DE3675134D1 - Verfahren zur herstellung von 2,5-dicetopiperazinen. - Google Patents
Verfahren zur herstellung von 2,5-dicetopiperazinen.Info
- Publication number
- DE3675134D1 DE3675134D1 DE8686870133T DE3675134T DE3675134D1 DE 3675134 D1 DE3675134 D1 DE 3675134D1 DE 8686870133 T DE8686870133 T DE 8686870133T DE 3675134 T DE3675134 T DE 3675134T DE 3675134 D1 DE3675134 D1 DE 3675134D1
- Authority
- DE
- Germany
- Prior art keywords
- dicetopiperazines
- producing
- unsubstituted
- substituted
- base
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/778,817 US4694081A (en) | 1985-09-23 | 1985-09-23 | Process to prepare 2,5-diketopiperazines |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3675134D1 true DE3675134D1 (de) | 1990-11-29 |
Family
ID=25114475
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686870133T Expired - Fee Related DE3675134D1 (de) | 1985-09-23 | 1986-09-22 | Verfahren zur herstellung von 2,5-dicetopiperazinen. |
Country Status (10)
Country | Link |
---|---|
US (1) | US4694081A (de) |
EP (1) | EP0216746B1 (de) |
JP (1) | JPS6272676A (de) |
AT (1) | ATE57694T1 (de) |
AU (1) | AU588626B2 (de) |
CA (1) | CA1257266A (de) |
DE (1) | DE3675134D1 (de) |
HU (1) | HU196382B (de) |
IL (1) | IL80108A (de) |
ZA (1) | ZA867212B (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4806538A (en) * | 1984-11-02 | 1989-02-21 | Fujisawa Pharmaceutical Co., Ltd. | Piperazine compound as PAF-antagonist |
US4992552A (en) * | 1988-08-31 | 1991-02-12 | Eastman Kodak Company | Process for preparation of amino acids |
JPH04234374A (ja) * | 1990-12-27 | 1992-08-24 | Ajinomoto Co Inc | ジケトピペラジン誘導体の製造方法 |
US5208375A (en) * | 1991-07-02 | 1993-05-04 | Mallinckrodt Medical, Inc. | Compositions for magnetic resonance imaging |
US5874589A (en) * | 1997-07-18 | 1999-02-23 | Glaxo Wellcome, Inc. | Methods for synthesizing diverse collections of tetramic acids and derivatives thereof |
AU2001284697A1 (en) * | 2000-08-04 | 2002-02-18 | Dmi Biosciences, Inc. | Method of synthesizing diketopiperazines |
CN100553636C (zh) | 2000-08-04 | 2009-10-28 | Dmi生物科学公司 | 二酮基哌嗪和包含它们的组合物的使用方法 |
KR100542820B1 (ko) * | 2002-09-17 | 2006-01-20 | 이재호 | 옥사릴 클로라이드를 이용한 1-에틸-2,3-디옥소피페라진의제조방법 |
AU2003279761B2 (en) * | 2002-10-02 | 2009-11-12 | Luoxis Diagnostics, Inc. | Diagnosis and monitoring of diseases |
CN103191409A (zh) | 2003-05-15 | 2013-07-10 | Dmi生物科学公司 | T-细胞介导的疾病的治疗 |
US8217047B2 (en) * | 2008-05-27 | 2012-07-10 | Dmi Acquisition Corp. | Therapeutic methods and compounds |
US8116047B2 (en) * | 2008-12-18 | 2012-02-14 | Sandisk Technologies Inc. | Electrostatic discharge protective circuit having rise time detector and discharge sustaining circuitry |
EP2594134B1 (de) * | 2010-07-15 | 2017-08-02 | Republic of Korea (Management: Rural Development Administration) | Verwendung einer agrochemikalie mit einem 2,5-diketopiperazinderivat als wirkstoff |
EP2613786A4 (de) | 2010-09-07 | 2013-10-23 | Dmi Acquisition Corp | Behandlung von erkrankungen |
JP2014530063A (ja) | 2011-10-10 | 2014-11-17 | アンピオ ファーマシューティカルズ,インコーポレイテッド | 免疫寛容が高められた埋込み型医療用デバイス、ならびに製造方法および埋込み方法 |
