DE3855947D1 - Peptide mit den immunologischen Eigenschaften von HIV-2 - Google Patents

Peptide mit den immunologischen Eigenschaften von HIV-2

Info

Publication number
DE3855947D1
DE3855947D1 DE3855947T DE3855947T DE3855947D1 DE 3855947 D1 DE3855947 D1 DE 3855947D1 DE 3855947 T DE3855947 T DE 3855947T DE 3855947 T DE3855947 T DE 3855947T DE 3855947 D1 DE3855947 D1 DE 3855947D1
Authority
DE
Germany
Prior art keywords
hiv
peptides
immunological properties
peptidic
siv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3855947T
Other languages
English (en)
Other versions
DE3855947T2 (de
Inventor
Marc Alizon
Luc Montagnier
Denise Guetard
Francois Clavel
Pierre Sonigo
Mireille Guyader
Pierre Tiollais
Lisa Chakrabarti
Ronald Desrosiers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Original Assignee
Institut Pasteur de Lille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27251436&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3855947(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/003,764 external-priority patent/US5051496A/en
Priority claimed from FR8701739A external-priority patent/FR2610632B1/fr
Priority claimed from FR8705398A external-priority patent/FR2614025B1/fr
Application filed by Institut Pasteur de Lille filed Critical Institut Pasteur de Lille
Publication of DE3855947D1 publication Critical patent/DE3855947D1/de
Application granted granted Critical
Publication of DE3855947T2 publication Critical patent/DE3855947T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • G01N33/56988HIV or HTLV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16211Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/15Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
    • G01N2333/155Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
    • G01N2333/16HIV-1, HIV-2
    • G01N2333/162HIV-1, HIV-2 env, e.g. gp160, gp110/120, gp41, V3, peptid T, DC4-Binding site
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/20Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • AIDS & HIV (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
DE3855947T 1987-01-16 1988-01-15 Peptide mit den immunologischen Eigenschaften von HIV-2 Expired - Lifetime DE3855947T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/003,764 US5051496A (en) 1986-01-22 1987-01-16 Peptides related to human immunodeficiency virus II (HIV-2)
FR8701739A FR2610632B1 (fr) 1987-02-11 1987-02-11 Peptides caracteristiques des retrovirus d'immunodeficience humaine (virus hiv) leurs applications au diagnostic des infections dues a certains de ces virus et, le cas echeant, a la vaccination contre le sida
FR8705398A FR2614025B1 (fr) 1987-04-15 1987-04-15 Peptides susceptibles d'etre reconnus par des anticorps induits contre des retrovirus d'immunodeficience humaine (virus hiv) leurs applications au diagnostic des infections dues a certains de ces virus et, le cas echeant, a la vaccination contre le sida

Publications (2)

Publication Number Publication Date
DE3855947D1 true DE3855947D1 (de) 1997-07-31
DE3855947T2 DE3855947T2 (de) 1997-12-11

Family

ID=27251436

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3855947T Expired - Lifetime DE3855947T2 (de) 1987-01-16 1988-01-15 Peptide mit den immunologischen Eigenschaften von HIV-2

Country Status (9)

Country Link
EP (1) EP0283327B1 (de)
JP (5) JP2948823B2 (de)
AT (1) ATE154808T1 (de)
AU (1) AU608294B2 (de)
DE (1) DE3855947T2 (de)
DK (1) DK174705B1 (de)
ES (1) ES2104556T3 (de)
GR (1) GR3024823T3 (de)
WO (1) WO1988005440A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8701628D0 (sv) * 1987-04-16 1987-04-16 Erling Norrby Medel for analys mm
AU2914889A (en) * 1987-08-28 1989-04-17 Board Of Regents, The University Of Texas System Prophylaxis and therapy of acquired immunodeficiency syndrome
DE3879881D1 (de) * 1987-11-16 1993-05-06 Hoffmann La Roche Rekombinante hiv-2 polypeptide.
US5780038A (en) * 1987-11-16 1998-07-14 Roche Diagnostic Systems, Inc. HIV-2 envelope polypeptides
AU3063389A (en) * 1988-01-08 1989-08-01 Dpz Deutsches Primatenzentrum Gesellschaft M.B.H. Hiv-2-type retroviruses of primates, vaccines, diagnostic and pharmaceutical compositions
JP3093763B2 (ja) * 1988-06-09 2000-10-03 インスティチュート・パスツール ヒトレトロウィルスhiv―2の外被糖タンパク質の前駆抗原及びそれと免疫学的同族性をもつ抗原、ならびにこれらの抗原の調製方法及び診断への応用
FR2632644B1 (fr) * 1988-06-10 1994-11-04 Pasteur Institut Antigenes precurseurs des glycoproteines d'enveloppe d'un retrovirus humain hiv-2 et antigenes presentant une parente immunologique avec ces derniers. preparation de ces antigenes. application au diagnostic
ATE134195T1 (de) * 1988-06-10 1996-02-15 United Biomedical Inc Peptidfragmente von hiv
IL90553A0 (en) * 1988-06-13 1990-01-18 Us Health Protein and coding sequence for detection and differentiation of siv and hiv-2 group of viruses
FR2635532B1 (fr) * 1988-07-29 1992-05-22 Pasteur Institut Particules hbsag recombinantes hybrides : caracteristiques morphologiques de l'antigene hbsag contenant 1 sequence immunogene induisant des anticorps neutralisants diriges contre hiv ou susceptible d'etre reconnue par de tels anticorps; sequences nucleotidiques codant pour de telles particules; vaccins les contenant
EP0362927A3 (de) * 1988-10-06 1990-11-14 Akzo N.V. Mit HIV-Antikörpern immunochemisch reaktive synthetische Polypeptide
CA2003383A1 (en) * 1988-11-23 1990-05-23 Sushil G. Devare Synthetic dna derived recombinant hiv antigens
US5260189A (en) * 1988-12-20 1993-11-09 Immunodiagnostics, Inc. Synthetic HIV-like peptides their compositions and uses
SG48125A1 (en) * 1989-05-12 1998-04-17 Pasteur Institut Antigenes of the envelope transmembrance glcoprotein of a human retrovirus of the hiv-2 type and antigens presenting with them an immunological relationship
FR2646854A1 (fr) * 1989-05-12 1990-11-16 Pasteur Institut Antigenes de la glycoproteine transmembranaire d'enveloppe d'un retrovirus humain du type hiv-2 antigenes presentant avec eux une parente immunologique
ES2083388T3 (es) * 1989-05-31 1996-04-16 Pasteur Institut Anticuerpos dirigidos contra proteinas y glucoproteinas del retrovirus vih-2 eho - aplicaciones para el diagnostico.
DK0806484T3 (da) * 1989-06-02 2006-08-14 Pasteur Institut Syntese af proteiner eller polypeptider kodet af en nucleotidsekvens af HIV-1, HIV-2 eller SIV.
US7022814B1 (en) 1992-01-21 2006-04-04 Institut Pasteur And Institut National De La Sante Et De La Recherche Medicale Nucleotide sequences derived from the genome of retroviruses of the HIV-1, HIV-2 and SIV type, and their uses in particular for the amplification of the genomes of these retroviruses and for the in vitro diagnosis of the diseases due to these viruses
FR2647810B1 (fr) * 1989-06-02 1994-07-22 Pasteur Institut Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus
FR2647809B1 (fr) * 1989-06-02 1991-09-20 Pasteur Institut Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-1, hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus
DE3934366A1 (de) * 1989-10-14 1991-04-18 Chemotherapeutisches Forschungsinstitut Georg Speyer Haus Vakzine zum schutz vor hiv-virusinfektionen, verfahren zu ihrer herstellung und ihre verwendung als diagnostikum und immuntherapeutikum
US6248574B1 (en) * 1989-12-13 2001-06-19 Avigdor Shaffermann Polypeptides selectively reactive with antibodies against human immunodeficiency virus and vaccines comprising the polypeptides
EP0438332B1 (de) * 1990-01-16 1998-04-08 Orgenics Ltd. Peptide, von Virus-HIV-Hüllen-Glycoproteinen abstammend, deren Verwendung zum Nachweis einer Infektion dieser Viren und für die Impfung gegen AIDS
FR2657016B1 (fr) * 1990-01-16 1995-08-25 Clonatec Sa Peptides derivant de la glycoproteine d'enveloppe du virus-hiv-2, leurs applications a la detection d'une infection due a ce virus et a la vaccination contre le sida.
DE4002636A1 (de) * 1990-01-30 1991-08-01 Boehringer Mannheim Gmbh Expression von hiv1- und 2-polypeptiden und deren verwendung
WO1992021377A1 (en) * 1991-06-03 1992-12-10 Syntello Inc. Peptides for use in induction of t cell activation against hiv-1
EP1752545A3 (de) 1991-12-23 2007-12-26 Novartis Vaccines and Diagnostics, Inc. HIV Sonden für ein Sandwich-Hybridisierungsverfahren in Lösung
JPH0748276A (ja) * 1992-03-26 1995-02-21 Inmeru:Kk Hiv感染症予防ワクチンおよびその製造法
US6479055B1 (en) 1993-06-07 2002-11-12 Trimeris, Inc. Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
DE4405810A1 (de) 1994-02-23 1995-08-24 Behringwerke Ag Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung
EP1878805B1 (de) * 1997-08-01 2010-05-12 Bio-Rad Laboratories, Inc. Synthetisches Antigen zum Nachweis von HIV-immunreaktiven Antikörpern
DE19908766C2 (de) * 1999-02-19 2001-02-15 Ulrich Schubert Verwendung synthetischer Vpr-Peptide des Humanen Immundefizienzvirus Typ 1 (HIV-1) zur Entwicklung von therapeutischen und diagnostischen Reagenzien
WO2005097822A1 (en) * 2004-04-09 2005-10-20 University Of Manitoba Identification of the precise amino acid sequence of the epitope recognized by the potent neutralizing human anti-hiv-1 monoclonal antibody igg1b12
EP1778282B1 (de) * 2004-08-17 2016-03-30 Institut Gustave Roussy Mutiertes hiv nef zur modulation der immunität
WO2007141650A2 (en) * 2006-01-17 2007-12-13 Instituto De Medicina Molecular Compositions and methods for diagnosing hiv-2 infection

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EP0201540B2 (de) * 1984-10-18 2001-10-31 Institut Pasteur Lymphadenopathie-assoziierte hüllenantigene und deren verwendungen
AU600658B2 (en) * 1984-12-24 1990-08-23 Genentech Inc. Molecularly cloned acquired immunodeficiency syndrome polypeptides and their methods of use
DK171119B1 (da) * 1985-04-19 1996-06-17 Hoffmann La Roche AIDS-viruskappeprotein, ekspressionsvektor bærende viruskappeproteinet, transformanter transformeret med ekspressionsvektoren, fremgangsmåde til fremstilling af viruskappeproteinet, fremgangsmåde til detektion af AIDS-antistoffer, fremgangsmåde til bestemmelse af AIDS-virus, vaccine mod AIDS, antistoffer mod viruskappeproteinet samt anvendelse af dette til fremstilling af en vaccine og til testnin
US4629783A (en) * 1985-04-29 1986-12-16 Genetic Systems Corporation Synthetic antigen for the detection of AIDS-related disease
DE3533440A1 (de) * 1985-09-19 1987-03-26 Hoechst Ag N-substituierte 3,4,5,6-tetrahydrophthalimide, verfahren zu ihrer herstellung sowie ihre verwendung im pflanzenschutz
GR862412B (en) * 1985-09-25 1987-01-23 Oncogen Vaccines and immuinoassays for acquired immune deficiency syndrome
PT84182B (pt) * 1986-01-22 1989-09-14 Pasteur Institut Novo retrovirus susceptivel de provocar o sida, meios e processos para a sua deteccao "in vitro"
FR2593189B1 (fr) * 1986-01-22 1989-10-20 Pasteur Institut Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida
EP0269520A3 (de) * 1986-11-21 1988-08-24 Institut Pasteur Zum Hervorrufen von AIDS geeignetes Retrovirus vom HIV-2-Typ sowie seine Antigen- und Nukleinsäurebestandteile
JP3105581B2 (ja) * 1991-07-03 2000-11-06 内橋エステック株式会社 面状温度ヒュ−ズ
JPH0833969A (ja) * 1994-07-22 1996-02-06 Toyota Motor Corp 加圧鋳造方法

Also Published As

Publication number Publication date
AU1225088A (en) 1988-08-10
EP0283327B1 (de) 1997-06-25
GR3024823T3 (en) 1998-01-30
JPH07300498A (ja) 1995-11-14
DK174705B1 (da) 2003-09-29
ES2104556T3 (es) 1997-10-16
EP0283327A2 (de) 1988-09-21
ATE154808T1 (de) 1997-07-15
JPH01502119A (ja) 1989-07-27
DE3855947T2 (de) 1997-12-11
JPH11322792A (ja) 1999-11-24
DK513388D0 (da) 1988-09-15
WO1988005440A1 (fr) 1988-07-28
AU608294B2 (en) 1991-03-28
JP2862810B2 (ja) 1999-03-03
EP0283327A3 (de) 1989-01-04
JP2948823B2 (ja) 1999-09-13
JP2002030099A (ja) 2002-01-29
JP2004002421A (ja) 2004-01-08
DK513388A (da) 1988-11-16

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