ES2002161A6 - Procedimiento para preparar 1,3-diazabiciclo (4.4.0)dec-2-en-4-onas antiarritmicas - Google Patents
Procedimiento para preparar 1,3-diazabiciclo (4.4.0)dec-2-en-4-onas antiarritmicasInfo
- Publication number
- ES2002161A6 ES2002161A6 ES8601961A ES8601961A ES2002161A6 ES 2002161 A6 ES2002161 A6 ES 2002161A6 ES 8601961 A ES8601961 A ES 8601961A ES 8601961 A ES8601961 A ES 8601961A ES 2002161 A6 ES2002161 A6 ES 2002161A6
- Authority
- ES
- Spain
- Prior art keywords
- diazabicyclo
- dec
- ones
- antiarrhytmic
- intermediates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR 1,3-DIAZABICICLO 4.4.0 DEC-2-EN-4-ONAS ANTIRRITMICAS, DE FORMULA (II) EN DONDE, NOEXCLUSIVAMENTE, R ES HIDROGENO, ALQUILO 1-6 C O FENILO. SE OBTIENEN POR ACILACION DE UN COMPUESTO DE FORMULA (III) Y CICLACION DEL COMPUESTO RESULTANTE DE FORMULA (I).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/777,661 US4791199A (en) | 1985-09-19 | 1985-09-19 | Process for antiarrhythmic 1,3-diazabicyclo[4.4.0]dec-2-en-4-ones |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2002161A6 true ES2002161A6 (es) | 1988-07-16 |
Family
ID=25110892
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8601961A Expired ES2002161A6 (es) | 1985-09-19 | 1986-09-17 | Procedimiento para preparar 1,3-diazabiciclo (4.4.0)dec-2-en-4-onas antiarritmicas |
Country Status (6)
Country | Link |
---|---|
US (1) | US4791199A (es) |
EP (1) | EP0215477A1 (es) |
JP (1) | JPS6270375A (es) |
AU (1) | AU589447B2 (es) |
ES (1) | ES2002161A6 (es) |
ZA (1) | ZA867114B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5061772A (en) * | 1987-05-07 | 1991-10-29 | The B. F. Goodrich Company | Process for making comb-shaped copolymers of a macromolecular monomer of polylactone with terminal acryloyl unsaturation, and compatible blends thereof |
KR102423013B1 (ko) | 2017-08-29 | 2022-07-21 | 다우 글로벌 테크놀로지스 엘엘씨 | 트리잉 지연제를 함유하는 폴리에틸렌 조성물 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4217306A (en) * | 1978-05-01 | 1980-08-12 | G. D. Searle & Co. | α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]-acetamides |
CA1213586A (en) * | 1982-09-27 | 1986-11-04 | Gilbert W. Adelstein | Substituted pyridopyridiminones |
US4560754A (en) * | 1983-09-14 | 1985-12-24 | G. D. Searle & Co. | Substituted 5-phenyl-5-(aminoalkyl)-1,3-diazabicyclo[4.4.0]decan-4-ones and 5-phenyl-5-(aminoalkyl)-1,3-diazabicyclo[4.4.0]dec-2-en-4-ones |
DE3344429A1 (de) * | 1983-12-08 | 1985-06-20 | Wacker-Chemie GmbH, 8000 München | Verfahren zur herstellung von 2-isopropyl-4-methyl-6-hydroxypyrimidin |
IL76583A (en) * | 1984-10-19 | 1988-08-31 | Robins Co Inc A H | 1-(aminoalkyl)-alpha'alpha-diaryl pyrrolidinyl,piperidino and homopiperidino acetamides and acetonitriles and pharmaceutical compositions containing them |
US4680295A (en) * | 1986-02-03 | 1987-07-14 | G. D. Searle & Co. | Octahydropyrido[1,2-c]pyrimidinones and hexahydropyrido[1,2-c]pyrimidinediones |
-
1985
- 1985-09-19 US US06/777,661 patent/US4791199A/en not_active Expired - Fee Related
-
1986
- 1986-09-17 EP EP86112839A patent/EP0215477A1/en not_active Withdrawn
- 1986-09-17 AU AU62770/86A patent/AU589447B2/en not_active Ceased
- 1986-09-17 ES ES8601961A patent/ES2002161A6/es not_active Expired
- 1986-09-18 JP JP61220827A patent/JPS6270375A/ja active Pending
- 1986-09-18 ZA ZA867114A patent/ZA867114B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
US4791199A (en) | 1988-12-13 |
AU589447B2 (en) | 1989-10-12 |
EP0215477A1 (en) | 1987-03-25 |
AU6277086A (en) | 1987-03-26 |
ZA867114B (en) | 1987-11-25 |
JPS6270375A (ja) | 1987-03-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20001102 |