DE60021068D1 - Gewebeinhibitor der matrix-metalproteinase typ 1 (timp-1) als krebsmarker - Google Patents

Gewebeinhibitor der matrix-metalproteinase typ 1 (timp-1) als krebsmarker

Info

Publication number
DE60021068D1
DE60021068D1 DE60021068T DE60021068T DE60021068D1 DE 60021068 D1 DE60021068 D1 DE 60021068D1 DE 60021068 T DE60021068 T DE 60021068T DE 60021068 T DE60021068 T DE 60021068T DE 60021068 D1 DE60021068 D1 DE 60021068D1
Authority
DE
Germany
Prior art keywords
timp
matrix metal
cancer marker
tissue inhibitor
metal proteinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60021068T
Other languages
English (en)
Other versions
DE60021068T2 (de
Inventor
Mads Holten-Andersen
Ross Stephens
Hans Nielsen
Ib Christensen
Nils Bruenner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RIGSHOSPITALET COPENHAGEN
Original Assignee
RIGSHOSPITALET COPENHAGEN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RIGSHOSPITALET COPENHAGEN filed Critical RIGSHOSPITALET COPENHAGEN
Application granted granted Critical
Publication of DE60021068D1 publication Critical patent/DE60021068D1/de
Publication of DE60021068T2 publication Critical patent/DE60021068T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57415—Specifically defined cancers of breast
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96486—Metalloendopeptidases (3.4.24)
    • G01N2333/96491—Metalloendopeptidases (3.4.24) with definite EC number
    • G01N2333/96494—Matrix metalloproteases, e. g. 3.4.24.7

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60021068T 1999-04-09 2000-04-10 Gewebeinhibitor der matrix-metalproteinase typ 1 (timp-1) als krebsmarker Expired - Lifetime DE60021068T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA199900476 1999-04-09
DK990476 1999-04-09
PCT/DK2000/000170 WO2000062070A2 (en) 1999-04-09 2000-04-10 Tissue inhibitor of matrix metalloproteinases type-1 (timp-1) as a cancer marker

Publications (2)

Publication Number Publication Date
DE60021068D1 true DE60021068D1 (de) 2005-08-04
DE60021068T2 DE60021068T2 (de) 2006-05-18

Family

ID=8093987

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60021068T Expired - Lifetime DE60021068T2 (de) 1999-04-09 2000-04-10 Gewebeinhibitor der matrix-metalproteinase typ 1 (timp-1) als krebsmarker

Country Status (11)

Country Link
US (6) US7108983B1 (de)
EP (2) EP1171771B1 (de)
JP (2) JP4638608B2 (de)
AT (1) ATE298890T1 (de)
AU (1) AU771309B2 (de)
CA (2) CA2652131A1 (de)
DE (1) DE60021068T2 (de)
ES (1) ES2244417T3 (de)
NO (1) NO329725B1 (de)
NZ (1) NZ515311A (de)
WO (1) WO2000062070A2 (de)

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US20060154245A1 (en) * 1999-04-09 2006-07-13 Rigshospitalet Method for detecting, screening and/or montoring a cancer in individual
DE60021068T2 (de) 1999-04-09 2006-05-18 Rigshospitalet Gewebeinhibitor der matrix-metalproteinase typ 1 (timp-1) als krebsmarker
US7374886B2 (en) 1999-04-09 2008-05-20 Rigshospitalet Tissue inhibitor of matrix metalloproteinases type-1 (TIMP-1) as a cancer marker and postoperative marker for minimal residual disease or recurrent disease in patients with a prior history of cancer
CA2445168A1 (en) 2001-04-24 2002-10-31 Bayer Corporation Human timp-1 antibodies
AU2003226925A1 (en) * 2002-04-08 2003-10-27 Hvidovre Hospital Timp-1 as a postoperative marker for recurrent cancer
US20060014224A1 (en) * 2002-09-26 2006-01-19 Hvidovre Hospital Method for detecting, screening and/or monitoring a cancer in an individual
CA2526878A1 (en) * 2003-04-08 2004-10-21 Colotech A/S A method for detection of colorectal cancer in human samples
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FR2919061B1 (fr) * 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage de la plastine-i pour le diagnostic in vitro du cancer colorectal.
FR2919060B1 (fr) 2007-07-19 2012-11-30 Biomerieux Sa Procede de dosage de l'ezrine pour le diagnostic in vitro du cancer colorectal.
FR2919064B1 (fr) * 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage de l'apolipoproteine all pour le diagnostic in vitro du cancer colorectal
FR2919062B1 (fr) * 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage de l'aminoacylase 1 pour le diagnostic in vitro du cancer colorectal.
FR2919063B1 (fr) * 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage du leucocyte elastase inhibitor pour le diagnostic in vitro du cancer colorectal.
EP2238455A4 (de) * 2008-01-18 2011-03-02 Vatrix Medical Inc Diagnostische biomarker für gefässaneurysma
US8697384B2 (en) 2008-01-23 2014-04-15 Herlev Hospital YKL-40 as a general marker for non-specific disease
JP2011523067A (ja) * 2008-06-11 2011-08-04 アーゲ ブルナー，ニルス ネオアジュバントおよびアジュバント全身性抗癌治療のための結腸直腸癌患者の選択
FR2933773B1 (fr) 2008-07-10 2013-02-15 Biomerieux Sa Procede de dosage de la proteine disulfide isomerase pour le diagnostic in vitro du cancer colorectal
US8580520B2 (en) 2008-09-15 2013-11-12 Herlev Hospital YKL-40 as a marker for gastrointestinal cancers
DE102009015784A1 (de) * 2009-03-31 2010-12-02 Siemens Aktiengesellschaft In-vitro-Verfahren zur Diagnostik von Tumorerkrankungen
US9141756B1 (en) 2010-07-20 2015-09-22 University Of Southern California Multi-scale complex systems transdisciplinary analysis of response to therapy
JP6182308B2 (ja) * 2012-11-13 2017-08-16 株式会社エイアンドティー 前立腺癌の鑑別診断に用いるための泳動波形データの処理方法
US9689874B2 (en) 2015-04-10 2017-06-27 Applied Proteomics, Inc. Protein biomarker panels for detecting colorectal cancer and advanced adenoma
US20210148894A1 (en) * 2018-04-13 2021-05-20 Bionomics Limited Method of monitoring response to a treatment
WO2021039616A1 (ja) * 2019-08-23 2021-03-04 大日本住友製薬株式会社 併用療法及びその有効性を示すバイオマーカー

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US20060014224A1 (en) * 2002-09-26 2006-01-19 Hvidovre Hospital Method for detecting, screening and/or monitoring a cancer in an individual
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CN1972703A (zh) * 2004-03-30 2007-05-30 丹麦皇家兽医和农业学院 通过阻断和检测蛋白酶抑制剂改进癌症的治疗和癌症治疗效率的预测

Also Published As

Publication number Publication date
US7108983B1 (en) 2006-09-19
NO20014869D0 (no) 2001-10-05
US20080261246A1 (en) 2008-10-23
US20110294148A1 (en) 2011-12-01
CA2366682A1 (en) 2000-10-19
NO20014869L (no) 2001-12-04
NZ515311A (en) 2002-11-26
US20090035794A1 (en) 2009-02-05
ATE298890T1 (de) 2005-07-15
EP1619206A2 (de) 2006-01-25
EP1171771B1 (de) 2005-06-29
AU771309B2 (en) 2004-03-18
US20110060529A1 (en) 2011-03-10
EP1619206A3 (de) 2006-02-15
ES2244417T3 (es) 2005-12-16
JP2002541481A (ja) 2002-12-03
US7807379B2 (en) 2010-10-05
EP1171771A2 (de) 2002-01-16
DE60021068T2 (de) 2006-05-18
JP4638608B2 (ja) 2011-02-23
WO2000062070A3 (en) 2001-01-25
NO329725B1 (no) 2010-12-06
CA2366682C (en) 2009-06-23
JP2010266455A (ja) 2010-11-25
AU3655600A (en) 2000-11-14
US20070020707A1 (en) 2007-01-25
WO2000062070A2 (en) 2000-10-19
CA2652131A1 (en) 2000-10-19

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