PL2766029T3 (pl) | 2011-10-10 | 2020-08-24 | Ampio Pharmaceuticals, Inc. | Leczenie choroby zwyrodnieniowej stawów |
KR20140095479A (ko) | 2011-10-28 | 2014-08-01 | 앰피오 파마슈티컬스 인코퍼레이티드 | 비염의 치료 |
US9808454B2 (en) | 2013-03-15 | 2017-11-07 | Ampio Pharmaceuticals, Inc. | Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same |
AU2015305611B2 (en) | 2014-08-18 | 2020-04-23 | Ampio Pharmaceuticals, Inc. | Treatment of joint conditions |
US11389512B2 (en) | 2015-06-22 | 2022-07-19 | Ampio Pharmaceuticals, Inc. | Use of low molecular weight fractions of human serum albumin in treating diseases |
WO2021195265A1 (en) | 2020-03-24 | 2021-09-30 | Ampio Pharmaceuticals, Inc. | Methods for treating diseases associated with respiratory viruses |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2913496A (en) * | 1957-06-07 | 1959-11-17 | Du Pont | N-(2-hydroxyethyl)-n'-pentenyl-ethylenediamine |
DE1189553B (de) * | 1962-08-09 | 1965-03-25 | Degussa | Verfahren zur Herstellung von racemischen und optisch aktiven Piperazinderivaten |
US4140791A (en) * | 1978-05-30 | 1979-02-20 | Chevron Research Company | 1,4-Di-(2,6-dimethylphenyl)-2,5-piperazinedione and its fungicidal use |
JPS5618969A (en) * | 1979-07-24 | 1981-02-23 | Toyama Chem Co Ltd | Novel 1-(4-aminobenzyl)-2,3-dioxopiperazine derivative, its acid addition salt, and their preparation |
US4400330A (en) * | 1982-07-29 | 1983-08-23 | Stauffer Chemical Company | Method for preparation of N-phosphonomethylglycine |
GB8427735D0 (en) * | 1984-11-02 | 1984-12-12 | Fujisawa Pharmaceutical Co | Piperazine compound |
US4804499A (en) * | 1985-09-23 | 1989-02-14 | Monsanto Company | Process for the preparation of N-substituted aminomethylphosphonic acids |
US4694082A (en) * | 1985-09-23 | 1987-09-15 | Monsanto Company | Compound 1,4-diisopropyl-2,5-diketopiperazine |
-
1985
- 1985-09-23 US US06/778,817 patent/US4694081A/en not_active Expired - Fee Related
-
1986
- 1986-09-22 CA CA000518770A patent/CA1257266A/en not_active Expired
- 1986-09-22 DE DE8686870133T patent/DE3675134D1/de not_active Expired - Fee Related
- 1986-09-22 AT AT86870133T patent/ATE57694T1/de active
- 1986-09-22 AU AU63034/86A patent/AU588626B2/en not_active Ceased
- 1986-09-22 EP EP86870133A patent/EP0216746B1/de not_active Expired - Lifetime
- 1986-09-22 HU HU864016A patent/HU196382B/hu not_active IP Right Cessation
- 1986-09-22 JP JP61222275A patent/JPS6272676A/ja active Pending
- 1986-09-22 ZA ZA867212A patent/ZA867212B/xx unknown
- 1986-09-22 IL IL80108A patent/IL80108A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP0216746B1 (de) | 1990-10-24 |
HU196382B (en) | 1988-11-28 |
EP0216746A2 (de) | 1987-04-01 |
IL80108A0 (en) | 1986-12-31 |
JPS6272676A (ja) | 1987-04-03 |
ATE57694T1 (de) | 1990-11-15 |
HUT41748A (en) | 1987-05-28 |
ZA867212B (en) | 1987-08-26 |
US4694081A (en) | 1987-09-15 |
EP0216746A3 (en) | 1987-09-09 |
AU6303486A (en) | 1987-03-26 |
AU588626B2 (en) | 1989-09-21 |
CA1257266A (en) | 1989-07-11 |
IL80108A (en) | 1991-07-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |