DE60016622D1 - Hydroxamsäurederivat als inhibitor der produktion von löslichem menschlichem cd23 - Google Patents

Hydroxamsäurederivat als inhibitor der produktion von löslichem menschlichem cd23

Info

Publication number
DE60016622D1
DE60016622D1 DE2000616622 DE60016622T DE60016622D1 DE 60016622 D1 DE60016622 D1 DE 60016622D1 DE 2000616622 DE2000616622 DE 2000616622 DE 60016622 T DE60016622 T DE 60016622T DE 60016622 D1 DE60016622 D1 DE 60016622D1
Authority
DE
Germany
Prior art keywords
hydroxamedic
inhibitor
derivative
production
soluble human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE2000616622
Other languages
English (en)
Other versions
DE60016622T2 (de
Inventor
Andrew Faller
John Gerard Ward
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of DE60016622D1 publication Critical patent/DE60016622D1/de
Application granted granted Critical
Publication of DE60016622T2 publication Critical patent/DE60016622T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
DE60016622T 1999-10-27 2000-10-25 Hydroxamsäurederivat als inhibitor der produktion von löslichem menschlichem cd23 Expired - Lifetime DE60016622T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9925470.8A GB9925470D0 (en) 1999-10-27 1999-10-27 Novel compounds
GB9925470 1999-10-27
PCT/EP2000/010649 WO2001030747A1 (en) 1999-10-27 2000-10-25 Hydroxamic acid derivative as inhibitor of the formation of soluble human cd23

Publications (2)

Publication Number Publication Date
DE60016622D1 true DE60016622D1 (de) 2005-01-13
DE60016622T2 DE60016622T2 (de) 2005-11-03

Family

ID=10863507

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60016622T Expired - Lifetime DE60016622T2 (de) 1999-10-27 2000-10-25 Hydroxamsäurederivat als inhibitor der produktion von löslichem menschlichem cd23

Country Status (32)

Country Link
US (2) US6673965B1 (de)
EP (1) EP1224164B1 (de)
JP (1) JP3922431B2 (de)
KR (1) KR20020044578A (de)
CN (1) CN1182107C (de)
AR (1) AR026244A1 (de)
AT (1) ATE284382T1 (de)
AU (1) AU766072B2 (de)
BR (1) BR0015082A (de)
CA (1) CA2389319A1 (de)
CO (1) CO5261576A1 (de)
CZ (1) CZ20021424A3 (de)
DE (1) DE60016622T2 (de)
DK (1) DK1224164T3 (de)
ES (1) ES2233474T3 (de)
GB (1) GB9925470D0 (de)
GC (1) GC0000142A (de)
HK (1) HK1049146A1 (de)
HU (1) HUP0203270A3 (de)
IL (1) IL149364A0 (de)
MX (1) MXPA02004228A (de)
MY (1) MY133601A (de)
NO (1) NO20021965L (de)
NZ (1) NZ518566A (de)
PE (1) PE20010898A1 (de)
PL (1) PL356524A1 (de)
PT (1) PT1224164E (de)
SI (1) SI1224164T1 (de)
TW (1) TW561141B (de)
UY (1) UY26416A1 (de)
WO (1) WO2001030747A1 (de)
ZA (1) ZA200203255B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2334636A2 (de) * 2008-09-19 2011-06-22 Pfizer Inc. Als antibakterielle mittel geeignete hydroxaminsäurederivate
US8945575B2 (en) 2009-12-01 2015-02-03 Trustees Of Boston University Treatment of IgE-mediated disease
WO2011073845A1 (en) 2009-12-16 2011-06-23 Pfizer Inc. N-linked hydroxamic acid derivatives useful as antibacterial agents
CN104529883A (zh) 2011-03-07 2015-04-22 辉瑞大药厂 可用作抗菌剂的氟吡啶酮衍生物
AU2012238374B2 (en) 2011-04-08 2015-04-02 Pfizer Inc. Isoxazole derivatives useful as antibacterial agents
CN103492368A (zh) 2011-04-08 2014-01-01 辉瑞大药厂 用作抗菌剂的咪唑、吡唑和噻唑衍生物
EP2525213A1 (de) * 2011-05-16 2012-11-21 Renishaw plc Spektroskopievorrichtung und Verfahren zur Bestimmung der in einer Probe vorkommenden Komponenten

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9513331D0 (en) 1995-06-30 1995-09-06 British Biotech Pharm Matrix metalloproteinase inhibitors
GB9813451D0 (en) * 1998-06-22 1998-08-19 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
US6673965B1 (en) 2004-01-06
SI1224164T1 (en) 2005-06-30
NO20021965L (no) 2002-06-13
HUP0203270A2 (hu) 2003-02-28
NO20021965D0 (no) 2002-04-25
AR026244A1 (es) 2003-02-05
WO2001030747A1 (en) 2001-05-03
DK1224164T3 (da) 2005-03-29
CO5261576A1 (es) 2003-03-31
BR0015082A (pt) 2003-04-15
IL149364A0 (en) 2002-11-10
AU1389501A (en) 2001-05-08
JP2003512450A (ja) 2003-04-02
US20040077727A1 (en) 2004-04-22
UY26416A1 (es) 2001-05-31
PE20010898A1 (es) 2001-10-13
PT1224164E (pt) 2005-04-29
CN1182107C (zh) 2004-12-29
AU766072B2 (en) 2003-10-09
CN1411436A (zh) 2003-04-16
KR20020044578A (ko) 2002-06-15
ES2233474T3 (es) 2005-06-16
MY133601A (en) 2007-11-30
EP1224164A1 (de) 2002-07-24
HUP0203270A3 (en) 2003-11-28
NZ518566A (en) 2004-02-27
PL356524A1 (en) 2004-06-28
JP3922431B2 (ja) 2007-05-30
EP1224164B1 (de) 2004-12-08
ZA200203255B (en) 2003-03-20
CA2389319A1 (en) 2001-05-03
ATE284382T1 (de) 2004-12-15
CZ20021424A3 (cs) 2002-09-11
DE60016622T2 (de) 2005-11-03
HK1049146A1 (en) 2003-05-02
TW561141B (en) 2003-11-11
GC0000142A (en) 2005-06-29
MXPA02004228A (es) 2002-10-17
GB9925470D0 (en) 1999-12-29

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Legal Events

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