DE60109616D1 - Immunoassay und immunoassayvorrichtung - Google Patents

Immunoassay und immunoassayvorrichtung

Info

Publication number
DE60109616D1
DE60109616D1 DE60109616T DE60109616T DE60109616D1 DE 60109616 D1 DE60109616 D1 DE 60109616D1 DE 60109616 T DE60109616 T DE 60109616T DE 60109616 T DE60109616 T DE 60109616T DE 60109616 D1 DE60109616 D1 DE 60109616D1
Authority
DE
Germany
Prior art keywords
immunoassay
immunoassay device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60109616T
Other languages
English (en)
Other versions
DE60109616T2 (de
Inventor
Kazuhiro Nakashima
Tsuneyoshi Torii
Hiroshi Tsuchiya
Shinya Uchida
Aya Konishi
Kunio Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sysmex Corp
Original Assignee
Sysmex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sysmex Corp filed Critical Sysmex Corp
Application granted granted Critical
Publication of DE60109616D1 publication Critical patent/DE60109616D1/de
Publication of DE60109616T2 publication Critical patent/DE60109616T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N2015/0092—Monitoring flocculation or agglomeration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486—Counting the particles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/106664—Blood serum or blood plasma standard or control
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125—Digestion or removing interfering materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DE60109616T 2000-06-12 2001-06-11 Immunoassay und immunoassayvorrichtung Expired - Lifetime DE60109616T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP2000175914 2000-06-12
JP2000175914 2000-06-12
JP2000179058 2000-06-14
JP2000179058 2000-06-14
JP2000236199 2000-08-03
JP2000236199 2000-08-03
PCT/JP2001/004917 WO2001096868A2 (en) 2000-06-12 2001-06-11 Immunoassay and immunoassay apparatus

Publications (2)

Publication Number Publication Date
DE60109616D1 true DE60109616D1 (de) 2005-04-28
DE60109616T2 DE60109616T2 (de) 2006-05-11

Family

ID=27343704

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60109616T Expired - Lifetime DE60109616T2 (de) 2000-06-12 2001-06-11 Immunoassay und immunoassayvorrichtung

Country Status (9)

Country Link
US (1) US7390677B2 (de)
EP (1) EP1297336B1 (de)
JP (1) JP4796265B2 (de)
KR (1) KR20020021808A (de)
CN (1) CN1317394C (de)
AU (1) AU6424201A (de)
CA (1) CA2373139A1 (de)
DE (1) DE60109616T2 (de)
WO (1) WO2001096868A2 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1365240B1 (de) * 2002-05-22 2006-09-13 Sysmex Corporation Immunologische Verfahren, Vorrichtungen und Reagenzien
JP4299597B2 (ja) * 2002-07-29 2009-07-22 シスメックス株式会社 血液分析装置及び方法
JP4490069B2 (ja) 2003-09-29 2010-06-23 シスメックス株式会社 臨床検査システム
JP4567326B2 (ja) * 2003-12-24 2010-10-20 三菱化学メディエンス株式会社 全血を用いる測定法
JP4435581B2 (ja) * 2004-01-07 2010-03-17 シスメックス株式会社 免疫測定装置および方法
US9040305B2 (en) 2004-09-28 2015-05-26 Singulex, Inc. Method of analysis for determining a specific protein in blood samples using fluorescence spectrometry
US8685711B2 (en) 2004-09-28 2014-04-01 Singulex, Inc. Methods and compositions for highly sensitive detection of molecules
GB2426391B (en) 2005-05-17 2009-12-09 Milwaukee Electric Tool Corp Power tool, battery, charger and method of operating the same
GB2428471A (en) * 2005-07-18 2007-01-31 Mathshop Ltd Flow cytometry
US7749722B2 (en) 2005-12-15 2010-07-06 Mitsubishi Kagaku Istron, Inc. Measuring method using whole blood
EP2081024A4 (de) * 2006-09-25 2013-10-16 Kowa Kabushiki Kaisha Vorrichtung zur gelatinebestimmung und probenzelle
JP4969292B2 (ja) * 2007-03-30 2012-07-04 シスメックス株式会社 試料分析装置
CN103543094B (zh) 2007-12-19 2017-06-09 神谷来克斯公司 单分子检测用扫描分析器和使用方法
EP2909604B1 (de) 2008-10-23 2019-06-26 M-I L.L.C. Verfahren und vorrichtung zur messung der partikelgrössenverteilung in einer bohrflüssigkeit
US9007580B2 (en) 2011-04-11 2015-04-14 Schlumberger Norge As Method and apparatus for measuring particle size distribution in drilling fluid
JP5304456B2 (ja) * 2009-06-10 2013-10-02 ソニー株式会社 微小粒子測定装置
JP5629447B2 (ja) * 2009-10-07 2014-11-19 株式会社セイシン企業 粒子性状の測定方法及び装置並びに測定試料の調製装置
JP5806884B2 (ja) * 2010-09-24 2015-11-10 株式会社堀場製作所 全血免疫測定装置及び全血免疫測定方法
CN102879319B (zh) * 2012-10-17 2014-06-18 许旭欣 调整反应细胞浓度的流式细胞测速方法
JP2014122851A (ja) * 2012-12-21 2014-07-03 Sysmex Corp 免疫測定方法および免疫測定装置
FR3003353B1 (fr) * 2013-03-14 2015-03-06 Horiba Abx Sas Nouvelle methode de dosage en flux d'un objet d'interet
FR3034524B1 (fr) * 2015-03-31 2017-04-28 Commissariat Energie Atomique Procede de determination du niveau d'agglutination de particules dans un echantillon
WO2016171198A1 (ja) * 2015-04-21 2016-10-27 国立大学法人東京大学 微粒子検出システム及び微粒子検出プログラム
JP6541623B2 (ja) * 2016-06-20 2019-07-10 東京エレクトロン株式会社 プラズマ処理装置、及び波形補正方法
CN110609139B (zh) * 2018-06-14 2023-06-30 深圳市理邦精密仪器股份有限公司 抗原浓度过量检测方法、装置及存储介质
CN109490175A (zh) * 2018-10-17 2019-03-19 南宁优康电子科技有限公司 细胞计数分类装置
CN113227757B (zh) * 2018-12-28 2024-04-16 深圳迈瑞生物医疗电子股份有限公司 一种血液细胞参数修正方法、血液样本检测仪和存储介质
CN109738348A (zh) * 2019-01-28 2019-05-10 大连医科大学 基于颗粒计数的免疫凝集反应强度定量分析方法
CN109932517B (zh) * 2019-04-04 2022-03-11 烟台海深威医学技术有限公司 一种血液凝集判断方法及装置
JP7469309B2 (ja) 2019-07-24 2024-04-16 大塚製薬株式会社 測定方法および測定装置
CN110749535B (zh) * 2019-10-15 2022-02-01 迈克医疗电子有限公司 流式细胞检测系统及方法

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US4279506A (en) * 1977-11-03 1981-07-21 R. J. Harvey Instruments Corp. Photometric apparatus and methods for counting the particulate components of blood
JPH07117541B2 (ja) * 1988-10-15 1995-12-18 オリンパス光学工業株式会社 磁性粒子を用いた免疫学的測定方法
JP2912413B2 (ja) * 1990-03-28 1999-06-28 東亜医用電子株式会社 粒度分布作成方法
JPH0552848A (ja) * 1991-08-23 1993-03-02 Hitachi Ltd 免疫測定法および装置
JPH05215750A (ja) * 1992-02-06 1993-08-24 Idemitsu Petrochem Co Ltd 免疫学的分析方法
US5763199A (en) * 1994-09-29 1998-06-09 Mount Sinai School Of Medicine Of The City University Of New York Platelet blockade assay
JP3249919B2 (ja) * 1996-07-30 2002-01-28 株式会社堀場製作所 免疫測定方法
US5858648A (en) * 1996-11-04 1999-01-12 Sienna Biotech, Inc. Assays using reference microparticles
JP3908856B2 (ja) * 1998-04-15 2007-04-25 株式会社堀場製作所 ラテックス免疫比濁法による免疫測定用フロー測光セル
CN1243251A (zh) * 1998-07-28 2000-02-02 华美生物工程公司郑州分公司 全血免疫检测试剂中红细胞和血清的分离方法
JP2000131320A (ja) * 1998-08-19 2000-05-12 Shino Test:Kk 特異的結合物質固定粒子を用いる被検物質の測定方法
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Also Published As

Publication number Publication date
CA2373139A1 (en) 2001-12-20
AU6424201A (en) 2001-12-24
EP1297336A2 (de) 2003-04-02
WO2001096868A2 (en) 2001-12-20
JP4796265B2 (ja) 2011-10-19
DE60109616T2 (de) 2006-05-11
JP2004503779A (ja) 2004-02-05
US20030082662A1 (en) 2003-05-01
CN1317394C (zh) 2007-05-23
CN1439100A (zh) 2003-08-27
EP1297336B1 (de) 2005-03-23
KR20020021808A (ko) 2002-03-22
WO2001096868A3 (en) 2003-01-30
US7390677B2 (en) 2008-06-24

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