DE3854470D1 - Verfahren für Affinitätsuntersuchungen durch Verwendung von Ziel-Amplifizierung. - Google Patents

Verfahren für Affinitätsuntersuchungen durch Verwendung von Ziel-Amplifizierung.

Info

Publication number
DE3854470D1
DE3854470D1 DE3854470T DE3854470T DE3854470D1 DE 3854470 D1 DE3854470 D1 DE 3854470D1 DE 3854470 T DE3854470 T DE 3854470T DE 3854470 T DE3854470 T DE 3854470T DE 3854470 D1 DE3854470 D1 DE 3854470D1
Authority
DE
Germany
Prior art keywords
procedure
target amplification
target
affinity testing
affinity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3854470T
Other languages
English (en)
Other versions
DE3854470T2 (de
Inventor
Mark Leo Collins
Donald Neil Halbert
Walter King
Jonathan Michael Lawrie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BP Corp North America Inc
Original Assignee
BP Corp North America Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BP Corp North America Inc filed Critical BP Corp North America Inc
Application granted granted Critical
Publication of DE3854470D1 publication Critical patent/DE3854470D1/de
Publication of DE3854470T2 publication Critical patent/DE3854470T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00445—Other cooling arrangements

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DE3854470T 1987-12-21 1988-12-21 Verfahren für Affinitätsuntersuchungen durch Verwendung von Ziel-Amplifizierung. Expired - Lifetime DE3854470T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13692087A 1987-12-21 1987-12-21

Publications (2)

Publication Number Publication Date
DE3854470D1 true DE3854470D1 (de) 1995-10-19
DE3854470T2 DE3854470T2 (de) 1996-03-28

Family

ID=22475015

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3854470T Expired - Lifetime DE3854470T2 (de) 1987-12-21 1988-12-21 Verfahren für Affinitätsuntersuchungen durch Verwendung von Ziel-Amplifizierung.

Country Status (5)

Country Link
EP (1) EP0328829B1 (de)
JP (1) JP2817926B2 (de)
AT (1) ATE127854T1 (de)
AU (1) AU2735988A (de)
DE (1) DE3854470T2 (de)

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US5714380A (en) 1986-10-23 1998-02-03 Amoco Corporation Closed vessel for isolating target molecules and for performing amplification
AU623602B2 (en) * 1987-06-19 1992-05-21 Akzo Nobel N.V. Transcription-based nucleic acid amplification/detection systems
IE61148B1 (en) * 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
AU633036B2 (en) * 1988-12-09 1993-01-21 Chemicon International, Inc. Amplified dna assay
AU5401290A (en) * 1989-04-05 1990-11-05 Gene-Trak Systems Hybridization promotion reagents
EP0478630B1 (de) * 1989-06-12 1993-09-01 Cis Bio International Verfahren zum nachweis von spezifischen sequenzen von nukleinsäuren und ihre verwendungen
US5200314A (en) * 1990-03-23 1993-04-06 Chiron Corporation Polynucleotide capture assay employing in vitro amplification
WO1991015599A1 (en) * 1990-04-05 1991-10-17 Amrad Corporation Limited A method for detecting dna
AU7575291A (en) * 1990-04-06 1991-10-30 Syngene, Inc. Process and composition for performing dna assays
US5670316A (en) * 1990-05-07 1997-09-23 Daikin Industries, Ltd. Diagnostic applications of double D-loop formation
RU2017821C1 (ru) * 1990-10-10 1994-08-15 Анатолий Михайлович Онищенко Способ амплификации днк и устройство для его осуществления
EP0533952A4 (en) * 1991-04-15 1993-07-07 Sumitomo Electric Industries, Ltd. Process for separating or extracting nucleic acid from specimen containing the same
WO1992020820A1 (en) * 1991-05-15 1992-11-26 Vanderbilt University Method to determine metastatic potential of tumor cells
US5437976A (en) * 1991-08-08 1995-08-01 Arizona Board Of Regents, The University Of Arizona Multi-domain DNA ligands bound to a solid matrix for protein and nucleic acid affinity chromatography and processing of solid-phase DNA
EP0693964A1 (de) * 1992-04-23 1996-01-31 Amoco Corporation Geschlossener behälter zur isolation von ziel-molekülen und zur verstärkung
US5312730A (en) * 1992-05-27 1994-05-17 Ciba Corning Diagnostics Corp. Immune complex transfer with lypophilic bridge
JPH08503606A (ja) * 1992-10-09 1996-04-23 アモコ・コーポレーション 検定法
AU707391B2 (en) * 1994-05-28 1999-07-08 Tepnel Medical Limited Producing copies of nucleic acids
WO1998045684A1 (en) * 1997-04-04 1998-10-15 Biosite Diagnostics, Inc. Methods for concentrating ligands using magnetic particles
ES2271994T3 (es) 1997-05-02 2007-04-16 Gen-Probe Incorporated Hibridacion en dos pasos y captura de un polinucleotido.
US6534273B2 (en) 1997-05-02 2003-03-18 Gen-Probe Incorporated Two-step hybridization and capture of a polynucleotide
AU2012232986B2 (en) * 1998-05-01 2014-06-12 Gen-Probe Incorporated System and method for incubating the contents of a reaction receptacle
AU2014277869B2 (en) * 1998-05-01 2015-04-30 Gen-Probe Incorporated System and method for incubating the contents of a reaction receptacle
ATE363339T1 (de) 1998-05-01 2007-06-15 Gen Probe Inc Rührvorrichtung für den fluiden inhalt eines behälters
US8337753B2 (en) 1998-05-01 2012-12-25 Gen-Probe Incorporated Temperature-controlled incubator having a receptacle mixing mechanism
KR100446358B1 (ko) * 2000-03-31 2004-09-01 산코 준야쿠 가부시키가이샤 프로우브 중합체 제작용 프로우브, 프로우브 중합체의 제작방법 및 그 이용
FR2811321A1 (fr) * 2000-07-04 2002-01-11 Bio Merieux Amplificateur d'une region ribonucleique cible d'un arn ribosomal 16s ou adn pour un tel arn d'une espece eubacterienne et detection de telles especes
US20030148273A1 (en) * 2000-08-26 2003-08-07 Shoulian Dong Target enrichment and amplification
DE10119468A1 (de) * 2001-04-12 2002-10-24 Epigenomics Ag Mikroarray-Verfahren zur Anreicherung von DNA-Fragmenten aus komplexen Mischungen
US8030465B2 (en) 2001-06-29 2011-10-04 Medimolecular Pty Ltd Nucleic acid ligands to complex targets
AU2002362013B2 (en) * 2001-11-21 2008-04-24 Applied Biosystems, Llc. Digital assay
JP5897780B2 (ja) 2005-01-28 2016-03-30 デューク ユニバーシティ プリント回路基板上の液滴操作装置及び方法
US9051601B2 (en) * 2006-08-01 2015-06-09 Gen-Probe Incorporated Methods of nonspecific target capture of nucleic acids
WO2008045158A1 (en) 2006-10-10 2008-04-17 Illumina, Inc. Compositions and methods for representational selection of nucleic acids fro complex mixtures using hybridization
GB0701253D0 (en) 2007-01-23 2007-02-28 Diagnostics For The Real World Nucleic acid amplification and testing
EP2053132A1 (de) 2007-10-23 2009-04-29 Roche Diagnostics GmbH Anreicherung und Sequenzanalyse von Genombereichen
DE102007056398A1 (de) * 2007-11-23 2009-05-28 Febit Holding Gmbh Flexibles Extraktionsverfahren für die Herstellung sequenzspezifischer Molekülbibliotheken
US20100331204A1 (en) * 2009-02-13 2010-12-30 Jeff Jeddeloh Methods and systems for enrichment of target genomic sequences
CN103543282A (zh) 2010-07-23 2014-01-29 贝克曼考尔特公司 用于处理化验盒的系统
ES2844324T3 (es) 2011-11-07 2021-07-21 Beckman Coulter Inc Brazo robótico
KR20140091033A (ko) 2011-11-07 2014-07-18 베크만 컬터, 인코포레이티드 검체 컨테이너 검출
BR112014011035A2 (pt) 2011-11-07 2017-06-13 Beckman Coulter, Inc. sistema de aliquotagem e fluxo de trabalho
BR112014010955A2 (pt) 2011-11-07 2017-06-06 Beckman Coulter Inc sistema e método para processar amostras
ES2729283T3 (es) 2011-11-07 2019-10-31 Beckman Coulter Inc Sistema de centrífuga y flujo de trabajo
US8973736B2 (en) 2011-11-07 2015-03-10 Beckman Coulter, Inc. Magnetic damping for specimen transport system
AU2014256903B2 (en) * 2013-04-25 2020-09-24 Firefly Bioworks, Inc. Multiplexed analysis of target nucleic acids
US10550440B2 (en) 2016-02-26 2020-02-04 Arizona Board Of Regents On Behalf Of Arizona State University Synthetic translation-sensing riboswitches and uses thereof
JP7232438B2 (ja) * 2018-04-27 2023-03-03 国立大学法人 東京大学 メチル含有基修飾核酸を精製、分離または濃縮する方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0154505B1 (de) * 1984-02-28 1992-09-30 Ortho Diagnostic Systems Inc. Diagnose von Genmissbildungen durch Restriktionskarte-Analysierung unter Anwendung eines Sandwichhybridisierungsformats
CA1260372A (en) * 1984-04-27 1989-09-26 Elazar Rabbani Hybridization method for the detection of genetic materials
US4734363A (en) * 1984-11-27 1988-03-29 Molecular Diagnostics, Inc. Large scale production of DNA probes
GB8507706D0 (en) * 1985-03-25 1985-05-01 Genetics Int Inc Magnetic nucleic acid sequences
DK171161B1 (da) * 1985-03-28 1996-07-08 Hoffmann La Roche Fremgangsmåde til påvisning af forekomst eller fravær af mindst én specifik nukleinsyresekvens i en prøve eller til skelnen mellem to forskellige nukleinsyresekvenser i denne prøve
EP0236491A1 (de) * 1985-09-18 1987-09-16 Yale University Reca-nukleoprotein-filament und verfahren
ZA877772B (en) * 1986-10-23 1988-04-20 Amoco Corporation Target and background capture methods and apparatus for affinity assays

Also Published As

Publication number Publication date
ATE127854T1 (de) 1995-09-15
DE3854470T2 (de) 1996-03-28
EP0328829B1 (de) 1995-09-13
JPH01211500A (ja) 1989-08-24
EP0328829A2 (de) 1989-08-23
JP2817926B2 (ja) 1998-10-30
EP0328829A3 (en) 1990-09-19
AU2735988A (en) 1989-07-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN