ATE6357T1 - Substituierte acetophenone, deren herstellung und pharmazeutische praeparate, die sie enthalten. - Google Patents

Substituierte acetophenone, deren herstellung und pharmazeutische praeparate, die sie enthalten.

Info

Publication number
ATE6357T1
ATE6357T1 AT80102661T AT80102661T ATE6357T1 AT E6357 T1 ATE6357 T1 AT E6357T1 AT 80102661 T AT80102661 T AT 80102661T AT 80102661 T AT80102661 T AT 80102661T AT E6357 T1 ATE6357 T1 AT E6357T1
Authority
AT
Austria
Prior art keywords
production
pharmaceutical preparations
preparations containing
substituted acetophenones
acetophenones
Prior art date
Application number
AT80102661T
Other languages
German (de)
English (en)
Inventor
Isao Umeda
Hideo Ishitsuka
Nobuo Shinma
Yasuji Suhara
Original Assignee
F. Hoffmann-La Roche & Co. Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche & Co. Aktiengesellschaft filed Critical F. Hoffmann-La Roche & Co. Aktiengesellschaft
Application granted granted Critical
Publication of ATE6357T1 publication Critical patent/ATE6357T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/12Esters of phosphoric acids with hydroxyaryl compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06Benzopyran radicals
    • C07H17/065Benzo[b]pyrans
    • C07H17/07Benzo[b]pyran-4-ones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Saccharide Compounds (AREA)
AT80102661T 1979-05-23 1980-05-13 Substituierte acetophenone, deren herstellung und pharmazeutische praeparate, die sie enthalten. ATE6357T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7917973 1979-05-23
EP80102661A EP0021000B1 (de) 1979-05-23 1980-05-13 Substituierte Acetophenone, deren Herstellung und pharmazeutische Präparate, die sie enthalten

Publications (1)

Publication Number Publication Date
ATE6357T1 true ATE6357T1 (de) 1984-03-15

Family

ID=10505387

Family Applications (1)

Application Number Title Priority Date Filing Date
AT80102661T ATE6357T1 (de) 1979-05-23 1980-05-13 Substituierte acetophenone, deren herstellung und pharmazeutische praeparate, die sie enthalten.

Country Status (25)

Country Link
US (1) US4327088A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0021000B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS55157534A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR230064A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE6357T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU538581B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR8003235A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1137082A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (1) CS212716B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CU (1) CU35266A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3066676D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK224980A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES8104812A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI67556C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR67305B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU184288B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE49816B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL60115A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MC (1) MC1330A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO152898C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ193750A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH16056A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT71289B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU140280A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA802927B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6385526A (ja) * 1986-09-30 1988-04-16 Nippon Oil & Fats Co Ltd 非線形光学材料
AU635156B2 (en) * 1990-09-20 1993-03-11 Merrell Dow Pharmaceuticals Inc. Calcium uptake inhibitors
IL118657A0 (en) * 1996-06-14 1996-10-16 Arad Dorit Inhibitors for picornavirus proteases
IL122591A0 (en) 1997-12-14 1998-06-15 Arad Dorit Pharmaceutical compositions comprising cystein protease inhibitors
US20030162753A1 (en) * 1999-01-21 2003-08-28 Peerce Brian E. Inhibition of intestinal apical membrane Na/phosphate co-transportation in humans
WO2000043402A2 (en) 1999-01-21 2000-07-27 Board Of Regents, The University Of Texas System Inhibitors of intestinal apical membrane na/phosphate co-transportation
US20080027075A1 (en) * 2003-10-31 2008-01-31 Lica Pharmaceuticals A/S Quaternary Amino-Function Chalcones
US20060270614A1 (en) * 2005-05-24 2006-11-30 Sekhar Boddupalli Use of chalcones for the treatment of viral disorders

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL102449C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1949-11-30
GB1007332A (en) * 1960-12-09 1965-10-13 Cooper Mcdougall & Robertson New halogen-containing phosphoric and thiophosphoric acid esters and formulations containing them
FR1476531A (fr) 1965-04-26 1967-04-14 Chimetron Sarl Nouvelles cétones halogénées dérivées du benzimidazole
US3583894A (en) * 1968-03-29 1971-06-08 Us Agriculture Enzyme preparation of hesperetin dihydrochalcone glucoside
US3629322A (en) * 1969-02-17 1971-12-21 Buckman Labor Inc Organic esters and their use as ultraviolet light absorbers and as heat stabilizers
GB1283981A (en) 1969-03-05 1972-08-02 Orsymonde 2,4,6-trihydroxy chalcone derivatives
GB1398528A (en) * 1971-08-17 1975-06-25 Leo Ab Pharmaceutically active secondary phosphoric acid esters
JPS598250B2 (ja) * 1974-02-09 1984-02-23 大正製薬株式会社 カルコンエ−テルの合成法
JPS598249B2 (ja) * 1974-01-19 1984-02-23 大正製薬株式会社 カルコン類の合成法
JPS5912094B2 (ja) * 1974-01-19 1984-03-21 大正製薬株式会社 カルコン体の合成法
JPS598251B2 (ja) * 1974-04-19 1984-02-23 大正製薬株式会社 イソプレニルカルコン類の合成法
JPS593460B2 (ja) * 1974-04-19 1984-01-24 大正製薬株式会社 カルコンルイ ノ ゴウセイホウ
JPS50140430A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1974-04-23 1975-11-11
FR2307820A1 (fr) * 1975-04-17 1976-11-12 Hayashibara Seibutsu Chem Inst Glycosides d'echinatine et leur preparation
DD123466A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-12-01 1976-12-20
US4122191A (en) * 1976-12-20 1978-10-24 Richardson-Merrell Inc. Antirhinovirus agents
US4154756A (en) * 1977-12-15 1979-05-15 American Cyanamid Company 2-Substituted-4'-(monoalkylamino)-acetophenones
NZ192641A (en) * 1979-01-26 1984-10-19 Hoffmann La Roche Substituted acetophenones and pharmaceutical compositions

Also Published As

Publication number Publication date
NZ193750A (en) 1984-12-14
ES491728A0 (es) 1981-04-01
DE3066676D1 (en) 1984-03-29
AU5846580A (en) 1980-11-27
EP0021000A3 (en) 1981-12-02
HU184288B (en) 1984-07-30
PT71289B (en) 1981-09-21
JPS55157534A (en) 1980-12-08
GR67305B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-06-29
IE49816B1 (en) 1985-12-25
FI67556B (fi) 1984-12-31
BR8003235A (pt) 1980-12-30
US4327088A (en) 1982-04-27
AR230064A1 (es) 1984-02-29
NO801542L (no) 1980-11-24
FI67556C (fi) 1985-04-10
IE801068L (en) 1980-11-23
EP0021000B1 (de) 1984-02-22
ZA802927B (en) 1982-01-27
ES8104812A1 (es) 1981-04-01
IL60115A (en) 1986-02-28
FI801661A7 (fi) 1980-11-21
PT71289A (en) 1980-06-01
CU35266A (en) 1982-03-28
NO152898B (no) 1985-09-02
DK224980A (da) 1980-11-24
CA1137082A (en) 1982-12-07
NO152898C (no) 1985-12-11
MC1330A1 (fr) 1981-04-21
CS212716B2 (en) 1982-03-26
YU140280A (en) 1983-12-31
AU538581B2 (en) 1984-08-23
PH16056A (en) 1983-06-09
EP0021000A2 (de) 1981-01-07
IL60115A0 (en) 1980-07-31

Similar Documents

Publication Publication Date Title
NL190664B (nl) Gesubstitueerde benzhydrylpiperidinoderivaten met therapeutische werking en farmaceutische preparaten die deze verbindingen bevatten.
DE10199027I2 (de) Fluorcytidinderivate deren Herstellung und Arzneimittel die diese Derivate enthalten
NL190552B (nl) 1-fenyl-4-alkyl-7,8-dialkoxy-5h-2,3-benzodiazepinederivaten en farmaceutische preparaten, die deze bevatten.
NL950014I1 (nl) Met sulfamoyl gesubstitueerde fenetylaminederivaten, de bereiding daarvan en farmaceutische preparaten, die deze derivaten bevatten.
NL193420B (nl) Antibiotische verbindingen, preparaten die deze bevatten en gebruik ervan.
DE3669104D1 (de) Pharmazeutische praeparate, die ascorbinsaeurederivate enthalten.
IT8247937A0 (it) Polipeptedi, loro preparazione eloro impiego come medicamenti
NL990010I1 (nl) Ä3HÜ-imidazo-Ä5,1-dÜ-1,2,3,5-tetrazine-4-on derivaten en farmaceutische samenstellingen, die deze derivaten bevatten.
FI803264A7 (fi) 2-hydroksialkyyli-3,4,5- trihydroksipiperidiinejä, menetelmä niiden valmistamiseksi sekä niidenkäyttö lääkeaineina.
NL191307C (nl) Analgetisch werkzame piperazinederivaten en farmaceutische preparaten, die deze derivaten bevatten.
FI803356A7 (fi) Uudet atsepinoindolit, niiden valmistus ja niitä sisältävät farmaseuttiset yhdisteet.
ATE6357T1 (de) Substituierte acetophenone, deren herstellung und pharmazeutische praeparate, die sie enthalten.
DE3575422D1 (de) Benzo-a,d,h-b,d-cinnolin-verbindungen, deren herstellung und arzneimittel die diese enthalten.
FI802023A7 (fi) 1-alkadien-2,4- yyli-hydroksimetyyli-3,4,5-trihydroksipiperidiinit, menetelmä niiden valmistamiseksi ja niiden käyttö lääkeaineina.
NL7708306A (nl) 2-benzylpyrrolidinen, werkwijzen ter bereiding daarvan en geneesmiddelen, die deze verbin- dingen bevatten.
DE3578597D1 (de) 4-phenylphthalazin-derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.
IT8322612A0 (it) Polipeptidi, loro preparazione eloro impiego come medicamenti.
FI800350A7 (fi) Dehydropeptidejä, menetelmiä niiden valmistamiseksi sekä niiden käyttö lääkeaineina.
ATE8460T1 (de) Pharmazeutische praeparate und deren herstellung.
NL177214C (nl) Geneeskrachtige preparaten met antimycotische eigenschappen, die 2,4-dichloorfenylimidazolylverbindingen bevatten, alsmede geneeskrachtige verbindingen geschikt voor gebruik in deze preparaten.
NL190120C (nl) 2,3-dihydro-4h-1-benzopyran-4-on-0-carbamoyloximen alsmede farmaceutisch preparaat daarvan.
NL7812644A (nl) N-koolwaterstofacylaminoalkaancarbonzuren, bereiding en toepassing daarvan, benevens geneesmiddelen, die deze verbindingen bevatten.
ATE9162T1 (de) 6-alpha-9-alpha-difluor-16-beta-methylprednisolon-17,21-diester und pharmazeutische zusammensetzungen, die sie enthalten.
ATE15806T1 (de) 6-alpha-fluor-9-alpha-chlor-prednisolon-17,21diester, pharmazeutische zusammensetzungen, die sie enthalten, und zwischenprodukte.
DE68902789D1 (de) 4-hydroxy-isoxazol-derivate, deren herstellung und kosmetische und pharmazeutische zusammensetzungen, die sie enthalten.

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee