DE60008545T2 - Antibakterielle heterobicyclisch substituierte phenyloxazolidinone - Google Patents
Antibakterielle heterobicyclisch substituierte phenyloxazolidinone Download PDFInfo
- Publication number
- DE60008545T2 DE60008545T2 DE60008545T DE60008545T DE60008545T2 DE 60008545 T2 DE60008545 T2 DE 60008545T2 DE 60008545 T DE60008545 T DE 60008545T DE 60008545 T DE60008545 T DE 60008545T DE 60008545 T2 DE60008545 T2 DE 60008545T2
- Authority
- DE
- Germany
- Prior art keywords
- alkyl
- mmol
- carbon atoms
- group
- added
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 0 C*C1(C)/C=C/C(/*(C[C@](C*(C)C)O2)C2=O)=C/C(C)(*)/C=C1 Chemical compound C*C1(C)/C=C/C(/*(C[C@](C*(C)C)O2)C2=O)=C/C(C)(*)/C=C1 0.000 description 7
- SCLGTVLEHSOCTO-MRNPHLECSA-N CC(NC[C@@H](CN1c2ccc(CC(CC3)Cc4c3cccc4)c(F)c2)OC1=O)=O Chemical compound CC(NC[C@@H](CN1c2ccc(CC(CC3)Cc4c3cccc4)c(F)c2)OC1=O)=O SCLGTVLEHSOCTO-MRNPHLECSA-N 0.000 description 1
- YAYBNHQJBPSZSU-AWEZNQCLSA-O COC(NC[C@@H](CN1c(cc2F)ccc2N2Cc3ncccc3C2)[OH+]C1=O)=O Chemical compound COC(NC[C@@H](CN1c(cc2F)ccc2N2Cc3ncccc3C2)[OH+]C1=O)=O YAYBNHQJBPSZSU-AWEZNQCLSA-O 0.000 description 1
- YLVMFNOYWSUKBG-KRWDZBQOSA-N O=C(C1CC1)NC[C@@H](CN1c(cc2)cc(F)c2N(C2)Cc3c2ccnc3)OC1=O Chemical compound O=C(C1CC1)NC[C@@H](CN1c(cc2)cc(F)c2N(C2)Cc3c2ccnc3)OC1=O YLVMFNOYWSUKBG-KRWDZBQOSA-N 0.000 description 1
- JDXHDLULUWEYIU-UHFFFAOYSA-N [O-][N+](c(cc1)cc(F)c1N1Cc2ncccc2C1)=O Chemical compound [O-][N+](c(cc1)cc(F)c1N1Cc2ncccc2C1)=O JDXHDLULUWEYIU-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14862199P | 1999-08-12 | 1999-08-12 | |
| US148621P | 1999-08-12 | ||
| PCT/US2000/021093 WO2001042242A1 (en) | 1999-08-12 | 2000-08-02 | Antibacterial heterobicyclic substituted phenyl oxazolidinones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60008545D1 DE60008545D1 (de) | 2004-04-01 |
| DE60008545T2 true DE60008545T2 (de) | 2004-12-23 |
Family
ID=22526580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60008545T Expired - Lifetime DE60008545T2 (de) | 1999-08-12 | 2000-08-02 | Antibakterielle heterobicyclisch substituierte phenyloxazolidinone |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US6413981B1 (https=) |
| EP (1) | EP1206469B1 (https=) |
| JP (1) | JP2003516404A (https=) |
| KR (1) | KR100463634B1 (https=) |
| CN (1) | CN1330647C (https=) |
| AR (1) | AR025225A1 (https=) |
| AT (1) | ATE260276T1 (https=) |
| AU (1) | AU783088B2 (https=) |
| BR (1) | BR0013237A (https=) |
| CA (1) | CA2378183C (https=) |
| CZ (1) | CZ2002882A3 (https=) |
| DE (1) | DE60008545T2 (https=) |
| DK (1) | DK1206469T3 (https=) |
| ES (1) | ES2215713T3 (https=) |
| HU (1) | HUP0202447A3 (https=) |
| IL (1) | IL147868A0 (https=) |
| MX (1) | MXPA02001559A (https=) |
| MY (1) | MY125359A (https=) |
| PL (1) | PL198558B1 (https=) |
| PT (1) | PT1206469E (https=) |
| RU (1) | RU2278117C2 (https=) |
| TW (1) | TW593313B (https=) |
| WO (1) | WO2001042242A1 (https=) |
Families Citing this family (86)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6608081B2 (en) * | 1999-08-12 | 2003-08-19 | Ortho-Mcneil Pharmaceutical, Inc. | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods |
| GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| DE19962924A1 (de) * | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| DE60118241T2 (de) * | 2000-10-17 | 2006-12-28 | Pharmacia & Upjohn Co. Llc, Kalamazoo | Verfahren zur herstellung von oxazolidinonverbindungen |
| DE10129725A1 (de) | 2001-06-20 | 2003-01-02 | Bayer Ag | Kombinationstherapie substituierter Oxazolidinone |
| WO2003093247A2 (en) * | 2002-04-30 | 2003-11-13 | Orchid Chemicals & Pharmaceuticals Ltd | Antibacterial agents |
| WO2003106454A1 (en) * | 2002-06-12 | 2003-12-24 | Orchid Chemicals & Pharmaceuticals Ltd | 1h-isoquinoline-oxazolidinone derivaties and their use as antibacterial agents |
| AU2002339721A1 (en) | 2002-09-20 | 2004-04-08 | Lupin Limited | Oxazolidinone derivatives, process for their preperation and their use as antimycobacterial agents |
| AR043050A1 (es) | 2002-09-26 | 2005-07-13 | Rib X Pharmaceuticals Inc | Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos |
| DE10355461A1 (de) | 2003-11-27 | 2005-06-23 | Bayer Healthcare Ag | Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung |
| KR100854211B1 (ko) | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물 |
| JP5383037B2 (ja) | 2004-02-27 | 2014-01-08 | リブ−エックス ファーマシューティカルズ，インコーポレイテッド | 大環状化合物およびそれらを製造し使用する方法 |
| EP1685841A1 (en) | 2005-01-31 | 2006-08-02 | Bayer Health Care Aktiengesellschaft | Prevention and treatment of thromboembolic disorders |
| EP3290427A1 (en) | 2005-08-24 | 2018-03-07 | Melinta Therapeutics, Inc. | Triazole compounds and methods of making and using the same |
| JP2009506063A (ja) | 2005-08-24 | 2009-02-12 | リブ−エックス ファーマシューティカルズ，インコーポレイテッド | トリアゾール化合物ならびにこれを作製する方法および使用する方法 |
| DE102005047561A1 (de) | 2005-10-04 | 2007-04-05 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung |
| US8188270B2 (en) | 2005-10-04 | 2012-05-29 | Bayer Schering Pharma Aktiengesellschaft | Polymorphous form of 5-chloro-N-({(5S)-2-oxo-3[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide |
| JP4012239B2 (ja) * | 2006-01-11 | 2007-11-21 | 生化学工業株式会社 | オキサゾロン誘導体 |
| US7776855B2 (en) * | 2006-07-27 | 2010-08-17 | Janssen Pharmaceutica N.V. | Antimicrobial oxazolidinone prodrugs |
| WO2008045473A1 (en) * | 2006-10-11 | 2008-04-17 | Transform Pharmaceuticals, Inc. | Novel crystal of n-[[(5s)-3-[4-(2,6-dihydro-2-methylpyrolo[3,4-c] pyrazol-5(4h)-yl)-3-fluoropheny]-2-oxo-5-oxazolidinyl]methyl] acetamide |
| US8124623B2 (en) | 2006-11-10 | 2012-02-28 | Actelion Pharmaceuticals Ltd. | 5-hydroxymethyl-oxazolidin-2-one-derivatives and their uses as antibacterials |
| RU2453546C2 (ru) * | 2006-11-10 | 2012-06-20 | Актелион Фармасьютиклз Лтд | Производные 5-гидроксиметилоксазолидин-2-она |
| CN101084901B (zh) * | 2007-06-22 | 2011-12-21 | 复旦大学 | 一种葡萄球菌抑制剂 |
| US8218847B2 (en) | 2008-06-06 | 2012-07-10 | Superdimension, Ltd. | Hybrid registration method |
| WO2010042887A2 (en) | 2008-10-10 | 2010-04-15 | Trius Therapeutics | Methods for preparing oxazolidinones and compositions containing them |
| KR101918678B1 (ko) | 2009-02-03 | 2018-11-14 | 머크 샤프 앤드 돔 코포레이션 | Ｒ)-3-(4-(2-(2-메틸테트라졸-5-일)피리딘-5-일)-3-플루오로페닐)-5-히드록시메틸 옥사졸리딘-2-온 디히드로겐 포스페이트의 결정형 |
| CN103030634B (zh) * | 2011-09-30 | 2015-07-15 | 山东轩竹医药科技有限公司 | 含有并环的噁唑烷酮类抗菌素 |
| JP6162704B2 (ja) * | 2011-10-11 | 2017-07-12 | カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ | オキサゾリジノン誘導体のシラアナログ及びその合成 |
| US9603668B2 (en) | 2014-07-02 | 2017-03-28 | Covidien Lp | Dynamic 3D lung map view for tool navigation inside the lung |
| US9633431B2 (en) | 2014-07-02 | 2017-04-25 | Covidien Lp | Fluoroscopic pose estimation |
| US9986983B2 (en) | 2014-10-31 | 2018-06-05 | Covidien Lp | Computed tomography enhanced fluoroscopic system, device, and method of utilizing the same |
| HK1244211A1 (zh) | 2014-11-14 | 2018-08-03 | Melinta Therapeutics, Inc. | 治疗、预防或降低皮肤感染风险的方法 |
| US10702527B2 (en) | 2015-06-12 | 2020-07-07 | Dana-Farber Cancer Institute, Inc. | Combination therapy of transcription inhibitors and kinase inhibitors |
| US10674982B2 (en) | 2015-08-06 | 2020-06-09 | Covidien Lp | System and method for local three dimensional volume reconstruction using a standard fluoroscope |
| US10702226B2 (en) | 2015-08-06 | 2020-07-07 | Covidien Lp | System and method for local three dimensional volume reconstruction using a standard fluoroscope |
| US10716525B2 (en) | 2015-08-06 | 2020-07-21 | Covidien Lp | System and method for navigating to target and performing procedure on target utilizing fluoroscopic-based local three dimensional volume reconstruction |
| US10575754B2 (en) | 2015-09-23 | 2020-03-03 | Covidien Lp | Catheter having a sensor and an extended working channel |
| MX2018006499A (es) | 2015-11-25 | 2018-08-01 | Dana Farber Cancer Inst Inc | Inhibidores de bromodominio bivalentes y usos de los mismos. |
| US20190246638A1 (en) * | 2016-02-16 | 2019-08-15 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd, | Non-protein phenylalanine analogues for inhibiting cyanobacteria and plant growth |
| WO2018001944A1 (en) | 2016-06-29 | 2018-01-04 | F. Hoffmann-La Roche Ag | Novel dihydropyrrolopyrimidines for the treatment and prophylaxis of hepatitis b virus infection |
| US10087171B2 (en) | 2016-12-19 | 2018-10-02 | Actelion Pharmaceuticals Ltd | Crystalline forms of cadazolid |
| US11529190B2 (en) | 2017-01-30 | 2022-12-20 | Covidien Lp | Enhanced ablation and visualization techniques for percutaneous surgical procedures |
| US11793579B2 (en) | 2017-02-22 | 2023-10-24 | Covidien Lp | Integration of multiple data sources for localization and navigation |
| US10699448B2 (en) | 2017-06-29 | 2020-06-30 | Covidien Lp | System and method for identifying, marking and navigating to a target using real time two dimensional fluoroscopic data |
| WO2019075074A1 (en) | 2017-10-10 | 2019-04-18 | Covidien Lp | SYSTEM AND METHOD FOR IDENTIFICATION AND MARKING OF A TARGET IN A THREE-DIMENSIONAL FLUOROSCOPIC RECONSTRUCTION |
| US10930064B2 (en) | 2018-02-08 | 2021-02-23 | Covidien Lp | Imaging reconstruction system and method |
| US11364004B2 (en) | 2018-02-08 | 2022-06-21 | Covidien Lp | System and method for pose estimation of an imaging device and for determining the location of a medical device with respect to a target |
| US10905498B2 (en) | 2018-02-08 | 2021-02-02 | Covidien Lp | System and method for catheter detection in fluoroscopic images and updating displayed position of catheter |
| US10872449B2 (en) | 2018-05-02 | 2020-12-22 | Covidien Lp | System and method for constructing virtual radial ultrasound images from CT data and performing a surgical navigation procedure using virtual ultrasound images |
| US12109203B2 (en) | 2018-07-25 | 2024-10-08 | Zydus Lifesciences Limited | Substituted oxazolidinones for the treatment of mammalian infections |
| US11705238B2 (en) | 2018-07-26 | 2023-07-18 | Covidien Lp | Systems and methods for providing assistance during surgery |
| US11071591B2 (en) | 2018-07-26 | 2021-07-27 | Covidien Lp | Modeling a collapsed lung using CT data |
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| US11617493B2 (en) | 2018-12-13 | 2023-04-04 | Covidien Lp | Thoracic imaging, distance measuring, surgical awareness, and notification system and method |
| US11801113B2 (en) | 2018-12-13 | 2023-10-31 | Covidien Lp | Thoracic imaging, distance measuring, and notification system and method |
| US11357593B2 (en) | 2019-01-10 | 2022-06-14 | Covidien Lp | Endoscopic imaging with augmented parallax |
| US11625825B2 (en) | 2019-01-30 | 2023-04-11 | Covidien Lp | Method for displaying tumor location within endoscopic images |
| US11564751B2 (en) | 2019-02-01 | 2023-01-31 | Covidien Lp | Systems and methods for visualizing navigation of medical devices relative to targets |
| US11925333B2 (en) | 2019-02-01 | 2024-03-12 | Covidien Lp | System for fluoroscopic tracking of a catheter to update the relative position of a target and the catheter in a 3D model of a luminal network |
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| US11975157B2 (en) | 2019-04-12 | 2024-05-07 | Covidien Lp | Method of manufacturing an elongated catheter having multiple sensors for three-dimensional location of the catheter |
| WO2020234636A1 (en) | 2019-05-17 | 2020-11-26 | Cadila Healthcare Limited | Novel compounds for the treatment of mammalian infections |
| US12089902B2 (en) | 2019-07-30 | 2024-09-17 | Coviden Lp | Cone beam and 3D fluoroscope lung navigation |
| US11269173B2 (en) | 2019-08-19 | 2022-03-08 | Covidien Lp | Systems and methods for displaying medical video images and/or medical 3D models |
| US12059281B2 (en) | 2019-08-19 | 2024-08-13 | Covidien Lp | Systems and methods of fluoro-CT imaging for initial registration |
| US11864935B2 (en) | 2019-09-09 | 2024-01-09 | Covidien Lp | Systems and methods for pose estimation of a fluoroscopic imaging device and for three-dimensional imaging of body structures |
| US11931111B2 (en) | 2019-09-09 | 2024-03-19 | Covidien Lp | Systems and methods for providing surgical guidance |
| US11627924B2 (en) | 2019-09-24 | 2023-04-18 | Covidien Lp | Systems and methods for image-guided navigation of percutaneously-inserted devices |
| US12102298B2 (en) | 2019-12-10 | 2024-10-01 | Covidien Lp | Lymphatic system tracking |
| US11847730B2 (en) | 2020-01-24 | 2023-12-19 | Covidien Lp | Orientation detection in fluoroscopic images |
| US11380060B2 (en) | 2020-01-24 | 2022-07-05 | Covidien Lp | System and method for linking a segmentation graph to volumetric data |
| US11922581B2 (en) | 2020-05-08 | 2024-03-05 | Coviden Lp | Systems and methods of controlling an operating room display using an augmented reality headset |
| US12064191B2 (en) | 2020-06-03 | 2024-08-20 | Covidien Lp | Surgical tool navigation using sensor fusion |
| US11701492B2 (en) | 2020-06-04 | 2023-07-18 | Covidien Lp | Active distal tip drive |
| US12008760B2 (en) | 2020-07-24 | 2024-06-11 | Covidien Lp | Systems and methods for estimating the movement of a target using a universal deformation model for anatomic tissue |
| US11950950B2 (en) | 2020-07-24 | 2024-04-09 | Covidien Lp | Zoom detection and fluoroscope movement detection for target overlay |
| US12256923B2 (en) | 2020-08-13 | 2025-03-25 | Covidien Lp | Endoluminal robotic systems and methods for suturing |
| US12383352B2 (en) | 2020-08-13 | 2025-08-12 | Covidien Lp | Endoluminal robotic (ELR) systems and methods |
| US12161309B2 (en) | 2020-09-24 | 2024-12-10 | Covidien Lp | Articulating mechanism for the laparoscopic ablation device for blunt dissection |
| US12303220B2 (en) | 2022-01-26 | 2025-05-20 | Covidien Lp | Autonomous endobronchial access with an EM guided catheter |
| US12558164B2 (en) | 2022-05-27 | 2026-02-24 | Covidien Lp | Creating a navigation pathway to a target in the lung and method of navigating to the target |
| US12257082B2 (en) | 2022-06-30 | 2025-03-25 | Covidien Lp | Cone beam computed tomography integration for creating a navigation pathway to a target in the lung and method of navigating to the target |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE146783T1 (de) | 1991-11-01 | 1997-01-15 | Upjohn Co | Substituierte aryl- und heteroaryl- phenyloxazolidinone |
| SK283420B6 (sk) * | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
| MY115155A (en) | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
| BR9509673A (pt) | 1994-11-15 | 1997-09-30 | Upjohn Co | Compostos e uso dos mesmos |
| DK0807112T3 (da) | 1995-02-03 | 2001-12-17 | Upjohn Co | Antimikrobiel heteroaromatisk ringsubstitueret phenyloxazolidinon |
| US6124334A (en) | 1995-02-03 | 2000-09-26 | Pharmacia & Upjohn Company | Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials |
| NZ306310A (en) | 1995-05-11 | 2001-05-25 | Upjohn Co | Spirocyclic and bicyclic diazinyl and carbazinyl oxazolidinones |
| US5883093A (en) | 1995-09-12 | 1999-03-16 | Pharmacia & Upjohn Company | Phenyloxazolidinone antimicrobials |
| DE19601264A1 (de) | 1996-01-16 | 1997-07-17 | Bayer Ag | Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone |
| DE19604223A1 (de) | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue substituierte Oxazolidinone |
| ES2166073T3 (es) | 1996-04-11 | 2002-04-01 | Upjohn Co | Procedimiento para preparar oxazolidinonas. |
| CN1138765C (zh) | 1997-05-30 | 2004-02-18 | 法玛西雅厄普约翰美国公司 | 带有硫代羰基功能基的噁唑烷酮抗菌剂 |
| GB9717807D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
| DE19736973A1 (de) * | 1997-08-25 | 1999-03-04 | Basf Ag | Formmassen auf der Basis von Polyarylenethern und Polyamiden |
| JPH11322729A (ja) | 1998-03-09 | 1999-11-24 | Hokuriku Seiyaku Co Ltd | ジチオカルバミド酸誘導体 |
-
2000
- 2000-07-21 US US09/621,814 patent/US6413981B1/en not_active Expired - Lifetime
- 2000-08-02 CA CA002378183A patent/CA2378183C/en not_active Expired - Lifetime
- 2000-08-02 BR BR0013237-3A patent/BR0013237A/pt not_active Application Discontinuation
- 2000-08-02 ES ES00957285T patent/ES2215713T3/es not_active Expired - Lifetime
- 2000-08-02 WO PCT/US2000/021093 patent/WO2001042242A1/en not_active Ceased
- 2000-08-02 JP JP2001543541A patent/JP2003516404A/ja active Pending
- 2000-08-02 DK DK00957285T patent/DK1206469T3/da active
- 2000-08-02 AU AU68928/00A patent/AU783088B2/en not_active Ceased
- 2000-08-02 HU HU0202447A patent/HUP0202447A3/hu unknown
- 2000-08-02 AT AT00957285T patent/ATE260276T1/de active
- 2000-08-02 MX MXPA02001559A patent/MXPA02001559A/es active IP Right Grant
- 2000-08-02 KR KR10-2002-7001679A patent/KR100463634B1/ko not_active Expired - Fee Related
- 2000-08-02 RU RU2002103379/04A patent/RU2278117C2/ru not_active IP Right Cessation
- 2000-08-02 IL IL14786800A patent/IL147868A0/xx unknown
- 2000-08-02 EP EP00957285A patent/EP1206469B1/en not_active Expired - Lifetime
- 2000-08-02 CZ CZ2002882A patent/CZ2002882A3/cs unknown
- 2000-08-02 PL PL354200A patent/PL198558B1/pl not_active IP Right Cessation
- 2000-08-02 DE DE60008545T patent/DE60008545T2/de not_active Expired - Lifetime
- 2000-08-02 CN CNB008178763A patent/CN1330647C/zh not_active Expired - Fee Related
- 2000-08-02 PT PT00957285T patent/PT1206469E/pt unknown
- 2000-08-10 MY MYPI20003657 patent/MY125359A/en unknown
- 2000-08-11 AR ARP000104161A patent/AR025225A1/es not_active Application Discontinuation
- 2000-09-18 TW TW089116145A patent/TW593313B/zh not_active IP Right Cessation
-
2002
- 2002-01-10 US US10/043,747 patent/US20030171366A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR100463634B1 (ko) | 2004-12-30 |
| PL198558B1 (pl) | 2008-06-30 |
| ES2215713T3 (es) | 2004-10-16 |
| PL354200A1 (en) | 2003-12-29 |
| KR20020016652A (ko) | 2002-03-04 |
| DK1206469T3 (da) | 2004-05-10 |
| US20030171366A1 (en) | 2003-09-11 |
| MY125359A (en) | 2006-07-31 |
| HUP0202447A2 (en) | 2002-10-28 |
| AU783088B2 (en) | 2005-09-22 |
| WO2001042242A1 (en) | 2001-06-14 |
| CZ2002882A3 (cs) | 2002-06-12 |
| IL147868A0 (en) | 2002-08-14 |
| AU6892800A (en) | 2001-06-18 |
| DE60008545D1 (de) | 2004-04-01 |
| EP1206469B1 (en) | 2004-02-25 |
| CN1414964A (zh) | 2003-04-30 |
| US6413981B1 (en) | 2002-07-02 |
| ATE260276T1 (de) | 2004-03-15 |
| RU2278117C2 (ru) | 2006-06-20 |
| HUP0202447A3 (en) | 2003-10-28 |
| CN1330647C (zh) | 2007-08-08 |
| AR025225A1 (es) | 2002-11-13 |
| BR0013237A (pt) | 2003-07-15 |
| CA2378183A1 (en) | 2001-06-14 |
| EP1206469A1 (en) | 2002-05-22 |
| MXPA02001559A (es) | 2003-10-14 |
| RU2002103379A (ru) | 2003-09-20 |
| JP2003516404A (ja) | 2003-05-13 |
| PT1206469E (pt) | 2004-06-30 |
| CA2378183C (en) | 2009-10-20 |
| TW593313B (en) | 2004-06-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN |