HK1004341A1 - Process for analysing length polymorphisms in dna domains - Google Patents

Process for analysing length polymorphisms in dna domains

Info

Publication number
HK1004341A1
HK1004341A1 HK98103477A HK98103477A HK1004341A1 HK 1004341 A1 HK1004341 A1 HK 1004341A1 HK 98103477 A HK98103477 A HK 98103477A HK 98103477 A HK98103477 A HK 98103477A HK 1004341 A1 HK1004341 A1 HK 1004341A1
Authority
HK
Hong Kong
Prior art keywords
primer
annealing
dna
analysing
length polymorphisms
Prior art date
Application number
HK98103477A
Inventor
Herbert Jackle
Diethard Tautz
Original Assignee
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6364896&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1004341(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Max Planck Gesellschaft filed Critical Max Planck Gesellschaft
Publication of HK1004341A1 publication Critical patent/HK1004341A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A process for analyzing length polymorphism in DNA regions wherein the following steps are carried out:(a) annealing at least one primer pair to the DNA to be analyzed, wherein one of the molecules of the primer pair is substantially complementary to one of the complementary strands of the 5' or 3' flank of a simple or cryptically simple DNA sequence, and wherein the annealing occurs in such an orientation that the synthesis products obtained by a primer-controlled polymerisation reaction with one of said primers can serve as template for annealing the other primer after denaturation;(b) primer-controlled polymerase chain reaction; and(c) separating and analyzing the polymerase chain reaction products.
HK98103477A 1988-10-11 1998-04-24 Process for analysing length polymorphisms in dna domains HK1004341A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3834636A DE3834636A1 (en) 1988-10-11 1988-10-11 METHOD FOR ANALYZING LENGTH POLYMORPHISMS IN DNA AREAS
PCT/EP1989/001203 WO1990004040A1 (en) 1988-10-11 1989-10-11 Process for analysing length polymorphisms in dna domains

Publications (1)

Publication Number Publication Date
HK1004341A1 true HK1004341A1 (en) 1998-11-20

Family

ID=6364896

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98103477A HK1004341A1 (en) 1988-10-11 1998-04-24 Process for analysing length polymorphisms in dna domains

Country Status (7)

Country Link
US (1) USRE37984E1 (en)
EP (1) EP0438512B2 (en)
JP (1) JP3218318B2 (en)
AT (1) ATE161585T1 (en)
DE (2) DE3834636A1 (en)
HK (1) HK1004341A1 (en)
WO (1) WO1990004040A1 (en)

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NL9002259A (en) * 1990-10-17 1992-05-18 Eurodiagnostics B V METHOD FOR DETERMINING A GENOTYPE BY COMPARING THE NUCLEOTID SEQUENCE OF MEM FAMILY MEMBERS AND KIT FOR DETECTING GENETIC VARIATIONS.
US5364759B2 (en) * 1991-01-31 1999-07-20 Baylor College Medicine Dna typing with short tandem repeat polymorphisms and identification of polymorphic short tandem repeats
WO1992013968A1 (en) * 1991-02-07 1992-08-20 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Monolocus-specific hypervariable probes
US6207373B1 (en) 1998-02-25 2001-03-27 Nanogen, Inc. Methods for determining nature of repeat units in DNA
US7008771B1 (en) 1994-09-30 2006-03-07 Promega Corporation Multiplex amplification of short tandem repeat loci
EP0804618B1 (en) * 1994-11-28 1999-01-27 E.I. Du Pont De Nemours And Company Compound microsatellite primers for the detection of genetic polymorphisms
EP1007730A4 (en) 1996-08-30 2004-04-28 Invitrogen Corp METHODS FOR IDENTIFICATION AND ISOLATION OF SPECIFIC NUCLEOTIDE SEQUENCES IN cDNA AND GENOMIC DNA
US6306588B1 (en) 1997-02-07 2001-10-23 Invitrogen Corporation Polymerases for analyzing or typing polymorphic nucleic acid fragments and uses thereof
GB9713597D0 (en) 1997-06-28 1997-09-03 Sec Dep Of The Home Department Improvements in and relating to forensic identification
US6238863B1 (en) 1998-02-04 2001-05-29 Promega Corporation Materials and methods for indentifying and analyzing intermediate tandem repeat DNA markers
NZ537089A (en) 2003-02-24 2007-07-27 Morinaga Milk Industry Co Ltd Interleukin 6 production inhibitor
CN1787829B (en) 2003-03-14 2010-06-16 明治乳业株式会社 Composition against infection with rotavirus and process for producing the same
WO2004083432A1 (en) 2003-03-21 2004-09-30 Academisch Ziekenhuis Leiden Modulation of exon recognition in pre-mrna by interfering with the secondary rna structure
US20050112591A1 (en) * 2003-11-25 2005-05-26 Applera Corporation Novel method for isolating single stranded product
WO2007123391A1 (en) 2006-04-20 2007-11-01 Academisch Ziekenhuis Leiden Therapeutic intervention in a genetic disease in an individual by modifying expression of an aberrantly expressed gene.
EP1857548A1 (en) 2006-05-19 2007-11-21 Academisch Ziekenhuis Leiden Means and method for inducing exon-skipping
ATE524547T1 (en) 2006-08-11 2011-09-15 Prosensa Technologies Bv SINGLE STRANDED OLIGONUCLEOTIDES COMPLEMENTARY TO REPETITIVE ELEMENTS FOR THE TREATMENT OF DNA REPEATS-INSTABILITY-ASSOCIATED DISEASES
CA2693048C (en) 2007-07-12 2016-10-18 Prosensa Technologies B.V. Molecules for targeting compounds to various selected organs or tissues
AU2008273094B2 (en) 2007-07-12 2013-05-09 Prosensa Technologies B.V. Molecules for targeting compounds to various selected organs, tissues or tumor cells
USRE48468E1 (en) 2007-10-26 2021-03-16 Biomarin Technologies B.V. Means and methods for counteracting muscle disorders
CA2704049A1 (en) 2007-10-26 2009-04-30 Academisch Ziekenhuis Leiden Means and methods for counteracting muscle disorders
JP2011510678A (en) 2008-02-08 2011-04-07 プロセンサ ホールディング ビーブイ Methods and means for treating DNA repeat instability related genetic disorders
EP2119783A1 (en) 2008-05-14 2009-11-18 Prosensa Technologies B.V. Method for efficient exon (44) skipping in Duchenne Muscular Dystrophy and associated means
AU2010239779A1 (en) 2009-04-24 2011-11-17 Prosensa Technologies B.V. Oligonucleotide comprising an inosine for treating DMD
AU2010335039B2 (en) 2009-12-24 2015-03-26 Academisch Ziekenhuis Leiden H.O.D.N. Lumc Molecule for treating an inflammatory disorder
CN104203289B (en) 2012-01-27 2020-11-03 比奥马林技术公司 RNA-regulatory oligonucleotides with improved properties for the treatment of duchenne muscular dystrophy and becker muscular dystrophy
GB201418980D0 (en) 2014-10-24 2014-12-10 Univ Portsmouth Cell assay kit and method
US10822647B2 (en) 2016-07-12 2020-11-03 Biodynamics S.R.L. Methods for using long ssDNA polynucleotides as primers (superprimers) in PCR assays

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IS1355B6 (en) 1984-11-12 1989-04-19 Lister Institute Of Preventive Medicine Multicolor explores
EP0342717A3 (en) 1984-11-12 1990-04-25 THE LISTER INSTITUTE OF PREVENTIVE MEDICINE Royal National Orthopaedic Hospital Polynucleotide probes
DK171161B1 (en) * 1985-03-28 1996-07-08 Hoffmann La Roche A method for detecting the presence or absence of at least one specific nucleic acid sequence in a sample or for distinguishing two different nucleic acid sequences in this sample
CA1284931C (en) * 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
US4987066A (en) 1986-11-07 1991-01-22 Max Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Process for the detection of restriction fragment length polymorphisms in eukaryotic genomes
DE68929070T2 (en) 1988-02-18 2000-05-25 The University Of Utah, Salt Lake City USE OF DNA SAMPLES WITH VARIABLE NUMBER OF TANDEM REPETITIVE SITES FOR GENETIC IDENTIFICATION
US5075217A (en) 1989-04-21 1991-12-24 Marshfield Clinic Length polymorphisms in (dC-dA)n ·(dG-dT)n sequences
US5364759B2 (en) 1991-01-31 1999-07-20 Baylor College Medicine Dna typing with short tandem repeat polymorphisms and identification of polymorphic short tandem repeats

Also Published As

Publication number Publication date
EP0438512B2 (en) 2005-07-27
JPH04501207A (en) 1992-03-05
DE3834636A1 (en) 1990-04-19
EP0438512A1 (en) 1991-07-31
WO1990004040A1 (en) 1990-04-19
DE58909827D1 (en) 1998-02-05
USRE37984E1 (en) 2003-02-11
JP3218318B2 (en) 2001-10-15
EP0438512B1 (en) 1997-12-29
DE3834636C2 (en) 1992-02-20
ATE161585T1 (en) 1998-01-15

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Legal Events

Date Code Title Description
PF Patent in force
AM43 Amendment of standard patent following opposition or revocation proceedings in the designated patent office (acc. sect 43 patent ordinance)
PE Patent expired

Effective date: 20091010