DE3504724C2 - Verfahren zur Einkapselung eines einzuhüllenden Materials - Google Patents

Verfahren zur Einkapselung eines einzuhüllenden Materials

Info

Publication number
DE3504724C2
DE3504724C2 DE3504724A DE3504724A DE3504724C2 DE 3504724 C2 DE3504724 C2 DE 3504724C2 DE 3504724 A DE3504724 A DE 3504724A DE 3504724 A DE3504724 A DE 3504724A DE 3504724 C2 DE3504724 C2 DE 3504724C2
Authority
DE
Germany
Prior art keywords
membrane
process according
capsules
gel
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3504724A
Other languages
German (de)
English (en)
Other versions
DE3504724A1 (de
Inventor
Ann W. Newton Center Mass. Shyr
Wen-Ghih Lexington Mass. Tsang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Biotech Inc
Original Assignee
Damon Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Damon Biotech Inc filed Critical Damon Biotech Inc
Publication of DE3504724A1 publication Critical patent/DE3504724A1/de
Application granted granted Critical
Publication of DE3504724C2 publication Critical patent/DE3504724C2/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012—Cell encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/74—Alginate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
DE3504724A 1984-02-13 1985-02-12 Verfahren zur Einkapselung eines einzuhüllenden Materials Expired DE3504724C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/579,494 US4663286A (en) 1984-02-13 1984-02-13 Encapsulation of materials

Publications (2)

Publication Number Publication Date
DE3504724A1 DE3504724A1 (de) 1985-09-05
DE3504724C2 true DE3504724C2 (de) 1987-03-26

Family

ID=24317126

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3504724A Expired DE3504724C2 (de) 1984-02-13 1985-02-12 Verfahren zur Einkapselung eines einzuhüllenden Materials

Country Status (14)

Country Link
US (1) US4663286A (cg-RX-API-DMAC10.html)
JP (1) JPS60190229A (cg-RX-API-DMAC10.html)
AU (1) AU572609B2 (cg-RX-API-DMAC10.html)
BE (1) BE901704A (cg-RX-API-DMAC10.html)
CA (1) CA1238273A (cg-RX-API-DMAC10.html)
CH (1) CH665137A5 (cg-RX-API-DMAC10.html)
DE (1) DE3504724C2 (cg-RX-API-DMAC10.html)
DK (1) DK65285A (cg-RX-API-DMAC10.html)
FR (1) FR2559502B1 (cg-RX-API-DMAC10.html)
GB (1) GB2153780B (cg-RX-API-DMAC10.html)
IT (1) IT1184885B (cg-RX-API-DMAC10.html)
NL (1) NL8500352A (cg-RX-API-DMAC10.html)
NO (1) NO850535L (cg-RX-API-DMAC10.html)
SE (1) SE8500623L (cg-RX-API-DMAC10.html)

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US5389532A (en) * 1988-07-07 1995-02-14 Champagne Moet & Chandon Process of producing a dehydrated polysaccharide gel containing microorganisms for preparing fermented drinks
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Also Published As

Publication number Publication date
SE8500623L (sv) 1985-08-14
CH665137A5 (de) 1988-04-29
GB2153780B (en) 1987-10-21
GB2153780A (en) 1985-08-29
DK65285A (da) 1985-08-14
FR2559502B1 (fr) 1988-08-26
IT8567142A0 (it) 1985-02-12
IT1184885B (it) 1987-10-28
DK65285D0 (da) 1985-02-12
CA1238273A (en) 1988-06-21
IT8567142A1 (it) 1986-08-12
SE8500623D0 (sv) 1985-02-12
DE3504724A1 (de) 1985-09-05
US4663286A (en) 1987-05-05
GB8503247D0 (en) 1985-03-13
BE901704A (fr) 1985-05-29
NL8500352A (nl) 1985-09-02
JPS60190229A (ja) 1985-09-27
FR2559502A1 (fr) 1985-08-16
AU572609B2 (en) 1988-05-12
NO850535L (no) 1985-08-14
JPH0150454B2 (cg-RX-API-DMAC10.html) 1989-10-30
AU3857285A (en) 1985-08-22

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