DE60027890T2 - Streptococcus pneumoniae proteine und impfstoffe - Google Patents

Streptococcus pneumoniae proteine und impfstoffe Download PDF

Info

Publication number
DE60027890T2
DE60027890T2 DE60027890T DE60027890T DE60027890T2 DE 60027890 T2 DE60027890 T2 DE 60027890T2 DE 60027890 T DE60027890 T DE 60027890T DE 60027890 T DE60027890 T DE 60027890T DE 60027890 T2 DE60027890 T2 DE 60027890T2
Authority
DE
Germany
Prior art keywords
polypeptide
polypeptides
vaccine
amino acid
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60027890T
Other languages
German (de)
English (en)
Other versions
DE60027890D1 (de
Inventor
E. John Germantown ADAMOU
H. Gil Rockville CHOI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
MedImmune LLC
Original Assignee
Human Genome Sciences Inc
MedImmune LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc, MedImmune LLC filed Critical Human Genome Sciences Inc
Publication of DE60027890D1 publication Critical patent/DE60027890D1/de
Application granted granted Critical
Publication of DE60027890T2 publication Critical patent/DE60027890T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1275—Streptococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60027890T 1999-06-10 2000-06-09 Streptococcus pneumoniae proteine und impfstoffe Expired - Lifetime DE60027890T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13845399P 1999-06-10 1999-06-10
US138453P 1999-06-10
PCT/US2000/015925 WO2000076540A2 (en) 1999-06-10 2000-06-09 Streptococcus pneumoniae proteins and vaccines

Publications (2)

Publication Number Publication Date
DE60027890D1 DE60027890D1 (de) 2006-06-14
DE60027890T2 true DE60027890T2 (de) 2007-04-19

Family

ID=22482080

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60027890T Expired - Lifetime DE60027890T2 (de) 1999-06-10 2000-06-09 Streptococcus pneumoniae proteine und impfstoffe
DE60045721T Expired - Lifetime DE60045721D1 (de) 1999-06-10 2000-06-09 Streptococcus pneumoniae Proteine und Impfstoffe

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60045721T Expired - Lifetime DE60045721D1 (de) 1999-06-10 2000-06-09 Streptococcus pneumoniae Proteine und Impfstoffe

Country Status (9)

Country Link
EP (2) EP1731166B1 (https=)
JP (1) JP2003501110A (https=)
AT (2) ATE325620T1 (https=)
AU (1) AU777856B2 (https=)
CA (1) CA2371714C (https=)
DE (2) DE60027890T2 (https=)
ES (2) ES2360296T3 (https=)
HK (1) HK1043943A1 (https=)
WO (1) WO2000076540A2 (https=)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6800744B1 (en) 1997-07-02 2004-10-05 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
US7115731B1 (en) 1997-07-02 2006-10-03 sanofi pasteur limited/ sanofi pasteur limiteé Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
US7074415B2 (en) 2000-06-20 2006-07-11 Id Biomedical Corporation Streptococcus antigens
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
EP1456231A2 (en) 2001-12-20 2004-09-15 Shire Biochem Inc. Streptococcus antigens
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
KR101515078B1 (ko) 2005-12-22 2015-04-24 글락소스미스클라인 바이오로지칼즈 에스.에이. 백신
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
CA2690708A1 (en) 2007-06-26 2008-12-31 Glaxosmithkline Biologicals S.A. Vaccine
GB0714963D0 (en) 2007-08-01 2007-09-12 Novartis Ag Compositions comprising antigens
US20110020403A1 (en) 2007-12-13 2011-01-27 Bengt Guss immunizing composition
CN102015651B (zh) 2008-03-03 2014-12-31 Irm责任有限公司 作为tlr活性调节剂的化合物和组合物
ES2553113T3 (es) 2008-04-16 2015-12-04 Glaxosmithkline Biologicals S.A. Vacuna
JP5867952B2 (ja) 2009-06-10 2016-02-24 ノバルティス アーゲー ベンゾナフチリジン含有ワクチン
RU2580299C2 (ru) 2009-06-29 2016-04-10 Дженосеа Биосайенсиз, Инк. Вакцины и композиции, направленные против streptococcus pneumoniae
JO3257B1 (ar) 2009-09-02 2018-09-16 Novartis Ag مركبات وتركيبات كمعدلات لفاعلية tlr
WO2011027222A2 (en) 2009-09-02 2011-03-10 Novartis Ag Immunogenic compositions including tlr activity modulators
US20120237536A1 (en) 2009-09-10 2012-09-20 Novartis Combination vaccines against respiratory tract diseases
WO2011057148A1 (en) 2009-11-05 2011-05-12 Irm Llc Compounds and compositions as tlr-7 activity modulators
BR112012014624A8 (pt) 2009-12-15 2017-12-26 Novartis Ag suspensão homogênea de compostos de imunopotenciação e usos dos destes
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
EA031379B1 (ru) 2010-03-23 2018-12-28 Новартис Аг Соединения (липопептиды на основе цистеина) и композиции в качестве агонистов tlr2, применяемые для лечения инфекционных, воспалительных, респираторных и других заболеваний
WO2012072769A1 (en) 2010-12-01 2012-06-07 Novartis Ag Pneumococcal rrgb epitopes and clade combinations
WO2012100233A1 (en) 2011-01-20 2012-07-26 Genocea Biosciences, Inc. Vaccines and compositions against streptococcus pneumoniae
CN103533953A (zh) 2011-05-17 2014-01-22 葛兰素史密丝克莱恩生物有限公司 针对肺炎链球菌的疫苗
JP2015510872A (ja) 2012-03-07 2015-04-13 ノバルティス アーゲー Ｓｔｒｅｐｔｏｃｏｃｃｕｓｐｎｅｕｍｏｎｉａｅ抗原の増強された製剤
BR112015018014A2 (pt) 2013-02-01 2017-07-11 Glaxosmithkline Biologicals Sa liberação intradérmica de composições imunológicas compreendendo agonistas do receptor do tipo toll
GB201711635D0 (en) 2017-07-19 2017-08-30 Glaxosmithkline Biologicals Sa Immunogenic composition
JP7362667B2 (ja) 2018-02-12 2023-10-17 イニミューン・コーポレーション Ｔｏｌｌ様受容体リガンド
JP2023547677A (ja) 2020-11-04 2023-11-13 エリゴ・バイオサイエンス キューティバクテリウム・アクネス組換えファージ、その産生方法及び使用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4469026B2 (ja) * 1996-10-31 2010-05-26 ヒューマン ジノーム サイエンシーズ，インコーポレイテッド Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ｐｎｅｕｍｏｎｉａｅの抗原およびワクチン
CN1318103A (zh) * 1998-07-27 2001-10-17 微生物技术有限公司 肺炎链球菌的核酸和蛋白质

Also Published As

Publication number Publication date
DE60045721D1 (de) 2011-04-21
CA2371714A1 (en) 2000-12-21
WO2000076540A2 (en) 2000-12-21
DE60027890D1 (de) 2006-06-14
EP1731166B1 (en) 2011-03-09
ATE325620T1 (de) 2006-06-15
HK1043943A1 (zh) 2002-10-04
JP2003501110A (ja) 2003-01-14
AU777856B2 (en) 2004-11-04
EP1185297A2 (en) 2002-03-13
ATE500843T1 (de) 2011-03-15
WO2000076540A3 (en) 2001-02-08
EP1731166A2 (en) 2006-12-13
ES2264419T3 (es) 2007-01-01
AU5477800A (en) 2001-01-02
EP1731166A3 (en) 2007-02-21
CA2371714C (en) 2012-12-04
ES2360296T3 (es) 2011-06-02
EP1185297B1 (en) 2006-05-10

Similar Documents

Publication Publication Date Title
DE60027890T2 (de) Streptococcus pneumoniae proteine und impfstoffe
KR101170203B1 (ko) 신규한 스트렙토코커스 항원
DE69737125T2 (de) Streptococcus pneumoniae antigene und impfstoffe
EP2050464B1 (en) Streptococcus pneumoniae proteins and immunogenic fragments for vaccines
KR20010034518A (ko) 그룹 ｂ 스트렙토코커스 항원
US6689369B2 (en) Immunogenic pneumococcal protein and vaccine compositions thereof
US6716432B1 (en) Pneumolysin mutants and pneumococcal vaccines made therefrom
DE69836520T2 (de) Clostridium perfringens Impfstoff
AU2001255772A1 (en) Immunogenic pneumococcal protein and vaccine compositions thereof
DE69836744T2 (de) Gruppe a streptokokken-impfstoff
DE69634077T2 (de) Haemophilus Adhäsionsproeine
US7132107B2 (en) Streptococcus pneumoniae proteins and vaccines
DE69333365T2 (de) Lipoprotein a der äusseren membran von actinobacillus pleuropneumonia und dessen verwendung
DE60030060T2 (de) Mycoplasma hyopneumoniae- Antigen mhp3, dafür kodierendes Gen und ihre Verwendungen
DE69322773T2 (de) Haemophilus somnus immunogene proteine
JP4749641B2 (ja) ワクチン用の肺炎球菌タンパク質の相同体および断片
DE60034463T2 (de) Basb119 polypeptid und polynukleotid aus moraxella catarrhalis
DE60127401T2 (de) Milchvieh immunisierung mit mig protein
AU2008229967B2 (en) Novel streptococcus antigens

Legal Events

Date Code Title Description
8364 No opposition during term of opposition