DE60108651D1 - Wärmegellierende bioabbaubare wässrige polymerlösung - Google Patents
Wärmegellierende bioabbaubare wässrige polymerlösungInfo
- Publication number
- DE60108651D1 DE60108651D1 DE60108651T DE60108651T DE60108651D1 DE 60108651 D1 DE60108651 D1 DE 60108651D1 DE 60108651 T DE60108651 T DE 60108651T DE 60108651 T DE60108651 T DE 60108651T DE 60108651 D1 DE60108651 D1 DE 60108651D1
- Authority
- DE
- Germany
- Prior art keywords
- polymer solution
- aqueous polymer
- block
- bioabcable
- thermalizing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/66—Polyesters containing oxygen in the form of ether groups
- C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Polyesters Or Polycarbonates (AREA)
- Biological Depolymerization Polymers (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Polymerisation Methods In General (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23692600P | 2000-09-28 | 2000-09-28 | |
US236926P | 2000-09-28 | ||
US833460 | 2001-04-11 | ||
US09/833,460 US6841617B2 (en) | 2000-09-28 | 2001-04-11 | Thermogelling biodegradable aqueous polymer solution |
PCT/US2001/030322 WO2002026215A2 (en) | 2000-09-28 | 2001-09-27 | Thermogelling biodegradable aqueous polymer solution |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60108651D1 true DE60108651D1 (de) | 2005-03-03 |
DE60108651T2 DE60108651T2 (de) | 2006-03-30 |
Family
ID=26930226
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60108651T Expired - Lifetime DE60108651T2 (de) | 2000-09-28 | 2001-09-27 | Wärmegelierende, biologisch abbaubare, wäßrige Polymerlösung |
Country Status (8)
Country | Link |
---|---|
US (1) | US6841617B2 (de) |
EP (1) | EP1320359B1 (de) |
JP (1) | JP5031974B2 (de) |
AT (1) | ATE287705T1 (de) |
AU (2) | AU9482801A (de) |
CA (1) | CA2423488C (de) |
DE (1) | DE60108651T2 (de) |
WO (1) | WO2002026215A2 (de) |
Families Citing this family (85)
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US20040228794A1 (en) * | 1998-04-10 | 2004-11-18 | Battelle Memorial Institute | Therapeutic agent carrier compositions |
US20060177416A1 (en) | 2003-10-14 | 2006-08-10 | Medivas, Llc | Polymer particle delivery compositions and methods of use |
US20040185101A1 (en) * | 2001-03-27 | 2004-09-23 | Macromed, Incorporated. | Biodegradable triblock copolymers as solubilizing agents for drugs and method of use thereof |
US7649023B2 (en) | 2002-06-11 | 2010-01-19 | Novartis Ag | Biodegradable block copolymeric compositions for drug delivery |
TWI353854B (en) * | 2002-06-25 | 2011-12-11 | Alza Corp | Short duration depot formulations |
US8986737B2 (en) | 2002-09-05 | 2015-03-24 | Wm. Marsh Rice University | Antibiotic microspheres for treatment and prevention of osteomyelitis and enhancement of bone regrowth |
AU2003272284B2 (en) * | 2002-09-05 | 2009-03-05 | Catherine G. Ambrose | Antibiotic microspheres for treatment of infections and osteomyelitis |
TW200410717A (en) * | 2002-12-31 | 2004-07-01 | Ind Tech Res Inst | Delivery system for control release of temperature sensitive bioactive material |
GB0307011D0 (en) * | 2003-03-27 | 2003-04-30 | Regentec Ltd | Porous matrix |
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US7051654B2 (en) | 2003-05-30 | 2006-05-30 | Clemson University | Ink-jet printing of viable cells |
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DE602004016995D1 (de) * | 2003-06-26 | 2008-11-20 | Control Delivery Sys Inc | In-situ gelierendes arzneimittelabgabesystem |
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US8128952B2 (en) * | 2005-01-12 | 2012-03-06 | Clemson University Research Foundation | Ligand-mediated controlled drug delivery |
US8663686B2 (en) * | 2005-05-09 | 2014-03-04 | University Of Washington | Biodegradable chitosan-PEG compositions and methods of use |
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WO2007038246A2 (en) | 2005-09-22 | 2007-04-05 | Medivas, Llc | Solid polymer delivery compositions and methods for use thereof |
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US6686446B2 (en) | 1998-03-19 | 2004-02-03 | The Regents Of The University Of California | Methods and compositions for controlled polypeptide synthesis |
US6841617B2 (en) | 2000-09-28 | 2005-01-11 | Battelle Memorial Institute | Thermogelling biodegradable aqueous polymer solution |
US6420339B1 (en) | 1998-10-14 | 2002-07-16 | Amgen Inc. | Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility |
AU3867400A (en) | 1999-03-19 | 2000-10-09 | Duke University | Methods of using bioelastomers |
WO2001047501A1 (en) * | 1999-12-29 | 2001-07-05 | Nanodelivery, Inc. | Drug delivery system exhibiting permeability control |
US6444254B1 (en) | 2000-03-03 | 2002-09-03 | Duke University | Microstamping activated polymer surfaces |
US6852834B2 (en) * | 2000-03-20 | 2005-02-08 | Ashutosh Chilkoti | Fusion peptides isolatable by phase transition |
-
2001
- 2001-04-11 US US09/833,460 patent/US6841617B2/en not_active Expired - Lifetime
- 2001-09-27 AU AU9482801A patent/AU9482801A/xx active Pending
- 2001-09-27 CA CA2423488A patent/CA2423488C/en not_active Expired - Lifetime
- 2001-09-27 AU AU2001294828A patent/AU2001294828B2/en not_active Ceased
- 2001-09-27 AT AT01975509T patent/ATE287705T1/de not_active IP Right Cessation
- 2001-09-27 EP EP01975509A patent/EP1320359B1/de not_active Expired - Lifetime
- 2001-09-27 DE DE60108651T patent/DE60108651T2/de not_active Expired - Lifetime
- 2001-09-27 WO PCT/US2001/030322 patent/WO2002026215A2/en active IP Right Grant
- 2001-09-27 JP JP2002530045A patent/JP5031974B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
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DE60108651T2 (de) | 2006-03-30 |
US20020173586A1 (en) | 2002-11-21 |
AU2001294828B2 (en) | 2006-02-09 |
JP2004525194A (ja) | 2004-08-19 |
CA2423488C (en) | 2010-07-13 |
WO2002026215A2 (en) | 2002-04-04 |
EP1320359A2 (de) | 2003-06-25 |
ATE287705T1 (de) | 2005-02-15 |
EP1320359B1 (de) | 2005-01-26 |
US6841617B2 (en) | 2005-01-11 |
AU9482801A (en) | 2002-04-08 |
JP5031974B2 (ja) | 2012-09-26 |
WO2002026215A3 (en) | 2003-01-30 |
CA2423488A1 (en) | 2002-04-04 |
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