DE3834636C2 - - Google Patents

Info

Publication number
DE3834636C2
DE3834636C2 DE3834636A DE3834636A DE3834636C2 DE 3834636 C2 DE3834636 C2 DE 3834636C2 DE 3834636 A DE3834636 A DE 3834636A DE 3834636 A DE3834636 A DE 3834636A DE 3834636 C2 DE3834636 C2 DE 3834636C2
Authority
DE
Germany
Prior art keywords
dna
primer
primers
dna sequence
chain reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3834636A
Other languages
German (de)
English (en)
Other versions
DE3834636A1 (de
Inventor
Herbert Dr. 7400 Tuebingen De Jaeckle
Diethard Dr. 8000 Muenchen De Tautz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Original Assignee
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6364896&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3834636(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Max Planck Gesellschaft zur Foerderung der Wissenschaften eV filed Critical Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Priority to DE3834636A priority Critical patent/DE3834636A1/de
Priority to AT89912096T priority patent/ATE161585T1/de
Priority to DE58909827T priority patent/DE58909827D1/de
Priority to EP89912096A priority patent/EP0438512B2/de
Priority to PCT/EP1989/001203 priority patent/WO1990004040A1/de
Priority to JP51115289A priority patent/JP3218318B2/ja
Publication of DE3834636A1 publication Critical patent/DE3834636A1/de
Publication of DE3834636C2 publication Critical patent/DE3834636C2/de
Application granted granted Critical
Priority to US08/145,617 priority patent/US5766847A/en
Priority to HK98103477A priority patent/HK1004341A1/xx
Priority to US09/591,383 priority patent/USRE37984E1/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE3834636A 1988-10-11 1988-10-11 Verfahren zur analyse von laengenpolymorphismen in dna-bereichen Granted DE3834636A1 (de)

Priority Applications (9)

Application Number Priority Date Filing Date Title
DE3834636A DE3834636A1 (de) 1988-10-11 1988-10-11 Verfahren zur analyse von laengenpolymorphismen in dna-bereichen
PCT/EP1989/001203 WO1990004040A1 (de) 1988-10-11 1989-10-11 Verfahren zur analyse von längenpolymorphismen in dna-bereichen
DE58909827T DE58909827D1 (de) 1988-10-11 1989-10-11 Verfahren zur analyse von längenpolymorphismen in dna-bereichen
EP89912096A EP0438512B2 (de) 1988-10-11 1989-10-11 Verfahren zur analyse von längenpolymorphismen in dna-bereichen
AT89912096T ATE161585T1 (de) 1988-10-11 1989-10-11 Verfahren zur analyse von längenpolymorphismen in dna-bereichen
JP51115289A JP3218318B2 (ja) 1988-10-11 1989-10-11 Ｄｎａ領域における長さ多型を分析する方法
US08/145,617 US5766847A (en) 1988-10-11 1993-11-04 Process for analyzing length polymorphisms in DNA regions
HK98103477A HK1004341A1 (en) 1988-10-11 1998-04-24 Process for analysing length polymorphisms in dna domains
US09/591,383 USRE37984E1 (en) 1988-10-11 2000-06-09 Process for analyzing length polymorphisms in DNA regions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3834636A DE3834636A1 (de) 1988-10-11 1988-10-11 Verfahren zur analyse von laengenpolymorphismen in dna-bereichen

Publications (2)

Publication Number Publication Date
DE3834636A1 DE3834636A1 (de) 1990-04-19
DE3834636C2 true DE3834636C2 (US06566495-20030520-M00010.png) 1992-02-20

Family

ID=6364896

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3834636A Granted DE3834636A1 (de) 1988-10-11 1988-10-11 Verfahren zur analyse von laengenpolymorphismen in dna-bereichen
DE58909827T Expired - Lifetime DE58909827D1 (de) 1988-10-11 1989-10-11 Verfahren zur analyse von längenpolymorphismen in dna-bereichen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE58909827T Expired - Lifetime DE58909827D1 (de) 1988-10-11 1989-10-11 Verfahren zur analyse von längenpolymorphismen in dna-bereichen

Country Status (7)

Country Link
US (1) USRE37984E1 (US06566495-20030520-M00010.png)
EP (1) EP0438512B2 (US06566495-20030520-M00010.png)
JP (1) JP3218318B2 (US06566495-20030520-M00010.png)
AT (1) ATE161585T1 (US06566495-20030520-M00010.png)
DE (2) DE3834636A1 (US06566495-20030520-M00010.png)
HK (1) HK1004341A1 (US06566495-20030520-M00010.png)
WO (1) WO1990004040A1 (US06566495-20030520-M00010.png)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6238863B1 (en) 1998-02-04 2001-05-29 Promega Corporation Materials and methods for indentifying and analyzing intermediate tandem repeat DNA markers
US7008771B1 (en) 1994-09-30 2006-03-07 Promega Corporation Multiplex amplification of short tandem repeat loci
WO2018011101A1 (en) 2016-07-12 2018-01-18 Mautner Martín Eduardo Methods for using long ssdna polynucleotides as primers in pcr assays

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9002259A (nl) * 1990-10-17 1992-05-18 Eurodiagnostics B V Werkwijze voor het bepalen van een genotype door het vergelijken van de nucleotidensequentie van leden van een genfamilie, alsmede kit voor het opsporen van genetische variaties.
US5364759B2 (en) * 1991-01-31 1999-07-20 Baylor College Medicine Dna typing with short tandem repeat polymorphisms and identification of polymorphic short tandem repeats
WO1992013968A1 (en) * 1991-02-07 1992-08-20 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Monolocus-specific hypervariable probes
US6207373B1 (en) 1998-02-25 2001-03-27 Nanogen, Inc. Methods for determining nature of repeat units in DNA
AU704660B2 (en) * 1994-11-28 1999-04-29 E.I. Du Pont De Nemours And Company Compound microsatellite primers for the detection of genetic polymorphisms
AU4174397A (en) 1996-08-30 1998-03-19 Life Technologies, Inc. Methods for identification and isolation of specific nucleotide sequences in cdna and genomic dna
US6306588B1 (en) 1997-02-07 2001-10-23 Invitrogen Corporation Polymerases for analyzing or typing polymorphic nucleic acid fragments and uses thereof
GB9713597D0 (en) 1997-06-28 1997-09-03 Sec Dep Of The Home Department Improvements in and relating to forensic identification
JP3738268B2 (ja) 2003-02-24 2006-01-25 森永乳業株式会社 インターロイキン−６産生抑制剤
NZ542981A (en) 2003-03-14 2008-05-30 Meiji Dairies Corp Compositions against infection with rotavirus infection and processes for producing the same
WO2004083432A1 (en) 2003-03-21 2004-09-30 Academisch Ziekenhuis Leiden Modulation of exon recognition in pre-mrna by interfering with the secondary rna structure
US20050112591A1 (en) * 2003-11-25 2005-05-26 Applera Corporation Novel method for isolating single stranded product
WO2007123391A1 (en) 2006-04-20 2007-11-01 Academisch Ziekenhuis Leiden Therapeutic intervention in a genetic disease in an individual by modifying expression of an aberrantly expressed gene.
EP1857548A1 (en) 2006-05-19 2007-11-21 Academisch Ziekenhuis Leiden Means and method for inducing exon-skipping
CA2660523C (en) 2006-08-11 2019-03-19 Prosensa Technologies B.V. Methods and means for treating dna repeat instability associated genetic disorders
CN101790385A (zh) 2007-07-12 2010-07-28 普罗森那技术公司 用于使化合物靶向多种选定器官、组织或肿瘤细胞的分子
AU2008273096B2 (en) 2007-07-12 2013-05-02 Academisch Ziekenhuis Leiden Molecules for targeting compounds to various selected organs or tissues
EP2614827B1 (en) 2007-10-26 2017-06-28 Academisch Ziekenhuis Leiden Means and methods for counteracting muscle disorders
USRE48468E1 (en) 2007-10-26 2021-03-16 Biomarin Technologies B.V. Means and methods for counteracting muscle disorders
JP2011510678A (ja) 2008-02-08 2011-04-07 プロセンサ ホールディング ビーブイ Ｄｎａ反復不安定性関連遺伝性障害を治療するための方法及び手段
EP2119783A1 (en) 2008-05-14 2009-11-18 Prosensa Technologies B.V. Method for efficient exon (44) skipping in Duchenne Muscular Dystrophy and associated means
EP2421971B1 (en) 2009-04-24 2016-07-06 BioMarin Technologies B.V. Oligonucleotide comprising an inosine for treating dmd
ES2616561T3 (es) 2009-12-24 2017-06-13 Biomarin Technologies B.V. Molécula para tratar un trastorno inflamatorio
EP4043039A1 (en) 2012-01-27 2022-08-17 BioMarin Technologies B.V. Rna modulating oligonucleotides with improved characteristics for the treatment of duchenne and becker muscular dystrophy
GB201418980D0 (en) 2014-10-24 2014-12-10 Univ Portsmouth Cell assay kit and method

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0342717A3 (en) 1984-11-12 1990-04-25 THE LISTER INSTITUTE OF PREVENTIVE MEDICINE Royal National Orthopaedic Hospital Polynucleotide probes
IS1355B6 (is) 1984-11-12 1989-04-19 Lister Institute Of Preventive Medicine Fjölkjarna kannar
DK171161B1 (da) * 1985-03-28 1996-07-08 Hoffmann La Roche Fremgangsmåde til påvisning af forekomst eller fravær af mindst én specifik nukleinsyresekvens i en prøve eller til skelnen mellem to forskellige nukleinsyresekvenser i denne prøve
CA1284931C (en) * 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
US4987066A (en) 1986-11-07 1991-01-22 Max Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Process for the detection of restriction fragment length polymorphisms in eukaryotic genomes
JPH05501946A (ja) 1988-02-18 1993-04-15 ユニバーシティ・オブ・ユタ 可変数タンデム反復座のｄｎａプローブを使用する遺伝的同定
US5075217A (en) 1989-04-21 1991-12-24 Marshfield Clinic Length polymorphisms in (dC-dA)n ·(dG-dT)n sequences
US5364759B2 (en) 1991-01-31 1999-07-20 Baylor College Medicine Dna typing with short tandem repeat polymorphisms and identification of polymorphic short tandem repeats

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7008771B1 (en) 1994-09-30 2006-03-07 Promega Corporation Multiplex amplification of short tandem repeat loci
US6238863B1 (en) 1998-02-04 2001-05-29 Promega Corporation Materials and methods for indentifying and analyzing intermediate tandem repeat DNA markers
US6767703B2 (en) 1998-02-04 2004-07-27 Promega Corporation Materials and methods for identifying and analyzing intermediate tandem repeat DNA markers
EP2287307A2 (en) 1998-02-04 2011-02-23 Promega Corporation Materials and methods for identifying and analyzing intermediate tandem repeat DNA markers
EP2287308A2 (en) 1998-02-04 2011-02-23 Promega Corporation Materials and methods for identifying and analyzing intermediate tandem repeat DNA markers
WO2018011101A1 (en) 2016-07-12 2018-01-18 Mautner Martín Eduardo Methods for using long ssdna polynucleotides as primers in pcr assays

Also Published As

Publication number Publication date
EP0438512B2 (de) 2005-07-27
JPH04501207A (ja) 1992-03-05
ATE161585T1 (de) 1998-01-15
WO1990004040A1 (de) 1990-04-19
EP0438512A1 (de) 1991-07-31
DE58909827D1 (de) 1998-02-05
DE3834636A1 (de) 1990-04-19
USRE37984E1 (en) 2003-02-11
EP0438512B1 (de) 1997-12-29
JP3218318B2 (ja) 2001-10-15
HK1004341A1 (en) 1998-11-20

Similar Documents

Publication Publication Date Title
DE3834636C2 (US06566495-20030520-M00010.png)
DE69434314T2 (de) Polymorphismus von mononukleotiden und ihre verwendung in der genanalyse
DE68929299T3 (de) Multiple genomische DNA-Verstärkung zum Nachweis einer Deletion
US5766847A (en) Process for analyzing length polymorphisms in DNA regions
DE69814639T3 (de) Nicht-invasive pränatale diagnose
DE69736637T2 (de) Multiplex amplifikation kurzer tandem repeat loci
DE60029876T2 (de) Verfahren und Oligonukleotide zum Nachweis von Nukleinsäuresequenzvariationen
DE60014067T2 (de) Zusammensetzungen und verfahren zur genetischen analyse
DE3904270A1 (de) Verfahren zur markierung bestimmter chromosomen unter verwendung repetetiver rekombinations dns
DE69823372T2 (de) Verfahren und reagentiensatz zur amplifizierung, sequenzierung und typisierung von hla i genen
EP0846186B1 (de) Extraktion, amplifikation und sequentielle hybridisierung von pilzzellen-dna sowie verfahren zum nachweisen von pilzzellen in klinischem material
DE69637018T2 (de) Verfahren zur diagnose der erblichen hemochromatosis
EP1960537A1 (de) Verfahren zur bestimmung des genotyps aus einer biologischen probe enthaltend nukleinsäuren unterschiedlicher individuen
GB2206586A (en) Polynucleotide probes
DE60025871T2 (de) Genetisches Screening Verfahren und Vorrichtung
DE60116500T2 (de) Dna/rna-einbettungsmedium und verfahren zur verwendung
EP0698122B1 (de) Mittel zur komplexen diagnostik der genexpression und verfahren zur anwendung für die medizinische diagnostik und die genisolierung
WO1999042610A1 (de) VERFAHREN ZUR CHARAKTERISIERUNG VON mRNA-MOLEKÜLEN
EP0879300B1 (de) Verwendung von primern für universelle fingerprint-analysen
DE69838278T2 (de) Verfahren zur diganose und feststellung der prädisposition von bipolaren gemütserkrankungen
DE19955024C2 (de) Diagnose-Kit
DE60109002T2 (de) Methode zum Nachweis von transkribierten genomischen DNA-Sequenzen
DE10014575A1 (de) Verfahren zur Identifizierung von Organismen durch vergleichende genetische Analyse sowie Primer und Hybridisationssonden zur Durchführung des Verfahrens
DE4416446A1 (de) Für menschliche DNA spezifische Sequenzen
DE10242359A1 (de) Verfahren zur Amplifikation genetischer Informationen

Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
D2 Grant after examination
8364 No opposition during term of opposition