DE3686597T2 - Uricase und verfahren zu deren herstellung. - Google Patents

Uricase und verfahren zu deren herstellung.

Info

Publication number
DE3686597T2
DE3686597T2 DE8686107416T DE3686597T DE3686597T2 DE 3686597 T2 DE3686597 T2 DE 3686597T2 DE 8686107416 T DE8686107416 T DE 8686107416T DE 3686597 T DE3686597 T DE 3686597T DE 3686597 T2 DE3686597 T2 DE 3686597T2
Authority
DE
Germany
Prior art keywords
uricase
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686107416T
Other languages
English (en)
Other versions
DE3686597D1 (de
Inventor
Masachika Takashio
Takahide Chikano
Minoru Kamimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyobo Co Ltd
Original Assignee
Sapporo Breweries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sapporo Breweries Ltd filed Critical Sapporo Breweries Ltd
Application granted granted Critical
Publication of DE3686597D1 publication Critical patent/DE3686597D1/de
Publication of DE3686597T2 publication Critical patent/DE3686597T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0044—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7)
    • C12N9/0046—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7) with oxygen as acceptor (1.7.3)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
DE8686107416T 1985-06-05 1986-06-02 Uricase und verfahren zu deren herstellung. Expired - Lifetime DE3686597T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60120399A JPH0671425B2 (ja) 1985-06-05 1985-06-05 ウリカ−ゼおよびその製造法

Publications (2)

Publication Number Publication Date
DE3686597D1 DE3686597D1 (de) 1992-10-08
DE3686597T2 true DE3686597T2 (de) 1993-04-15

Family

ID=14785246

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686107416T Expired - Lifetime DE3686597T2 (de) 1985-06-05 1986-06-02 Uricase und verfahren zu deren herstellung.

Country Status (4)

Country Link
US (2) US4882280A (de)
EP (1) EP0204283B1 (de)
JP (1) JPH0671425B2 (de)
DE (1) DE3686597T2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0671428B2 (ja) * 1988-08-17 1994-09-14 サッポロビール株式会社 ウリカーゼのｄｎａ配列および製法
US5955336A (en) * 1988-08-17 1999-09-21 Toyo Boseki Kabushiki Kaisha DNA sequence for uricase and manufacturing process of uricase
US5728562A (en) * 1988-08-17 1998-03-17 Toyo Boseki Kabushiki Kaisha Isolated recombinant uricase
US6212089B1 (en) * 1996-03-19 2001-04-03 Hitachi, Ltd. Semiconductor memory device and defect remedying method thereof
JP2971218B2 (ja) * 1991-12-04 1999-11-02 協和醗酵工業株式会社 ウリカーゼ遺伝子およびウリカーゼの製造法
DK2316475T3 (da) 1998-08-06 2017-11-20 Mountain View Pharmaceuticals Inc Isoleret tetramer urikase
US7374905B2 (en) * 2000-11-08 2008-05-20 Oxyrase, Inc. Medium composition, method and device for selectively enhancing the isolation of anaerobic microorganisms contained in a mixed sample with facultative microorganisms
US6913915B2 (en) 2001-08-02 2005-07-05 Phoenix Pharmacologics, Inc. PEG-modified uricase
KR20070058522A (ko) 2004-09-13 2007-06-08 캐스케이드 마이크로테크 인코포레이티드 양측 프루빙 구조
MX2007012547A (es) 2005-04-11 2008-03-11 Savient Pharmaceuticals Inc Formas variantes de urato oxidasa y uso de las mismas.
US20080159976A1 (en) * 2005-04-11 2008-07-03 Jacob Hartman Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
US8148123B2 (en) * 2005-04-11 2012-04-03 Savient Pharmaceuticals, Inc. Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
CN101194016B (zh) 2005-04-11 2012-09-05 萨文特医药公司 尿酸氧化酶的变体形式及其用途
WO2006125452A1 (en) * 2005-05-23 2006-11-30 Universite De Geneve Injectable superparamagnetic nanoparticles for treatment by hyperthermia and use for forming an hyperthermic implant
PL2013225T3 (pl) * 2006-04-12 2015-06-30 Crealta Pharmaceuticals Llc Oczyszczanie białek z zastosowaniem kationowego środka powierzchniowo czynnego
JP5010291B2 (ja) * 2007-01-15 2012-08-29 シーシーアイ株式会社 新規ウリカーゼの製造方法
JP5053648B2 (ja) * 2007-01-15 2012-10-17 シーシーアイ株式会社 新規ウリカーゼの製造方法
JP5022044B2 (ja) * 2007-01-23 2012-09-12 シーシーアイ株式会社 新規ウリカーゼの製造方法
WO2010151823A1 (en) 2009-06-25 2010-12-29 Savient Pharmaceuticals Inc. Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy
US9441210B2 (en) 2013-06-26 2016-09-13 Food Industry Research And Development Institute Method of reducing levels of uric acid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR6301M (de) * 1967-03-29 1968-09-09
GB1221235A (en) * 1968-08-19 1971-02-03 Novo Terapeutisk Labor As A process for the production of uricase
IT1141061B (it) * 1980-09-19 1986-10-01 Anic Spa Procedimento per la produzione di uricasi
US4394450A (en) * 1982-03-01 1983-07-19 Miles Laboratories, Inc. Method for purification of uricase
JPH0657149B2 (ja) * 1986-01-13 1994-08-03 サッポロビール株式会社 ウレア−ゼ及びその製造法

Also Published As

Publication number Publication date
EP0204283A2 (de) 1986-12-10
JPS61280272A (ja) 1986-12-10
EP0204283B1 (de) 1992-09-02
US4987076A (en) 1991-01-22
US4882280A (en) 1989-11-21
DE3686597D1 (de) 1992-10-08
EP0204283A3 (en) 1988-07-20
JPH0671425B2 (ja) 1994-09-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: TOYO BOSEKI K.K., OSAKA, JP