DE60108651T2 - Wärmegelierende, biologisch abbaubare, wäßrige Polymerlösung - Google Patents
Wärmegelierende, biologisch abbaubare, wäßrige Polymerlösung Download PDFInfo
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- DE60108651T2 DE60108651T2 DE60108651T DE60108651T DE60108651T2 DE 60108651 T2 DE60108651 T2 DE 60108651T2 DE 60108651 T DE60108651 T DE 60108651T DE 60108651 T DE60108651 T DE 60108651T DE 60108651 T2 DE60108651 T2 DE 60108651T2
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- biodegradable
- polymer
- active agent
- biologically active
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- XDJYMJULXQKGMM-UHFFFAOYSA-N polymyxin E1 Natural products CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(C(C)O)NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCN)NC1=O XDJYMJULXQKGMM-UHFFFAOYSA-N 0.000 description 1
- KNIWPHSUTGNZST-UHFFFAOYSA-N polymyxin E2 Natural products CC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(C(C)O)NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCN)NC1=O KNIWPHSUTGNZST-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/66—Polyesters containing oxygen in the form of ether groups
- C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Polymers & Plastics (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Polyesters Or Polycarbonates (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Biological Depolymerization Polymers (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Polymerisation Methods In General (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23692600P | 2000-09-28 | 2000-09-28 | |
| US236926P | 2000-09-28 | ||
| US09/833,460 US6841617B2 (en) | 2000-09-28 | 2001-04-11 | Thermogelling biodegradable aqueous polymer solution |
| US833460 | 2001-04-11 | ||
| PCT/US2001/030322 WO2002026215A2 (en) | 2000-09-28 | 2001-09-27 | Thermogelling biodegradable aqueous polymer solution |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60108651D1 DE60108651D1 (de) | 2005-03-03 |
| DE60108651T2 true DE60108651T2 (de) | 2006-03-30 |
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| Application Number | Title | Priority Date | Filing Date |
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| DE60108651T Expired - Lifetime DE60108651T2 (de) | 2000-09-28 | 2001-09-27 | Wärmegelierende, biologisch abbaubare, wäßrige Polymerlösung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6841617B2 (enExample) |
| EP (1) | EP1320359B1 (enExample) |
| JP (1) | JP5031974B2 (enExample) |
| AT (1) | ATE287705T1 (enExample) |
| AU (2) | AU9482801A (enExample) |
| CA (1) | CA2423488C (enExample) |
| DE (1) | DE60108651T2 (enExample) |
| WO (1) | WO2002026215A2 (enExample) |
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| US7087244B2 (en) * | 2000-09-28 | 2006-08-08 | Battelle Memorial Institute | Thermogelling oligopeptide polymers |
| US6841617B2 (en) | 2000-09-28 | 2005-01-11 | Battelle Memorial Institute | Thermogelling biodegradable aqueous polymer solution |
| US20040228794A1 (en) * | 1998-04-10 | 2004-11-18 | Battelle Memorial Institute | Therapeutic agent carrier compositions |
| US20060177416A1 (en) | 2003-10-14 | 2006-08-10 | Medivas, Llc | Polymer particle delivery compositions and methods of use |
| US20040185101A1 (en) * | 2001-03-27 | 2004-09-23 | Macromed, Incorporated. | Biodegradable triblock copolymers as solubilizing agents for drugs and method of use thereof |
| US7649023B2 (en) | 2002-06-11 | 2010-01-19 | Novartis Ag | Biodegradable block copolymeric compositions for drug delivery |
| AR039729A1 (es) * | 2002-06-25 | 2005-03-09 | Alza Corp | Formulaciones de deposito de corta duracion |
| US8986737B2 (en) | 2002-09-05 | 2015-03-24 | Wm. Marsh Rice University | Antibiotic microspheres for treatment and prevention of osteomyelitis and enhancement of bone regrowth |
| EP1549246B1 (en) * | 2002-09-05 | 2012-05-02 | Catherine G. Ambrose | Antibiotic micropheres for treatment of infections and osteomyelitis |
| TW200410717A (en) * | 2002-12-31 | 2004-07-01 | Ind Tech Res Inst | Delivery system for control release of temperature sensitive bioactive material |
| GB0307011D0 (en) * | 2003-03-27 | 2003-04-30 | Regentec Ltd | Porous matrix |
| AU2004201264B2 (en) * | 2003-03-28 | 2009-12-24 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Adhesive Antineoplastic Compositions |
| US7051654B2 (en) | 2003-05-30 | 2006-05-30 | Clemson University | Ink-jet printing of viable cells |
| WO2005000268A2 (en) | 2003-06-26 | 2005-01-06 | Control Delivery Systems, Inc. | Bioerodible sustained release drug delivery systems |
| EP1635875B8 (en) * | 2003-06-26 | 2008-12-24 | pSivida Inc | In-situ gelling drug delivery system |
| GB2408510B (en) * | 2003-11-28 | 2008-05-14 | Ind Tech Res Inst | Thermosensitive biodegradable copolymer |
| US20060034889A1 (en) | 2004-08-16 | 2006-02-16 | Macromed, Inc. | Biodegradable diblock copolymers having reverse thermal gelation properties and methods of use thereof |
| US8128952B2 (en) * | 2005-01-12 | 2012-03-06 | Clemson University Research Foundation | Ligand-mediated controlled drug delivery |
| US8663686B2 (en) * | 2005-05-09 | 2014-03-04 | University Of Washington | Biodegradable chitosan-PEG compositions and methods of use |
| WO2007038246A2 (en) | 2005-09-22 | 2007-04-05 | Medivas, Llc | Solid polymer delivery compositions and methods for use thereof |
| WO2007035938A2 (en) | 2005-09-22 | 2007-03-29 | Medivas, Llc | BIS-(α-AMINO)-DIOL-DIESTER-CONTAINING POLY(ESTER AMIDE) AND POLY(ESTER URETHANE) COMPOSITIONS AND METHODS OF USE |
| US20070237803A1 (en) * | 2006-04-11 | 2007-10-11 | Medtronic Vascular, Inc. | Biodegradable Biocompatible Amphiphilic Copolymers for Coating and Manufacturing Medical Devices |
| US8974542B2 (en) | 2006-06-27 | 2015-03-10 | University of Pittsburgh—of the Commonwealth System of Higher Education | Biodegradable elastomeric patch for treating cardiac or cardiovascular conditions |
| WO2008045904A2 (en) * | 2006-10-10 | 2008-04-17 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Thermoresponsive, biodegradable, elastomeric material |
| US20080140106A1 (en) * | 2006-12-12 | 2008-06-12 | Kimberly-Clark Worldwide, Inc. | Enhanced cuff sealing for endotracheal tubes |
| JP5264103B2 (ja) * | 2007-05-09 | 2013-08-14 | 学校法人 関西大学 | 温度応答性を有する生分解性グラフト共重合体 |
| US20090004243A1 (en) | 2007-06-29 | 2009-01-01 | Pacetti Stephen D | Biodegradable triblock copolymers for implantable devices |
| JP5171146B2 (ja) * | 2007-07-27 | 2013-03-27 | 学校法人 関西大学 | 温度応答性を有する生分解性ポリマー及びその製造方法 |
| US8642062B2 (en) | 2007-10-31 | 2014-02-04 | Abbott Cardiovascular Systems Inc. | Implantable device having a slow dissolving polymer |
| US20110027379A1 (en) * | 2007-12-06 | 2011-02-03 | Cornell University | Oligo-Ethylene Glycol-Based Polymer Compositions and Methods of Use |
| US20090286907A1 (en) * | 2008-01-23 | 2009-11-19 | Beltz Mark W | Fumaric Acid/Diol Polyesters and Their Manufacture and Use |
| TWI388591B (zh) * | 2008-03-28 | 2013-03-11 | Ind Tech Res Inst | 溫度敏感性材料 |
| US8916188B2 (en) * | 2008-04-18 | 2014-12-23 | Abbott Cardiovascular Systems Inc. | Block copolymer comprising at least one polyester block and a poly (ethylene glycol) block |
| JP5435534B2 (ja) * | 2008-08-27 | 2014-03-05 | 多木化学株式会社 | 生体材料 |
| US8821364B2 (en) * | 2008-09-02 | 2014-09-02 | Battelle Memorial Institute | Brachytherapy seed with fast dissolving matrix for optimal delivery of radionuclides to cancer tissue |
| TWI374903B (en) * | 2008-12-31 | 2012-10-21 | Ind Tech Res Inst | Biodegradable copolymer hydrogel materials |
| US8827884B2 (en) | 2009-08-06 | 2014-09-09 | Koninklijke Philips N.V. | Oncology therapies employing radioactive seeds |
| DK2478066T3 (en) * | 2009-09-18 | 2017-06-19 | Protherics Medicines Dev Ltd | BAB TRIBLOCK POLYMERS WITH IMPROVED DELIVERY CHARACTERISTICS |
| JP5653441B2 (ja) * | 2009-09-18 | 2015-01-14 | プロセリクス メディスンズ ディベロプメント リミテッド | 再構成可能な逆熱ゲル化性ポリマー |
| US8796234B2 (en) | 2009-11-24 | 2014-08-05 | Agency For Science, Technology And Research | Crosslinking branched molecule through thiol-disulfide exchange to form hydrogel |
| US9421307B2 (en) | 2010-08-17 | 2016-08-23 | University of Pittsburgh—of the Commonwealth System of Higher Education | Biohybrid composite scaffold |
| CA2857944C (en) | 2011-01-31 | 2016-11-29 | Northwestern University | Injectable thermoresponsive polyelectrolytes |
| US9873765B2 (en) | 2011-06-23 | 2018-01-23 | Dsm Ip Assets, B.V. | Biodegradable polyesteramide copolymers for drug delivery |
| JP6045575B2 (ja) | 2011-06-23 | 2016-12-14 | ディーエスエム アイピー アセッツ ビー．ブイ． | 薬物送達のための新規な生分解性ポリエステルアミドコポリマー |
| KR20140050064A (ko) | 2011-07-26 | 2014-04-28 | 더 큐레이터스 오브 더 유니버시티 오브 미주리 | 먹을 수 있는 가공된 육류 |
| EP2596802A1 (en) * | 2011-11-23 | 2013-05-29 | PLS-Design GmbH | Pharmaceutical composition for treatment of allergic reactions |
| US9332779B2 (en) | 2014-02-05 | 2016-05-10 | Modern Meadow, Inc. | Dried food products formed from cultured muscle cells |
| WO2014179615A2 (en) * | 2013-05-01 | 2014-11-06 | Dae Won Park | Biodegradable copolymers, systems including the copolymers, and methods of forming and using same |
| US10364451B2 (en) | 2013-05-30 | 2019-07-30 | Duke University | Polymer conjugates having reduced antigenicity and methods of using the same |
| US10392611B2 (en) | 2013-05-30 | 2019-08-27 | Duke University | Polymer conjugates having reduced antigenicity and methods of using the same |
| WO2015038988A1 (en) | 2013-09-13 | 2015-03-19 | Modern Meadow, Inc. | Edible and animal-product-free microcarriers for engineered meat |
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| ATE287705T1 (de) | 2005-02-15 |
| AU2001294828B2 (en) | 2006-02-09 |
| JP2004525194A (ja) | 2004-08-19 |
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