DE60121695D1 - Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen - Google Patents

Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen

Info

Publication number
DE60121695D1
DE60121695D1 DE60121695T DE60121695T DE60121695D1 DE 60121695 D1 DE60121695 D1 DE 60121695D1 DE 60121695 T DE60121695 T DE 60121695T DE 60121695 T DE60121695 T DE 60121695T DE 60121695 D1 DE60121695 D1 DE 60121695D1
Authority
DE
Germany
Prior art keywords
dermatitis
treatment
chymaseinhibitors
drugs
effective agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60121695T
Other languages
English (en)
Other versions
DE60121695T2 (de
Inventor
Harukazu Fukami
Yoshiaki Tomimori
Yoshiaki Fukuda
Naohiro Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Sankyo Co Ltd
Original Assignee
Daiichi Asubio Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Asubio Pharma Co Ltd filed Critical Daiichi Asubio Pharma Co Ltd
Publication of DE60121695D1 publication Critical patent/DE60121695D1/de
Application granted granted Critical
Publication of DE60121695T2 publication Critical patent/DE60121695T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
DE60121695T 2000-02-22 2001-02-22 Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen Expired - Lifetime DE60121695T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000050504 2000-02-22
JP2000050504 2000-02-22
PCT/JP2001/001323 WO2001062294A1 (fr) 2000-02-22 2001-02-22 Medicaments preventifs ou therapeutiques contenant des inhibiteurs de chymase en tant que principe actif, pour traiter des dermatites

Publications (2)

Publication Number Publication Date
DE60121695D1 true DE60121695D1 (de) 2006-09-07
DE60121695T2 DE60121695T2 (de) 2007-08-30

Family

ID=18572276

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60121695T Expired - Lifetime DE60121695T2 (de) 2000-02-22 2001-02-22 Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen

Country Status (11)

Country Link
US (2) US7618977B2 (de)
EP (1) EP1192950B1 (de)
KR (1) KR20010109356A (de)
CN (1) CN1245979C (de)
AT (1) ATE333897T1 (de)
AU (1) AU3413601A (de)
CA (1) CA2368382A1 (de)
DE (1) DE60121695T2 (de)
ES (1) ES2269347T3 (de)
HU (1) HUP0201282A3 (de)
WO (1) WO2001062294A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3413401A (en) 2000-02-22 2001-09-03 Daiichi Asubio Pharma Co., Ltd. Preventive or therapeutic drugs for fibrosis containing chymase inhibitors as the active ingredient
DE60126199T2 (de) 2000-02-22 2008-02-28 Asubio Pharma Co., Ltd. Therapeutische behandlung von eosinophilie durch verwendung von chymase-inhibitoren als aktive bestandteile
US7361767B2 (en) * 2003-11-14 2008-04-22 3M Innovative Properties Company N-sulfonyldicarboximide containing tethering compounds
AU2005310490B2 (en) 2004-12-02 2012-01-19 Daiichi Sankyo Company, Limited 7-membered ring compound, process for producing the same, and medicinal use thereof
US8071307B2 (en) 2005-04-04 2011-12-06 Asubio Pharma Co., Ltd. Method of detecting relative risk for the onset of atopic dermatitis by gene single nucleotide polymorphism analysis
CN101495463B (zh) 2006-05-31 2012-08-15 第一三共株式会社 7-元环化合物、其制备方法和药物用途
WO2015067651A1 (de) * 2013-11-08 2015-05-14 Bayer Pharma Aktiengesellschaft Substituierte uracile als chymase inhibitoren
AU2017416068A1 (en) 2017-05-24 2019-10-31 The Provost, Fellows, Foundation Scholars, And Other Members Of Board, Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Novel compounds and uses
US11639503B2 (en) * 2017-11-30 2023-05-02 Ribomic Inc. Anti-chymase aptamer and use for same

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684654A (en) * 1985-08-14 1987-08-04 American Cyanamid Company 3-heteroalkyl-2,4-quinzaolinediones
IL79249A (en) * 1986-06-26 1992-02-16 Makhteshim Chem Works Ltd Herbicidal compositions containing haloalkylthioquinazoline di(thi)ones and some new such compounds
JP2832923B2 (ja) * 1990-07-13 1998-12-09 吉富製薬株式会社 スチリル化合物およびその医薬用途
IE913473A1 (en) * 1990-10-15 1992-04-22 Fujisawa Pharmaceutical Co Quinazoline derivatives and their preparation
US5199279A (en) 1991-08-13 1993-04-06 Reynolds Martin M Drum contact freezer system and method
JPH05294930A (ja) * 1992-04-21 1993-11-09 Yoshitomi Pharmaceut Ind Ltd スチリル化合物
EP0644892A1 (de) 1992-06-12 1995-03-29 Pfizer Inc. Inhibitoren für Angiotensin I-Chymasen inklusive der menschlichen Herzchymase
CZ291264B6 (cs) 1993-05-12 2003-01-15 E.I. Du Pont De Nemours And Company Kondenzované bicyklické pyrimidinony, fungicidní prostředek a způsob potlačování padlí travního
ES2155134T3 (es) * 1994-07-29 2001-05-01 Suntory Ltd Derivados de imidazolidina y su utilizacion.
KR100400639B1 (ko) 1995-04-27 2003-12-31 미쯔비시 웰 파마 가부시키가이샤 복소환식아미드화합물및그의의약용도
US5596111A (en) 1995-06-05 1997-01-21 North Dakota State University Method for preparation of carboxylic acids
WO1997011941A1 (en) 1995-09-28 1997-04-03 Suntory Limited Quinazoline derivatives and use thereof
MXPA99002203A (es) 1996-09-06 2003-09-15 Nippon Kayaku Kk Nuevos derivados de acetamida e inhibidores de proteasa.
JPH1087493A (ja) * 1996-09-18 1998-04-07 Shionogi & Co Ltd セフェム系化合物を含有するキマーゼ阻害剤
JPH10101666A (ja) * 1996-10-02 1998-04-21 Shionogi & Co Ltd 新規ベンゾオキサシクロトリデシン化合物およびそれを含有する医薬組成物
EP0940400A4 (de) 1996-10-25 2002-10-02 Mitsubishi Pharma Corp Heterocyklische amidverbindungen und ihre medizinische anwendung
JPH10245384A (ja) * 1997-03-05 1998-09-14 Teijin Ltd 新規トリアジンスルホン誘導体
WO1999041277A1 (fr) 1998-02-17 1999-08-19 Nippon Kayaku Kabushiki Kaisha Nouveau derive d'acetamide et son utilisation
IL140862A (en) 1998-07-15 2005-05-17 Teijin Ltd Thiobenzimidazole derivatives and pharmaceutical compositions containing the same
KR20010089168A (ko) 1998-08-21 2001-09-29 도리이 신이치로 퀴나졸린 유도체 및 이의 약제학적 용도
JP2000247908A (ja) * 1999-03-01 2000-09-12 Welfide Corp かゆみ抑制剤
EP1142586B1 (de) 1999-11-01 2007-04-25 Daiichi Asubio Pharma Co., Ltd. Verwendung von chymase hemmern gegen vaskuläre lipidablagerung
DE60126199T2 (de) 2000-02-22 2008-02-28 Asubio Pharma Co., Ltd. Therapeutische behandlung von eosinophilie durch verwendung von chymase-inhibitoren als aktive bestandteile
AU3413401A (en) 2000-02-22 2001-09-03 Daiichi Asubio Pharma Co., Ltd. Preventive or therapeutic drugs for fibrosis containing chymase inhibitors as the active ingredient

Also Published As

Publication number Publication date
KR20010109356A (ko) 2001-12-08
HUP0201282A3 (en) 2003-02-28
US20020183339A1 (en) 2002-12-05
US20100029695A1 (en) 2010-02-04
ATE333897T1 (de) 2006-08-15
US7618977B2 (en) 2009-11-17
CN1245979C (zh) 2006-03-22
HUP0201282A2 (hu) 2002-12-28
AU3413601A (en) 2001-09-03
EP1192950B1 (de) 2006-07-26
CA2368382A1 (en) 2001-08-30
CN1366460A (zh) 2002-08-28
EP1192950A1 (de) 2002-04-03
WO2001062294A1 (fr) 2001-08-30
DE60121695T2 (de) 2007-08-30
EP1192950A4 (de) 2003-01-22
ES2269347T3 (es) 2007-04-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ASUBIO PHARMA CO., LTD., TOKYO, JP

8327 Change in the person/name/address of the patent owner

Owner name: DAIICHI SANKYO COMPANY, LIMITED, TOKIO, JP