DE3382607D1 - Plasmide mit konditionalem unkontrolliertem replikationsverhalten. - Google Patents

Plasmide mit konditionalem unkontrolliertem replikationsverhalten.

Info

Publication number
DE3382607D1
DE3382607D1 DE8383305438T DE3382607T DE3382607D1 DE 3382607 D1 DE3382607 D1 DE 3382607D1 DE 8383305438 T DE8383305438 T DE 8383305438T DE 3382607 T DE3382607 T DE 3382607T DE 3382607 D1 DE3382607 D1 DE 3382607D1
Authority
DE
Germany
Prior art keywords
plasmide
uncontrolled replication
replication behavior
conditional
conditional uncontrolled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8383305438T
Other languages
English (en)
Other versions
DE3382607T2 (de
Inventor
Soren Molin
Janice Ann Light
Jens Erik Love Larsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharma AS
Original Assignee
Alfred Benzon AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfred Benzon AS filed Critical Alfred Benzon AS
Publication of DE3382607D1 publication Critical patent/DE3382607D1/de
Application granted granted Critical
Publication of DE3382607T2 publication Critical patent/DE3382607T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/68—Stabilisation of the vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/69—Increasing the copy number of the vector

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE19833382607 1982-09-16 1983-09-16 Plasmide mit konditionalem unkontrolliertem replikationsverhalten. Expired - Lifetime DE3382607T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK415182 1982-09-16
DK427082 1982-09-24

Publications (2)

Publication Number Publication Date
DE3382607D1 true DE3382607D1 (de) 1992-09-17
DE3382607T2 DE3382607T2 (de) 1993-03-11

Family

ID=26067368

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19833382607 Expired - Lifetime DE3382607T2 (de) 1982-09-16 1983-09-16 Plasmide mit konditionalem unkontrolliertem replikationsverhalten.
DE1983305438 Pending DE109150T1 (de) 1982-09-16 1983-09-16 Plasmide mit konditionalem unkontrolliertem replikationsverhalten.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE1983305438 Pending DE109150T1 (de) 1982-09-16 1983-09-16 Plasmide mit konditionalem unkontrolliertem replikationsverhalten.

Country Status (11)

Country Link
EP (1) EP0109150B1 (de)
JP (2) JPH0753111B2 (de)
AU (1) AU569043B2 (de)
CA (1) CA1313829C (de)
DE (2) DE3382607T2 (de)
FI (1) FI89941C (de)
HU (1) HU201116B (de)
IE (1) IE58059B1 (de)
IL (1) IL69741A (de)
NO (1) NO175488C (de)
WO (1) WO1984001171A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5702916A (en) * 1982-09-16 1997-12-30 Gx Biosystems A/S Biological Containment
US4710473A (en) * 1983-08-10 1987-12-01 Amgen, Inc. DNA plasmids
GB8407498D0 (en) * 1984-03-22 1984-05-02 Biogen Nv High copy number expression vectors
GB2166743B (en) * 1984-11-13 1989-01-05 Solvay Process for a thermo-inducible gene expression in gram positive bacteria and bacillus subtilis strains containing plasmids which induce such an expression
US5173418A (en) * 1985-05-10 1992-12-22 Benzon Pharma, A/S Production in Escherichia coli of extracellular Serratia spp. hydrolases
US4874703A (en) * 1985-08-26 1989-10-17 Eli Lilly And Company Expression vectors for use in E. coli
DE3750125T2 (de) * 1986-03-26 1994-10-27 Genexpress Aps Biologische eindämmung.
NZ225760A (en) * 1987-08-14 1991-02-26 Bio Technology General Corp Expression plasmids containing the deo promoter and bacterial hosts containing these plasmids
US5593860A (en) * 1987-08-14 1997-01-14 Bio-Technology General Corp. Expression plasmids containing the deo promoter, and bacterial hosts containing the plasmids
CA2057715A1 (en) * 1990-12-19 1992-06-20 Charles L. Hershberger Method for enhancing the structural stability of recombinant dna expression vectors
GB9215540D0 (en) * 1992-07-22 1992-09-02 Celltech Ltd Protein expression system
WO2000028048A1 (en) * 1998-11-09 2000-05-18 Genecare Development Aps Novel plasmids for use in medicine and method of producing same
US6991786B1 (en) * 2000-08-30 2006-01-31 Wisconsin Alumni Research Foundation Anti-microbial biotherapeutic agents: alternatives to conventional pharmaceutical antibiotics
US7758854B2 (en) 2001-08-30 2010-07-20 Wisconsin Alumni Research Foundation Anti-microbial agents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2759053A1 (de) * 1977-12-30 1979-07-12 Uhlin Verfahren zum herstellen von genprodukten von plasmid-dns
FI793884A (fi) * 1978-12-26 1980-06-27 Cetus Corp Stabila plasmider med stort kopieantal
CA1198067A (en) * 1981-02-27 1985-12-17 David H. Gelfand Stable high copy number plasmids
IL65775A (en) * 1981-05-18 1985-05-31 Genentech Inc Microbial hybrid promotors and plasmids and e.coli comprising them
DK410783D0 (da) * 1982-09-16 1983-09-09 Benzon A Salfred Fremgangsmade til stabilisering af plasmider
GB8308236D0 (en) * 1983-03-25 1983-05-05 Celltech Ltd Dna vectors

Also Published As

Publication number Publication date
HU201116B (en) 1990-09-28
IE58059B1 (en) 1993-06-30
FI841976A (fi) 1984-05-16
EP0109150A2 (de) 1984-05-23
AU569043B2 (en) 1988-01-21
WO1984001171A1 (en) 1984-03-29
DE3382607T2 (de) 1993-03-11
JPH0753111B2 (ja) 1995-06-07
JPH02238891A (ja) 1990-09-21
FI841976A0 (fi) 1984-05-16
DE109150T1 (de) 1984-10-25
IE832177L (en) 1984-03-16
NO841935L (no) 1984-05-15
AU1948783A (en) 1984-04-04
JPS59501532A (ja) 1984-08-30
CA1313829C (en) 1993-02-23
EP0109150A3 (en) 1985-10-09
FI89941B (fi) 1993-08-31
NO175488B (no) 1994-07-11
JP2604478B2 (ja) 1997-04-30
NO175488C (no) 1994-10-19
IL69741A (en) 1990-11-05
FI89941C (fi) 1993-12-10
EP0109150B1 (de) 1992-08-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NYCOMED DANMARK A/S, ROSKILDE, DK