DE3542744C1 - Poroeses Hydroxylapatit-Material - Google Patents

Poroeses Hydroxylapatit-Material

Info

Publication number
DE3542744C1
DE3542744C1 DE3542744A DE3542744A DE3542744C1 DE 3542744 C1 DE3542744 C1 DE 3542744C1 DE 3542744 A DE3542744 A DE 3542744A DE 3542744 A DE3542744 A DE 3542744A DE 3542744 C1 DE3542744 C1 DE 3542744C1
Authority
DE
Germany
Prior art keywords
pct
porous hydroxyapatite
hydroxyapatite
porous
bone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3542744A
Other languages
German (de)
English (en)
Inventor
Rolf Prof Dr Dr Ewers
Christian Dr Dr Kasperk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ewers Rolf Prof Drdr 2300 Kiel De
Original Assignee
Ewers Rolf Prof Drdr 2300 Kiel De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE3542744A priority Critical patent/DE3542744C1/de
Application filed by Ewers Rolf Prof Drdr 2300 Kiel De filed Critical Ewers Rolf Prof Drdr 2300 Kiel De
Priority to DE8686116817T priority patent/DE3669829D1/de
Priority to EP86116817A priority patent/EP0230570B1/de
Priority to ES86116817T priority patent/ES2014976B3/es
Priority to US07/095,066 priority patent/US4770860A/en
Priority to CA000524437A priority patent/CA1276430C/en
Priority to JP62500225A priority patent/JPS63500778A/ja
Priority to PCT/EP1986/000702 priority patent/WO1987003491A1/de
Priority to AU67356/87A priority patent/AU583443B2/en
Priority to AT86116817T priority patent/ATE51346T1/de
Application granted granted Critical
Publication of DE3542744C1 publication Critical patent/DE3542744C1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/70—Preparations for dentistry comprising inorganic additives
    • A61K6/71—Fillers
    • A61K6/74—Fillers comprising phosphorus-containing compounds
    • A61K6/75—Apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/849—Preparations for artificial teeth, for filling teeth or for capping teeth comprising inorganic cements
    • A61K6/858—Calcium sulfates, e.g, gypsum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A61L27/365—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Zoology (AREA)
  • Materials For Medical Uses (AREA)
  • Dental Preparations (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cultivation Of Seaweed (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Heat Treatment Of Steel (AREA)
  • Heat Treatment Of Sheet Steel (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Artificial Fish Reefs (AREA)
DE3542744A 1985-12-03 1985-12-03 Poroeses Hydroxylapatit-Material Expired DE3542744C1 (de)

Priority Applications (10)

Application Number Priority Date Filing Date Title
DE3542744A DE3542744C1 (de) 1985-12-03 1985-12-03 Poroeses Hydroxylapatit-Material
EP86116817A EP0230570B1 (de) 1985-12-03 1986-12-03 Poröses Hydroxylapatit-Material
ES86116817T ES2014976B3 (es) 1985-12-03 1986-12-03 Material hidroxilapatita poroso
US07/095,066 US4770860A (en) 1985-12-03 1986-12-03 Porous hydroxyl apatite material
DE8686116817T DE3669829D1 (de) 1985-12-03 1986-12-03 Poroeses hydroxylapatit-material.
CA000524437A CA1276430C (en) 1985-12-03 1986-12-03 Porous hydroxyl apatite material
JP62500225A JPS63500778A (ja) 1985-12-03 1986-12-03 多孔質ヒドロキシル燐灰石材料
PCT/EP1986/000702 WO1987003491A1 (fr) 1985-12-03 1986-12-03 Matiere poreuse constituee d'hydroxylapatite
AU67356/87A AU583443B2 (en) 1985-12-03 1986-12-03 Porous hydroxyl apatite derived from lime-encrusting algae
AT86116817T ATE51346T1 (de) 1985-12-03 1986-12-03 Poroeses hydroxylapatit-material.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3542744A DE3542744C1 (de) 1985-12-03 1985-12-03 Poroeses Hydroxylapatit-Material

Publications (1)

Publication Number Publication Date
DE3542744C1 true DE3542744C1 (de) 1987-05-27

Family

ID=6287503

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3542744A Expired DE3542744C1 (de) 1985-12-03 1985-12-03 Poroeses Hydroxylapatit-Material
DE8686116817T Expired - Lifetime DE3669829D1 (de) 1985-12-03 1986-12-03 Poroeses hydroxylapatit-material.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8686116817T Expired - Lifetime DE3669829D1 (de) 1985-12-03 1986-12-03 Poroeses hydroxylapatit-material.

Country Status (9)

Country Link
US (1) US4770860A (enExample)
EP (1) EP0230570B1 (enExample)
JP (1) JPS63500778A (enExample)
AT (1) ATE51346T1 (enExample)
AU (1) AU583443B2 (enExample)
CA (1) CA1276430C (enExample)
DE (2) DE3542744C1 (enExample)
ES (1) ES2014976B3 (enExample)
WO (1) WO1987003491A1 (enExample)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0284074A1 (de) * 1987-03-26 1988-09-28 Rolf Prof. Dr. Dr. Ewers Verfahren zur Herstellung eines Hydroxylapatitmaterials
DE19543110A1 (de) * 1995-11-18 1997-06-12 Guy Florian Draenert Steriles Knochenmaterial nativen Ursprungs für die Transplantation und Verfahren zur Hitzesterilisierung des Knochenmaterials
EP0650374B1 (fr) * 1993-05-13 2000-07-26 Bio Holdings International Limited Utilisation d'un materiau poreux a base de carbonate de calcium comme support pour un facteur de croissance dans la preparation d'un implant bioresorbable
DE19950114A1 (de) * 1999-10-18 2001-04-26 Jordanova Spassova Margarita Knochenersatzmaterial und Vorstufen hierfür
WO2001028919A1 (de) * 1999-10-18 2001-04-26 Spassova, Else Tricalciumphosphat-haltiges hydroxylapatit-material mit mikroporöser struktur
US6881227B2 (en) 1999-11-30 2005-04-19 Margarita Jordanova-Spassova Hydroxylapatite material containing tricalcium phosphate with microporous structure
CN101954122A (zh) * 2010-09-13 2011-01-26 陕西瑞盛生物科技有限公司 具有预塑性天然骨修复材料的制备方法

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE108319T1 (de) * 1987-12-23 1994-07-15 Herbst Bremer Goldschlaegerei Zahnfüllungsmaterial.
FR2637502A1 (fr) * 1988-10-12 1990-04-13 Duroselle Patrick Materiau de xenogreffe osseuse et procede d'obtention
US4976736A (en) * 1989-04-28 1990-12-11 Interpore International Coated biomaterials and methods for making same
FR2647334A1 (fr) * 1989-05-23 1990-11-30 Cazprasse Serge Produits de remplacement de structures osseuses et radiculo-dentaires en nacre
FR2705235B1 (fr) * 1993-05-13 1995-07-13 Inoteb Utilisation de particules d'un sel de calcium biocompatible et biorésorbable comme ingrédient actif dans la préparation d'un médicament destiné au traitement local des maladies déminéralisantes de l'os.
BE1007549A3 (nl) † 1993-09-21 1995-08-01 Beckers Louis Francois Charles Implantaat.
US5668203A (en) * 1995-06-07 1997-09-16 Xerox Corporation Elastomeric articles containing haloceramer compositions
BG101544A (en) * 1997-05-30 1998-11-30 Медицински Университет-Ректорат Method for the preparation of biologically active coatings over titanium osteal implants
DE19723287A1 (de) * 1997-06-04 1998-12-10 Castolin Sa Implantat zum Einsatz bei Lebewesen, Verfahren zur Herstellung des Implantats sowie dessen Verwendung
WO1999019259A1 (en) * 1997-10-15 1999-04-22 Coral Biotech Kabushiki Kaisha Weathered hermatypic coral material
RU2168998C1 (ru) * 2000-02-14 2001-06-20 Волова Лариса Теодоровна Способ получения аллогенного гидроксилапатита
US6630153B2 (en) * 2001-02-23 2003-10-07 Smith & Nephew, Inc. Manufacture of bone graft substitutes
WO2004011053A1 (en) 2002-07-31 2004-02-05 Dentsply International Inc. Bone repair putty comprising porous particulate and carrier gel
US8876532B2 (en) 2002-07-31 2014-11-04 Dentsply International Inc. Bone repair putty
WO2006062518A2 (en) 2004-12-08 2006-06-15 Interpore Spine Ltd. Continuous phase composite for musculoskeletal repair
US20070038303A1 (en) * 2006-08-15 2007-02-15 Ebi, L.P. Foot/ankle implant and associated method
US8535357B2 (en) 2004-12-09 2013-09-17 Biomet Sports Medicine, Llc Continuous phase compositions for ACL repair
DE102005060761B4 (de) * 2005-12-16 2007-10-25 Alexakis, Antonis, Dr. med. dent. Formteil zur Neubildung von Knochenmaterial
JP5053624B2 (ja) * 2006-11-18 2012-10-17 学校法人東京歯科大学 歯質強化剤及びその製造方法
DE102007050440A1 (de) * 2007-10-18 2009-04-23 Alexakis, Antonis, Dr. med. dent. Beschichtetes Granulat zur Neubildung von Knochenmaterial
DE102011119909A1 (de) * 2011-12-01 2013-06-06 Antonis Alexakis Regenerations Hilfe für Knochendefekte
PL3777904T3 (pl) 2019-08-16 2022-08-22 Universität Heidelberg Osteotropowy substytut kości
EP4574180A1 (de) 2023-12-19 2025-06-25 Andreas Haas Modifiziertes knochenersatzmaterial

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929971A (en) * 1973-03-30 1975-12-30 Research Corp Porous biomaterials and method of making same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2067538A (en) * 1934-01-05 1937-01-12 Walter H Macintire Process for making double or treble (calcium) superphosphate
US2053266A (en) * 1934-05-21 1936-09-08 Tennessee Valley Authority Manufacture of calcium phosphates
US2043238A (en) * 1934-07-02 1936-06-09 Tennessee Valley Authority Manufacture of di-calcium phosphate
US2143025A (en) * 1936-03-02 1939-01-10 Roger H Newton Making monocalcium phosphate
DE1206293B (de) * 1960-01-16 1965-12-02 Knapsack Ag Verfahren zur Herstellung eines im wesentlichen aus Dicalciumphosphat bestehenden Mineralstoffbeifutters
AT352867B (de) * 1976-05-12 1979-10-10 Battelle Institut E V Knochenersatz-knochenverbund-oder prothesen- verankerungswerkstoff und verfahren zu seiner herstellung
CH643732A5 (en) * 1978-01-01 1984-06-29 Scheicher Hans Aid for covering and/or filling bone defects and process for the production thereof
FR2460710A1 (fr) * 1979-04-02 1981-01-30 Basset Francois Produit absorbant industriel contenant un produit vegetal
FR2460657A1 (fr) * 1979-07-12 1981-01-30 Anvar Implant biodegradable utilisable comme piece de prothese osseuse

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929971A (en) * 1973-03-30 1975-12-30 Research Corp Porous biomaterials and method of making same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DE-B.: Schumann, Walter: Steine und Mineralien, BLV-Verlagsgemeinschaft 1982 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0284074A1 (de) * 1987-03-26 1988-09-28 Rolf Prof. Dr. Dr. Ewers Verfahren zur Herstellung eines Hydroxylapatitmaterials
EP0650374B1 (fr) * 1993-05-13 2000-07-26 Bio Holdings International Limited Utilisation d'un materiau poreux a base de carbonate de calcium comme support pour un facteur de croissance dans la preparation d'un implant bioresorbable
DE19543110A1 (de) * 1995-11-18 1997-06-12 Guy Florian Draenert Steriles Knochenmaterial nativen Ursprungs für die Transplantation und Verfahren zur Hitzesterilisierung des Knochenmaterials
DE19543110C2 (de) * 1995-11-18 1998-05-28 Guy Florian Draenert Steriles Knochenmaterial nativen Ursprungs für die Transplantation und Verfahren zur Hitzesterilisierung des Knochenmaterials
DE19950114A1 (de) * 1999-10-18 2001-04-26 Jordanova Spassova Margarita Knochenersatzmaterial und Vorstufen hierfür
WO2001028919A1 (de) * 1999-10-18 2001-04-26 Spassova, Else Tricalciumphosphat-haltiges hydroxylapatit-material mit mikroporöser struktur
WO2001028920A1 (de) * 1999-10-18 2001-04-26 Spassova, Else Knochenersatzmaterial und vorstufen hierfür
DE19950113A1 (de) * 1999-10-18 2001-05-03 Jordanova Spassova Margarita Tricalciumphosphat-haltiges Hydroxylapatit-Material
US6881227B2 (en) 1999-11-30 2005-04-19 Margarita Jordanova-Spassova Hydroxylapatite material containing tricalcium phosphate with microporous structure
CN101954122A (zh) * 2010-09-13 2011-01-26 陕西瑞盛生物科技有限公司 具有预塑性天然骨修复材料的制备方法

Also Published As

Publication number Publication date
DE3669829D1 (de) 1990-05-03
ATE51346T1 (de) 1990-04-15
WO1987003491A1 (fr) 1987-06-18
EP0230570B1 (de) 1990-03-28
US4770860A (en) 1988-09-13
AU583443B2 (en) 1989-04-27
JPH0346146B2 (enExample) 1991-07-15
ES2014976B3 (es) 1990-08-01
CA1276430C (en) 1990-11-20
EP0230570A1 (de) 1987-08-05
AU6735687A (en) 1987-06-30
JPS63500778A (ja) 1988-03-24

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D1 Grant (no unexamined application published) patent law 81
8364 No opposition during term of opposition