DE3145692C2 - - Google Patents
Info
- Publication number
- DE3145692C2 DE3145692C2 DE3145692A DE3145692A DE3145692C2 DE 3145692 C2 DE3145692 C2 DE 3145692C2 DE 3145692 A DE3145692 A DE 3145692A DE 3145692 A DE3145692 A DE 3145692A DE 3145692 C2 DE3145692 C2 DE 3145692C2
- Authority
- DE
- Germany
- Prior art keywords
- light
- measuring
- measurement
- optical scanning
- cuvette
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000005259 measurement Methods 0.000 claims description 28
- 239000003153 chemical reaction reagent Substances 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 12
- 230000023555 blood coagulation Effects 0.000 claims description 10
- 239000002184 metal Substances 0.000 claims description 9
- 238000003760 magnetic stirring Methods 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- 210000002381 plasma Anatomy 0.000 claims description 5
- 230000005540 biological transmission Effects 0.000 claims description 3
- 206010038743 Restlessness Diseases 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 210000004027 cell Anatomy 0.000 description 11
- 230000015271 coagulation Effects 0.000 description 11
- 238000005345 coagulation Methods 0.000 description 11
- 238000010586 diagram Methods 0.000 description 4
- 238000011534 incubation Methods 0.000 description 3
- 239000005995 Aluminium silicate Substances 0.000 description 2
- 235000012211 aluminium silicate Nutrition 0.000 description 2
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 2
- 241001464057 Electroma Species 0.000 description 1
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4905—Determining clotting time of blood
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
- B01F33/452—Magnetic mixers; Mixers with magnetically driven stirrers using independent floating stirring elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/40—Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
- B01F35/42—Clamping or holding arrangements for mounting receptacles on mixing devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
- G01N21/272—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration for following a reaction, e.g. for determining photometrically a reaction rate (photometric cinetic analysis)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/82—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0367—Supports of cells, e.g. pivotable
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Plasma & Fusion (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Ecology (AREA)
- Theoretical Computer Science (AREA)
- Mathematical Physics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3145692A DE3145692C3 (de) | 1981-11-19 | 1981-11-19 | Verfahren zum Erfassen und Messen der Blutgerinnungszeit und Gerät zur Durchführung des Verfahrens |
| PCT/DE1982/000137 WO1983000228A1 (fr) | 1981-07-11 | 1982-07-02 | Appareil pour la mesure du temps de coagulation du sang et procede pour saisir et mesurer le temps |
| JP57502175A JPS58501096A (ja) | 1981-07-11 | 1982-07-02 | 血液の凝塊時間測定装置及び血液の凝塊時間を決定して測定する方法 |
| EP82902153A EP0083617A1 (de) | 1981-07-11 | 1982-07-02 | Blutgerinnungszeitmessgerät und verfahren zum erfassen und messen der blutgerinnungszeit |
| FR8216419A FR2516658B1 (fr) | 1981-11-19 | 1982-09-29 | Appareil et procede pour detecter et mesurer le temps de coagulation du sang |
| US06/924,155 US4876069A (en) | 1981-07-11 | 1986-10-27 | Blood clotting time measuring apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3145692A DE3145692C3 (de) | 1981-11-19 | 1981-11-19 | Verfahren zum Erfassen und Messen der Blutgerinnungszeit und Gerät zur Durchführung des Verfahrens |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE3145692A1 DE3145692A1 (de) | 1983-05-26 |
| DE3145692C2 true DE3145692C2 (enExample) | 1988-04-07 |
| DE3145692C3 DE3145692C3 (de) | 1995-01-26 |
Family
ID=6146629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE3145692A Expired - Lifetime DE3145692C3 (de) | 1981-07-11 | 1981-11-19 | Verfahren zum Erfassen und Messen der Blutgerinnungszeit und Gerät zur Durchführung des Verfahrens |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE3145692C3 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4113330A1 (de) * | 1991-04-24 | 1992-10-29 | Amelung Gmbh Heinrich | Vorrichtung zur photometrischen bestimmung des gerinnungsverhaltens von blut, blutplasma oder dergleichen |
| DE4440250A1 (de) * | 1994-11-10 | 1996-05-15 | Wtw Weilheim | Meßwerterfassungsvorrichtung |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01123133A (ja) * | 1987-11-09 | 1989-05-16 | Hitachi Ltd | 分光光度計 |
| DE19545018A1 (de) * | 1995-12-02 | 1997-06-05 | Marcel Kastler | Computergesteuertes Polarimeter zur Drehwinkelbeobachtung von Reaktionen unter konstanten Versuchsbedingungen |
| DE10125600A1 (de) * | 2001-05-25 | 2002-12-05 | Schindler Heinz | Verfahren und Vorrichtung zur Charakterisierung und Identifizierung von Mikroorganismenstämmen und Zellinien |
| DE10143869B4 (de) * | 2001-09-07 | 2006-04-13 | november Aktiengesellschaft Gesellschaft für Molekulare Medizin | Vorrichtung zur Überwachung des Koagulationsstatus |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE7707546U1 (enExample) * | 1900-01-01 | Labor Laborgeraete + Analysensysteme Vertriebsgesellschaft Mbh, 2000 Hamburg | ||
| BE498056A (enExample) * | 1949-03-25 | |||
| US3593568A (en) * | 1969-04-01 | 1971-07-20 | Bio Dynamics Inc | Prothrombin time measuring apparatus with means to start the timer in response to the initial decrement of optical transmissivity |
| NL169367C (nl) * | 1970-12-09 | 1982-07-01 | Lode S Instr N V | Werkwijze en inrichting voor het bepalen van de coagulatietijd van bloed. |
| US4135818A (en) * | 1975-01-22 | 1979-01-23 | Bio/Data Corporation | Platelet aggregation monitoring device |
| GB2024418A (en) * | 1978-06-30 | 1980-01-09 | Hycel Inc | Automatic chemical kinetic and end-point analysis |
| US4251768A (en) * | 1978-09-29 | 1981-02-17 | Hycel, Inc. | Coincidence correction of hematocrit in a hematology measurement apparatus |
| US4274744A (en) * | 1978-11-21 | 1981-06-23 | Medico Electronic, Inc. | Direct reading digital colorimeter |
| DE3127560C2 (de) * | 1981-07-11 | 1993-01-14 | Jochimsen, Siegfried, 2300 Kiel | Gerät zum Erfassen und Messen der Blutgerinnungszeit mit einem zur Aufnahme der Meßküvette dienenden temperierbaren Metallblock, einer Rühreinrichtung und einer lichtoptischen Trübungsmeßeinrichtung |
-
1981
- 1981-11-19 DE DE3145692A patent/DE3145692C3/de not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4113330A1 (de) * | 1991-04-24 | 1992-10-29 | Amelung Gmbh Heinrich | Vorrichtung zur photometrischen bestimmung des gerinnungsverhaltens von blut, blutplasma oder dergleichen |
| DE4440250A1 (de) * | 1994-11-10 | 1996-05-15 | Wtw Weilheim | Meßwerterfassungsvorrichtung |
| DE4440250B4 (de) * | 1994-11-10 | 2006-12-21 | WTW Wissenschaftlich-Technische Werkstätten GmbH & Co. KG | Meßwerterfassungsvorrichtung |
Also Published As
| Publication number | Publication date |
|---|---|
| DE3145692C3 (de) | 1995-01-26 |
| DE3145692A1 (de) | 1983-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8110 | Request for examination paragraph 44 | ||
| D2 | Grant after examination | ||
| 8363 | Opposition against the patent | ||
| 8366 | Restricted maintained after opposition proceedings | ||
| 8305 | Restricted maintenance of patent after opposition | ||
| D4 | Patent maintained restricted |