DE3016110C2 - - Google Patents

Info

Publication number
DE3016110C2
DE3016110C2 DE3016110A DE3016110A DE3016110C2 DE 3016110 C2 DE3016110 C2 DE 3016110C2 DE 3016110 A DE3016110 A DE 3016110A DE 3016110 A DE3016110 A DE 3016110A DE 3016110 C2 DE3016110 C2 DE 3016110C2
Authority
DE
Germany
Prior art keywords
chlorhexidine
acid
phosphanilic
nalidixic
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3016110A
Other languages
German (de)
English (en)
Other versions
DE3016110A1 (de
Inventor
Paul L. Clarence N.Y. Us Warner Jun.
Grey B. East Amherst N.Y. Us Kornegay
George Williamsville N.Y. Us Redl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of DE3016110A1 publication Critical patent/DE3016110A1/de
Application granted granted Critical
Publication of DE3016110C2 publication Critical patent/DE3016110C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
    • C07C279/265—X and Y being nitrogen atoms, i.e. biguanides containing two or more biguanide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C07C57/10—Sorbic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3834—Aromatic acids (P-C aromatic linkage)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
DE19803016110 1979-04-26 1980-04-25 Antibakterielle verbindungen, verfahren zu ihrer herstellung und daraus hergestellte mittel Granted DE3016110A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3359379A 1979-04-26 1979-04-26

Publications (2)

Publication Number Publication Date
DE3016110A1 DE3016110A1 (de) 1980-11-06
DE3016110C2 true DE3016110C2 (enrdf_load_stackoverflow) 1990-12-13

Family

ID=21871298

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19803016110 Granted DE3016110A1 (de) 1979-04-26 1980-04-25 Antibakterielle verbindungen, verfahren zu ihrer herstellung und daraus hergestellte mittel

Country Status (13)

Country Link
JP (1) JPS55149242A (enrdf_load_stackoverflow)
AT (1) AT373235B (enrdf_load_stackoverflow)
CA (1) CA1159834A (enrdf_load_stackoverflow)
CH (2) CH648755A5 (enrdf_load_stackoverflow)
CY (2) CY1316A (enrdf_load_stackoverflow)
DE (1) DE3016110A1 (enrdf_load_stackoverflow)
ES (1) ES8105259A1 (enrdf_load_stackoverflow)
FR (1) FR2455034A1 (enrdf_load_stackoverflow)
GB (2) GB2053195B (enrdf_load_stackoverflow)
HK (2) HK1486A (enrdf_load_stackoverflow)
IT (1) IT1188929B (enrdf_load_stackoverflow)
MY (2) MY8600495A (enrdf_load_stackoverflow)
NL (1) NL8002483A (enrdf_load_stackoverflow)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050058673A1 (en) * 2003-09-09 2005-03-17 3M Innovative Properties Company Antimicrobial compositions and methods
CA2599667C (en) 2005-03-10 2014-12-16 3M Innovative Properties Company Antimicrobial compositions comprising esters of hydroxy carboxylic acids
TW200719884A (en) 2005-03-10 2007-06-01 3M Innovative Properties Co Methods of treating ear infections
CN101175474B (zh) 2005-03-10 2011-09-07 3M创新有限公司 降低微生物污染的方法
EP2501676A2 (en) * 2009-11-18 2012-09-26 Medichem, S.A. A di(4-chloro-phenyldiguanido) derivative which is free of potential genotoxicity and a process for reducing the residual amount of p-chloroaniline in said di(4-chloro-phenyldiguanido) derivative

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB815800A (en) * 1956-06-06 1959-07-01 Ici Ltd New biguanide salts
US2684924A (en) * 1951-02-05 1954-07-27 Ici Ltd Nu-chlorophenyldiguanidino compounds
US2990425A (en) * 1956-06-06 1961-06-27 Ici Ltd New biguanide salts
US3159537A (en) * 1960-12-20 1964-12-01 American Cyanamid Co Potentiation of tetracycline by phosphinic acid
BE612641A (enrdf_load_stackoverflow) * 1961-01-18
US3694447A (en) * 1970-03-10 1972-09-26 Smith Kline French Lab Complexes of phosphanilic acid and 9-amino-3-nitroacridine
US3794723A (en) * 1970-03-10 1974-02-26 Smithkline Corp Complexes of phosphanilic acid and 9-amino-3-nitroacridine useful as antifungal or antibacterial agents
SE370003B (enrdf_load_stackoverflow) * 1971-05-18 1974-09-30 Kema Nord Ab
GB1338003A (en) * 1971-06-18 1973-11-21 Ici Ltd Cleaning compositions
SE374658B (enrdf_load_stackoverflow) * 1972-07-31 1975-03-17 Hesselgren S G
US3976765A (en) * 1973-11-01 1976-08-24 Colgate-Palmolive Company Antibacterial oral preparations
US4125610A (en) * 1977-07-27 1978-11-14 Bristol-Myers Company Antibacterial compositions

Also Published As

Publication number Publication date
CY1316A (en) 1986-03-28
CH648755A5 (de) 1985-04-15
IT8048512A0 (it) 1980-04-24
MY8600495A (en) 1986-12-31
ATA227880A (de) 1983-05-15
GB2118041A (en) 1983-10-26
ES490947A0 (es) 1981-05-16
MY8600498A (en) 1986-12-31
FR2455034A1 (fr) 1980-11-21
IT8048512A1 (it) 1981-10-24
HK1486A (en) 1986-01-17
JPS55149242A (en) 1980-11-20
GB2053195A (en) 1981-02-04
CY1324A (en) 1986-06-27
NL8002483A (nl) 1980-10-28
AT373235B (de) 1983-12-27
CH646948A5 (de) 1984-12-28
CA1159834A (en) 1984-01-03
DE3016110A1 (de) 1980-11-06
GB2118041B (en) 1984-03-21
FR2455034B1 (enrdf_load_stackoverflow) 1984-08-10
ES8105259A1 (es) 1981-05-16
HK21286A (en) 1986-04-04
GB2053195B (en) 1983-04-07
IT1188929B (it) 1988-01-28

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8128 New person/name/address of the agent

Representative=s name: KINZEBACH, W., DIPL.-CHEM. DR.PHIL., PAT.-ANW., 80

8127 New person/name/address of the applicant

Owner name: BRISTOL-MYERS SQUIBB CO. (N.D.GES.D.STAATES DELAWA

8128 New person/name/address of the agent

Representative=s name: KINZEBACH, W., DIPL.-CHEM. DR.PHIL. RIEDL, P., DIP

D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee