DE3336748A1 - Verfahren zur abbildung des myokard von saeugetieren - Google Patents
Verfahren zur abbildung des myokard von saeugetierenInfo
- Publication number
- DE3336748A1 DE3336748A1 DE19833336748 DE3336748A DE3336748A1 DE 3336748 A1 DE3336748 A1 DE 3336748A1 DE 19833336748 DE19833336748 DE 19833336748 DE 3336748 A DE3336748 A DE 3336748A DE 3336748 A1 DE3336748 A1 DE 3336748A1
- Authority
- DE
- Germany
- Prior art keywords
- radiolabeled
- bromide
- halide
- compound according
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 241000124008 Mammalia Species 0.000 title claims 2
- 238000003384 imaging method Methods 0.000 title claims 2
- 238000000034 method Methods 0.000 title 1
- 150000004820 halides Chemical class 0.000 claims 9
- 150000001875 compounds Chemical class 0.000 claims 6
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 claims 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- -1 arsonium compound Chemical class 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- XYFCBTPGUUZFHI-UHFFFAOYSA-O phosphonium Chemical compound [PH4+] XYFCBTPGUUZFHI-UHFFFAOYSA-O 0.000 claims 2
- 125000001453 quaternary ammonium group Chemical group 0.000 claims 2
- LMQMZMZPRQQTFS-UHFFFAOYSA-M (2-iodophenyl)-triphenylphosphanium;bromide Chemical compound [Br-].IC1=CC=CC=C1[P+](C=1C=CC=CC=1)(C=1C=CC=CC=1)C1=CC=CC=C1 LMQMZMZPRQQTFS-UHFFFAOYSA-M 0.000 claims 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 229910052785 arsenic Inorganic materials 0.000 claims 1
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical compound [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 claims 1
- 150000005840 aryl radicals Chemical class 0.000 claims 1
- IOEPEYNGWPZHOG-UHFFFAOYSA-M benzyl-(2-bromophenyl)-diphenylphosphanium;bromide Chemical compound [Br-].BrC1=CC=CC=C1[P+](C=1C=CC=CC=1)(C=1C=CC=CC=1)CC1=CC=CC=C1 IOEPEYNGWPZHOG-UHFFFAOYSA-M 0.000 claims 1
- XBKZMRKXDQBGOQ-UHFFFAOYSA-M benzyl-(2-iodophenyl)-diphenylphosphanium;chloride Chemical compound [Cl-].IC1=CC=CC=C1[P+](C=1C=CC=CC=1)(C=1C=CC=CC=1)CC1=CC=CC=C1 XBKZMRKXDQBGOQ-UHFFFAOYSA-M 0.000 claims 1
- XKLGFIGRQOUCJC-UHFFFAOYSA-M benzyl-(iodomethyl)-methyl-phenylazanium;bromide Chemical compound [Br-].C=1C=CC=CC=1[N+](CI)(C)CC1=CC=CC=C1 XKLGFIGRQOUCJC-UHFFFAOYSA-M 0.000 claims 1
- HRZGUHKGMYCJJO-UHFFFAOYSA-M dibenzyl-(iodomethyl)-methylazanium;bromide Chemical group [Br-].C=1C=CC=CC=1C[N+](CI)(C)CC1=CC=CC=C1 HRZGUHKGMYCJJO-UHFFFAOYSA-M 0.000 claims 1
- VPARZUQTPKDGJW-UHFFFAOYSA-M iodomethyl(triphenyl)phosphanium;bromide Chemical group [Br-].C=1C=CC=CC=1[P+](C=1C=CC=CC=1)(CI)C1=CC=CC=C1 VPARZUQTPKDGJW-UHFFFAOYSA-M 0.000 claims 1
- 210000004165 myocardium Anatomy 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 229910052698 phosphorus Inorganic materials 0.000 claims 1
- 239000011574 phosphorus Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/433,871 US4446123A (en) | 1982-10-13 | 1982-10-13 | Process of radioimaging the myocardium of mammals utilizing radiolabeled lipophilic cations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3336748A1 true DE3336748A1 (de) | 1984-07-05 |
Family
ID=23721862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19833336748 Withdrawn DE3336748A1 (de) | 1982-10-13 | 1983-10-08 | Verfahren zur abbildung des myokard von saeugetieren |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4446123A (enExample) |
| JP (1) | JPS59139326A (enExample) |
| BE (1) | BE897968A (enExample) |
| CA (1) | CA1219207A (enExample) |
| DE (1) | DE3336748A1 (enExample) |
| FR (1) | FR2534576B1 (enExample) |
| GB (1) | GB2128191B (enExample) |
| IT (1) | IT1205396B (enExample) |
| LU (1) | LU85042A1 (enExample) |
| NL (1) | NL8303481A (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001271248A1 (en) * | 2000-04-28 | 2001-11-12 | Duke University | 18f-labeled choline analogs |
| US6548042B2 (en) * | 2000-08-07 | 2003-04-15 | Arstad Erik | Bis-phosphonate compounds |
| CN101838289A (zh) * | 2002-02-06 | 2010-09-22 | 约翰·霍普金斯大学 | 使用放射性同位素标示亲油性盐的用于线粒体机能障碍的非侵入性诊断显像技术 |
| AU2011203177B2 (en) * | 2004-02-24 | 2012-04-26 | The General Hospital Corporation | Catalytic radiofluorination |
| MXPA06009634A (es) * | 2004-02-24 | 2007-04-23 | Gen Hospital Corp | Radiofrecuencia catalitica. |
| US9017724B2 (en) | 2004-02-24 | 2015-04-28 | The General Hospital Corporation | Catalytic radiofluorination |
| US8257680B1 (en) | 2004-02-24 | 2012-09-04 | The General Hospital Corporation | Catalytic radiofluorination |
| US8388936B2 (en) * | 2008-02-22 | 2013-03-05 | Mcw Research Foundation, Inc. | In vivo mitochondrial labeling using positively-charged nitroxide enhanced and gadolinium chelate enhanced magnetic resonance imaging |
| US8450466B2 (en) | 2008-03-21 | 2013-05-28 | The General Hosptial Corporation | Compounds and compositions for the detection and treatment of Alzheimer's disease and related disorders |
| US9205156B2 (en) * | 2010-05-27 | 2015-12-08 | Hadasit Medical Research Services & Development Limited | Molecular imaging agents |
| JP6285164B2 (ja) * | 2013-12-05 | 2018-02-28 | デクセリアルズ株式会社 | 化合物、熱硬化性樹脂組成物、及び熱硬化性シート |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4107283A (en) * | 1976-07-19 | 1978-08-15 | New England Nuclear Corporation | Tracer for circulation determinations |
| JPS5572640A (en) * | 1978-11-27 | 1980-05-31 | Automob Antipollut & Saf Res Center | Air-fuel ratio control device |
| US4360511A (en) * | 1978-11-29 | 1982-11-23 | Medi-Physics, Inc. | Amines useful as brain imaging agents |
| JPS5932457B2 (ja) * | 1978-11-29 | 1984-08-09 | エフ・ホフマン−ラ・ロシユ・ウント・コンパニ−・アクチエンゲゼルシヤフト | 放射性ヨウ素化アミン |
| NL7900964A (nl) * | 1979-02-07 | 1980-08-11 | Byk Mallinckrodt Cil Bv | Nieuwe radioactief gemerkte aminen, werkwijze ter bereiding van de nieuwe verbindingen, alsmede diagnostische preparaten op basis van de nieuwe verbindingen. |
| US4387087A (en) * | 1980-04-18 | 1983-06-07 | Research Corporation | Cationic lipophilic complexes of 99m Tc and their use for myocardial and hepatobiliary imaging |
-
1982
- 1982-10-13 US US06/433,871 patent/US4446123A/en not_active Expired - Fee Related
-
1983
- 1983-10-08 DE DE19833336748 patent/DE3336748A1/de not_active Withdrawn
- 1983-10-10 NL NL8303481A patent/NL8303481A/nl not_active Application Discontinuation
- 1983-10-12 JP JP58189395A patent/JPS59139326A/ja active Granted
- 1983-10-12 LU LU85042A patent/LU85042A1/de unknown
- 1983-10-12 IT IT68048/83A patent/IT1205396B/it active
- 1983-10-12 GB GB08327249A patent/GB2128191B/en not_active Expired
- 1983-10-12 BE BE2/60226A patent/BE897968A/nl not_active IP Right Cessation
- 1983-10-13 CA CA000438933A patent/CA1219207A/en not_active Expired
- 1983-10-13 FR FR8316263A patent/FR2534576B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS59139326A (ja) | 1984-08-10 |
| FR2534576A1 (fr) | 1984-04-20 |
| JPS6217974B2 (enExample) | 1987-04-21 |
| FR2534576B1 (fr) | 1986-09-19 |
| GB2128191A (en) | 1984-04-26 |
| IT8368048A0 (it) | 1983-10-12 |
| US4446123A (en) | 1984-05-01 |
| GB8327249D0 (en) | 1983-11-16 |
| IT1205396B (it) | 1989-03-15 |
| NL8303481A (nl) | 1984-05-01 |
| LU85042A1 (de) | 1984-04-02 |
| GB2128191B (en) | 1986-05-08 |
| BE897968A (nl) | 1984-01-30 |
| CA1219207A (en) | 1987-03-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8139 | Disposal/non-payment of the annual fee |