DE3142856C2 - - Google Patents

Info

Publication number
DE3142856C2
DE3142856C2 DE3142856A DE3142856A DE3142856C2 DE 3142856 C2 DE3142856 C2 DE 3142856C2 DE 3142856 A DE3142856 A DE 3142856A DE 3142856 A DE3142856 A DE 3142856A DE 3142856 C2 DE3142856 C2 DE 3142856C2
Authority
DE
Germany
Prior art keywords
dichloro
fluoro
trichloromethylbenzene
acid
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3142856A
Other languages
German (de)
English (en)
Other versions
DE3142856A1 (de
Inventor
Erich Dr. Klauke
Klaus Dr. 5068 Odenthal De Grohe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to DE19813142856 priority Critical patent/DE3142856A1/de
Priority to US06/397,958 priority patent/US4439620A/en
Priority to JP57126842A priority patent/JPS5874638A/ja
Publication of DE3142856A1 publication Critical patent/DE3142856A1/de
Application granted granted Critical
Publication of DE3142856C2 publication Critical patent/DE3142856C2/de
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/68Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
    • C07C63/70Monocarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/093Preparation of halogenated hydrocarbons by replacement by halogens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/093Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/10Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
    • C07C17/14Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms in the side-chain of aromatic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C25/00Compounds containing at least one halogen atom bound to a six-membered aromatic ring
    • C07C25/02Monocyclic aromatic halogenated hydrocarbons
    • C07C25/13Monocyclic aromatic halogenated hydrocarbons containing fluorine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/42Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
    • C07C45/43Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis of >CX2 groups, X being halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/55Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C07C51/305Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with sulfur or sulfur-containing compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/54Preparation of carboxylic acid anhydrides
    • C07C51/56Preparation of carboxylic acid anhydrides from organic acids, their salts, their esters or their halides, e.g. by carboxylation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)
DE19813142856 1981-10-29 1981-10-29 Verfahren zur herstellung von 2,4-dichlor-5-fluor-benzoylchlorid Granted DE3142856A1 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE19813142856 DE3142856A1 (de) 1981-10-29 1981-10-29 Verfahren zur herstellung von 2,4-dichlor-5-fluor-benzoylchlorid
US06/397,958 US4439620A (en) 1981-10-29 1982-07-14 2,4-Dichloro-5-fluorobenzoyl halide and a process for its preparation
JP57126842A JPS5874638A (ja) 1981-10-29 1982-07-22 1―置換―2,4―ジクロロ―5―フルオロベンゼン

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813142856 DE3142856A1 (de) 1981-10-29 1981-10-29 Verfahren zur herstellung von 2,4-dichlor-5-fluor-benzoylchlorid

Publications (2)

Publication Number Publication Date
DE3142856A1 DE3142856A1 (de) 1983-05-11
DE3142856C2 true DE3142856C2 (en, 2012) 1990-01-11

Family

ID=6145082

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19813142856 Granted DE3142856A1 (de) 1981-10-29 1981-10-29 Verfahren zur herstellung von 2,4-dichlor-5-fluor-benzoylchlorid

Country Status (3)

Country Link
US (1) US4439620A (en, 2012)
JP (1) JPS5874638A (en, 2012)
DE (1) DE3142856A1 (en, 2012)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009538878A (ja) * 2006-05-31 2009-11-12 クレール シミー エスアエス ラモトリジンおよびその中間体2,3−ジクロロベンゾイルクロリドの調製法

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3301868A1 (de) * 1983-01-21 1984-07-26 Bayer Ag, 5090 Leverkusen Kernhalogenierte 3-fluortoluole und verfahren zu ihrer herstellung
EP0125803A3 (en) * 1983-04-27 1987-01-21 FISONS plc Pharmaceutically active dihydropyridines
US5262559A (en) * 1983-07-18 1993-11-16 Abbott Laboratories Method of producing quinoline-3-carboxylic acids
US4721787A (en) * 1984-05-10 1988-01-26 Ciba-Geigy Corporation Process for the preparation of benzo-(pyrano and thiopyrano)-pyridines
DE3420798A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-(3-aryl-l-piperazinyl)- sowie 7-(3-cyclohexyl-l-piperazinyl)-3-chinoloncarbonsaeuren
US5530158A (en) * 1984-06-04 1996-06-25 Bayer Aktiengesellschaft 2,4,5-trihalogeno- and 2,3,4,5-tetrahalogenobenzene derivatives
US5200548A (en) * 1984-06-04 1993-04-06 Bayer Aktiengesellschaft 2,4,5-Trihalogeno- and 2,3,4,5-tetrahalogenobenzene derivatives
DE3420796A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 2,4,5-trihalogen- bzw. 2,3,4,5-tetrahalogenbenzolderivate und verfahren zu ihrer herstellung
DE3426482A1 (de) * 1984-07-18 1986-01-30 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von halogenierten aroylessigestern
DE3502935A1 (de) * 1984-09-29 1986-04-10 Bayer Ag, 5090 Leverkusen 3-amino-2-benzoyl-acrylsaeurederivate und ein verfahren zu ihrer herstellung
JPH0610158B2 (ja) * 1985-11-08 1994-02-09 旭硝子株式会社 3−フルオロ安息香酸類の製造方法
JPS62192321A (ja) * 1986-02-19 1987-08-22 Bayer Japan Kk 魚類用抗菌剤
DE3631906A1 (de) * 1986-09-19 1988-03-31 Bayer Ag Verfahren zur herstellung von benzoesaeure-derivaten
US5563138A (en) * 1987-04-16 1996-10-08 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US4833270A (en) * 1987-12-21 1989-05-23 American Cyanamid Company Process for preparing 2-chloro-4,5-difluorobenzoic acid
JPH072679B2 (ja) * 1988-04-15 1995-01-18 旭硝子株式会社 2―クロロ―4,5―ジフルオロ安息香酸誘導体
US4885386A (en) * 1988-10-28 1989-12-05 Warner-Lambert Company Process for the synthesis of 3-chloro-2,4,5-trifluorobenzoic acid
US4876387A (en) * 1989-02-27 1989-10-24 Occidental Chemical Corporation Process for preparing 2,4,5-trifluorobenzoic acid
DE3912263C2 (de) * 1989-04-14 1998-09-17 Bayer Ag Verfahren zur Herstellung von halogenierten Benzoesäurederivaten
US4996355A (en) * 1989-04-14 1991-02-26 Mallinckrodt, Inc. Novel intermediates for the production of 2,4,5-trifluorobenzoyl fluoride
IE72169B1 (en) * 1989-11-17 1997-03-26 Asahi Glass Co Ltd Processes for producing 5-fluorobenzoic acids and their intermediates
JP2595109B2 (ja) * 1989-11-17 1997-03-26 旭硝子株式会社 新規フルオロベンゾトリクロリド化合物およびフルオロ安息香酸類の製造方法
US5532416A (en) * 1994-07-20 1996-07-02 Monsanto Company Benzoyl derivatives and synthesis thereof
DE4133676A1 (de) * 1991-10-11 1993-04-15 Bayer Ag Verfahren zur radikalischen chlorierung oder bromierung von methylaromaten
DE4203792A1 (de) * 1992-02-10 1993-08-12 Bayer Ag Verbessertes verfahren zur herstellung von gegebenenfalls substituierten benzaldehyden
DE4340854A1 (de) * 1993-12-01 1995-09-14 Bayer Ag Verfahren zur Herstellung von 3-Fluor-4,6-dichlortoluol
US5869688A (en) * 1994-07-20 1999-02-09 Monsanto Company Preparation of substituted 3-aryl-5-haloalkyl-pyrazoles having herbicidal activity
DE4445548A1 (de) 1994-12-20 1996-06-27 Bayer Ag Verfahren zur Herstellung von 3-Fluor-4,6-dichlortoluol
US5698708A (en) * 1996-06-20 1997-12-16 Monsanto Company Preparation of substituted 3-aryl-5-haloalkyl-pyrazoles having herbicidal activity
ITMI20050275A1 (it) * 2005-02-22 2006-08-23 Miteni Spa Procedimento per la preparazione di derivati dell'acido benzoico attraverso un nuovo intermedio di sintesi
JP5789430B2 (ja) * 2011-06-27 2015-10-07 イハラニッケイ化学工業株式会社 2−クロロメチルベンズアルデヒドの製造方法、2−クロロメチルベンズアルデヒド含有組成物及びその保管方法
JP5733052B2 (ja) * 2011-06-27 2015-06-10 住友化学株式会社 2−(アリールオキシメチル)ベンズアルデヒド化合物の製造方法
CN104725221B (zh) * 2015-03-19 2016-04-27 浙江本立科技股份有限公司 一种2,4-二氯-5-氟苯甲酰氯的合成方法
CN109678698B (zh) * 2019-01-22 2021-11-02 江苏佳麦化工有限公司 一种2,4-二氯苯甲酰氯的制备方法
CN113929553B (zh) * 2021-12-16 2022-03-25 山东国邦药业有限公司 一种2,4-二氯氟苯的合成方法
CN114105792B (zh) * 2022-01-14 2023-03-31 山东国邦药业有限公司 一种环丙沙星关键中间体的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB308231A (en) * 1927-11-18 1929-03-18 Philip Fletcher Bangham Improvements in and relating to the production of substituted benzoyl halides
US3156553A (en) * 1961-05-01 1964-11-10 Du Pont Composition and method for the control of weeds
DE2652810C3 (de) * 1976-11-20 1979-05-10 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von aromatischen Fluorverbindungen
GB2005667B (en) * 1977-10-03 1982-03-17 Hooker Chemicals Plastics Corp Process for the preparation of benzoyl halide and halosulftonylbenzoul halide
GB2061257B (en) * 1979-10-18 1983-10-12 Dow Chemical Co Method for the preparations of 2-chlorobenzoyl chloride and its uses

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009538878A (ja) * 2006-05-31 2009-11-12 クレール シミー エスアエス ラモトリジンおよびその中間体2,3−ジクロロベンゾイルクロリドの調製法

Also Published As

Publication number Publication date
JPH0450296B2 (en, 2012) 1992-08-13
DE3142856A1 (de) 1983-05-11
US4439620A (en) 1984-03-27
JPS5874638A (ja) 1983-05-06

Similar Documents

Publication Publication Date Title
DE3142856C2 (en, 2012)
DE3420796A1 (de) 2,4,5-trihalogen- bzw. 2,3,4,5-tetrahalogenbenzolderivate und verfahren zu ihrer herstellung
EP0607824B1 (de) Verfahren zur Herstellung mehrfach halogenierter Benzotrichloride und Benzoylchloride sowie neue, mehrfach halogenierte Benzotrichloride
EP0034741B1 (de) Verfahren zur Herstellung eines substituierten Bromfluorbenzols und 3-Brom-4-fluorbenzonitril
EP0176026B1 (de) Verfahren zur Herstellung von 2,4-Dichlor-5-fluor-benzoesäure
DE2916588A1 (de) 1-substituierte cyclohexan-1-carbonsaeuren, verfahren zu deren herstellung sowie diese enthaltende arzneimittel
DE1001261C2 (de) Verfahren zur Herstellung von basischen Estern endocyclisch substituierter Mandelsaeuren und ihren Salzen
DE2950608C2 (en, 2012)
DE3810093A1 (de) Verfahren zur herstellung von tetrafluorbenzoesaeure und deren saeurehalogeniden
EP0048375B1 (de) Verfahren zur Herstellung von 3-Brom-4-fluor-benzoesäure
DE69308144T2 (de) Pyridinium-intermediate und verfahren zu deren herstellung
DE2537288A1 (de) Herstellung von trifluormethylsubstituierten aminobenzonitrilen
EP0608714B1 (de) Verfahren zur Herstellung chlorierter 4,5-Difluorbenzoesäuren, -benzoesäurederivate und -benzaldehyde
DE2625163A1 (de) Alpha-chlorcarbonsaeuren und verfahren zu ihrer herstellung
DE4123322C2 (de) 2-Chlor-3,4,5-trifluorbenzoesäure 2,2'-Dichlor-3,4,5-trifluoracetophenon, 2,2',2'-Trichlor-3,4,5-trifluoracetophenon, 5,2'-Dichlor-2,3,4-trifluoracetophenon und 5,2',2'-Trichlor-2,3,4-trifluoracetophenon und Verfahren zur Herstellung dieser Verbindungen und der isomeren 5-Chlor-2,3,4-trifluorbenzoesäure
DE2415748A1 (de) Verfahren zur herstellung von polyhalogenierten nicotinsaeuren
DE2613838A1 (de) Verfahren zum erzeugen der eckige klammer auf o-(2,6-dichloranilino)- phenyl eckige klammer zu -essigsaeure und von salzen derselben
DE2931255C2 (en, 2012)
AT354432B (de) Verfahren zur herstellung von 3-indolylessig- saeuren
DE2619321C2 (de) Oxalsäurederivate, ihre Herstellung und ihre Verwendung
DE2415062C3 (de) Verfahren zur Herstellung von 2-Nitrobenzaldehyd
DE1008300B (de) Verfahren zur Herstellung von basisch substituierten Coffeinderivaten
DE2660213C2 (de) Verfahren zur Herstellung von Acylcyaniden
DE1695617A1 (de) Verfahren zur Herstellung von neuen Dibenzocycloheptatrienderivaten
DE1793467C (de) Verfahren zur Herstellung von 4-Hydroxybenzonitrilen

Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition