DE3066676D1 - Substituted acetophenones, their preparation and pharmaceutical compositions containing them - Google Patents

Substituted acetophenones, their preparation and pharmaceutical compositions containing them

Info

Publication number
DE3066676D1
DE3066676D1 DE8080102661T DE3066676T DE3066676D1 DE 3066676 D1 DE3066676 D1 DE 3066676D1 DE 8080102661 T DE8080102661 T DE 8080102661T DE 3066676 T DE3066676 T DE 3066676T DE 3066676 D1 DE3066676 D1 DE 3066676D1
Authority
DE
Germany
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
substituted acetophenones
acetophenones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080102661T
Other languages
German (de)
English (en)
Inventor
Isao Umeda
Hideo Ishitsuka
Nobuo Shinma
Yasuji Suhara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE3066676D1 publication Critical patent/DE3066676D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/12Esters of phosphoric acids with hydroxyaryl compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06Benzopyran radicals
    • C07H17/065Benzo[b]pyrans
    • C07H17/07Benzo[b]pyran-4-ones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
DE8080102661T 1979-05-23 1980-05-13 Substituted acetophenones, their preparation and pharmaceutical compositions containing them Expired DE3066676D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7917973 1979-05-23

Publications (1)

Publication Number Publication Date
DE3066676D1 true DE3066676D1 (en) 1984-03-29

Family

ID=10505387

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080102661T Expired DE3066676D1 (en) 1979-05-23 1980-05-13 Substituted acetophenones, their preparation and pharmaceutical compositions containing them

Country Status (25)

Country Link
US (1) US4327088A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0021000B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS55157534A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR230064A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE6357T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU538581B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR8003235A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1137082A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (1) CS212716B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CU (1) CU35266A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3066676D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK224980A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES8104812A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI67556C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR67305B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU184288B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE49816B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL60115A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MC (1) MC1330A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO152898C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ193750A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH16056A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT71289B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU140280A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA802927B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6385526A (ja) * 1986-09-30 1988-04-16 Nippon Oil & Fats Co Ltd 非線形光学材料
AU635156B2 (en) * 1990-09-20 1993-03-11 Merrell Dow Pharmaceuticals Inc. Calcium uptake inhibitors
IL118657A0 (en) * 1996-06-14 1996-10-16 Arad Dorit Inhibitors for picornavirus proteases
IL122591A0 (en) 1997-12-14 1998-06-15 Arad Dorit Pharmaceutical compositions comprising cystein protease inhibitors
CA2371910A1 (en) 1999-01-21 2000-07-27 Brian E. Peerce Inhibitors of intestinal apical membrane na/phosphate co-transportation
US20030162753A1 (en) * 1999-01-21 2003-08-28 Peerce Brian E. Inhibition of intestinal apical membrane Na/phosphate co-transportation in humans
US20080027075A1 (en) * 2003-10-31 2008-01-31 Lica Pharmaceuticals A/S Quaternary Amino-Function Chalcones
US20060270614A1 (en) * 2005-05-24 2006-11-30 Sekhar Boddupalli Use of chalcones for the treatment of viral disorders

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL102449C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1949-11-30
GB1007332A (en) * 1960-12-09 1965-10-13 Cooper Mcdougall & Robertson New halogen-containing phosphoric and thiophosphoric acid esters and formulations containing them
FR1476531A (fr) 1965-04-26 1967-04-14 Chimetron Sarl Nouvelles cétones halogénées dérivées du benzimidazole
US3583894A (en) * 1968-03-29 1971-06-08 Us Agriculture Enzyme preparation of hesperetin dihydrochalcone glucoside
US3629322A (en) * 1969-02-17 1971-12-21 Buckman Labor Inc Organic esters and their use as ultraviolet light absorbers and as heat stabilizers
GB1283981A (en) 1969-03-05 1972-08-02 Orsymonde 2,4,6-trihydroxy chalcone derivatives
GB1398528A (en) * 1971-08-17 1975-06-25 Leo Ab Pharmaceutically active secondary phosphoric acid esters
JPS598250B2 (ja) * 1974-02-09 1984-02-23 大正製薬株式会社 カルコンエ−テルの合成法
JPS598249B2 (ja) * 1974-01-19 1984-02-23 大正製薬株式会社 カルコン類の合成法
JPS5912094B2 (ja) * 1974-01-19 1984-03-21 大正製薬株式会社 カルコン体の合成法
JPS593460B2 (ja) * 1974-04-19 1984-01-24 大正製薬株式会社 カルコンルイ ノ ゴウセイホウ
JPS598251B2 (ja) * 1974-04-19 1984-02-23 大正製薬株式会社 イソプレニルカルコン類の合成法
JPS50140430A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1974-04-23 1975-11-11
FR2307820A1 (fr) * 1975-04-17 1976-11-12 Hayashibara Seibutsu Chem Inst Glycosides d'echinatine et leur preparation
DD123466A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-12-01 1976-12-20
US4122191A (en) * 1976-12-20 1978-10-24 Richardson-Merrell Inc. Antirhinovirus agents
US4154756A (en) * 1977-12-15 1979-05-15 American Cyanamid Company 2-Substituted-4'-(monoalkylamino)-acetophenones
NZ192641A (en) * 1979-01-26 1984-10-19 Hoffmann La Roche Substituted acetophenones and pharmaceutical compositions

Also Published As

Publication number Publication date
FI67556C (fi) 1985-04-10
ES491728A0 (es) 1981-04-01
NO152898C (no) 1985-12-11
CU35266A (en) 1982-03-28
FI67556B (fi) 1984-12-31
HU184288B (en) 1984-07-30
IL60115A0 (en) 1980-07-31
US4327088A (en) 1982-04-27
EP0021000A2 (de) 1981-01-07
AR230064A1 (es) 1984-02-29
IE801068L (en) 1980-11-23
JPS55157534A (en) 1980-12-08
AU5846580A (en) 1980-11-27
IE49816B1 (en) 1985-12-25
CA1137082A (en) 1982-12-07
PH16056A (en) 1983-06-09
ES8104812A1 (es) 1981-04-01
IL60115A (en) 1986-02-28
PT71289A (en) 1980-06-01
GR67305B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-06-29
NZ193750A (en) 1984-12-14
BR8003235A (pt) 1980-12-30
NO801542L (no) 1980-11-24
MC1330A1 (fr) 1981-04-21
ZA802927B (en) 1982-01-27
FI801661A7 (fi) 1980-11-21
YU140280A (en) 1983-12-31
EP0021000A3 (en) 1981-12-02
NO152898B (no) 1985-09-02
AU538581B2 (en) 1984-08-23
EP0021000B1 (de) 1984-02-22
PT71289B (en) 1981-09-21
CS212716B2 (en) 1982-03-26
ATE6357T1 (de) 1984-03-15
DK224980A (da) 1980-11-24

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee