DE3245665A1 - Verfahren zur herstellung permanenter tierischer und humaner zellinien und deren verwendung - Google Patents
Verfahren zur herstellung permanenter tierischer und humaner zellinien und deren verwendungInfo
- Publication number
- DE3245665A1 DE3245665A1 DE19823245665 DE3245665A DE3245665A1 DE 3245665 A1 DE3245665 A1 DE 3245665A1 DE 19823245665 DE19823245665 DE 19823245665 DE 3245665 A DE3245665 A DE 3245665A DE 3245665 A1 DE3245665 A1 DE 3245665A1
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- cells
- cell
- fusion
- human
- transformed
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- MHMNJMPURVTYEJ-UHFFFAOYSA-N fluorescein-5-isothiocyanate Chemical compound O1C(=O)C2=CC(N=C=S)=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 MHMNJMPURVTYEJ-UHFFFAOYSA-N 0.000 description 1
- 239000004052 folic acid antagonist Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
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- 230000005484 gravity Effects 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 210000003494 hepatocyte Anatomy 0.000 description 1
- 239000008241 heterogeneous mixture Substances 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 238000009396 hybridization Methods 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000002163 immunogen Effects 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 238000007912 intraperitoneal administration Methods 0.000 description 1
- 210000003292 kidney cell Anatomy 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 239000002523 lectin Substances 0.000 description 1
- 230000036210 malignancy Effects 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 235000010981 methylcellulose Nutrition 0.000 description 1
- 239000007758 minimum essential medium Substances 0.000 description 1
- 230000002297 mitogenic effect Effects 0.000 description 1
- 230000011278 mitosis Effects 0.000 description 1
- 230000000877 morphologic effect Effects 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 229940049954 penicillin Drugs 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 210000005105 peripheral blood lymphocyte Anatomy 0.000 description 1
- 210000003024 peritoneal macrophage Anatomy 0.000 description 1
- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- 210000004180 plasmocyte Anatomy 0.000 description 1
- 230000002062 proliferating effect Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- ATTPJEVJOXLCMF-UHFFFAOYSA-N propane-1,2,3-triol trihydrochloride Chemical compound Cl.Cl.Cl.OCC(O)CO ATTPJEVJOXLCMF-UHFFFAOYSA-N 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000003127 radioimmunoassay Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000026267 regulation of growth Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000001850 reproductive effect Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 230000003248 secreting effect Effects 0.000 description 1
- 238000010187 selection method Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
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- 230000004083 survival effect Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Priority Applications (20)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823245665 DE3245665A1 (de) | 1982-05-04 | 1982-12-09 | Verfahren zur herstellung permanenter tierischer und humaner zellinien und deren verwendung |
| GR71148A GR78532B (enExample) | 1982-05-04 | 1983-04-20 | |
| IE945/83A IE54881B1 (en) | 1982-05-04 | 1983-04-25 | Process for obtaining permanently culturable animal and human cell lines and the use thereof |
| YU00948/83A YU94883A (en) | 1982-05-04 | 1983-04-26 | Process for preparing animal and human cell lines |
| IL68515A IL68515A (en) | 1982-05-04 | 1983-04-28 | Process for obtaining permanently culturable cell lines,for obtaining homologous and/or heterologous cell products |
| EP83104243A EP0093436B1 (de) | 1982-05-04 | 1983-04-29 | Verfahren zur Herstellung permanenter tierischer und humaner Zellinien und deren Verwendung |
| AT83104243T ATE23361T1 (de) | 1982-05-04 | 1983-04-29 | Verfahren zur herstellung permanenter tierischer und humaner zellinien und deren verwendung. |
| DE8383104243T DE3367412D1 (en) | 1982-05-04 | 1983-04-29 | Process for preparing permanent animal and human cell lines, and their use |
| DD83250509A DD210708A5 (de) | 1982-05-04 | 1983-05-02 | Verfahren zur herstellung permanenter tierischer und humaner zellinien |
| AU14141/83A AU538828B2 (en) | 1982-05-04 | 1983-05-02 | Process for production of permanently culturable animal and human cell lines |
| SU833594155A SU1424744A3 (ru) | 1982-05-04 | 1983-05-03 | Способ получени перманентно растущих животных и человеческих клеток |
| FI831509A FI85282C (fi) | 1982-05-04 | 1983-05-03 | Foerfarande foer framstaellning av permanenta djur- och humancellinjer. |
| CA000427343A CA1201396A (en) | 1982-05-04 | 1983-05-03 | Process for the preparation of permanent animal and human cell lines and their use |
| HU831514A HU196456B (en) | 1982-05-04 | 1983-05-03 | Process for producing permanent animal and human cell lines |
| PT76629A PT76629B (de) | 1982-05-04 | 1983-05-03 | Verfahren zur herstellung permanenter tierischet und humaner zellinien und deren verwendung |
| ES522086A ES8402346A1 (es) | 1982-05-04 | 1983-05-04 | Procedimiento para la obtencion de lineas de celulas animales y humanas cultivables permanentemente. |
| DK199083A DK199083A (da) | 1982-05-04 | 1983-05-04 | Fremgangsmaade til fremstilling af permanente dyriske og humane cellelinier og deres anvendelse |
| JP60184369A JPH0753110B2 (ja) | 1982-05-04 | 1985-08-23 | 細胞産生物を取得する方法 |
| US07/590,602 US5114847A (en) | 1982-05-04 | 1990-09-25 | Process for the production of permanently culturable animal and human cell lines and the use thereof |
| LVP-93-462A LV11042B (en) | 1982-05-04 | 1993-06-02 | METHOD FOR PRODUCING OF PERMANENT ANIMAL AND HUMAN CELL LINES AND USE THEREOFL ACARICIDALLY ACTIVE TETRAZINE DERIVATIVESrylpirrole |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3216650 | 1982-05-04 | ||
| DE19823245665 DE3245665A1 (de) | 1982-05-04 | 1982-12-09 | Verfahren zur herstellung permanenter tierischer und humaner zellinien und deren verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3245665A1 true DE3245665A1 (de) | 1983-11-10 |
Family
ID=25801552
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19823245665 Withdrawn DE3245665A1 (de) | 1982-05-04 | 1982-12-09 | Verfahren zur herstellung permanenter tierischer und humaner zellinien und deren verwendung |
| DE8383104243T Expired DE3367412D1 (en) | 1982-05-04 | 1983-04-29 | Process for preparing permanent animal and human cell lines, and their use |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8383104243T Expired DE3367412D1 (en) | 1982-05-04 | 1983-04-29 | Process for preparing permanent animal and human cell lines, and their use |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5114847A (enExample) |
| EP (1) | EP0093436B1 (enExample) |
| JP (1) | JPH0753110B2 (enExample) |
| AU (1) | AU538828B2 (enExample) |
| CA (1) | CA1201396A (enExample) |
| DD (1) | DD210708A5 (enExample) |
| DE (2) | DE3245665A1 (enExample) |
| DK (1) | DK199083A (enExample) |
| ES (1) | ES8402346A1 (enExample) |
| FI (1) | FI85282C (enExample) |
| GR (1) | GR78532B (enExample) |
| HU (1) | HU196456B (enExample) |
| IE (1) | IE54881B1 (enExample) |
| IL (1) | IL68515A (enExample) |
| LV (1) | LV11042B (enExample) |
| PT (1) | PT76629B (enExample) |
| SU (1) | SU1424744A3 (enExample) |
| YU (1) | YU94883A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0209154A1 (de) | 1985-07-19 | 1987-01-21 | Roche Diagnostics GmbH | Verfahren und Reagenz zur spezifischen Bestimmung von Pankreas-alpha-Amylase |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL70686A (en) * | 1983-01-20 | 1988-07-31 | Suntory Ltd | Mutant tumor cell lines for use in the preparation of hybridomas and the hybridomas obtained therefrom |
| DE3342736A1 (de) * | 1983-11-25 | 1985-06-05 | Boehringer Mannheim Gmbh, 6800 Mannheim | Hybridoma-antikoerper |
| FR2565995B1 (fr) * | 1984-03-07 | 1987-10-23 | Centre Nat Rech Scient | Cellules hybrides productrices d'un polypeptide determine et obtenu a partir de cellules primaires naturellement capables d'exprimer ce polypeptide ou un polypeptide equivalent, procede pour l'obtention de ces cellules hybrides et application de celles-ci a la production dudit polypeptide |
| DE3420926A1 (de) * | 1984-06-05 | 1985-12-05 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und reagenz zur differenzierten bestimmung von isoenzymen der alkalischen phosphatase sowie hierzu geeigneter monoklonaler antikoerper |
| FR2581393B2 (fr) * | 1985-05-02 | 1989-07-21 | Grp Genie Genetique | Cellules hybrides productrices d'un antigene caracteristique du virus de l'hepatite b obtenu a partir d'hepatocytes et de cellules etablies de singe, procede pour l'obtention de ces cellules hybrides et application de celles-ci a la production de l'antigene susdit |
| EP0225916A1 (en) * | 1985-06-11 | 1987-06-24 | The Upjohn Company | Transfer of male sterility in carrots |
| EP0239102A3 (en) * | 1986-03-28 | 1989-07-12 | Tsuji, Kimiyoshi | Process for the formation of human-human hybridoma |
| DE3627326A1 (de) * | 1986-08-12 | 1988-02-18 | Boehringer Mannheim Gmbh | Immortalisierung durch dns-uebertragung |
| US5001065A (en) * | 1987-05-27 | 1991-03-19 | Cetus Corporation | Human cell line and triomas, antibodies, and transformants derived therefrom |
| US5175004A (en) * | 1988-12-27 | 1992-12-29 | Matsumura Kenneth N | Propagatable, new combinant cells for cellular replacement therapy |
| US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5981568A (en) | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5358844A (en) * | 1993-02-18 | 1994-10-25 | Brigham And Women's Hospital, Inc. | Preservation of blood platelets |
| JP3096737B1 (ja) * | 1999-07-19 | 2000-10-10 | 工業技術院長 | ヒト・動物細胞培養液 |
| US6613083B2 (en) | 2001-05-02 | 2003-09-02 | Eckhard Alt | Stent device and method |
| WO2023069575A1 (en) * | 2021-10-21 | 2023-04-27 | Parow Entheobiosciences Llc | Method for producing 5-methoxy-n,n-dimethyltryptamine (5-meo-dmt) in vitro |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1594097A (en) * | 1976-12-16 | 1981-07-30 | Int Inst Of Differentiation | Production of specific immune nucleic acids cell dialysates and antibodies |
| US4394448A (en) * | 1978-02-24 | 1983-07-19 | Szoka Jr Francis C | Method of inserting DNA into living cells |
| US4172124A (en) * | 1978-04-28 | 1979-10-23 | The Wistar Institute | Method of producing tumor antibodies |
| JPS5852634B2 (ja) * | 1980-12-05 | 1983-11-24 | 株式会社林原生物化学研究所 | ウロキナ−ゼの製造法 |
| ZA824218B (en) * | 1981-06-29 | 1983-04-27 | Cetus Corp | Plasmid for producing human insulin |
| US4465769A (en) * | 1981-12-11 | 1984-08-14 | The United States Of America As Represented By The Department Of Health And Human Services | Non-transformed thymidine kinaseless cell line and its use for testing tumorigenic potential of genes |
| US4464465A (en) * | 1982-04-05 | 1984-08-07 | Genetic Systems Corporation | Cell-driven viral transfer in eukaryotes |
-
1982
- 1982-12-09 DE DE19823245665 patent/DE3245665A1/de not_active Withdrawn
-
1983
- 1983-04-20 GR GR71148A patent/GR78532B/el unknown
- 1983-04-25 IE IE945/83A patent/IE54881B1/en not_active IP Right Cessation
- 1983-04-26 YU YU00948/83A patent/YU94883A/xx unknown
- 1983-04-28 IL IL68515A patent/IL68515A/xx not_active IP Right Cessation
- 1983-04-29 EP EP83104243A patent/EP0093436B1/de not_active Expired
- 1983-04-29 DE DE8383104243T patent/DE3367412D1/de not_active Expired
- 1983-05-02 DD DD83250509A patent/DD210708A5/de not_active IP Right Cessation
- 1983-05-02 AU AU14141/83A patent/AU538828B2/en not_active Ceased
- 1983-05-03 SU SU833594155A patent/SU1424744A3/ru active
- 1983-05-03 HU HU831514A patent/HU196456B/hu not_active IP Right Cessation
- 1983-05-03 CA CA000427343A patent/CA1201396A/en not_active Expired
- 1983-05-03 PT PT76629A patent/PT76629B/pt not_active IP Right Cessation
- 1983-05-03 FI FI831509A patent/FI85282C/fi not_active IP Right Cessation
- 1983-05-04 DK DK199083A patent/DK199083A/da not_active Application Discontinuation
- 1983-05-04 ES ES522086A patent/ES8402346A1/es not_active Expired
-
1985
- 1985-08-23 JP JP60184369A patent/JPH0753110B2/ja not_active Expired - Lifetime
-
1990
- 1990-09-25 US US07/590,602 patent/US5114847A/en not_active Expired - Fee Related
-
1993
- 1993-06-02 LV LVP-93-462A patent/LV11042B/lv unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0209154A1 (de) | 1985-07-19 | 1987-01-21 | Roche Diagnostics GmbH | Verfahren und Reagenz zur spezifischen Bestimmung von Pankreas-alpha-Amylase |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0093436A2 (de) | 1983-11-09 |
| IE830945L (en) | 1983-11-04 |
| DK199083D0 (da) | 1983-05-04 |
| JPS61205486A (ja) | 1986-09-11 |
| FI831509L (fi) | 1983-11-05 |
| PT76629A (de) | 1983-06-01 |
| AU1414183A (en) | 1983-11-10 |
| GR78532B (enExample) | 1984-09-27 |
| DK199083A (da) | 1983-11-05 |
| DD210708A5 (de) | 1984-06-20 |
| AU538828B2 (en) | 1984-08-30 |
| IE54881B1 (en) | 1990-03-14 |
| LV11042B (en) | 1996-06-20 |
| CA1201396A (en) | 1986-03-04 |
| ES522086A0 (es) | 1984-02-01 |
| EP0093436B1 (de) | 1986-11-05 |
| US5114847A (en) | 1992-05-19 |
| FI85282C (fi) | 1992-03-25 |
| FI85282B (fi) | 1991-12-13 |
| EP0093436A3 (en) | 1984-05-02 |
| FI831509A0 (fi) | 1983-05-03 |
| HU196456B (en) | 1988-11-28 |
| SU1424744A3 (ru) | 1988-09-15 |
| LV11042A (lv) | 1996-02-20 |
| DE3367412D1 (en) | 1986-12-11 |
| ES8402346A1 (es) | 1984-02-01 |
| IL68515A (en) | 1988-11-15 |
| JPH0753110B2 (ja) | 1995-06-07 |
| PT76629B (de) | 1985-12-03 |
| IL68515A0 (en) | 1983-07-31 |
| YU94883A (en) | 1988-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8139 | Disposal/non-payment of the annual fee |