DE3036449C2 - Verfahren zur Herstellung einer eine physiologisch aktive Substanz enthaltenden Zusammensetzung mit kontrollierter Wirkstoffreigabe - Google Patents

Verfahren zur Herstellung einer eine physiologisch aktive Substanz enthaltenden Zusammensetzung mit kontrollierter Wirkstoffreigabe

Info

Publication number
DE3036449C2
DE3036449C2 DE3036449A DE3036449A DE3036449C2 DE 3036449 C2 DE3036449 C2 DE 3036449C2 DE 3036449 A DE3036449 A DE 3036449A DE 3036449 A DE3036449 A DE 3036449A DE 3036449 C2 DE3036449 C2 DE 3036449C2
Authority
DE
Germany
Prior art keywords
physiologically active
active substance
dispersed
adsorbent
mixed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3036449A
Other languages
German (de)
English (en)
Other versions
DE3036449A1 (de
Inventor
Isao Kaetsu
Masaru Takasaki Gunma Yoshida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Atomic Energy Agency
Original Assignee
Japan Atomic Energy Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Atomic Energy Research Institute filed Critical Japan Atomic Energy Research Institute
Publication of DE3036449A1 publication Critical patent/DE3036449A1/de
Application granted granted Critical
Publication of DE3036449C2 publication Critical patent/DE3036449C2/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/44—Polymerisation in the presence of compounding ingredients, e.g. plasticisers, dyestuffs, fillers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/46—Polymerisation initiated by wave energy or particle radiation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE3036449A 1979-09-27 1980-09-26 Verfahren zur Herstellung einer eine physiologisch aktive Substanz enthaltenden Zusammensetzung mit kontrollierter Wirkstoffreigabe Expired DE3036449C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12319879A JPS5646807A (en) 1979-09-27 1979-09-27 Production of composition of complex gradually releasing physiologically active substance

Publications (2)

Publication Number Publication Date
DE3036449A1 DE3036449A1 (de) 1981-04-16
DE3036449C2 true DE3036449C2 (de) 1984-09-06

Family

ID=14854615

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3036449A Expired DE3036449C2 (de) 1979-09-27 1980-09-26 Verfahren zur Herstellung einer eine physiologisch aktive Substanz enthaltenden Zusammensetzung mit kontrollierter Wirkstoffreigabe

Country Status (3)

Country Link
US (1) US4379038A (enExample)
JP (1) JPS5646807A (enExample)
DE (1) DE3036449C2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58113102A (ja) * 1981-12-26 1983-07-05 Earth Chem Corp Ltd 薬剤の徐放化材
DE3367683D1 (en) * 1982-06-21 1987-01-02 Hoechst Ag Photopolymerizable mixture and photopolymerizable copying material produced therewith
US4652443A (en) * 1983-06-07 1987-03-24 Japan Atomic Energy Research Institute Slow-release composite and process for producing the same
NL8401362A (nl) * 1984-04-27 1985-11-18 Tno Werkwijze voor het met een polymeer omhullen van deeltjesvormige materialen teneinde de gereguleerde afgifte van deze materialen aan de omgeving mogelijk te maken alsmede aldus verkregen omhuld deeltjesvormig materiaal.
JPS6245537A (ja) * 1985-08-23 1987-02-27 Sumitomo Electric Ind Ltd 医用樹脂組成物及びその製造方法
US5034428A (en) * 1986-06-19 1991-07-23 Board Of Regents Of The University Of Washington Immobilized biomolecules and method of making same
US4829098A (en) * 1986-06-19 1989-05-09 Washington Research Foundation Immobilized biomolecules and method of making same
CA2028804C (en) * 1989-11-21 2000-06-20 Howard J. Buttery Biomosaic polymers and method for preparing same
RO113611B1 (ro) * 1990-08-03 1998-09-30 Asta Pharma Ag Preparate solide de ifosfamida, administrate oral si procedeu de obtinere
JP3153135B2 (ja) 1996-10-15 2001-04-03 三洋化成工業株式会社 抗菌性吸水剤組成物およびその製造法
JP2007530684A (ja) * 2004-03-30 2007-11-01 ユーロ−セルティーク エス．エイ． 吸着剤と逆作用薬とを含有する不正使用防止投与剤型
JPWO2020194723A1 (enExample) * 2019-03-28 2020-10-01

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3577512A (en) * 1968-10-11 1971-05-04 Nat Patent Dev Corp Sustained release tablets
US3767790A (en) * 1972-02-11 1973-10-23 Nat Patent Dev Corp Microorganisms
GB1439132A (en) * 1972-03-13 1976-06-09 Special Polymers Ltd Method for the production of a hydrophilic polymer product
US3901966A (en) * 1973-09-10 1975-08-26 Union Corp Sustained release of methantheline
US3900559A (en) * 1973-09-10 1975-08-19 Union Corp Sustained release of methantheline
US3901968A (en) * 1973-09-10 1975-08-26 Union Corp Sustained release of methantheline
US4025391A (en) * 1974-06-15 1977-05-24 Director Of National Food Research Institute Preparation of bead-shaped immobilized enzyme
JPS5231981A (en) * 1975-08-18 1977-03-10 Takeda Chem Ind Ltd Microcapsule preparation method
US4218437A (en) * 1976-07-23 1980-08-19 Henkel Kommanditgesellschaft Auf Aktien (Henkel Kgaa) Animal feeds containing a mixture of virginiamycin, zinc bacitracin or flavophospholipol and proteolytic enzymes
JPS53146411A (en) 1977-05-27 1978-12-20 Nat Jutaku Kenzai Method of reinforcing foundation
CA1125698A (en) * 1978-03-09 1982-06-15 Masaru Yoshida Process for preparing a polymer composition
US4144327A (en) * 1978-03-20 1979-03-13 G. D. Searle & Co. Antimicrobial composition comprising lytic enzymes from physarum and an antimycotic agent
JPS5585516A (en) * 1978-11-27 1980-06-27 Japan Atom Energy Res Inst Method of preparing polymer composition containing carcinostatic substance
JPS55110105A (en) * 1979-02-19 1980-08-25 Japan Atom Energy Res Inst Preparation of polymer composition containing physiologically active material

Also Published As

Publication number Publication date
US4379038A (en) 1983-04-05
DE3036449A1 (de) 1981-04-16
JPS6346723B2 (enExample) 1988-09-19
JPS5646807A (en) 1981-04-28

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8125 Change of the main classification

Ipc: A61K 9/00

D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee