DE3876124T2 - Immunoassay fuer thrombomodulin. - Google Patents

Immunoassay fuer thrombomodulin.

Info

Publication number
DE3876124T2
DE3876124T2 DE19883876124 DE3876124T DE3876124T2 DE 3876124 T2 DE3876124 T2 DE 3876124T2 DE 19883876124 DE19883876124 DE 19883876124 DE 3876124 T DE3876124 T DE 3876124T DE 3876124 T2 DE3876124 T2 DE 3876124T2
Authority
DE
Germany
Prior art keywords
thrombomodulin
antibody
human thrombomodulin
binding
thrombin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE19883876124
Other languages
German (de)
English (en)
Other versions
DE3876124D1 (en
Inventor
Hidemi Ishii
Mutsuyoshi Kazama
Masahiko Nakano
Jiro Tsubouchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Gas Chemical Co Inc
Original Assignee
Mitsubishi Gas Chemical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Gas Chemical Co Inc filed Critical Mitsubishi Gas Chemical Co Inc
Publication of DE3876124D1 publication Critical patent/DE3876124D1/de
Application granted granted Critical
Publication of DE3876124T2 publication Critical patent/DE3876124T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/7452—Thrombomodulin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE19883876124 1987-04-01 1988-03-29 Immunoassay fuer thrombomodulin. Expired - Fee Related DE3876124T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7750787 1987-04-01

Publications (2)

Publication Number Publication Date
DE3876124D1 DE3876124D1 (en) 1993-01-07
DE3876124T2 true DE3876124T2 (de) 1993-05-06

Family

ID=13635877

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19883876124 Expired - Fee Related DE3876124T2 (de) 1987-04-01 1988-03-29 Immunoassay fuer thrombomodulin.

Country Status (3)

Country Link
EP (1) EP0285511B1 (ref)
JP (1) JPS6447391A (ref)
DE (1) DE3876124T2 (ref)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6445398A (en) * 1987-08-13 1989-02-17 Kowa Co Antithrombin-binding substance monoclonal antibody, hybridoma producing said antibody and method for purifying and measuring thrombin-binding substance utilizing said monoclonal antibody
WO1991006857A1 (en) * 1989-11-02 1991-05-16 Teijin Limited Immunoassay of human thrombomodulin, and reagent and kit therefor
JP2509001B2 (ja) * 1989-11-02 1996-06-19 帝人株式会社 ヒト・トロンボモジユリンの免疫学的測定方法、そのための試薬及びそのためのキツト
JPH0736019B2 (ja) * 1989-12-27 1995-04-19 富士薬品工業株式会社 新規な抗ヒトトロンボモジュリンモノクローナル抗体によるヒトトロンボモジュリンおよびその分解産物の定量方法
JP3358819B2 (ja) * 1996-12-26 2002-12-24 第一ファインケミカル株式会社 尿検体処理剤
WO2001048479A1 (fr) * 1999-12-28 2001-07-05 Fuji Chemical Industries, Ltd. Procede de determination de la possibilite d'avortement spontane ou d'accouchement premature et reactif associe
JP5579385B2 (ja) 2006-10-06 2014-08-27 旭化成ファーマ株式会社 播種性血管内血液凝固症候群の治療及び／又は改善剤
BR112014011488B1 (pt) 2011-11-15 2022-07-05 Asahi Kasei Pharma Corporation Medicamento para tratamento terapêutico e/ou melhora de sépsis
BR112014028852A2 (pt) 2012-05-31 2018-04-24 Asahi Kasei Pharma Corporation agente para o tratamento profilático e/ou terapêutico de dor neuropática periférica causada por agente anticâncer.
KR102768798B1 (ko) 2018-09-28 2025-02-14 아사히 가세이 파마 가부시키가이샤 항악성 종양제에 의한 말초 신경 장애의 증상 경감 및/또는 발증 억제를 위한 의약
BR112021007460A2 (pt) 2018-10-22 2021-11-03 Asahi Kasei Pharma Corp Medicamento para tratamento terapêutico e/ou melhora de um paciente com sepse

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0239644A4 (en) * 1985-06-28 1987-10-27 Asahi Chemical Ind NEW PHYSIOLOGICALLY ACTIVE AGENTS WITH A BLOOD COAGULATING REGULATORY EFFECT.
US5047503A (en) * 1986-07-15 1991-09-10 Kowa Company, Ltd. Thrombin-binding substance and process for its preparation

Also Published As

Publication number Publication date
JPH0542920B2 (ref) 1993-06-30
EP0285511A2 (en) 1988-10-05
JPS6447391A (en) 1989-02-21
EP0285511B1 (en) 1992-11-25
DE3876124D1 (en) 1993-01-07
EP0285511A3 (en) 1988-12-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee