DE60108627D1 - Cefalosporin-zwischenprodukte - Google Patents
Cefalosporin-zwischenprodukteInfo
- Publication number
- DE60108627D1 DE60108627D1 DE60108627T DE60108627T DE60108627D1 DE 60108627 D1 DE60108627 D1 DE 60108627D1 DE 60108627 T DE60108627 T DE 60108627T DE 60108627 T DE60108627 T DE 60108627T DE 60108627 D1 DE60108627 D1 DE 60108627D1
- Authority
- DE
- Germany
- Prior art keywords
- compound
- formula
- cephalosporin intermediates
- cephalosporin
- intermediates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0010475.2A GB0010475D0 (en) | 2000-04-28 | 2000-04-28 | Organic compounds |
GB0010475 | 2000-04-28 | ||
PCT/EP2001/004735 WO2001083491A1 (en) | 2000-04-28 | 2001-04-26 | Cephalosporin intermediates |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60108627D1 true DE60108627D1 (de) | 2005-03-03 |
DE60108627T2 DE60108627T2 (de) | 2005-12-29 |
Family
ID=9890746
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60108627T Expired - Lifetime DE60108627T2 (de) | 2000-04-28 | 2001-04-26 | Cefalosporin-zwischenprodukte |
Country Status (12)
Country | Link |
---|---|
US (1) | US6787649B2 (de) |
EP (1) | EP1278754B1 (de) |
JP (1) | JP4990462B2 (de) |
KR (1) | KR100789156B1 (de) |
CN (1) | CN1195761C (de) |
AT (1) | ATE287889T1 (de) |
AU (1) | AU2001260255A1 (de) |
CA (1) | CA2405621C (de) |
DE (1) | DE60108627T2 (de) |
GB (1) | GB0010475D0 (de) |
TW (1) | TWI281920B (de) |
WO (1) | WO2001083491A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101045733B (zh) * | 2007-01-26 | 2011-11-16 | 浙江永宁药业股份有限公司 | 一种头孢替安盐酸盐制备方法 |
CN101633666B (zh) * | 2009-08-26 | 2010-08-18 | 海南永田药物研究院有限公司 | 一种盐酸头孢替安化合物及其新制法 |
CN102190667B (zh) | 2011-03-24 | 2013-05-29 | 海南灵康制药有限公司 | 一种纯化盐酸头孢替安的制法 |
CN102898441A (zh) * | 2012-10-11 | 2013-01-30 | 南通康鑫药业有限公司 | 一种头孢替安的合成方法 |
CN102977123B (zh) * | 2012-12-03 | 2015-04-29 | 邓世碧 | 一种头孢类化合物及其药学可接受盐 |
CN103012436B (zh) * | 2012-12-04 | 2015-07-01 | 山东鑫泉医药有限公司 | 头孢替安盐酸盐的制备方法 |
CN103232477B (zh) * | 2013-05-08 | 2014-04-09 | 四川省惠达药业有限公司 | 一种盐酸头孢替安化合物、其制备方法及其药物组合物 |
CN103601737B (zh) * | 2013-12-04 | 2016-02-03 | 哈药集团制药总厂 | 一种盐酸头孢替安的制备方法 |
CN105125558A (zh) * | 2015-09-18 | 2015-12-09 | 青岛华之草医药科技有限公司 | 一种抗菌药物盐酸头孢替安组合物 |
CN105820162B (zh) * | 2016-05-12 | 2019-01-08 | 浙江永宁药业股份有限公司 | 一种头孢替安工艺杂质的合成方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4341775A (en) * | 1978-09-11 | 1982-07-27 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
EP0088454B1 (de) * | 1979-09-03 | 1986-03-05 | Fujisawa Pharmaceutical Co., Ltd. | Ausgangsprodukte für die Herstellung von Cephalosporinderivaten und Verfahren zu ihrer Herstellung |
NZ208281A (en) | 1983-06-02 | 1986-11-12 | Takeda Chemical Industries Ltd | Cephalosporin ester derivatives and pharmaceutical compositions |
JPS6011490A (ja) * | 1983-06-24 | 1985-01-21 | Sagami Chem Res Center | β−ラクタム誘導体 |
IT1265341B1 (it) | 1993-07-16 | 1996-11-22 | Farmabios Srl | Procedimento per la preparazione di cefalosporine |
AU4123396A (en) * | 1994-12-09 | 1996-06-26 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds and pharmaceutical use thereof |
-
2000
- 2000-04-28 GB GBGB0010475.2A patent/GB0010475D0/en not_active Ceased
-
2001
- 2001-03-28 TW TW090107396A patent/TWI281920B/zh not_active IP Right Cessation
- 2001-04-26 AU AU2001260255A patent/AU2001260255A1/en not_active Abandoned
- 2001-04-26 CA CA002405621A patent/CA2405621C/en not_active Expired - Lifetime
- 2001-04-26 EP EP01933896A patent/EP1278754B1/de not_active Expired - Lifetime
- 2001-04-26 CN CNB01808592XA patent/CN1195761C/zh not_active Expired - Fee Related
- 2001-04-26 US US10/258,624 patent/US6787649B2/en not_active Expired - Fee Related
- 2001-04-26 KR KR1020027013597A patent/KR100789156B1/ko not_active IP Right Cessation
- 2001-04-26 WO PCT/EP2001/004735 patent/WO2001083491A1/en active IP Right Grant
- 2001-04-26 JP JP2001580918A patent/JP4990462B2/ja not_active Expired - Fee Related
- 2001-04-26 DE DE60108627T patent/DE60108627T2/de not_active Expired - Lifetime
- 2001-04-26 AT AT01933896T patent/ATE287889T1/de active
Also Published As
Publication number | Publication date |
---|---|
AU2001260255A1 (en) | 2001-11-12 |
TWI281920B (en) | 2007-06-01 |
US20030153748A1 (en) | 2003-08-14 |
KR100789156B1 (ko) | 2007-12-28 |
WO2001083491A1 (en) | 2001-11-08 |
CN1195761C (zh) | 2005-04-06 |
JP2003531911A (ja) | 2003-10-28 |
GB0010475D0 (en) | 2000-06-14 |
CA2405621C (en) | 2009-12-15 |
DE60108627T2 (de) | 2005-12-29 |
EP1278754A1 (de) | 2003-01-29 |
US6787649B2 (en) | 2004-09-07 |
CA2405621A1 (en) | 2001-11-08 |
ATE287889T1 (de) | 2005-02-15 |
CN1426416A (zh) | 2003-06-25 |
JP4990462B2 (ja) | 2012-08-01 |
EP1278754B1 (de) | 2005-01-26 |
KR20030005274A (ko) | 2003-01-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336 |
|
8328 | Change in the person/name/address of the agent |
Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN |