DE3486009D1 - 5-pyridyl-1,3-thiazol-derivate, ihre herstellung und anwendung. - Google Patents

5-pyridyl-1,3-thiazol-derivate, ihre herstellung und anwendung.

Info

Publication number
DE3486009D1
DE3486009D1 DE8484305789T DE3486009T DE3486009D1 DE 3486009 D1 DE3486009 D1 DE 3486009D1 DE 8484305789 T DE8484305789 T DE 8484305789T DE 3486009 T DE3486009 T DE 3486009T DE 3486009 D1 DE3486009 D1 DE 3486009D1
Authority
DE
Germany
Prior art keywords
pyridyl
production
thiazol derivatives
thiazol
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8484305789T
Other languages
English (en)
Other versions
DE3486009T2 (de
Inventor
Shinji Terao
Yoshitaka Maki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP16704283A external-priority patent/JPS6058981A/ja
Priority claimed from JP7781984A external-priority patent/JPS6110580A/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DE3486009D1 publication Critical patent/DE3486009D1/de
Application granted granted Critical
Publication of DE3486009T2 publication Critical patent/DE3486009T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8484305789T 1983-09-09 1984-08-23 5-pyridyl-1,3-thiazol-derivate, ihre herstellung und anwendung. Expired - Fee Related DE3486009T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP16704283A JPS6058981A (ja) 1983-09-09 1983-09-09 ５−ピリジル−１，３−チアゾ−ル誘導体，その製造法およびそれを含んでなる医薬組成物
JP7781984A JPS6110580A (ja) 1984-04-17 1984-04-17 ５−ピリジル−１，３−チアゾ−ル誘導体，その製造法およびそれを含んでなる医薬組成物

Publications (2)

Publication Number Publication Date
DE3486009D1 true DE3486009D1 (de) 1993-01-28
DE3486009T2 DE3486009T2 (de) 1993-04-15

Family

ID=26418876

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484305789T Expired - Fee Related DE3486009T2 (de) 1983-09-09 1984-08-23 5-pyridyl-1,3-thiazol-derivate, ihre herstellung und anwendung.

Country Status (7)

Country Link
US (1) US4612321A (de)
EP (1) EP0149884B1 (de)
KR (1) KR910004430B1 (de)
AU (1) AU567754B2 (de)
CA (1) CA1255663A (de)
DE (1) DE3486009T2 (de)
HU (1) HU201753B (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649146A (en) * 1983-01-31 1987-03-10 Fujisawa Pharmaceutical Co., Ltd. Thiazole derivatives and pharmaceutical composition comprising the same
US4697012A (en) * 1984-07-25 1987-09-29 Merck & Co., Inc. Morpholino pyridyl thiazole compound
US4725606A (en) * 1984-07-25 1988-02-16 Merck & Co., Inc. 2-benzyl-4-(4-pyridyl)thiazoles and derivatives thereof as immunoregulants and compositions
DE3669160D1 (en) * 1985-03-27 1990-04-05 Zenyaku Kogyo Kk Thiazolderivate.
US4650805A (en) * 1985-12-02 1987-03-17 Warner-Lambert Company 4-(1,2,5,6-Tetrahydro-1-alkyl-3-pyridinyl)-2-thiazolamines and 4-(hexahydro-1-alkyl-3-pyridinyl)-2-thiazolamines having anti-psychotic activity
USRE34242E (en) * 1986-04-29 1993-05-04 Akzo N.V. Amino-oxazole compounds having dopaminergic activity
GB8610432D0 (en) * 1986-04-29 1986-06-04 Akzo Nv Amino-thiazole & oxazole derivatives
FR2612189B1 (fr) * 1987-03-13 1989-06-23 Roussel Uclaf Nouveaux derives de la pyridine, leur procede de preparation et les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions les renfermant
FR2656610B1 (fr) * 1989-12-29 1992-05-07 Sanofi Sa Derives d'amino-2 phenyl-4 thiazole, leur procede de preparation et leur application therapeutique.
GB9027613D0 (en) * 1990-12-20 1991-02-13 Ici Plc Fungicides
US5493024A (en) * 1991-04-11 1996-02-20 Dowelanco 3,4,N-trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insectioides
DE4124942A1 (de) * 1991-07-27 1993-01-28 Thomae Gmbh Dr K 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB9201692D0 (en) * 1992-01-27 1992-03-11 Smithkline Beecham Intercredit Compounds
WO1996003392A1 (en) * 1994-07-27 1996-02-08 G.D. Searle & Co. Substituted thiazoles for the treatment of inflammation
US5977125A (en) 1994-10-31 1999-11-02 Eisai Co., Ltd. Mono-or polyenic carboxylic acid derivatives
JP2636819B2 (ja) 1994-12-20 1997-07-30 日本たばこ産業株式会社 オキサゾール系複素環式芳香族化合物
US6388076B1 (en) * 1995-06-19 2002-05-14 Ontogen Corporation Protein tyrosine phosphatase-inhibiting compounds
JP3964478B2 (ja) 1995-06-30 2007-08-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 ヘテロ環含有カルボン酸誘導体及びそれを含有する医薬
CA2302417A1 (en) * 1997-10-27 1999-05-06 Takeda Chemical Industries, Ltd. Adenosine a3 receptor antagonists
WO1999064418A1 (en) * 1998-06-05 1999-12-16 Novartis Ag Aryl pyridinyl thiazoles
HUP0203766A3 (en) 1999-04-23 2008-01-28 Takeda Pharmaceutical 5-pyridyl-1,3-azole compounds, process for producing the same and use thereof and pharmaceutical compositions containing them
WO2001010865A1 (fr) * 1999-08-06 2001-02-15 Takeda Chemical Industries, Ltd. INHIBITEURS DE p38MAP KINASE
EP1268474A2 (de) * 2000-03-30 2003-01-02 Takeda Chemical Industries, Ltd. Substituierte 1,3-thiazol-verbindungen, ihre herstellung und verwendung
EP1348706B1 (de) 2000-12-08 2009-08-19 Takeda Pharmaceutical Company Limited Substituierte thiazolderivate mit 3-pyridylgruppen, verfahren zu deren herstellung und deren verwendung
EP1364949A4 (de) * 2001-02-02 2005-11-23 Takeda Pharmaceutical Jnk inhibitor
HUP0401748A3 (en) 2001-08-13 2011-03-28 Janssen Pharmaceutica Nv 2-amino-4,5-trisubstituted thiazolyl derivatives, process for their preparation and pharmaceutical compositions containing them
AP2005003261A0 (en) 2002-09-18 2005-03-31 Pfizer Prod Inc Novel oxazole and thiazole compounds as transforming growth factor (TGF) inhibitors.
CA2497971A1 (en) * 2002-09-18 2004-04-01 Pfizer Products Inc. Triazole derivatives as transforming growth factor (tgf) inhibitors
GB0326601D0 (en) * 2003-11-14 2003-12-17 Novartis Ag Organic compounds
CA2623813A1 (en) 2005-10-03 2007-04-12 Ono Pharmaceutical Co., Ltd. Nitrogen-containing heterocyclic compound and pharmaceutical application thereof
AU2012203026B2 (en) * 2008-03-21 2014-06-12 Novartis Ag Novel heterocyclic compounds and uses thereof
US8865732B2 (en) 2008-03-21 2014-10-21 Novartis Ag Heterocyclic compounds and uses thereof
TWI435874B (zh) * 2008-10-31 2014-05-01 Toray Industries 環己烷衍生物及其醫藥用途
KR20120096076A (ko) * 2009-12-17 2012-08-29 메르크 파텐트 게엠베하 스핑고신 키나아제 저해제
EP2731427A2 (de) 2011-07-15 2014-05-21 Basf Se Pestizidverfahren mit substituierten 3-pyridyl-thiazolverbindungen und derivaten zur bekämpfung von tierschädlingen i
US20150368236A1 (en) 2012-12-27 2015-12-24 Basf Se 2-(pyridin-3-yl)-5-hetaryl-thiazole compounds carrying an imine or imine-derived substituent for combating invertebrate pests
US9242969B2 (en) 2013-03-14 2016-01-26 Novartis Ag Biaryl amide compounds as kinase inhibitors
UY36294A (es) 2014-09-12 2016-04-29 Novartis Ag Compuestos y composiciones como inhibidores de quinasa

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1062245B (de) * 1957-10-17 1959-07-30 Ciba Geigy Verfahren zur Herstellung von 2-Amino-4-pyridyl-(2')-thiazol und seinen Salzen
GB1112128A (en) * 1965-12-22 1968-05-01 Bellon Labor Sa Roger New thiazolyl-diphenylmethane derivatives
CH506548A (de) * 1966-08-10 1971-04-30 Serono Ist Farm Verfahren zur Herstellung von 2-aminsubstituiertem 4,5-Diphenyl-Oxazol
US3578671A (en) * 1967-11-06 1971-05-11 Wyeth John & Brother Ltd Oxazoles
US3705153A (en) * 1969-05-14 1972-12-05 Sumitomo Chemical Co Novel thiazolyacetic acids and salts thereof
HU168776B (de) * 1973-11-09 1976-07-28
US4197306A (en) * 1977-06-30 1980-04-08 Uniroyal, Inc. Aryl-substituted thiazoles
US4528291A (en) * 1982-06-22 1985-07-09 Schering Corporation 2-(4'-Pyridinyl)-thiazole compounds and their use in increasing cardiac contractility
US4697012A (en) * 1984-07-25 1987-09-29 Merck & Co., Inc. Morpholino pyridyl thiazole compound

Also Published As

Publication number Publication date
EP0149884A3 (en) 1986-07-30
EP0149884B1 (de) 1992-12-16
KR850002472A (ko) 1985-05-13
HUT37424A (en) 1985-12-28
EP0149884A2 (de) 1985-07-31
AU567754B2 (en) 1987-12-03
AU3243384A (en) 1985-03-14
US4612321A (en) 1986-09-16
CA1255663A (en) 1989-06-13
DE3486009T2 (de) 1993-04-15
KR910004430B1 (ko) 1991-06-27
HU201753B (en) 1990-12-28

Similar Documents

Publication Publication Date Title
DE3486009D1 (de) 5-pyridyl-1,3-thiazol-derivate, ihre herstellung und anwendung.
ATE89560T1 (de) Makrolid-derivate, ihre herstellung und ihre verwendung.
DE3684948D1 (de) Imidderivate, ihre herstellung und anwendung.
DE3578418D1 (de) Chinonderivate, ihre herstellung und verwendung.
DE3788709T2 (de) Piperidin-Derivate, ihre Herstellung und Anwendung.
DE3777366D1 (de) 2,3-dihydro-cumaron-derivate, ihre herstellung und verwendung.
DE3587366D1 (de) Benzimidazol-derivate, ihre herstellung und verwendung.
DE69008454D1 (de) Nitrolsothiolderivate, ihre Herstellung und Verwendung.
DE68907559D1 (de) Sulfoniumsalze, ihre anwendung und ihre herstellung.
DE3668891D1 (de) Benzothiazolone, ihre herstellung und anwendung.
DE3879024T2 (de) Pyridinium-Derivate, ihre Herstellung und Verwendung.
DE68908313D1 (de) Klebverbaende, ihre herstellung und anwendung.
DE3777604D1 (de) Makrolid-verbindungen, ihre herstellung und ihre verwendung.
DE3784602D1 (de) Inonos-derivate, ihre herstellung und verwendung.
DE3773722D1 (de) Inosose-derivate und ihre herstellung.
ATE34392T1 (de) Imidazolinderivate, ihre herstellung und therapeutische verwendung.
DE68908389T2 (de) Amidofluoroverbindungen, ihre herstellung und ihre verwendung.
ATE40691T1 (de) Cephalosporinderivate, ihre herstellung und ihre verwendung.
ATE96142T1 (de) Triglyceridquartaerammonium-verbindungen, ihre herstellung und anwendung.
DE3879328D1 (de) Stannosilikate, ihre herstellung und verwendung.
DE3784778T2 (de) Cephemverbindungen, ihre herstellung und anwendung.
DE3770299D1 (de) 1,2,4-triazinonderivate, ihre herstellung und verwendung.
DE3381241D1 (de) 1-diorganocarbamoyl-polyalkylpiperidine und ihre herstellung.
ATE15895T1 (de) Pyridinderivate, ihre herstellung und ihre therapeutische anwendung.
DE3784893T2 (de) Benzothiazolone, ihre herstellung und ihre anwendung.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee