DE3780814T2 - Verwendung von nukleosiden zur herstellung eines medikamentes zur behandlung von krankheiten, die durch einen retrovirus oder den hepatitis-b-virus verursacht werden. - Google Patents

Verwendung von nukleosiden zur herstellung eines medikamentes zur behandlung von krankheiten, die durch einen retrovirus oder den hepatitis-b-virus verursacht werden.

Info

Publication number
DE3780814T2
DE3780814T2 DE8888900484T DE3780814T DE3780814T2 DE 3780814 T2 DE3780814 T2 DE 3780814T2 DE 8888900484 T DE8888900484 T DE 8888900484T DE 3780814 T DE3780814 T DE 3780814T DE 3780814 T2 DE3780814 T2 DE 3780814T2
Authority
DE
Germany
Prior art keywords
carbon atoms
retrovirus
hepatitis
virus
nucleosides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888900484T
Other languages
English (en)
Other versions
DE3780814D1 (de
Inventor
Roelf Datema
Birgitta Gotthammar
Nils Johansson
Maria Kovacs
Gunnar Lindborg
Bertil Stening
Fredrik Oeberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medivir AB
Original Assignee
Medivir AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medivir AB filed Critical Medivir AB
Publication of DE3780814D1 publication Critical patent/DE3780814D1/de
Application granted granted Critical
Publication of DE3780814T2 publication Critical patent/DE3780814T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE8888900484T 1986-12-19 1987-12-16 Verwendung von nukleosiden zur herstellung eines medikamentes zur behandlung von krankheiten, die durch einen retrovirus oder den hepatitis-b-virus verursacht werden. Expired - Fee Related DE3780814T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8605503A SE8605503D0 (sv) 1986-12-19 1986-12-19 Novel medicinal use
PCT/SE1987/000608 WO1988004662A1 (en) 1986-12-19 1987-12-16 Use of nucleosides for the manufacture of medicament for treatment of diseases caused by retrovirus or hepatitis b virus

Publications (2)

Publication Number Publication Date
DE3780814D1 DE3780814D1 (de) 1992-09-03
DE3780814T2 true DE3780814T2 (de) 1992-12-10

Family

ID=20366710

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888900484T Expired - Fee Related DE3780814T2 (de) 1986-12-19 1987-12-16 Verwendung von nukleosiden zur herstellung eines medikamentes zur behandlung von krankheiten, die durch einen retrovirus oder den hepatitis-b-virus verursacht werden.

Country Status (9)

Country Link
EP (1) EP0294443B1 (de)
JP (1) JPH01501551A (de)
AT (1) ATE78824T1 (de)
AU (1) AU607965B2 (de)
CA (1) CA1306695C (de)
DE (1) DE3780814T2 (de)
DK (1) DK462688A (de)
SE (1) SE8605503D0 (de)
WO (1) WO1988004662A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68917479D1 (de) * 1988-02-24 1994-09-15 Inst Rech Chim Biolog Derivate von deoxy-2'-uridin substituiert in der 5, 3' oder 5' stellung durch acylierte alpha-amino-gruppen, verfahren zur herstellung und arzneimittel daraus.
SE8802173D0 (sv) * 1988-06-10 1988-06-10 Astra Ab Pyrimidine derivatives
SE8802687D0 (sv) * 1988-07-20 1988-07-20 Astra Ab Nucleoside derivatives
DD293498A5 (de) * 1989-07-20 1991-09-05 Zi Fuer Molekularbiologie Der Adw,De Verfahren zur herstellung eines mittels fuer die behandlung oder prophylaxe von hepatits-infektionen bei mensch und tier
US6001840A (en) * 1990-03-06 1999-12-14 Southern Research Institute Methods of treatment of viral infections using carbocyclic deoxyguanosine analogs
GB9012899D0 (en) * 1990-06-09 1990-08-01 Wellcome Found Anti-hbv pyrimidine nucleoside
GB9125271D0 (en) * 1991-11-27 1992-01-29 Wellcome Found Anti-hbv pyrimidine nucleoside
JPH10507763A (ja) * 1994-10-24 1998-07-28 ジェネンコア インターナショナル インコーポレーテッド Ｌ−ピラノシルヌクレオシド
US5559101A (en) * 1994-10-24 1996-09-24 Genencor International, Inc. L-ribofuranosyl nucleosides
AU2002326736B2 (en) * 2001-08-24 2007-08-02 Koronis Pharmaceuticals, Inc. Mutagenic nucleoside analogs for the treatment of viral disease
CA2470938A1 (en) * 2001-12-20 2003-07-03 Raymond F. Schinazi Treatment of ebv and khsv infection and associated abnormal cellular proliferation
US8697357B2 (en) 2008-03-12 2014-04-15 Japan Advanced Institute Of Science And Technology Method for detection of methylcytosine using photoresponsive probe

