DE4445224B4 - Benzolderivate - Google Patents

Benzolderivate Download PDF

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Publication number
DE4445224B4
DE4445224B4 DE4445224.1A DE4445224A DE4445224B4 DE 4445224 B4 DE4445224 B4 DE 4445224B4 DE 4445224 A DE4445224 A DE 4445224A DE 4445224 B4 DE4445224 B4 DE 4445224B4
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DE
Germany
Prior art keywords
compounds
phe
radical
formula
mol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE4445224.1A
Other languages
German (de)
English (en)
Other versions
DE4445224A1 (de
Inventor
Volker Reiffenrath
Dr. Plach Herbert
Dr. Hittich Reinhard
Dr. Poetsch Eike
Dr. Rieger Bernhard
Dr. Bartmann Ekkehard
Dr. Pauluth Detlef
Dr. Schoen Sabine
Dr. Tarumi Kazuaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Priority to DE4445224.1A priority Critical patent/DE4445224B4/de
Priority to JP04770795A priority patent/JP4006030B2/ja
Publication of DE4445224A1 publication Critical patent/DE4445224A1/de
Priority to JP2006253471A priority patent/JP4472676B2/ja
Priority to JP2007188370A priority patent/JP4472734B2/ja
Application granted granted Critical
Publication of DE4445224B4 publication Critical patent/DE4445224B4/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
    • C09K19/06—Non-steroidal liquid crystal compounds
    • C09K19/08—Non-steroidal liquid crystal compounds containing at least two non-condensed rings
    • C09K19/30—Non-steroidal liquid crystal compounds containing at least two non-condensed rings containing saturated or unsaturated non-aromatic rings, e.g. cyclohexane rings
    • C09K19/3098—Unsaturated non-aromatic rings, e.g. cyclohexene rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/18—Preparation of halogenated hydrocarbons by replacement by halogens of oxygen atoms of carbonyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C23/00—Compounds containing at least one halogen atom bound to a ring other than a six-membered aromatic ring
    • C07C23/18—Polycyclic halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C25/00—Compounds containing at least one halogen atom bound to a six-membered aromatic ring
    • C07C25/18—Polycyclic aromatic halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/50—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
    • C09K19/0403—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit the structure containing one or more specific, optionally substituted ring or ring systems
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
    • C09K19/06—Non-steroidal liquid crystal compounds
    • C09K19/08—Non-steroidal liquid crystal compounds containing at least two non-condensed rings
    • C09K19/30—Non-steroidal liquid crystal compounds containing at least two non-condensed rings containing saturated or unsaturated non-aromatic rings, e.g. cyclohexane rings
    • C09K19/3001—Cyclohexane rings
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
    • C09K19/06—Non-steroidal liquid crystal compounds
    • C09K19/08—Non-steroidal liquid crystal compounds containing at least two non-condensed rings
    • C09K19/30—Non-steroidal liquid crystal compounds containing at least two non-condensed rings containing saturated or unsaturated non-aromatic rings, e.g. cyclohexane rings
    • C09K19/3001—Cyclohexane rings
    • C09K19/3003—Compounds containing at least two rings in which the different rings are directly linked (covalent bond)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
    • C09K19/0403—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit the structure containing one or more specific, optionally substituted ring or ring systems
    • C09K2019/0407—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit the structure containing one or more specific, optionally substituted ring or ring systems containing a carbocyclic ring, e.g. dicyano-benzene, chlorofluoro-benzene or cyclohexanone
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
    • C09K2019/0444—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit characterized by a linking chain between rings or ring systems, a bridging chain between extensive mesogenic moieties or an end chain group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Liquid Crystal Substances (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Liquid Crystal (AREA)
DE4445224.1A 1994-12-17 1994-12-17 Benzolderivate Expired - Lifetime DE4445224B4 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DE4445224.1A DE4445224B4 (de) 1994-12-17 1994-12-17 Benzolderivate
JP04770795A JP4006030B2 (ja) 1994-12-17 1995-01-31 ベンゼン誘導体
JP2006253471A JP4472676B2 (ja) 1994-12-17 2006-09-19 ベンゼン誘導体
JP2007188370A JP4472734B2 (ja) 1994-12-17 2007-07-19 ベンゼン誘導体

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4445224.1A DE4445224B4 (de) 1994-12-17 1994-12-17 Benzolderivate

Publications (2)

Publication Number Publication Date
DE4445224A1 DE4445224A1 (de) 1996-06-20
DE4445224B4 true DE4445224B4 (de) 2014-03-27

Family

ID=6536223

Family Applications (1)

Application Number Title Priority Date Filing Date
DE4445224.1A Expired - Lifetime DE4445224B4 (de) 1994-12-17 1994-12-17 Benzolderivate

Country Status (2)

