DE4035809A1 - Verwendung von thiazoloisoindolinon-derivaten als antivirale arzneimittel - Google Patents

Verwendung von thiazoloisoindolinon-derivaten als antivirale arzneimittel

Info

Publication number
DE4035809A1
DE4035809A1 DE4035809A DE4035809A DE4035809A1 DE 4035809 A1 DE4035809 A1 DE 4035809A1 DE 4035809 A DE4035809 A DE 4035809A DE 4035809 A DE4035809 A DE 4035809A DE 4035809 A1 DE4035809 A1 DE 4035809A1
Authority
DE
Germany
Prior art keywords
dihydrothiazolo
isoindol
compounds
phenyl
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE4035809A
Other languages
German (de)
English (en)
Inventor
Harald Dipl Chem Dr Rer Zilch
Alfred Dr Rer Nat Mertens
Herbert Dr Ing Leinert
Ulrike Dipl Biol Dr Leser
Bernhard Dipl Biol Dr R Koenig
Hans Dr Rer Nat Seidel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE4035809A priority Critical patent/DE4035809A1/de
Priority to TW080108378A priority patent/TW198680B/zh
Priority to US08/050,067 priority patent/US5397794A/en
Priority to JP3517357A priority patent/JPH06501690A/ja
Priority to AU88650/91A priority patent/AU8865091A/en
Priority to DE59104441T priority patent/DE59104441D1/de
Priority to MX9101948A priority patent/MX9101948A/es
Priority to ES91919525T priority patent/ES2069313T3/es
Priority to AT91919525T priority patent/ATE117552T1/de
Priority to CA002095249A priority patent/CA2095249A1/en
Priority to EP91919525A priority patent/EP0556245B1/de
Priority to PCT/EP1991/002101 priority patent/WO1992008457A1/de
Priority to IL99989A priority patent/IL99989A0/xx
Priority to IE389891A priority patent/IE913898A1/en
Priority to PT99463A priority patent/PT99463A/pt
Priority to ZA918862A priority patent/ZA918862B/xx
Priority to CN91110726A priority patent/CN1061341A/zh
Publication of DE4035809A1 publication Critical patent/DE4035809A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE4035809A 1990-11-10 1990-11-10 Verwendung von thiazoloisoindolinon-derivaten als antivirale arzneimittel Withdrawn DE4035809A1 (de)

Priority Applications (17)

Application Number Priority Date Filing Date Title
DE4035809A DE4035809A1 (de) 1990-11-10 1990-11-10 Verwendung von thiazoloisoindolinon-derivaten als antivirale arzneimittel
TW080108378A TW198680B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1990-11-10 1991-10-23
US08/050,067 US5397794A (en) 1990-11-10 1991-11-06 Use of thiazoloisoindolinone derivatives as antiviral medicaments
JP3517357A JPH06501690A (ja) 1990-11-10 1991-11-06 抗ウイルス薬としてのチアゾロイソインドリノン誘導体の使用
AU88650/91A AU8865091A (en) 1990-11-10 1991-11-06 Use of thiazolo-isoindolinone derivatives as antiviral medicaments
DE59104441T DE59104441D1 (de) 1990-11-10 1991-11-06 Verwendung von thiazoloisoindolinon-derivaten als antivirale arzneimittel.
MX9101948A MX9101948A (es) 1990-11-10 1991-11-06 Composicion farmaceutica que contiene derivados de tiazoloisoindolinona
ES91919525T ES2069313T3 (es) 1990-11-10 1991-11-06 Utilizacion de derivados de tiazoloisoindolinona como medicamentos antiviricos.
AT91919525T ATE117552T1 (de) 1990-11-10 1991-11-06 Verwendung von thiazoloisoindolinon-derivaten als antivirale arzneimittel.
CA002095249A CA2095249A1 (en) 1990-11-10 1991-11-06 Use of thiazoloisoindolinone derivatives as antiviral medicaments
EP91919525A EP0556245B1 (de) 1990-11-10 1991-11-06 Verwendung von thiazoloisoindolinon-derivaten als antivirale arzneimittel
PCT/EP1991/002101 WO1992008457A1 (de) 1990-11-10 1991-11-06 Verwendung von thiazoloisoindolinon-derivaten als antivirale arzneimittel
IL99989A IL99989A0 (en) 1990-11-10 1991-11-07 Anti-viral pharmaceutical compositions containing thiazoloisoindolinone derivatives
IE389891A IE913898A1 (en) 1990-11-10 1991-11-08 The use of thiazoloisoindolinone derivatives as antiviral¹medicaments
PT99463A PT99463A (pt) 1990-11-10 1991-11-08 Processo para a preparacao de composicoes farmaceuticas contendo derivados de triazoloisoindolinona
ZA918862A ZA918862B (en) 1990-11-10 1991-11-08 The use of thiazoloisoindolinone derivatives as antriviral medicaments
CN91110726A CN1061341A (zh) 1990-11-10 1991-11-09 用作抗病毒药物的噻唑并异二氢氮杂茚酮衍生物)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4035809A DE4035809A1 (de) 1990-11-10 1990-11-10 Verwendung von thiazoloisoindolinon-derivaten als antivirale arzneimittel

Publications (1)

Publication Number Publication Date
DE4035809A1 true DE4035809A1 (de) 1992-05-14

Family

ID=6418011

Family Applications (2)

Application Number Title Priority Date Filing Date
DE4035809A Withdrawn DE4035809A1 (de) 1990-11-10 1990-11-10 Verwendung von thiazoloisoindolinon-derivaten als antivirale arzneimittel
DE59104441T Expired - Fee Related DE59104441D1 (de) 1990-11-10 1991-11-06 Verwendung von thiazoloisoindolinon-derivaten als antivirale arzneimittel.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE59104441T Expired - Fee Related DE59104441D1 (de) 1990-11-10 1991-11-06 Verwendung von thiazoloisoindolinon-derivaten als antivirale arzneimittel.

Country Status (16)

Country Link
US (1) US5397794A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0556245B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH06501690A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1061341A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE117552T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU8865091A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2095249A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE4035809A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2069313T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE913898A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL99989A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX9101948A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT99463A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW198680B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1992008457A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA918862B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4129779A1 (de) * 1991-09-07 1993-03-11 Boehringer Mannheim Gmbh Neue tricyclische thiazol- und oxazol-derivate und diese enthaltende arzneimittel
US6241762B1 (en) 1998-03-30 2001-06-05 Conor Medsystems, Inc. Expandable medical device with ductile hinges
US7208010B2 (en) 2000-10-16 2007-04-24 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
US20040254635A1 (en) 1998-03-30 2004-12-16 Shanley John F. Expandable medical device for delivery of beneficial agent
DE20122506U1 (de) 2000-10-16 2005-12-08 Conor Medsystems, Inc., Menlo Park Ausdehnbare medizinische Vorrichtung zur Abgabe eines nützlichen Agens
US7785653B2 (en) 2003-09-22 2010-08-31 Innovational Holdings Llc Method and apparatus for loading a beneficial agent into an expandable medical device
KR101630243B1 (ko) * 2012-12-14 2016-06-15 한국화학연구원 신규한 화합물, 이의 약학적으로 허용가능한 염 또는 이의 광학 이성질체, 이의 제조방법 및 이를 유효성분으로 함유하는 바이러스성 질환의 예방 또는 치료용 약학적 조성물
CN116283657B (zh) * 2023-02-22 2024-08-20 贵州大学 一种茚酮衍生物及其合成方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3334113A (en) * 1963-12-18 1967-08-01 Sandoz Ag 9b-phenyl-1, 2, 3, 9b-tetrahydro-5h-imidazo[2,1-a]isoindol-5-ones

Also Published As

Publication number Publication date
CN1061341A (zh) 1992-05-27
ATE117552T1 (de) 1995-02-15
EP0556245A1 (de) 1993-08-25
US5397794A (en) 1995-03-14
ZA918862B (en) 1992-08-26
IE913898A1 (en) 1992-05-20
IL99989A0 (en) 1992-08-18
CA2095249A1 (en) 1992-05-11
MX9101948A (es) 1992-07-08
TW198680B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-01-21
EP0556245B1 (de) 1995-01-25
JPH06501690A (ja) 1994-02-24
ES2069313T3 (es) 1995-05-01
DE59104441D1 (de) 1995-03-09
PT99463A (pt) 1992-09-30
WO1992008457A1 (de) 1992-05-29
AU8865091A (en) 1992-06-11

Similar Documents

Publication Publication Date Title
DE3687069T2 (de) Verwendung von 3'-azido-3'-deoxythymidin zur behandlung oder vorbeugung von menschlichen retrovirus-infektionen.
WO1993016091A1 (de) Neue liponucleotide, deren herstellung sowie deren verwendung als antivirale arzneimittel
DE69313872T2 (de) Verbindung von nucleocidanaloga zur behandlung viraler infektionen
DE3850335T2 (de) Antiretroviraler Castanosperminester.
DE4035809A1 (de) Verwendung von thiazoloisoindolinon-derivaten als antivirale arzneimittel
DE4122240A1 (de) Dibenz(b,e)azepinderivate und diese enthaltende arzneimittel
DE3780814T2 (de) Verwendung von nukleosiden zur herstellung eines medikamentes zur behandlung von krankheiten, die durch einen retrovirus oder den hepatitis-b-virus verursacht werden.
EP0569457B1 (de) Verwendung von thiazolo-[2,3-a]isoindol-derivaten als antivirale arzneimittel und neue thiazolo- [2,3-a]isoindol-derivate
DE4129779A1 (de) Neue tricyclische thiazol- und oxazol-derivate und diese enthaltende arzneimittel
EP0557336B1 (de) Verwendung von 2h-1,2,4-benzothiadiazin-3(4h)-thion-1,1-dioxiden als antivirale arzneimittel
EP0559815B1 (de) Optisch aktive thiazoloisoindolinon-derivate mit antiviraler wirkung
DE4014672A1 (de) Verwendung von adamantan-derivaten zur zytoprotektion von nicht-infizierten und virus-infizierten lymphozyten als auch anderen zelltypen
DE4122418A1 (de) Optisch aktive thiazoloisoindolinon-derivate mit antiviraler wirkung
DE3724951A1 (de) Arzneimittel, enthaltend modifizierte desoxyribonukleinsaeure und dessen verwendung
DE4037674A1 (de) Optisch aktive thiazoloisoindolinon-derivate mit antiviraler wirkung
DE4320597A1 (de) Verwendung von Polyphosphaten zur antiviralen Therapie und als Immunmodulatoren
DE4003054A1 (de) Verwendung von benzylphosphonsaeurederivaten zur behandlung von durch viren verursachte krankheiten
DE3900964A1 (de) Neue nukleoside, verfahren zu deren herstellung sowie arzneimittel, die diese verbindungen enthalten
EP0643964A2 (en) Use of local anesthetics for the manufacture of a medicament for the protection of plasma cell membranes
EP1513539B1 (de) Verwendung von amphiphilen nucleosid-phosphonoameisensäure-derivaten zur behandlung von viralen infektionskrankheiten
EP0711275B1 (de) (thio)carbamidinsäure-derivate und diese enthaltende arzneimittel
EP0643712B1 (de) Spiro-oxetane, verfahren zu ihrer herstellung und arzneimittel
AT392794B (de) Verfahren zur herstellung von neuen pharmazeutisch annehmbaren estern und salzen von 3'-azido-3'-desoxythymidin
DE4117358A1 (de) Verwendung von tricyclischen isoindolinonen als antivirale arzneimittel, sowie neue optisch aktive isoindolinone
DE3623681A1 (de) Arzneimittel, verfahren zu ihrer herstellung und behandlungsverfahren

Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee