneca Ab | Compuestos de quinazolina. |
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| SI1474420T1 (sl) * | 2002-02-01 | 2012-06-29 | Astrazeneca Ab | Spojine kinazolina |
| BR0309226A (pt) * | 2002-04-16 | 2005-02-09 | Astrazeneca Ab | Métodos para a produção de um efeito de danificação vascular em um animal de sangue quente, e para o tratamento de um câncer envolvendo um tumor sólido em um animal de sangue quente, composição farmacêutica, kit, e, usos de zd6126 ou de um seu sal farmaceuticamente aceitável, e de zd1839 ou de um seu sal farmaceuticamente aceitável |
| US7358236B1 (en) * | 2002-06-21 | 2008-04-15 | Oxigene, Inc. | Control of acute hypertension and cardiotoxicity in patients treated with vascular targeting agents |
| US7576074B2 (en) | 2002-07-15 | 2009-08-18 | Rice Kenneth D | Receptor-type kinase modulators and methods of use |
| US7435419B2 (en) * | 2002-07-19 | 2008-10-14 | Beth Israel Deaconess Medical Center | Methods of diagnosing and treating pre-eclampsia or eclampsia |
| KR101215701B1 (ko) * | 2002-07-19 | 2012-12-26 | 베스 이스라엘 데코니스 메디칼 센터 | 자간전증 또는 자간의 진단 및 치료 방법 |
| US7335362B2 (en) * | 2002-07-19 | 2008-02-26 | Beth Israel Deaconess Medical Center | Methods of treating pre-eclampsia or eclampsia |
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| GB0223380D0 (en) * | 2002-10-09 | 2002-11-13 | Astrazeneca Ab | Combination therapy |
| AU2003278383B2 (en) | 2002-11-04 | 2007-06-14 | Astrazeneca Ab | Quinazoline derivatives as Src tyrosine kinase inhibitors |
| KR20050100683A (ko) * | 2003-02-13 | 2005-10-19 | 아스트라제네카 아베 | 5-ｆｕ 또는/및 ｃｐｔ-11과 ｚｄ6474의 병용 요법 |
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| GB0310401D0 (en) * | 2003-05-07 | 2003-06-11 | Astrazeneca Ab | Therapeutic agent |
| JP2006527753A (ja) * | 2003-06-18 | 2006-12-07 | アンギオジェン・ファーマシューティカルズ・リミテッド | 結腸直腸癌などの治療のための、血管損傷効果を有する、５−ｆｕ、ｃｐｔ−１１または５−ｆｕおよびｃｐｔ−１１と組み合わせたｚｄ６１２６を含んでなる組成物 |
| EP1648465B1 (en) * | 2003-07-10 | 2010-08-25 | AstraZeneca AB | Use of the quinazoline derivative zd6474 combined with platinum compounds and optionally ionising radiation in the treatment of diseases associated with angiogenesis and/or increased vascular permeability |
| GB0316123D0 (en) * | 2003-07-10 | 2003-08-13 | Astrazeneca Ab | Combination therapy |
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| GB0318422D0 (en) | 2003-08-06 | 2003-09-10 | Astrazeneca Ab | Chemical compounds |
| ES2314444T3 (es) | 2003-08-29 | 2009-03-16 | Pfizer Inc. | Tienopiridina-fenilacetaminasy sus derivados utiles como nuevos agentes antiangiogenicos. |
| AU2004309166B2 (en) * | 2003-12-23 | 2008-02-21 | Pfizer Inc. | Novel quinoline derivatives |
| GB0330002D0 (en) | 2003-12-24 | 2004-01-28 | Astrazeneca Ab | Quinazoline derivatives |
| GB0406445D0 (en) * | 2004-03-23 | 2004-04-28 | Astrazeneca Ab | Combination therapy |
| MXPA06010755A (es) * | 2004-03-23 | 2006-12-15 | Astrazeneca Ab | Terapia de combinacion. |
| US20070142433A1 (en) * | 2004-04-06 | 2007-06-21 | Helmut Augustin | Angiogenesis-affecting compounds and methods of use thereof |
| US20070142308A1 (en) * | 2005-04-06 | 2007-06-21 | Helmut Augustin | Angiogenesis-affecting compounds and methods for use thereof |
| EP1737452A1 (en) * | 2004-04-06 | 2007-01-03 | Angiogenetics Sweden AB | Angiogenesis-affecting compounds and methods of use thereof |
| US8273383B2 (en) * | 2004-05-04 | 2012-09-25 | Children's Medical Center Corporation | Methods and compositions for treatment of preeclampsia |
| DE602005025755D1 (de) | 2004-06-04 | 2011-02-17 | Teva Pharma | Irbesartan enthaltende pharmazeutische zusammensetzung |
| EP2347765B1 (en) | 2004-09-24 | 2014-01-22 | Beth Israel Deaconess Medical Center | Methods of diagnosing and treating complications of pregnancy |
| US7740849B2 (en) * | 2004-09-24 | 2010-06-22 | Beth Israel Deaconess Medical Center | Use of compounds that bind soluble endoglin and SFLT-1 for the treatment of pregnancy related hypertensive disorders |
| KR20070072543A (ko) * | 2004-09-27 | 2007-07-04 | 아스트라제네카 아베 | Ｚｄ6474 및 이마티닙을 포함하는 병합법 |
| GB0424339D0 (en) * | 2004-11-03 | 2004-12-08 | Astrazeneca Ab | Combination therapy |
| JP4954085B2 (ja) | 2004-12-06 | 2012-06-13 | メディシノバ， インコーポレイテッド | 神経障害性疼痛及びその関連する症状を治療するためのイブジラスト |
| DE602005023216D1 (de) * | 2004-12-15 | 2010-10-07 | Beth Israel Hospital | Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationen |
| EP1853298A2 (en) | 2005-02-11 | 2007-11-14 | Regeneron Pharmaceuticals, Inc. | Therapeutic combination of a vegf antagonist (vegf trap) and an anti-hypertensive agent |
| MX2007010965A (es) * | 2005-03-09 | 2007-09-19 | Merck & Co Inc | Antagonistas de canales de calcio de tipo t de quinazolinona. |
| KR20080031029A (ko) * | 2005-07-06 | 2008-04-07 | 아스트라제네카 아베 | Ａｚｄ2171 및 젬시타빈에 의한 암의 병용 요법 |
| AU2006277742B2 (en) | 2005-08-08 | 2010-08-26 | Pfizer Inc. | Salts and polymorphs of a VEGF-R inhibitor |
| CA2615636A1 (en) * | 2005-08-12 | 2007-02-22 | Regeneron Pharmaceuticals, Inc. | Treatment of diseases by subcutaneous administration of a vegf antagonist |
| HRP20110365T1 (hr) * | 2005-12-22 | 2011-06-30 | Astrazeneca Ab | Kombinacija azd2171 i pemetrekseda |
| PL1971338T3 (pl) * | 2005-12-22 | 2011-07-29 | Astrazeneca Ab | Połączenie ZD6474 i premetreksedu |
| US20090286271A1 (en) * | 2006-05-31 | 2009-11-19 | Karumanchi Ananth S | Methods of Diagnosing and Treating Complications of Pregnancy |
| WO2008037996A1 (en) * | 2006-09-29 | 2008-04-03 | Astrazeneca Ab | Combination of zd6474 and bevacizumab for cancer therapy |
| US20080153819A1 (en) * | 2006-12-21 | 2008-06-26 | Bingaman David P | Methods for treating macular edema and pathologic ocular angiogenesis using a neuroprotective agent and a receptor tyrosine kinase inhibitor |
| US20080181876A1 (en) * | 2007-01-30 | 2008-07-31 | Johnson Kirk W | Methods for treating acute and subchronic pain |
| US20080190689A1 (en) * | 2007-02-12 | 2008-08-14 | Ballard Ebbin C | Inserts for engine exhaust systems |
| CA2684938A1 (en) * | 2007-05-02 | 2008-11-13 | Tau Therapeutics Llc | Dihydropyridine derivative for treating cancer or a pre-cancerous condition and other conditions |
| WO2008137012A1 (en) * | 2007-05-03 | 2008-11-13 | Avigen, Inc. | Use of a glial attenuator to prevent amplified pain responses caused by glial priming |
| AU2008275674A1 (en) * | 2007-07-10 | 2009-01-15 | Merck & Co., Inc. | Quinazolinone T-type calcium channel antagonists |
| WO2010008554A2 (en) | 2008-07-14 | 2010-01-21 | The Regents Of The University Of Colorado | Methods and products for treating proliferative diseases |
| EP2542155B1 (en) | 2010-03-01 | 2015-11-04 | TAU Therapeutics LLC | Method for imaging a disease |
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