Country Link
JP (3) JP4006030B2 (ja)
DE (1) DE4445224B4 (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8802064B2 (en) 2009-04-07 2014-08-12 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
US8802119B2 (en) 2009-04-07 2014-08-12 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
US8957049B2 (en) 2008-04-09 2015-02-17 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
US9034849B2 (en) 2010-02-03 2015-05-19 Infinity Pharmaceuticals, Inc. Fatty acid amide hydrolase inhibitors
US9108989B2 (en) 2006-10-10 2015-08-18 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011607A (en) 1995-02-15 2000-01-04 Semiconductor Energy Laboratory Co., Active matrix display with sealing material
GB2310428B (en) * 1996-02-20 2000-03-29 Merck Patent Gmbh Mixture of non-cyano high birefringence laterally fluorinated terphenyl & cyclohexyl-biphenyl liquid crystalline compounds having halogenated terminal groups
DE69909436T2 (de) * 1999-05-19 2004-04-15 Merck Patent Gmbh Isothioncyanat-Tolane und sie enthaltende flüssigkristalline Gemische
JP5279975B2 (ja) * 2000-12-19 2013-09-04 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 負のｄｃ異方性のアルケニル化合物と液晶性媒体
DE102004036068B4 (de) * 2003-08-18 2023-05-17 Merck Patent Gmbh Verfahren zur Hydrierung
WO2005123878A1 (de) 2004-06-18 2005-12-29 Merck Patent Gmbh Flüssigkristallines medium
WO2005123879A1 (de) 2004-06-18 2005-12-29 Merck Patent Gmbh Flüssigkristallines medium
EP1956069B1 (de) * 2007-02-02 2011-03-30 Merck Patent GmbH Flüssigkristallines Medium
JP6098632B2 (ja) * 2012-02-23 2017-03-22 Jnc株式会社 テトラフルオロプロペニルを有する液晶性化合物、液晶組成物、および液晶表示素子
US9273245B2 (en) * 2012-07-26 2016-03-01 Jnc Corporation Compound having 2,2-difluorovinyloxy group or 1,2,2-trifluorovinyloxy group, liquid crystal composition and liquid crystal display device
JP6953120B2 (ja) * 2015-08-05 2021-10-27 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ 液晶媒体
CN106010580B (zh) * 2016-05-25 2018-08-28 石家庄诚志永华显示材料有限公司 液晶组合物及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4107120A1 (de) * 1990-03-13 1991-09-19 Merck Patent Gmbh 4,4'disubstituierte 2',3-difluorphenyle und fluessigkristallines medium
JPH05310616A (ja) * 1992-05-15 1993-11-22 Dainippon Ink & Chem Inc フルオロシクロヘキセン誘導体

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0310945Y2 (ja) * 1985-02-26 1991-03-18
GB8814327D0 (en) * 1988-06-16 1988-07-20 Secr Defence Fluorinated 4"-cyano substituted terphenyls
WO1990009420A1 (en) * 1989-02-17 1990-08-23 MERCK Patent Gesellschaft mit beschränkter Haftung Liquid crystalline media containing fluorinated oligophenyls
DE59010895D1 (de) * 1989-09-06 2000-02-24 Merck Patent Gmbh Fluorbenzolderivate und flüssigkristallines Medium
EP0449015B1 (de) * 1990-03-24 1998-07-01 MERCK PATENT GmbH Difluormethylverbindungen und flüssigkristallines Medium
DE4142519B4 (de) * 1991-01-31 2005-06-02 Merck Patent Gmbh Fluorbenzolderivate
DE4217248B4 (de) * 1991-06-05 2005-06-16 Merck Patent Gmbh Vinylverbindungen
JPH0525068A (ja) * 1991-07-17 1993-02-02 Seiko Epson Corp ターフエニル誘導体及びそれを含有する液晶組成物及びそれを用いた液晶表示素子
WO1993003113A1 (de) * 1991-08-03 1993-02-18 MERCK Patent Gesellschaft mit beschränkter Haftung Flüssigkristalline verbindungen
JPH0558981A (ja) * 1991-08-27 1993-03-09 Seiko Epson Corp ターフエニル誘導体及びそれを含有する液晶組成物及びそれを用いた液晶表示素子
DE4215277B4 (de) * 1992-05-09 2006-06-08 Merck Patent Gmbh Benzolderivate und ihre Verwendung für ein flüssigkristallines Medium
JP3601069B2 (ja) * 1993-02-15 2004-12-15 セイコーエプソン株式会社 ターフェニルメタクリレート誘導体
DE4308028B4 (de) * 1993-03-13 2012-08-16 Merck Patent Gmbh 1,2,2,2-Tetrafluorethylether und flüssigkristallines Medium
DE4314085A1 (de) * 1993-04-29 1994-11-03 Merck Patent Gmbh Benzolderivate und flüssigkristallines Medium
US5422035A (en) * 1993-05-10 1995-06-06 Merck Patent Gesellschaft Mit Beschrankter Haftung Benzene derivatives, and liquid-crystalline medium
US5744058A (en) * 1994-06-03 1998-04-28 Merck Patent Gesellschaft Mit Beschrankter Haftung Dienes and liquid-crystalline media
JP3698174B2 (ja) * 1994-07-15 2005-09-21 セイコーエプソン株式会社 液晶組成物およびこれを用いた液晶表示素子

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4107120A1 (de) * 1990-03-13 1991-09-19 Merck Patent Gmbh 4,4'disubstituierte 2',3-difluorphenyle und fluessigkristallines medium
JPH05310616A (ja) * 1992-05-15 1993-11-22 Dainippon Ink & Chem Inc フルオロシクロヘキセン誘導体

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9108989B2 (en) 2006-10-10 2015-08-18 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
US8957049B2 (en) 2008-04-09 2015-02-17 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
US8802064B2 (en) 2009-04-07 2014-08-12 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
US8802119B2 (en) 2009-04-07 2014-08-12 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
US9034849B2 (en) 2010-02-03 2015-05-19 Infinity Pharmaceuticals, Inc. Fatty acid amide hydrolase inhibitors

Also Published As

Publication number Publication date
JP4006030B2 (ja) 2007-11-14
JP4472734B2 (ja) 2010-06-02
JP4472676B2 (ja) 2010-06-02
JP2007320962A (ja) 2007-12-13
JPH08176033A (ja) 1996-07-09
DE4445224A1 (de) 1996-06-20
JP2007045833A (ja) 2007-02-22

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