HUP0203270A3 - Hydroxamic acid derivative as inhibitor of the formation of human cd23, process for its preparation and pharmaceutical compositions containing the same - Google Patents
Hydroxamic acid derivative as inhibitor of the formation of human cd23, process for its preparation and pharmaceutical compositions containing the sameInfo
- Publication number
- HUP0203270A3 HUP0203270A3 HU0203270A HUP0203270A HUP0203270A3 HU P0203270 A3 HUP0203270 A3 HU P0203270A3 HU 0203270 A HU0203270 A HU 0203270A HU P0203270 A HUP0203270 A HU P0203270A HU P0203270 A3 HUP0203270 A3 HU P0203270A3
- Authority
- HU
- Hungary
- Prior art keywords
- inhibitor
- human
- formation
- preparation
- pharmaceutical compositions
- Prior art date
Links
- NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9925470.8A GB9925470D0 (en) | 1999-10-27 | 1999-10-27 | Novel compounds |
| PCT/EP2000/010649 WO2001030747A1 (en) | 1999-10-27 | 2000-10-25 | Hydroxamic acid derivative as inhibitor of the formation of soluble human cd23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0203270A2 HUP0203270A2 (hu) | 2003-02-28 |
| HUP0203270A3 true HUP0203270A3 (en) | 2003-11-28 |
Family
ID=10863507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0203270A HUP0203270A3 (en) | 1999-10-27 | 2000-10-25 | Hydroxamic acid derivative as inhibitor of the formation of human cd23, process for its preparation and pharmaceutical compositions containing the same |
Country Status (32)
| Country | Link |
|---|---|
| US (2) | US6673965B1 (hu) |
| EP (1) | EP1224164B1 (hu) |
| JP (1) | JP3922431B2 (hu) |
| KR (1) | KR20020044578A (hu) |
| CN (1) | CN1182107C (hu) |
| AR (1) | AR026244A1 (hu) |
| AT (1) | ATE284382T1 (hu) |
| AU (1) | AU766072B2 (hu) |
| BR (1) | BR0015082A (hu) |
| CA (1) | CA2389319A1 (hu) |
| CO (1) | CO5261576A1 (hu) |
| CZ (1) | CZ20021424A3 (hu) |
| DE (1) | DE60016622T2 (hu) |
| DK (1) | DK1224164T3 (hu) |
| ES (1) | ES2233474T3 (hu) |
| GB (1) | GB9925470D0 (hu) |
| GC (1) | GC0000142A (hu) |
| HK (1) | HK1049146A1 (hu) |
| HU (1) | HUP0203270A3 (hu) |
| IL (1) | IL149364A0 (hu) |
| MX (1) | MXPA02004228A (hu) |
| MY (1) | MY133601A (hu) |
| NO (1) | NO20021965L (hu) |
| NZ (1) | NZ518566A (hu) |
| PE (1) | PE20010898A1 (hu) |
| PL (1) | PL356524A1 (hu) |
| PT (1) | PT1224164E (hu) |
| SI (1) | SI1224164T1 (hu) |
| TW (1) | TW561141B (hu) |
| UY (1) | UY26416A1 (hu) |
| WO (1) | WO2001030747A1 (hu) |
| ZA (1) | ZA200203255B (hu) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8722686B2 (en) * | 2008-09-19 | 2014-05-13 | Pfizer Inc. | Hydroxamic acid derivatives useful as antibacterial agents |
| US8945575B2 (en) | 2009-12-01 | 2015-02-03 | Trustees Of Boston University | Treatment of IgE-mediated disease |
| US8664401B2 (en) | 2009-12-16 | 2014-03-04 | Pfizer Inc. | N-linked hydroxamic acid derivatives useful as antibacterial agents |
| CN104529883A (zh) | 2011-03-07 | 2015-04-22 | 辉瑞大药厂 | 可用作抗菌剂的氟吡啶酮衍生物 |
| CA2830866A1 (en) | 2011-04-08 | 2012-10-11 | Pfizer Inc. | Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents |
| US8748466B2 (en) | 2011-04-08 | 2014-06-10 | Pfizer Inc. | Isoxazole derivatives useful as antibacterial agents |
| EP2525213A1 (en) * | 2011-05-16 | 2012-11-21 | Renishaw plc | Spectroscopic apparatus and methods for determining components present in a sample |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9513331D0 (en) | 1995-06-30 | 1995-09-06 | British Biotech Pharm | Matrix metalloproteinase inhibitors |
| GB9813451D0 (en) * | 1998-06-22 | 1998-08-19 | Smithkline Beecham Plc | Novel compounds |
-
1999
- 1999-10-27 GB GBGB9925470.8A patent/GB9925470D0/en not_active Ceased
-
2000
- 2000-10-25 DK DK00975954T patent/DK1224164T3/da active
- 2000-10-25 KR KR1020027005340A patent/KR20020044578A/ko not_active Application Discontinuation
- 2000-10-25 IL IL14936400A patent/IL149364A0/xx unknown
- 2000-10-25 CA CA002389319A patent/CA2389319A1/en not_active Abandoned
- 2000-10-25 EP EP00975954A patent/EP1224164B1/en not_active Expired - Lifetime
- 2000-10-25 JP JP2001533102A patent/JP3922431B2/ja not_active Expired - Fee Related
- 2000-10-25 US US10/111,209 patent/US6673965B1/en not_active Expired - Fee Related
- 2000-10-25 MX MXPA02004228A patent/MXPA02004228A/es active IP Right Grant
- 2000-10-25 UY UY26416A patent/UY26416A1/es not_active Application Discontinuation
- 2000-10-25 ES ES00975954T patent/ES2233474T3/es not_active Expired - Lifetime
- 2000-10-25 AU AU13895/01A patent/AU766072B2/en not_active Ceased
- 2000-10-25 NZ NZ518566A patent/NZ518566A/en unknown
- 2000-10-25 PL PL00356524A patent/PL356524A1/xx unknown
- 2000-10-25 GC GCP2000972 patent/GC0000142A/xx active
- 2000-10-25 DE DE60016622T patent/DE60016622T2/de not_active Expired - Lifetime
- 2000-10-25 WO PCT/EP2000/010649 patent/WO2001030747A1/en active IP Right Grant
- 2000-10-25 AR ARP000105622A patent/AR026244A1/es not_active Application Discontinuation
- 2000-10-25 HU HU0203270A patent/HUP0203270A3/hu unknown
- 2000-10-25 CZ CZ20021424A patent/CZ20021424A3/cs unknown
- 2000-10-25 SI SI200030603T patent/SI1224164T1/xx unknown
- 2000-10-25 CN CNB008173680A patent/CN1182107C/zh not_active Expired - Fee Related
- 2000-10-25 AT AT00975954T patent/ATE284382T1/de not_active IP Right Cessation
- 2000-10-25 MY MYPI20005012A patent/MY133601A/en unknown
- 2000-10-25 BR BR0015082-7A patent/BR0015082A/pt not_active IP Right Cessation
- 2000-10-25 PT PT00975954T patent/PT1224164E/pt unknown
- 2000-10-26 TW TW089122497A patent/TW561141B/zh active
- 2000-10-26 CO CO00081571A patent/CO5261576A1/es not_active Application Discontinuation
- 2000-10-27 PE PE2000001156A patent/PE20010898A1/es not_active Application Discontinuation
-
2002
- 2002-04-24 ZA ZA200203255A patent/ZA200203255B/en unknown
- 2002-04-25 NO NO20021965A patent/NO20021965L/no unknown
- 2002-12-19 HK HK02109235A patent/HK1049146A1/xx not_active IP Right Cessation
-
2003
- 2003-10-03 US US10/678,679 patent/US20040077727A1/en not_active Abandoned
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