DE3688225D1 - Herstellung menschlichen somatomedins c. - Google Patents
Herstellung menschlichen somatomedins c.Info
- Publication number
- DE3688225D1 DE3688225D1 DE8686902217T DE3688225T DE3688225D1 DE 3688225 D1 DE3688225 D1 DE 3688225D1 DE 8686902217 T DE8686902217 T DE 8686902217T DE 3688225 T DE3688225 T DE 3688225T DE 3688225 D1 DE3688225 D1 DE 3688225D1
- Authority
- DE
- Germany
- Prior art keywords
- dna sequences
- somatomedin
- optimal
- production
- manufacturing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 title abstract 2
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 title abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 4
- 235000021120 animal protein Nutrition 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Compounds Of Unknown Constitution (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858507833A GB8507833D0 (en) | 1985-03-26 | 1985-03-26 | Production of human somatomedin c |
| PCT/US1986/000579 WO1986005810A1 (en) | 1985-03-26 | 1986-03-25 | Production of human somatomedin c |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3688225D1 true DE3688225D1 (de) | 1993-05-13 |
| DE3688225T2 DE3688225T2 (de) | 1993-07-22 |
Family
ID=10576658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8686902217T Expired - Lifetime DE3688225T2 (de) | 1985-03-26 | 1986-03-25 | Herstellung menschlichen somatomedins c. |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0215110B1 (de) |
| JP (4) | JPH0691832B2 (de) |
| CN (1) | CN1034588C (de) |
| AT (1) | ATE87977T1 (de) |
| AU (1) | AU594950B2 (de) |
| CA (1) | CA1339305C (de) |
| DE (1) | DE3688225T2 (de) |
| DK (1) | DK175223B1 (de) |
| ES (1) | ES8705921A1 (de) |
| GB (1) | GB8507833D0 (de) |
| IL (1) | IL78278A0 (de) |
| NO (1) | NO302709B1 (de) |
| WO (1) | WO1986005810A1 (de) |
| ZA (1) | ZA862240B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU612594B2 (en) * | 1986-09-12 | 1991-07-18 | Genentech Inc. | Human prorelaxin |
| GB8712540D0 (en) * | 1987-05-28 | 1987-07-01 | Ucb Sa | Expression of human proapolipoprotein a-i |
| US4876242A (en) * | 1987-09-21 | 1989-10-24 | Merck & Co., Inc. | Human insulin-like growth factor analoges with reduced binding to serum carrier proteins and their production in yeast |
| AUPP807899A0 (en) * | 1999-01-08 | 1999-02-04 | University Of Queensland, The | Codon utilization |
| JP6018719B1 (ja) * | 2016-03-15 | 2016-11-02 | Ｂｘ新生精機株式会社 | シャッター開閉機の巻上装置 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ207842A (en) * | 1983-04-25 | 1988-02-12 | Chiron Corp | Production of human insulin-like growth factor (igf) using cdna |
| IL71991A (en) * | 1983-06-06 | 1994-05-30 | Genentech Inc | Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes |
| SE8303626D0 (sv) * | 1983-06-23 | 1983-06-23 | Kabigen Ab | A recombinant plasmid a transformant microorganism, a polydoxyrebonucleotide segment, a process for producing a biologically active protein, and the protein thus produced |
| EP0151760A1 (de) * | 1984-01-06 | 1985-08-21 | Takeda Chemical Industries, Ltd. | DNA und ihre Verwendung |
| US4758512A (en) * | 1984-03-06 | 1988-07-19 | President And Fellows Of Harvard College | Hosts and methods for producing recombinant products in high yields |
-
1985
- 1985-03-26 GB GB858507833A patent/GB8507833D0/en active Pending
-
1986
- 1986-03-21 CA CA000504757A patent/CA1339305C/en not_active Expired - Lifetime
- 1986-03-25 DE DE8686902217T patent/DE3688225T2/de not_active Expired - Lifetime
- 1986-03-25 EP EP86902217A patent/EP0215110B1/de not_active Expired - Lifetime
- 1986-03-25 JP JP61501992A patent/JPH0691832B2/ja not_active Expired - Lifetime
- 1986-03-25 AT AT86902217T patent/ATE87977T1/de not_active IP Right Cessation
- 1986-03-25 ES ES553374A patent/ES8705921A1/es not_active Expired
- 1986-03-25 ZA ZA862240A patent/ZA862240B/xx unknown
- 1986-03-25 AU AU56657/86A patent/AU594950B2/en not_active Expired
- 1986-03-25 WO PCT/US1986/000579 patent/WO1986005810A1/en active IP Right Grant
- 1986-03-26 CN CN86102889A patent/CN1034588C/zh not_active Expired - Lifetime
- 1986-03-26 IL IL78278A patent/IL78278A0/xx unknown
- 1986-11-25 NO NO864724A patent/NO302709B1/no unknown
- 1986-11-26 DK DK198605698A patent/DK175223B1/da not_active IP Right Cessation
-
1994
- 1994-05-09 JP JP6117430A patent/JP2568383B2/ja not_active Expired - Lifetime
- 1994-05-09 JP JP6117443A patent/JP2602628B2/ja not_active Expired - Lifetime
- 1994-05-09 JP JP6117435A patent/JPH07102152B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE3688225T2 (de) | 1993-07-22 |
| EP0215110A4 (de) | 1987-07-09 |
| GB8507833D0 (en) | 1985-05-01 |
| ES553374A0 (es) | 1987-05-16 |
| EP0215110A1 (de) | 1987-03-25 |
| CA1339305C (en) | 1997-08-19 |
| JPH07102152B2 (ja) | 1995-11-08 |
| WO1986005810A1 (en) | 1986-10-09 |
| JP2602628B2 (ja) | 1997-04-23 |
| JPH07143885A (ja) | 1995-06-06 |
| ATE87977T1 (de) | 1993-04-15 |
| NO864724L (no) | 1987-01-23 |
| ES8705921A1 (es) | 1987-05-16 |
| DK569886A (da) | 1986-11-26 |
| EP0215110B1 (de) | 1993-04-07 |
| JP2568383B2 (ja) | 1997-01-08 |
| AU5665786A (en) | 1986-10-23 |
| JPS62502305A (ja) | 1987-09-10 |
| NO302709B1 (no) | 1998-04-14 |
| ZA862240B (en) | 1986-11-26 |
| CN86102889A (zh) | 1986-11-26 |
| JPH07143896A (ja) | 1995-06-06 |
| DK569886D0 (da) | 1986-11-26 |
| CN1034588C (zh) | 1997-04-16 |
| JPH07145200A (ja) | 1995-06-06 |
| DK175223B1 (da) | 2004-07-12 |
| IL78278A0 (en) | 1986-07-31 |
| JPH0691832B2 (ja) | 1994-11-16 |
| AU594950B2 (en) | 1990-03-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: BIOGEN IDEC MA INC., CAMBRIDGE, MASS., US |