AR026244A1 - Compuestos - Google Patents

Compuestos

Info

Publication number
AR026244A1
AR026244A1 ARP000105622A ARP000105622A AR026244A1 AR 026244 A1 AR026244 A1 AR 026244A1 AR P000105622 A ARP000105622 A AR P000105622A AR P000105622 A ARP000105622 A AR P000105622A AR 026244 A1 AR026244 A1 AR 026244A1
Authority
AR
Argentina
Prior art keywords
compounds
naphthylmethyl
isopropyl
butyl
methyl
Prior art date
Application number
ARP000105622A
Other languages
English (en)
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of AR026244A1 publication Critical patent/AR026244A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Un compuesto de formula (1) donde: R es isopropilo; n es O; R1 es naftilmetilo; R2 es t-butilo; y R3 es metilo; es util en el tratamiento de trastornosmediados por s-CD23.
ARP000105622A 1999-10-27 2000-10-25 Compuestos AR026244A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9925470.8A GB9925470D0 (en) 1999-10-27 1999-10-27 Novel compounds

Publications (1)

Publication Number Publication Date
AR026244A1 true AR026244A1 (es) 2003-02-05

Family

ID=10863507

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000105622A AR026244A1 (es) 1999-10-27 2000-10-25 Compuestos

Country Status (32)

Country Link
US (2) US6673965B1 (es)
EP (1) EP1224164B1 (es)
JP (1) JP3922431B2 (es)
KR (1) KR20020044578A (es)
CN (1) CN1182107C (es)
AR (1) AR026244A1 (es)
AT (1) ATE284382T1 (es)
AU (1) AU766072B2 (es)
BR (1) BR0015082A (es)
CA (1) CA2389319A1 (es)
CO (1) CO5261576A1 (es)
CZ (1) CZ20021424A3 (es)
DE (1) DE60016622T2 (es)
DK (1) DK1224164T3 (es)
ES (1) ES2233474T3 (es)
GB (1) GB9925470D0 (es)
GC (1) GC0000142A (es)
HK (1) HK1049146A1 (es)
HU (1) HUP0203270A3 (es)
IL (1) IL149364A0 (es)
MX (1) MXPA02004228A (es)
MY (1) MY133601A (es)
NO (1) NO20021965L (es)
NZ (1) NZ518566A (es)
PE (1) PE20010898A1 (es)
PL (1) PL356524A1 (es)
PT (1) PT1224164E (es)
SI (1) SI1224164T1 (es)
TW (1) TW561141B (es)
UY (1) UY26416A1 (es)
WO (1) WO2001030747A1 (es)
ZA (1) ZA200203255B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5524215B2 (ja) * 2008-09-19 2014-06-18 ファイザー・インク 抗菌剤として有用なヒドロキサム酸誘導体
US8945575B2 (en) 2009-12-01 2015-02-03 Trustees Of Boston University Treatment of IgE-mediated disease
PL2512474T3 (pl) 2009-12-16 2015-03-31 Pfizer N-przyłączone pochodne kwasu hydroksamowego użyteczne jako środki przeciwbakteryjne
UA107423C2 (en) 2011-03-07 2014-12-25 Pfizer Fluoro-pyridinone derivatives useful as antibacterial agents
DK2694488T3 (en) 2011-04-08 2014-12-15 Pfizer Isoxazole derivatives useful as antibacterial SUBSTANCES
JP2014514299A (ja) 2011-04-08 2014-06-19 ファイザー・インク 抗菌剤として有用なイミダゾール、ピラゾールおよびトリアゾール誘導体
EP2525213A1 (en) * 2011-05-16 2012-11-21 Renishaw plc Spectroscopic apparatus and methods for determining components present in a sample

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9513331D0 (en) 1995-06-30 1995-09-06 British Biotech Pharm Matrix metalloproteinase inhibitors
GB9813451D0 (en) * 1998-06-22 1998-08-19 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
BR0015082A (pt) 2003-04-15
CO5261576A1 (es) 2003-03-31
ATE284382T1 (de) 2004-12-15
JP3922431B2 (ja) 2007-05-30
ES2233474T3 (es) 2005-06-16
MY133601A (en) 2007-11-30
EP1224164A1 (en) 2002-07-24
GC0000142A (en) 2005-06-29
GB9925470D0 (en) 1999-12-29
DE60016622T2 (de) 2005-11-03
HUP0203270A2 (hu) 2003-02-28
CZ20021424A3 (cs) 2002-09-11
PE20010898A1 (es) 2001-10-13
DE60016622D1 (de) 2005-01-13
NZ518566A (en) 2004-02-27
US20040077727A1 (en) 2004-04-22
WO2001030747A1 (en) 2001-05-03
NO20021965D0 (no) 2002-04-25
MXPA02004228A (es) 2002-10-17
TW561141B (en) 2003-11-11
CN1182107C (zh) 2004-12-29
EP1224164B1 (en) 2004-12-08
SI1224164T1 (en) 2005-06-30
CA2389319A1 (en) 2001-05-03
US6673965B1 (en) 2004-01-06
DK1224164T3 (da) 2005-03-29
CN1411436A (zh) 2003-04-16
AU766072B2 (en) 2003-10-09
JP2003512450A (ja) 2003-04-02
HUP0203270A3 (en) 2003-11-28
AU1389501A (en) 2001-05-08
NO20021965L (no) 2002-06-13
IL149364A0 (en) 2002-11-10
PL356524A1 (en) 2004-06-28
ZA200203255B (en) 2003-03-20
UY26416A1 (es) 2001-05-31
KR20020044578A (ko) 2002-06-15
PT1224164E (pt) 2005-04-29
HK1049146A1 (en) 2003-05-02

Similar Documents

Publication Publication Date Title
NZ514711A (en) Compounds useful as anti-inflammatory agents
ATE487493T1 (de) Azolsäure-derivate, allein oder kombiniert, zur behandlung von diabetes und dyslipidaemien; und zur behandlung von malignen erkrankungen
ATE346039T1 (de) Sulfonamido-substituierte verbrückte bicycloalkylderivative
ATE287096T1 (de) Elektrochrome vorrichtung
DK1109812T3 (da) Pyrrolobenzodiazepiner
CY1111867T1 (el) Ενωση ενεργοποιησης ppar και φαρμακευτικη συνθεση που περιεχει αυτη
IS6309A (is) Kínasólínafleiður
PE20040728A1 (es) Inhibidores de caspasa
DE60317208D1 (de) Pleuromutilinderivate als antimikrobielle mittel
MXPA05007296A (es) Compuestos de (2-carboxamido)(3-amino)tiofeno.
ATE316962T1 (de) Pyrimidin-derivate als selective inhibitoren von cox-2
NZ516525A (en) Orally active androgens
ATE402175T1 (de) 4-oxo-1-(3-substituiertesphenyl)-1,4-dihydro-1, - naphthyridin-3-carbonsäureamide alsphoshodiesterase-4-inhibitoren
DE60221508D1 (de) Aminosäurederivate als hiv-protease-inhibitoren
ID23053A (id) Karboksamida yang digunakan sebagai agonis 5-ht <if>
ATE273970T1 (de) N-acyl und n-aroyl aralkylamide
AR026244A1 (es) Compuestos
UA83266C2 (en) Oxazole derivatives of tetracyclines
ATE270273T1 (de) Substituierte azetidinone als entzüngdungshemmende und antidegenerative wirkstoffe
DE69837597D1 (de) 4-Organothio-2-Cyclopentenonen und 3-Organothio-2-Cyclopentanonen, deren Herstellungsverfahren und pharmazeutischen Anwendungen
DE60121048D1 (de) PYRAZINOi1'2':1,6öPYRIDOi3,4-BöINDOLDERIVATE
DE60017374D1 (de) Antibakterielle mittel
AR027349A1 (es) Derivados de amidas heterociclicas
DE60013515D1 (de) 4-Arylpiperidinderivate zur Behandlung von Pruritus
DK1049672T3 (da) Azetidincarboxamid-derivater til behandling af CNS-lidelser

Legal Events

Date Code Title Description
FA Abandonment or withdrawal