DE3035057C2 - 6"-Desoxy- und 4",6"-Didesoxy-dibekacin sowie deren 1-N(L-4-Amino-2-hydroxybutyryl)-Derivate. Verfahren zu Ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel - Google Patents

6"-Desoxy- und 4",6"-Didesoxy-dibekacin sowie deren 1-N(L-4-Amino-2-hydroxybutyryl)-Derivate. Verfahren zu Ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Info

Publication number
DE3035057C2
DE3035057C2 DE3035057A DE3035057A DE3035057C2 DE 3035057 C2 DE3035057 C2 DE 3035057C2 DE 3035057 A DE3035057 A DE 3035057A DE 3035057 A DE3035057 A DE 3035057A DE 3035057 C2 DE3035057 C2 DE 3035057C2
Authority
DE
Germany
Prior art keywords
ddkb
dibekacin
solution
amino
groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3035057A
Other languages
German (de)
English (en)
Other versions
DE3035057A1 (de
Inventor
Shinichi Yokohama Kanagawa Kondo
Hamao Tokyo Umezawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of DE3035057A1 publication Critical patent/DE3035057A1/de
Application granted granted Critical
Publication of DE3035057C2 publication Critical patent/DE3035057C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE3035057A 1979-09-19 1980-09-17 6"-Desoxy- und 4",6"-Didesoxy-dibekacin sowie deren 1-N(L-4-Amino-2-hydroxybutyryl)-Derivate. Verfahren zu Ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel Expired DE3035057C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11932379A JPS5643297A (en) 1979-09-19 1979-09-19 6"-deoxydibeckacin or 4",6"-dideoxydibeckacin, their 1-n-acyl derivative, and their preparation

Publications (2)

Publication Number Publication Date
DE3035057A1 DE3035057A1 (de) 1981-04-09
DE3035057C2 true DE3035057C2 (de) 1982-10-14

Family

ID=14758610

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3035057A Expired DE3035057C2 (de) 1979-09-19 1980-09-17 6"-Desoxy- und 4",6"-Didesoxy-dibekacin sowie deren 1-N(L-4-Amino-2-hydroxybutyryl)-Derivate. Verfahren zu Ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Country Status (6)

Country Link
US (1) US4332794A (enExample)
JP (1) JPS5643297A (enExample)
CA (1) CA1177828A (enExample)
DE (1) DE3035057C2 (enExample)
FR (1) FR2465744A1 (enExample)
GB (1) GB2058774B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58203650A (ja) * 1982-05-21 1983-11-28 Victor Co Of Japan Ltd テ−プ走行表示装置
JPS5953498A (ja) * 1982-09-20 1984-03-28 Microbial Chem Res Found ５，２′，３′，４′，４″，６″−ヘキサデオキシカナマイシンおよびその１−ｎ−アシル誘導体
US4656160A (en) * 1984-11-29 1987-04-07 Fujisawa Pharmaceutical Co., Ltd. Aminoglycoside derivatives

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS507595B1 (enExample) * 1970-07-29 1975-03-27
USRE28647E (en) * 1971-06-02 1975-12-09 Preparation of 3-4 dideoxykanamycin B active against resistant bacteria
US3929762A (en) * 1972-08-23 1975-12-30 Microbial Chem Res Found 3{40 -Deoxy derivatives of neamine and its related aminoglycosidic antibiotics, and the production thereof
JPS5324415B2 (enExample) * 1972-10-06 1978-07-20
US4107424A (en) * 1972-10-06 1978-08-15 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai 1-N-[(S)-α-hydroxy-ω-aminoacyl] derivatives of 3',4'-dideoxykanamycin B and 3'-deoxykanamycin B antibiotics
SE402777C (sv) * 1972-12-29 1979-02-05 Takeda Chemical Industries Ltd Sett att framstella aminoglykosidantibiotika av 3'- och/eller 5''-dioxineomycintyp, 3'- och/eller 2''-dioxikanamycintyp eller 3''-dioxistryptomycintyp
CH630644A5 (de) * 1974-04-10 1982-06-30 Takeda Chemical Industries Ltd Verfahren zur herstellung von desoxyaminoglykosid-antibiotika.
US4051315A (en) * 1974-11-13 1977-09-27 Bristol-Myers Company 6"-Deoxykanamycin B and 6"-deoxytobramycin
CA1053666A (en) * 1974-11-13 1979-05-01 John C. Godfrey 6"-deoxykanamycin b and 6"-deoxytobramycin
JPS6029720B2 (ja) * 1975-12-11 1985-07-12 財団法人微生物化学研究会 ３′，４′‐ジデオキシカナマイシンｂの新規な製造法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS-ERMITTELT

Also Published As

Publication number Publication date
CA1177828A (en) 1984-11-13
FR2465744A1 (fr) 1981-03-27
GB2058774A (en) 1981-04-15
GB2058774B (en) 1983-03-02
DE3035057A1 (de) 1981-04-09
JPS5643297A (en) 1981-04-21
JPS6312079B2 (enExample) 1988-03-17
US4332794A (en) 1982-06-01
FR2465744B1 (enExample) 1983-06-24

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