BE901704A - Procede d'encapsulation, notamment de cellules, dans des membranes semi-permeables. - Google Patents
Procede d'encapsulation, notamment de cellules, dans des membranes semi-permeables.Info
- Publication number
- BE901704A BE901704A BE0/214493A BE214493A BE901704A BE 901704 A BE901704 A BE 901704A BE 0/214493 A BE0/214493 A BE 0/214493A BE 214493 A BE214493 A BE 214493A BE 901704 A BE901704 A BE 901704A
- Authority
- BE
- Belgium
- Prior art keywords
- semi
- gelled masses
- encapsulation process
- permeable membranes
- aqueous solution
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
- B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/20—After-treatment of capsule walls, e.g. hardening
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0012—Cell encapsulation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
- C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/74—Alginate
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Treatments Of Macromolecular Shaped Articles (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
Procédé qui comprend la gélification d'un polymère polyanionique hydrosoluble contenant une matière d'ame dans une solution aqueuse contenant des cations polyvalents, afin que des masses gélifiées séparées se forment, puis l'expansion de ces masses gélifiées dans une solution aqueuse qui retire une partie des cations polyvalents et assure une hydratation des masses gélifiées, et la formation d'une membrane autour des masses gélifiées, par réaction entre des groupes anioniques du polymère polyanionique et des groupes cationiques d'un polymère polycationique dont la masse moléculaire dépasse 3000 daltons.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/579,494 US4663286A (en) | 1984-02-13 | 1984-02-13 | Encapsulation of materials |
Publications (1)
Publication Number | Publication Date |
---|---|
BE901704A true BE901704A (fr) | 1985-05-29 |
Family
ID=24317126
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE0/214493A BE901704A (fr) | 1984-02-13 | 1985-02-11 | Procede d'encapsulation, notamment de cellules, dans des membranes semi-permeables. |
Country Status (14)
Country | Link |
---|---|
US (1) | US4663286A (fr) |
JP (1) | JPS60190229A (fr) |
AU (1) | AU572609B2 (fr) |
BE (1) | BE901704A (fr) |
CA (1) | CA1238273A (fr) |
CH (1) | CH665137A5 (fr) |
DE (1) | DE3504724A1 (fr) |
DK (1) | DK65285A (fr) |
FR (1) | FR2559502B1 (fr) |
GB (1) | GB2153780B (fr) |
IT (1) | IT1184885B (fr) |
NL (1) | NL8500352A (fr) |
NO (1) | NO850535L (fr) |
SE (1) | SE8500623L (fr) |
Families Citing this family (96)
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US5605835A (en) * | 1988-05-23 | 1997-02-25 | Regents Of The University Of Minnesota | Bioreactor device with application as a bioartificial liver |
US5389532A (en) * | 1988-07-07 | 1995-02-14 | Champagne Moet & Chandon | Process of producing a dehydrated polysaccharide gel containing microorganisms for preparing fermented drinks |
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US5190041A (en) * | 1989-08-11 | 1993-03-02 | Palti Yoram Prof | System for monitoring and controlling blood glucose |
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US5227298A (en) * | 1990-08-17 | 1993-07-13 | The Trustees Of Columbia University In The City Of New York | Method for microencapuslation of cells or tissue |
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US5380536A (en) | 1990-10-15 | 1995-01-10 | The Board Of Regents, The University Of Texas System | Biocompatible microcapsules |
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US4407957A (en) * | 1981-03-13 | 1983-10-04 | Damon Corporation | Reversible microencapsulation of a core material |
US4439488A (en) * | 1982-02-26 | 1984-03-27 | The United States Of America As Represented By The Secretary Of Agriculture | Encapsulation by entrapment within polyhydroxy polymer borates |
US4582799A (en) * | 1983-04-15 | 1986-04-15 | Damon Biotech, Inc. | Process for recovering nonsecreted substances produced by cells |
-
1984
- 1984-02-13 US US06/579,494 patent/US4663286A/en not_active Expired - Fee Related
-
1985
- 1985-02-07 NL NL8500352A patent/NL8500352A/nl not_active Application Discontinuation
- 1985-02-07 CA CA000473751A patent/CA1238273A/fr not_active Expired
- 1985-02-08 AU AU38572/85A patent/AU572609B2/en not_active Ceased
- 1985-02-08 GB GB08503247A patent/GB2153780B/en not_active Expired
- 1985-02-11 BE BE0/214493A patent/BE901704A/fr not_active IP Right Cessation
- 1985-02-12 FR FR8501965A patent/FR2559502B1/fr not_active Expired
- 1985-02-12 NO NO850535A patent/NO850535L/no unknown
- 1985-02-12 DE DE19853504724 patent/DE3504724A1/de active Granted
- 1985-02-12 DK DK65285A patent/DK65285A/da not_active Application Discontinuation
- 1985-02-12 IT IT67142/85A patent/IT1184885B/it active
- 1985-02-12 SE SE8500623A patent/SE8500623L/ not_active Application Discontinuation
- 1985-02-12 CH CH642/85A patent/CH665137A5/de not_active IP Right Cessation
- 1985-02-13 JP JP60026135A patent/JPS60190229A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
CH665137A5 (de) | 1988-04-29 |
GB2153780A (en) | 1985-08-29 |
IT8567142A0 (it) | 1985-02-12 |
IT1184885B (it) | 1987-10-28 |
FR2559502A1 (fr) | 1985-08-16 |
DE3504724A1 (de) | 1985-09-05 |
DK65285D0 (da) | 1985-02-12 |
CA1238273A (fr) | 1988-06-21 |
JPS60190229A (ja) | 1985-09-27 |
AU3857285A (en) | 1985-08-22 |
FR2559502B1 (fr) | 1988-08-26 |
DE3504724C2 (fr) | 1987-03-26 |
AU572609B2 (en) | 1988-05-12 |
DK65285A (da) | 1985-08-14 |
GB2153780B (en) | 1987-10-21 |
IT8567142A1 (it) | 1986-08-12 |
JPH0150454B2 (fr) | 1989-10-30 |
US4663286A (en) | 1987-05-05 |
GB8503247D0 (en) | 1985-03-13 |
NL8500352A (nl) | 1985-09-02 |
NO850535L (no) | 1985-08-14 |
SE8500623D0 (sv) | 1985-02-12 |
SE8500623L (sv) | 1985-08-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: DAMON BIOTECH INC. Effective date: 19980228 |