IL80108A - Process for preparing 1,4-diisopropyl-2,5-diketopiperazines - Google Patents
Process for preparing 1,4-diisopropyl-2,5-diketopiperazinesInfo
- Publication number
- IL80108A IL80108A IL80108A IL8010886A IL80108A IL 80108 A IL80108 A IL 80108A IL 80108 A IL80108 A IL 80108A IL 8010886 A IL8010886 A IL 8010886A IL 80108 A IL80108 A IL 80108A
- Authority
- IL
- Israel
- Prior art keywords
- diketopiperazines
- diisopropyl
- preparing
- unsubstituted
- substituted
- Prior art date
Links
- LCTYQXDHTHVMLH-UHFFFAOYSA-N 1,4-di(propan-2-yl)piperazine-2,5-dione Chemical class CC(C)N1CC(=O)N(C(C)C)CC1=O LCTYQXDHTHVMLH-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- BEBCJVAWIBVWNZ-UHFFFAOYSA-N glycinamide Chemical class NCC(N)=O BEBCJVAWIBVWNZ-UHFFFAOYSA-N 0.000 abstract 1
- -1 haloacetyl halide Chemical class 0.000 abstract 1
- 230000000269 nucleophilic effect Effects 0.000 abstract 1
- BXRNXXXXHLBUKK-UHFFFAOYSA-N piperazine-2,5-dione Chemical class O=C1CNC(=O)CN1 BXRNXXXXHLBUKK-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/778,817 US4694081A (en) | 1985-09-23 | 1985-09-23 | Process to prepare 2,5-diketopiperazines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL80108A0 IL80108A0 (en) | 1986-12-31 |
| IL80108A true IL80108A (en) | 1991-07-18 |
Family
ID=25114475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL80108A IL80108A (en) | 1985-09-23 | 1986-09-22 | Process for preparing 1,4-diisopropyl-2,5-diketopiperazines |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4694081A (de) |
| EP (1) | EP0216746B1 (de) |
| JP (1) | JPS6272676A (de) |
| AT (1) | ATE57694T1 (de) |
| AU (1) | AU588626B2 (de) |
| CA (1) | CA1257266A (de) |
| DE (1) | DE3675134D1 (de) |
| HU (1) | HU196382B (de) |
| IL (1) | IL80108A (de) |
| ZA (1) | ZA867212B (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4806538A (en) * | 1984-11-02 | 1989-02-21 | Fujisawa Pharmaceutical Co., Ltd. | Piperazine compound as PAF-antagonist |
| US4992552A (en) * | 1988-08-31 | 1991-02-12 | Eastman Kodak Company | Process for preparation of amino acids |
| JPH04234374A (ja) * | 1990-12-27 | 1992-08-24 | Ajinomoto Co Inc | ジケトピペラジン誘導体の製造方法 |
| US5208375A (en) * | 1991-07-02 | 1993-05-04 | Mallinckrodt Medical, Inc. | Compositions for magnetic resonance imaging |
| US5874589A (en) * | 1997-07-18 | 1999-02-23 | Glaxo Wellcome, Inc. | Methods for synthesizing diverse collections of tetramic acids and derivatives thereof |
| AU2001284697A1 (en) * | 2000-08-04 | 2002-02-18 | Dmi Biosciences, Inc. | Method of synthesizing diketopiperazines |
| AU2001279313B2 (en) | 2000-08-04 | 2007-03-01 | Ampio Pharmaceuticals, Inc. | Method of using diketopiperazines and composition containing them |
| KR100542820B1 (ko) * | 2002-09-17 | 2006-01-20 | 이재호 | 옥사릴 클로라이드를 이용한 1-에틸-2,3-디옥소피페라진의제조방법 |
| ATE520981T1 (de) * | 2002-10-02 | 2011-09-15 | Dmi Biosciences Inc | Diagnose und überwachung von krankheiten |
| CA3050734A1 (en) | 2003-05-15 | 2004-12-02 | Ampio Pharmaceuticals, Inc. | Treatment of t-cell mediated diseases |
| WO2009146320A1 (en) | 2008-05-27 | 2009-12-03 | Dmi Life Sciences, Inc. | Therapeutic methods and compounds |
| US8116047B2 (en) * | 2008-12-18 | 2012-02-14 | Sandisk Technologies Inc. | Electrostatic discharge protective circuit having rise time detector and discharge sustaining circuitry |
| US20130190177A1 (en) * | 2010-07-15 | 2013-07-25 | Kongju National University Industry- University Cooperation Foundation | Agricultural agent containing 2,5-diketopiperazine derivative as active ingredient |
| US8507496B2 (en) | 2010-09-07 | 2013-08-13 | Dmi Acquisition Corp. | Treatment of diseases |
| EP2766029B1 (de) | 2011-10-10 | 2020-03-25 | Ampio Pharmaceuticals, Inc. | Behandlung degenerativer gelenkerkrankungen |
| EA027343B1 (ru) | 2011-10-10 | 2017-07-31 | Ампио Фармасьютикалз, Инк. | Имплантируемые устройства медицинского назначения с повышенной иммунной толерантностью и способы изготовления и имплантирования |
| CA2846394A1 (en) | 2011-10-28 | 2013-05-02 | Ampio Pharmaceuticals, Inc. | Treatment of rhinitis |
| BR112015020469A2 (pt) | 2013-03-15 | 2020-01-28 | Ampio Pharmaceuticals Inc | Usos de da-dkp, composição e método para fornecimento de células-tronco a umindivíduo |
| AU2015305611B2 (en) | 2014-08-18 | 2020-04-23 | Ampio Pharmaceuticals, Inc. | Treatment of joint conditions |
| US11389512B2 (en) | 2015-06-22 | 2022-07-19 | Ampio Pharmaceuticals, Inc. | Use of low molecular weight fractions of human serum albumin in treating diseases |
| WO2021195265A1 (en) | 2020-03-24 | 2021-09-30 | Ampio Pharmaceuticals, Inc. | Methods for treating diseases associated with respiratory viruses |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2913496A (en) * | 1957-06-07 | 1959-11-17 | Du Pont | N-(2-hydroxyethyl)-n'-pentenyl-ethylenediamine |
| DE1189553B (de) * | 1962-08-09 | 1965-03-25 | Degussa | Verfahren zur Herstellung von racemischen und optisch aktiven Piperazinderivaten |
| US4140791A (en) * | 1978-05-30 | 1979-02-20 | Chevron Research Company | 1,4-Di-(2,6-dimethylphenyl)-2,5-piperazinedione and its fungicidal use |
| JPS5618969A (en) * | 1979-07-24 | 1981-02-23 | Toyama Chem Co Ltd | Novel 1-(4-aminobenzyl)-2,3-dioxopiperazine derivative, its acid addition salt, and their preparation |
| US4400330A (en) * | 1982-07-29 | 1983-08-23 | Stauffer Chemical Company | Method for preparation of N-phosphonomethylglycine |
| GB8427735D0 (en) * | 1984-11-02 | 1984-12-12 | Fujisawa Pharmaceutical Co | Piperazine compound |
| US4804499A (en) * | 1985-09-23 | 1989-02-14 | Monsanto Company | Process for the preparation of N-substituted aminomethylphosphonic acids |
| US4694082A (en) * | 1985-09-23 | 1987-09-15 | Monsanto Company | Compound 1,4-diisopropyl-2,5-diketopiperazine |
-
1985
- 1985-09-23 US US06/778,817 patent/US4694081A/en not_active Expired - Fee Related
-
1986
- 1986-09-22 HU HU864016A patent/HU196382B/hu not_active IP Right Cessation
- 1986-09-22 IL IL80108A patent/IL80108A/xx unknown
- 1986-09-22 ZA ZA867212A patent/ZA867212B/xx unknown
- 1986-09-22 AU AU63034/86A patent/AU588626B2/en not_active Ceased
- 1986-09-22 DE DE8686870133T patent/DE3675134D1/de not_active Expired - Lifetime
- 1986-09-22 AT AT86870133T patent/ATE57694T1/de active
- 1986-09-22 EP EP86870133A patent/EP0216746B1/de not_active Expired - Lifetime
- 1986-09-22 JP JP61222275A patent/JPS6272676A/ja active Pending
- 1986-09-22 CA CA000518770A patent/CA1257266A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ZA867212B (en) | 1987-08-26 |
| EP0216746A2 (de) | 1987-04-01 |
| HU196382B (en) | 1988-11-28 |
| AU588626B2 (en) | 1989-09-21 |
| DE3675134D1 (de) | 1990-11-29 |
| EP0216746B1 (de) | 1990-10-24 |
| EP0216746A3 (en) | 1987-09-09 |
| CA1257266A (en) | 1989-07-11 |
| ATE57694T1 (de) | 1990-11-15 |
| AU6303486A (en) | 1987-03-26 |
| US4694081A (en) | 1987-09-15 |
| IL80108A0 (en) | 1986-12-31 |
| HUT41748A (en) | 1987-05-28 |
| JPS6272676A (ja) | 1987-04-03 |
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