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3328388A (en) * 1964-09-02 1967-06-27 Merck & Co Inc Arabinofuranosyl pyrimidines and methods of preparing same
DE1620185C3 (de) * 1966-03-02 1982-01-14 Robugen Gmbh Pharmazeutische Fabrik Esslingen A.N., 7300 Esslingen 5-Äthyl- und 5-Propyl-2'-deoxyuridin, Verfahren zur Herstellung dieser Verbindungen und diese Verbindungen enthaltende Arzneimittel
AT281862B (de) * 1968-07-11 1970-06-10 Robugen Gmbh Verfahren zur Herstellung von neuen 2'-Desoxyuridinen
GB1601020A (en) * 1978-04-24 1981-10-21 Stichting Grega Vzw 2'-deoxy-5 (2-halogenovinyl)-uridines
US4267171A (en) * 1979-07-02 1981-05-12 The Regents Of The University Of California C-5 Substituted cytosine nucleosides
US4247544A (en) * 1979-07-02 1981-01-27 The Regents Of The University Of California C-5 Substituted uracil nucleosides
JPS5639019A (en) * 1979-09-05 1981-04-14 Yamasa Shoyu Co Ltd Antiviral agent
GB2060604B (en) * 1979-10-03 1983-11-23 Univ Birmingham And Stichting E15-(2-halogenovinyl)-2'-deoxycytidines
JPS5687599A (en) * 1979-12-19 1981-07-16 Yamasa Shoyu Co Ltd E 55 22halogenovinyl arabinofuranosyluracil and its preparation
DE3045375A1 (de) * 1980-12-02 1982-07-01 Robugen Gmbh Pharmazeutische Fabrik Esslingen A.N., 7300 Esslingen Neue substituierte pyrimidin-nukleoside mit antiviraler wirkung, verfahren zu deren herstellung und daraus zubereitete arzneiformen
FI832884A (fi) * 1982-08-17 1984-02-18 Sandoz Ag Desoxiuridinderivat, deras framstaellningsfoerfaranden och anvaendning som farmaceutiska medel
JPS5979658A (ja) * 1982-10-28 1984-05-08 Fujitsu Ltd 複合交換機
FI85978C (fi) * 1985-03-16 1992-06-25 Wellcome Found Foerfarande foer framstaellning av ett terapeutiskt anvaendbart salt eller ester av 3'-azido-3'deoxitymidin.
WO1987004929A1 (en) * 1986-02-20 1987-08-27 Greer Sheldon B Composition for and method of treating aids and certain related diseases

Also Published As

Publication number Publication date
DE3780814D1 (de) 1992-09-03
AU607965B2 (en) 1991-03-21
DK462688D0 (da) 1988-08-18
JPH01501551A (ja) 1989-06-01
CA1306695C (en) 1992-08-25
EP0294443B1 (de) 1992-07-29
AU1083488A (en) 1988-07-15
DK462688A (da) 1988-08-18
WO1988004662A1 (en) 1988-06-30
EP0294443A1 (de) 1988-12-14
ATE78824T1 (de) 1992-08-15
SE8605503D0 (sv) 1986-12-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee